Brain Injury Journal Impact Factor & Information

Publisher: International Association for the Study of Traumatic Brain Injury; European Brain Injury Society, Informa Healthcare

Journal description

This journal covers all aspects of brain injury from basic science, neurological techniques and outcomes to vocational aspects, with studies of rehabilitation and outcome of both patients and their families. It addresses both adult and pediatric issues and it embraces issues such as family and peer relationships, effects of alcohol and drugs, communication problems and management techniques and creating new programs. Brain Injury uses case studies to illustrate different approaches to a subject, and provides a forum for the appraisal of theories which may influence future research. Brain Injury is the official journal of the International Brain Injury Association (IBIA) and the European Brain Injury Society (EBIS).

Current impact factor: 1.86

Impact Factor Rankings

2015 Impact Factor Available summer 2015
2013 / 2014 Impact Factor 1.861
2012 Impact Factor 1.513
2011 Impact Factor 1.36
2010 Impact Factor 1.75
2009 Impact Factor 1.533
2008 Impact Factor 1.116
2007 Impact Factor 1.25
2006 Impact Factor 1.182
2005 Impact Factor 1.471
2004 Impact Factor 1.136
2003 Impact Factor 1.12
2002 Impact Factor 1.043
2001 Impact Factor 0.924
2000 Impact Factor 0.914
1999 Impact Factor 1.017
1998 Impact Factor 1.085
1997 Impact Factor 1.256
1996 Impact Factor 0.843
1995 Impact Factor 0.88

Impact factor over time

Impact factor
Year

Additional details

5-year impact 2.06
Cited half-life 7.50
Immediacy index 0.38
Eigenfactor 0.01
Article influence 0.55
Website Brain Injury website
Other titles Brain injury (Online), BI
ISSN 1362-301X
OCLC 38266063
Material type Document, Periodical, Internet resource
Document type Internet Resource, Computer File, Journal / Magazine / Newspaper

Publisher details

Informa Healthcare

  • Pre-print
    • Author can archive a pre-print version
  • Post-print
    • Author cannot archive a post-print version
  • Restrictions
    • 12 months embargo
  • Conditions
    • On author's personal website or institution website
    • Publisher copyright and source must be acknowledged
    • On a non-profit server
    • Must link to publisher version
    • Publisher's version/PDF cannot be used
    • NIH funded authors may post articles to PubMed Central for release 12 months after publication
    • Wellcome Trust authors may deposit in Europe PMC after 6 months
  • Classification
    ​ yellow

Publications in this journal

  • [Show abstract] [Hide abstract]
    ABSTRACT: To study the effect of flavonoids isolated from aerial parts of Scutellaria baicalensis Georgi (SSF) on cerebral damage induced by okadaic acid (OA) in rats. OA was microinjected into the right lateral ventricle of male rats at a dose of 200 ng kg(-1) twice with a 3-day interval between injections to establish a model of Alzheimer's-disease-like cerebral damage. Neuronal morphology was observed with thionin staining and the expressions of glial fibrillary acidic protein (GFAP) and β-amyloid peptide 1-40 (Aβ1-40) were monitored via immunohistochemistry. The level of malondialdehyde (MDA) and the activities of glutathione peroxidase (GSH-Px) and lactate dehydrogenase (LDH) were measured using spectrophotometry. The results showed that OA-treated rats exhibited marked neuronal damage accompanied by increased levels of Aβ1-40 peptide and MDA accumulation, decreased GFAP protein expression and reduced GSH-Px and LDH activity in the brain. SSF at three doses (25, 50 and 100 mg kg(-1)) dramatically reversed the OA-induced changes in the brains of rats. SSF-mediated amelioration of OA-induced neuronal damage in rats provides a rationale for assessing SSF as a means of to reducing tau hyperphosphorylation and Aβ expression in the treatment of Alzheimer's disease.
    Brain Injury 06/2015; DOI:10.3109/02699052.2015.1042053
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    ABSTRACT: To assess quantitatively the effect of luminance on VEP amplitude and latency in visually-normals (VN) and patients with mild traumatic brain injury (mTBI). VN individuals (n = 20) and those with mTBI (n = 19) participated. Those with mTBI were assessed 1-10 years post-injury (mean = 4.97 years), with the exception of one subject. Pattern VEP testing was employed using the DIOPSYS™ NOVA-TR system, with a 74 cd m(-2) baseline luminance. Luminance levels were reduced with five different neutral density (ND) filters (0.5, 1.0, 1.5, 2.0 and 2.5) and compared to the baseline response. All testing was performed under binocular-viewing conditions with full refractive correction in place. In both groups, mean VEP amplitude reduced with decrease in luminance (p < 0.05). At each luminance level, the mean VEP amplitude was significantly lower in mTBI than in the VN population (p < 0.05). In both groups, the mean VEP latency increased progressively with reduction in luminance (p < 0.05), with it being significantly higher in mTBI than in the VN population (p < 0.05). High luminance levels produced an optimal VEP response in both populations. VEP amplitude was robust, whereas latency progressively increased in both groups as luminance decreased. The latency increase with decreased luminance was significantly larger in those with mTBI, thus suggesting that latency can be used to differentiate reliably between VN individuals and those with mTBI.
    Brain Injury 06/2015; DOI:10.3109/02699052.2015.1035329
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    ABSTRACT: The role of microglial activation in traumatic brain injury (TBI) has been extensively described in established animal models. In contrast, very few studies have analysed this process in human patients, the majority being focused on the local reaction in the contused parenchyma. In this work, the main objective was the analysis of microglial activation in brain regions distant from the primary lesion. Morphological changes of microglia were evaluated in the cerebral cortex of patients deceased from TBI in comparison with control subjects. Cortical samples from five cases with TBI and 10 controls were evaluated using Ricinus communis lectin histochemistry and conventional Hematoxylin-eosin staining. It was observed that microglial cells from patients with TBI presented shorter and thicker cellular projections compared with controls. Moreover, the percentage of histological area reactive to lectin was statistically higher in samples from subjects with TBI. These signs of microglial activation were observed in all of the analysed cortical areas, thus indicating a generalized effect on the whole cerebral cortex. The results are consistent with previous imaging PET studies performed in living patients with the (11)C-PK11195 radiotracer. The findings indicate that TBI induces a widespread activation of brain microglia which affects all cortical areas, including those distant from the contusion site.
    Brain Injury 06/2015; DOI:10.3109/02699052.2015.1018325
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    ABSTRACT: It is well-documented that survivors of paediatric brain tumour are at risk for neurocognitive deficits resulting in an increased interest in neurocognitive assessment for these youth. Given the scarcity of well-validated brief assessments for this purpose, this study examines the reliability and validity of a brief neurocognitive screening measure. Cross-sectional data on youth (aged 6-17.9) administered a brief neurocognitive screening device and broader neurocognitive batteries was collected via chart review to evaluate the reliability and validity of a brief neurocognitive screening device. Fifty-one youth with brain tumours and 26 youth with traumatic brain injury (TBI) were administered The Lebby-Asbell Neurocognitive Screening Examination (LANSE) during clinic visits. A sub-set of children were administered a more comprehensive neurocognitive evaluation and scores from the LANSE and these evaluations were compared to assess preliminary validity. Most LANSE sub-scales demonstrated adequate reliability and preliminary validity with some exceptions. Comparison of youth with brain tumours to those with a TBI revealed a similar pattern of potential neurocognitive impairment across several cognitive domains. This study demonstrates the preliminary reliability and validity of a brief neurocognitive screening examination for youth with brain tumours.
    Brain Injury 06/2015; DOI:10.3109/02699052.2015.1035331
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    ABSTRACT: This study investigated whether the size of the middle cranial fossa foramina reflects the severity of moyamoya disease (MMD). It compared 20 adult patients managed without surgical revascularization with 2 age- and sex-matched controls. MR angiography scores were assigned by the severity of occlusive changes of the internal carotid artery, the middle cerebral artery, the anterior and the posterior cerebral arteries and the signals of the distal branches of these arteries. These scores were stratified into MR angiography grades (Houkin's grade: 1-4). The relationships between the Houkin's grade and the size of the foramen spinosum (FS), foramen ovale, carotid canal and middle meningeal artery (MMA) were evaluated. Simple regression analysis showed the correlation between the Houkin's grade and the bilateral FS (right, r = 0.56, p = 0.010; left, r = 0.46, p = 0.044) and MMA (right, r = 0.89, p = 0.0050; left, r = 0.47, p = 0.036). It also showed the correlation between the FS and MMA (right, r = 0.53, p = 0.018; left, r = 0.55, p = 0.013). There were no significant differences between the Houkin's grade, the size of the carotid canal and the foramen ovale. The larger FS and MMA on brain CT, which might be performed for patients suspected of intracranial lesions, could aid the diagnosis of MMD.
    Brain Injury 06/2015; DOI:10.3109/02699052.2015.1035333
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    ABSTRACT: To determine whether S100B protein in serum can predict intracranial lesions on computed tomography (CT) scan after mild traumatic brain injury (MTBI). Systematic review and meta-analysis Methods and procedures: A literature search was conducted using Medline, Embase, Cochrane, Google Scholar, CINAHL, SUMSearch, Bandolier, Trip databases, bibliographies from identified articles and review article references. Eligible articles were defined as observational studies including patients with MTBI who underwent post-traumatic head CT scan and assessing the screening role of S100B protein. There was a significant positive association between S100B protein concentration and positive CT scan (22 studies, SMD = 1.92, 95% CI = 1.29-2.45, I(2) = 100%; p < 0.001). The pooled sensitivity and specificity values for a cut-point range = 0.16-0.20 µg L(-1) were 98.65 (95% CI = 95.53-101.77; I(2) = 0.0%) and 50.69 (95% CI = 40.69-60.69; I(2) = 76.3%), respectively. The threshold for serum S100B protein with 99.63 (95% CI = 96.00-103.25; I(2) = 0.0%) sensitivity and 46.94 (95% CI = 39.01-54.87; I(2) = 95.5%) specificity was > 0.20 µg L(-1). After MTBI, serum S100B protein levels are significantly associated with the presence of intracranial lesions on CT scan. Measuring the protein could be useful in screening high risk MTBI patients and decreasing unnecessary CT examinations.
    Brain Injury 06/2015; DOI:10.3109/02699052.2015.1037349
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    ABSTRACT: To examine the effect of soccer heading ball speed on S-100B serum concentration, concussion sideline assessments and linear head impact acceleration. Sixteen division I soccer players participated in this pre-test post-test design study. Athletes performed five standing headers over a 10 minute period at 30 (n = 5), 40 (n = 5) or 50 (n = 6) miles per hour (mph) (randomized). S-100B serum concentration (ng mL(-1)) and sideline concussion assessments were measured prior to and post-heading. Peak resultant linear head acceleration (gravitational units; g) was measured during soccer heading. No statistically significant interaction effects were identified between ball velocity groups over time on S100B (effect sizes ranged from 0.03-0.23) or concussion assessments tests. There was a non-significant increase (p = 0.06) in head impact acceleration from the 30 (30.6; SD = 6.2 g) to 50 mph (50.7; SD = 7.7 g) ball speed. In this controlled setting, an acute bout of soccer heading across various ball velocities did not affect S100B or concussion assessment test scores. These findings are preliminary, as the small sample size in each group may have played a role in the lack of significant findings.
    Brain Injury 05/2015; DOI:10.3109/02699052.2015.1035324
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    ABSTRACT: Participation is considerably restricted in children and adolescents with acquired brain injury (ABI) as compared to their healthy peers. This systematic review aims to identify which factors are associated with participation in children and adolescents with ABI. A systematic search in Medline and various other electronic databases from January 2001-November 2014 was performed. All clinical studies describing determinants of participation at least 1 year after the diagnosis of ABI by means of one or more pre-defined instruments in patients up to 18 years of age were included. Extracted data included study characteristics, patient characteristics, participation outcome and determinants of participation (categorized into: health conditions (including characteristics of ABI), body functions and structures, activities, personal factors and environmental factors). The methodological quality of the studies was evaluated based on three quality aspects (selection, information and statistical analysis bias) and scored as low, moderate or high. Eight studies using an explicit participation outcome measure were selected after review, including a total of 1863 patients, with a follow-up ranging from 1 up to 288 months. Three studies included patients with a traumatic or a non-traumatic brain injury (TBI or NTBI) and five studies with only TBI patients. Factors consistently found to be associated with more participation restrictions were: greater severity of ABI, impaired motor, cognitive, behavioural and/or sensory functioning, limited accessibility of the physical environmentand worse family functioning. Fewer participation problems were associated with a supportive/nurturing parenting style, higher household income, acceptance and support in the community and availability of special programmes. The overall methodological quality of the included studies was high in two and moderate in six studies. This systematic review shows that only a few, moderate quality, studies on the determinants of participation after paediatric ABI using recommended explicit measurement instruments are available. Various components of the ICF model: health condition, body functions and structures and environmental factors were consistently found to be associated with participation. More methodologically sound studies, using the recommended explicit outcome measures, a standardized set of potential determinants and long-term follow-up are suggested to increase the knowledge on participation in children and youth with ABI.
    Brain Injury 05/2015; DOI:10.3109/02699052.2015.1034178
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    ABSTRACT: Information is scant concerning enduring brain injury effects of participation in the contact sport of Rugby Union (hereafter rugby) on early adolescents. The objective was prospectively to investigate differences between young adolescent male rugby players and non-contact sports controls on neurocognitive test performance over 3 years and academic achievement over 6 years. A sample of boys from the same school and grade was divided into three groups: rugby with seasonal concussions (n = 45), rugby no seasonal concussions (n = 21) and non-contact sports controls (n = 30). Baseline neurocognitive testing was conducted pre-season in Grade 7 and post-season in Grades 8 and 9. Year-end academic grades were documented for Grades 6-9 and 12 (pre-high school to year of school leaving). A mixed model repeated measures ANOVA was conducted to investigate comparative neurocognitive and academic outcomes between the three sub-groups. Compared with controls, both rugby groups were significantly lower on the WISC-III Coding Immediate Recall sub-test. There was a significant interaction effect on the academic measure, with improved scores over time for controls, that was not in evidence for either rugby group. Tentatively, the outcome suggests cognitive vulnerability in association with school level participation in rugby.
    Brain Injury 05/2015; DOI:10.3109/02699052.2015.1031699
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    ABSTRACT: To describe differences in outpatient follow-up and academic accommodations received by children with and without persistent post-concussion symptoms (PPCS) after emergency department (ED) evaluation. It was hypothesized that children with PPCS would have more outpatient visits and receive academic accommodations more often than children without PPCS and that follow-up would be positively associated with receiving accommodations. Children aged 8-18 years with acute (≤6hours) concussion at time of presentation to a paediatric ED were enrolled in an observational study. Outcomes were assessed through a telephone survey 30 days after injury. Of 234 enrolled participants, 179 (76%) completed follow-up. PPCS occurred in 21%. Only 45% of subjects had follow-up visits after ED discharge. Follow-up visit rates were similar for those with and without PPCS (58% vs. 41%, respectively; p = 0.07). Children with PPCS missed twice as many school days as those without (3 vs. 1.5; p < 0.001), but did not differ in receiving academic accommodations (36% vs. 53%; p = 0.082). Outpatient follow-up was associated with receiving academic accommodations (RR = 2.2; 95% CI = 1.4-3.5). Outpatient follow-up is not routine for concussed children. Despite missing more school days, children with PPCS do not receive academic accommodations more often. Outpatient follow-up may facilitate academic accommodations.
    Brain Injury 05/2015; DOI:10.3109/02699052.2015.1035325
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    ABSTRACT: To extend previous observations by investigating if differences exist in time to initiation or to recovery of total oral intake in patients with acquired brain injury assessed by either Facial-Oral Tract Therapy (F.O.T.T.®) or Fibreoptic Endoscopic Evaluation of Swallowing (FEES) and to investigate whether other factors influence these outcomes. Randomized controlled trial. One hundred and nineteen patients with dysphagia in inpatient neurorehabilitation were randomized. The main outcome was time to maximum on the Functional Oral Intake Scale. There was no difference in time to initiation or recovery of total oral intake using F.O.T.T.® or FEES. Oral intake was initiated for 42% on admission and 92% at discharge; 2.5% of the patients were on total oral intake within 24 hours of admission and 37% at discharge. The likelihood of recovery to total oral intake before discharge was found to depend on age, Functional Independence Measure score, length of stay and number of dysphagia interventions. There was no significant difference in time to initiation and recovery of total oral intake before discharge, whether assessed by F.O.T.T.® or FEES, indicating that an instrumental assessment is unnecessary for standard evaluation. Age, functional independence and length of stay had a significant influence.
    Brain Injury 05/2015; DOI:10.3109/02699052.2015.1022883
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    ABSTRACT: This preliminary investigation studies selected aspects of validity of the Upper Limb Performance Analysis (ULPA), an occupation-based functional upper limb (UL) measure. The study investigated the ULPA-Task Performance Mastery (ULPA-TPM) in 35 community dwelling adults with upper motor neuron syndrome following acquired brain injury and 26 healthy controls. Construct and concurrent validity of the ULPA were determined via group discrimination between adults with and without ABI; and ABI participants who were and were not referred for UL spasticity management with botulinum toxin-A injections (injected and non-injected group). Concurrent validity was examined by investigating the relationships between the ULPA and an existing functional UL measure, the Action Research Arm Test, using Spearman's rank-order correlation. Significant differences in UL performance were demonstrated between the ABI and the Control group on all ULPA sub-scales (including: Omission (z = -2.6 to -3.6, rspb = 0.37-0.48), Accuracy (z = -5.8 to -6.0, rspb = 0.78-0.82), Repetition (z = -5.1 to -5.4, rspb = 0.63-0.73) and Timing errors (z = -5.9 to -6.2, rspb = 0.77-0.88). Those in the Injected group demonstrated more task performance errors than the Non-injected group, with significant differences in Accuracy (z = -2.1 to -2.4, rspb = 0.37-0.45), Repetition (z = -2.5 to -2.1, rspb = 0.43) and Timing (z = -2.0, rspb = 0.37). This study demonstrated good construct and concurrent validity of the ULPA-TPM.
    Brain Injury 05/2015; DOI:10.3109/02699052.2015.1028446
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    ABSTRACT: To investigate trajectories and predictors of trajectories of anxiety and depression in relatives of patients with a severe brain injury during the first year after injury. A prospective longitudinal study with four repeated measurements. Ninety relatives of patients with severe brain injury. The relatives were assessed on the anxiety and depression scales from the Symptom Checklist-90-Revised and latent variable growth curve models were used to model the trajectories. The effects of patient's age, patient's Glasgow Coma Score, level of function and consciousness, gender and relationship of the relatives were modelled. Improvement was found in both symptoms of anxiety and depression during the 12-month study period. The analysis revealed different trajectories for symptoms of anxiety and depression, as anxiety had a more rapid improvement. Higher initial level of symptoms of depression was seen in female relatives. Higher initial level of anxiety was associated with younger patient age, lower level of function and consciousness in the patient and the relative being female or the spouse. Future research and interventions should focus not only on specific deficits in the patient, but also on how the emotional state and well-being of the relatives evolve, while trying to adjust and cope with a new life-situation.
    Brain Injury 05/2015; DOI:10.3109/02699052.2015.1016451
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    ABSTRACT: Primary objective and hypothesis: To test the hypothesis that there is a significant relationship between WeeFIM ratings of cognitive functioning and performance on neuropsychological tests of children with traumatic brain injury (TBI). Retrospective analysis of archival data. Data from 52 children with severe TBI collected during inpatient rehabilitation. Multiple regression analysis with Neuropsychological test scores from Wechsler Abbreviated Scale of Intelligence (WASI) and Children's Memory Scale (CMS) entered as predictor variables and WeeFIM cognitive ratings as criteria variables. Analyses revealed significant relationships between WeeFIM cognitive rating and neuropsychological test scores. Delayed verbal memory was most highly associated with WeeFIM cognitive ratings. Results support the hypothesis of significant relationships between neuropsychological performance and WeeFIM ratings of children with TBI and support generalizability of neuropsychological performance to daily cognitive functioning.
    Brain Injury 05/2015; DOI:10.3109/02699052.2015.1022881
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    ABSTRACT: This prospective longitudinal study aimed to identify rates and predictors of productivity outcomes (educational or vocational) at 1 year post-injury in young people studying prior to sustaining a traumatic brain injury (TBI). A total of n = 145 with complicated mild-severe injuries, studying at secondary (45.2%) or tertiary (54.8%) levels pre-injury, participated. Mean age at injury = 18.6 years (SD = 3.29) and mean duration of PTA = 21.9 days (SD = 27.18). Pre-injury demographic (gender, age, level of study, living situation), injury related (severity, physical injuries) and concurrent post-injury (independence in ADLs and self-reported cognitive, behavioural, emotional sequelae) predictors were entered into logistic regressions. Of those participants categorized as 'productive' (79.3%), 60% were studying, with 40% employed. Participants with longer PTA and those with reduced initiative and self-centredness were less likely to be 'productive'. The overall relationship between PTA and productivity appeared to be linear in nature, with PTA duration of more than 80 days, reducing the probability of being productive at 1 year to 50%. PTA duration and behavioural sequelae were the strongest predictors of productivity in those studying prior to injury. Allied health supports should be targeted towards reducing the impact of and compensating for barriers such as reduced initiative in order to maximize productive outcomes in this group.
    Brain Injury 05/2015; DOI:10.3109/02699052.2015.1022882