Acta dermatovenerologica Alpina, Panonica, et Adriatica

Description

  • Impact factor
    0.00
  • 5-year impact
    0.00
  • Cited half-life
    0.00
  • Immediacy index
    0.00
  • Eigenfactor
    0.00
  • Article influence
    0.00
  • Website
    Acta Dermatovenerologica Alpina, Pannonica et Adriatica website
  • Other titles
    Acta dermatovenerologica Alpina, Pannonica, et Adriatica
  • ISSN
    1318-4458
  • OCLC
    32565749
  • Material type
    Periodical, Internet resource
  • Document type
    Journal / Magazine / Newspaper, Internet Resource

Publications in this journal

  • [Show abstract] [Hide abstract]
    ABSTRACT: Cutaneous adverse reactions to antiepileptic drugs (AEDs) are usually easily recognized in daily clinical practice when they manifest as a morbilliform or maculopapular rash within the first few weeks after introducing an AED. Valproate (VPA)-induced encephalopathy is a rare but serious complication, presenting with impaired consciousness, with or without hyperammonemia, normal liver enzymes, and normal serum level of VPA. A 2-year-old Caucasian boy with severe developmental disability and pharmacoresistant epilepsy presented with fever, generalized erythrodermia, and encephalopathy, which resolved after discontinuation of valproate. Sodium valproate (30 mg/kg/day) was introduced 5 months previously, as the third drug in combination with vigabatrin and levetiracetam, due to frequent daily seizures. The clinical condition of generalized erythrodermia and encephalopathy was recognized by the treating physician as a possible adverse reaction to VPA: with the Naranjo scale it was probably associated with VPA (six points) and possibly associated with vigabatrin and levetiracetam (three and two points, respectively). After valproate withdrawal, the patient recovered completely. This case is of interest because erythrodermia was a clue to the recognition of valproate-related adverse reaction with severe central nervous system involvement without hyperammonemia and with normal liver enzymes-a very rare occurrence.
    Acta dermatovenerologica Alpina, Panonica, et Adriatica 06/2014; 23(2):35-8.
  • [Show abstract] [Hide abstract]
    ABSTRACT: Epidermolysis bullosa simplex with mottled pigmentation is a rare subtype of epidermolysis bullosa simplex that is characterized by nonscarring blistering and reticulated hyperpigmentation. We report the first Slovenian case of a newborn with blisters, who later presented with hyperpigmented macules in the first year of life. A missense p.Pro25Leu mutation in the KRT5 gene was confirmed.
    Acta dermatovenerologica Alpina, Panonica, et Adriatica 06/2014; 23(2):33-4.
  • [Show abstract] [Hide abstract]
    ABSTRACT: Elastosis perforans serpiginosa is a rare skin disease in which abnormal elastic fibers, other connective tissue elements, and cellular debris are expelled from the papillary dermis through the epidermis. Three clinical variants of EPS can be detected: idiopathic, reactive, and drug-induced. Clinically it consists of small horny or umbilicated papules arranged in a linear, arciform, circular, or serpiginous pattern. It usually occurs in young adults and shows a predilection for the head and neck. The lesions are generally asymptomatic or slightly itching. Several treatments have been reported with poor long-term success; these include intralesional and topical corticosteroids, tazarotene, imiquimod, and cryotherapy. We report a case of 40-year-old black woman affected by elastosis perforans serpiginosa that was referred to our department and treated with intralesional injections of triamcinolone acetonide and topical application of allium cepa-allantoin-pentaglycan gel.
    Acta dermatovenerologica Alpina, Panonica, et Adriatica 06/2014; 23(2):39-41.
  • [Show abstract] [Hide abstract]
    ABSTRACT: Abstract Acroangiodermatitis (pseudo-Kaposi's sarcoma, AAD) is a benign vascular dermatosis that resembles Kaposi's sarcoma clinically and histopathologically (1). Four types have been defined: the Stewart-Bluefarb type accompanying chronic arteriovenous malformations, the Mali type accompanying stasis dermatitis, a type accompanying the first gestation, and a type accompanying arteriovenous shunts in patients with chronic kidney failure (3). Although AAD development is associated with chronic venous failure, less frequently AAD can develop as a complication of extremity paralysis, hemodialysis, post-traumatic arteriovenous fistula, amputated extremities, and vascular malformations (e.g., Klippel-Trénaunay syndrome). Pseudo-Kaposi's sarcoma can be histopathologically and clinically confused with malignant diseases such as Kaposi's sarcoma (1, 4). A 22-year-old male was referred to our outpatient clinic with a complaint of a non-healing wound on the distal phalanx of the left first toe. The patient was referred to various centers for 2 years and stated that he had received infection treatments but that his complaints did not disappear. An AAD diagnosis was established for the patient based on clinical and histopathologic evidence. Because he had early-onset disease and it was unilateral, the diagnosis was delayed. In addition, due to the rare occurrence of the disease, we histopathologically diagnosed this patient as having acroangiodermatitis.
    Acta dermatovenerologica Alpina, Panonica, et Adriatica 06/2013;
  • Acta dermatovenerologica Alpina, Panonica, et Adriatica 01/2013; 22:21-25.
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: The study was designed to utilize the SF-36, a validated generic questionnaire, to assess acne patients' view of their general health and quality of life. The subjects were 454 acne patients (237 males, 217 females) visiting an outpatient clinic at Qassim University. An Arabic translation of the SF-36 questionnaire, culturally adapted and validated, was used to assess eight life-quality dimensions. Data regarding demographics, disease grade, duration, and treatment were also included in the questionnaire. The internal consistency reliability of the multi-item scales was assessed using Cronbach's coefficient alpha. Descriptive statistics were conducted with independent and paired-sample t-tests as well as one-way ANOVA for metric variables; and Xi(2) and Fisher's exact tests were used for categorical variables. Spearman's rank correlation was used for associations. All tests were two-sided, and the level of significance was set at phi < 0.05. The scores for physical functioning, role physical, role emotional, and vitality dimensions were below 60%. About 81.5% of respondents rated their health as either "fair" or "poor", and only 25% said their general health was better than the previous year. Females were more likely to report better general health than males (phi = 0.001). Education level negatively correlated with mental health, role emotional, social functioning, general health, and bodily pain. Rural patients showed better general health (phi = 0.003). Married persons rated their general health better than single patients (phi = 0.002). Mild and shorter-duration acne was associated with a better general health score compared to the previous year (phi = 0.01 and 0.001, respectively). Patients that had received treatment were significantly better regarding role physical, vitality, and mental health dimensions, whereas topical treatment was significantly better in the vitality dimension than oral therapy. The patients treated also rated their general health better than the previous year (phi = 0.0001). The presence of acne vulgaris per se is the most significant factor underlying patients' low perception of their general health. Patients' education about the disease and social support play a considerable role in better disease perception and can improve patients' quality of life.
    Acta dermatovenerologica Alpina, Panonica, et Adriatica 12/2009; 18(4):157-64.
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: A cutaneous horn is a conical, dense, hyperkeratotic protrusion that often appears similar to the horn of an animal. It is a morphologic designation referring to an unusually cohesive keratinized material, not a true pathologic diagnosis. Cutaneous horns occur in association with, or as a response to, a wide variety of underlying benign, pre-malignant, and malignant cutaneous diseases. The most important common concern is distinguishing a hyperkeratotic actinic keratosis from a cutaneous squamous cell carcinoma. Keratoacanthoma is another cause, as illustrated herein as a projective cutaneous tumor with a fingernail-like appearance. The treatment of choice for cutaneous horns is shave excision with subsequent histopathologic evaluation to rule out underlying malignancy and to guide potential further therapy.
    Acta dermatovenerologica Alpina, Panonica, et Adriatica 12/2009; 18(4):189-93.
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: hidradenitis suppurativa (HS) is a chronic inflammatory, suppurating, fistulizing, and scar-producing disease of apocrine gland-bearing skin. The diagnosis is primarily clinical, based on the presence of both sinus tracts and abscesses with a characteristic distribution. Review of epidemiological, clinical, and prognostic characteristics of HS and discussion of the etiopathogenic aspects of this chronic problem. We retrospectively report all cases of HS followed at the Department of Dermatology between January 1985 and December 2008. Eleven patients (10 male and 1 female), with a mean age of 35.2 years (range 21 dash, vertical53 years) at HS diagnosis were followed for HS. The average age of disease onset was 23.9 years. The median delay between onset of symptoms and diagnosis was 144 months (range 1 dash, vertical408 months). Clinical features showed inflamed discharging papules or nodules, painful tender erythematous nodules, and double-ended comedones. The disease mainly affected the axillary, anal, perineal, and genital areas. Histologically, dermal features showed active folliculitis or abscess, sinus tract formation, fibrosis, and granuloma formation. Pathological associations (Darier's disease and Down syndrome) were noted in two patients. Treatment consisted of antibiotics in eight patients, retinoids (1 mg/kg/ day) in three patients, and surgery in three patients. The mean follow-up was 13 months (range 2 dash, vertical30 months). Recurrence of lesions was observed in all patients approximately 1 month after treatment withdrawal. The Down syndrome patient developed vaginal hydrocele of the testis as a complication of his staphylococcic ulcers. In all cases healing occurred with substantial scarring. An obvious male predominance was noted in our patients as well as a delay in the diagnosis of HS, which could be explained by non-recognition of the disease by non-specialists that see the patients at the primary-care level.
    Acta dermatovenerologica Alpina, Panonica, et Adriatica 12/2009; 18(4):165-72.
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Lupus vulgaris (LV) is a rare form of cutaneous mycobacterial infection in children. Most cases follow hematogenous or lymphatic seeding, and more rarely from exposure to bacillus Calmette- Guérin (BCG) vaccine. We report a child that received BCG vaccination and developed LV 2 months later.
    Acta dermatovenerologica Alpina, Panonica, et Adriatica 12/2009; 18(4):195-7.
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Lymphangioma circumscriptum (LC) is a form of lymphangioma involving skin and subcutaneous tissue. It is evident as translucent vesicles of varying size, though commonly 2 to 4 mm, and of a pink, red, or black hue. It is localized to the dermis, frequently extending deeply and laterally. LC may resemble other entities, such as metastatic carcinoma of the skin, lymphangiectasis, or herpes zoster. We report an unusual verruciform, zosteriform form of LC.
    Acta dermatovenerologica Alpina, Panonica, et Adriatica 12/2009; 18(4):179-82.
  • Acta dermatovenerologica Alpina, Panonica, et Adriatica 12/2009; 18(4):199.
  • [Show abstract] [Hide abstract]
    ABSTRACT: Pathological conditions of the hymen are rare in everyday medical practice. They are usually encountered in the pediatric patient population and are sometimes a matter of forensic interest. We report an interesting case of a large hymenal polyp in an adolescent virgin that presented only a cosmetic problem. The polyp was excised, the hymenal ring was preserved, and the sample was histologically verified.
    Acta dermatovenerologica Alpina, Panonica, et Adriatica 12/2009; 18(4):173-5.
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Familial hypercholesterolemia, a form of primary hyperlipoproteinemia, is an autosomal dominant disorder characterized by an increase in serum LDL cholesterol concentrations. Multiple types of xanthomas occur, such as tendinous, tuberous, subperiosteal, and xanthelasma. Intertriginous xanthomas are rare, but if present are pathognomonic in this disorder. We report a patient with multiple xanthomas including the very rare intertriginous variety.
    Acta dermatovenerologica Alpina, Panonica, et Adriatica 12/2009; 18(4):183-7.