Anadolu kardiyoloji dergisi: AKD = the Anatolian journal of cardiology

Description

  • Impact factor
    0.72
  • 5-year impact
    0.58
  • Cited half-life
    3.40
  • Immediacy index
    0.35
  • Eigenfactor
    0.00
  • Article influence
    0.12
  • ISSN
    1308-0032

Publications in this journal

  • Anadolu kardiyoloji dergisi: AKD = the Anatolian journal of cardiology 05/2014;
  • Anadolu kardiyoloji dergisi: AKD = the Anatolian journal of cardiology 05/2014;
  • Anadolu kardiyoloji dergisi: AKD = the Anatolian journal of cardiology 05/2014;
  • Anadolu kardiyoloji dergisi: AKD = the Anatolian journal of cardiology 05/2014;
  • Anadolu kardiyoloji dergisi: AKD = the Anatolian journal of cardiology 05/2014;
  • Anadolu kardiyoloji dergisi: AKD = the Anatolian journal of cardiology 05/2014;
  • Anadolu kardiyoloji dergisi: AKD = the Anatolian journal of cardiology 05/2014;
  • Anadolu kardiyoloji dergisi: AKD = the Anatolian journal of cardiology 05/2014;
  • Anadolu kardiyoloji dergisi: AKD = the Anatolian journal of cardiology 05/2014;
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    ABSTRACT: Previous studies have shown a significant negative association between diabetes and abdominal aortic aneurysm. However, the relation of diabetes to coronary artery ectasia (CAE) has not well established. The aim of the current study was to conduct a systemic review for evaluating the relationship between diabetes and CAE. A systemic search of electronic databases (PUBMED, EMBASE, OVID, WEB OF SCIENCE, THE COCHRANCE LIBRARY) from 1970 to March 2013 was performed. Additionally, checking reference lists from identified articles, reviews, and the abstracts presented at related scientific meetings were also carried out. All case-control studies investigating appropriate prevalence data were included. Among 328 articles, 10 case-control studies were finally identified. The prevalence of diabetes in studied patients with CAE was 8% to 33%, while in those without CAE was ranged from 13.5% to 35%. Pooled analysis showed a reduced rate of diabetes amongst patients with CAE compared to those without (OR 0.65, 0.54-0.77, p<0.0001). Our findings suggested that diabetes might play a protective role for the development of CAE, indicating that further study is needed to evaluate the association diabetes and CAE including underlying mechanisms and future medical interventional strategies.
    Anadolu kardiyoloji dergisi: AKD = the Anatolian journal of cardiology 05/2014;
  • Anadolu kardiyoloji dergisi: AKD = the Anatolian journal of cardiology 05/2014;
  • [Show abstract] [Hide abstract]
    ABSTRACT: Left ventricular hypertrophy (LVH) is a structural remodeling of the heart developing as a response to volume and/or pressure overload. Previous studies have shown that hypertension is not an independent factor in the development of LVH and occurrence does not depend on the length and severity of hypertension, but the role played by other comorbidities such as triglycerides, age, gender, genetics, insulin resistance, obesity, physical inactivity, increased salt intake and chronic stress. LVH develops through three phases: adaptive, compensatory, and pathological phase. Contractile dysfunction is reversible in the first two phases and irreversible in the third. According to the Framingham study, LVH develops in 15-20% of patients with mild arterial hypertension, and in 50% of patients with severe hypertension. The pathophysiology of LVH includes hypertrophy of cardiomyocytes, interstitial and perivascular fibrosis, coronary microangiopathy and macroangiopathy. Individuals with LVH have 2-4 times higher risk of having adverse CV events compared to patients without LVH.
    Anadolu kardiyoloji dergisi: AKD = the Anatolian journal of cardiology 05/2014;
  • Anadolu kardiyoloji dergisi: AKD = the Anatolian journal of cardiology 05/2014;
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    ABSTRACT: The evaluation of pulmonary vascular reactivity plays a significant role in the management of patients with pulmonary hypertension. Inhaled nitric oxide in combination with oxygen (O2) has become widely used as an agent for pulmonary vasodilator testing. However, inhaled nitric oxide is not available in many developing countries. Recently, aerosolized iloprost was suggested as an alternative to nitric oxide for this purpose. In the present study, aerosolized iloprost was used together with O2 in the pulmonary vasoreactivity test of children with severe pulmonary hypertension. Thus, the synergistic effect of both vasodilators was utilized without extending the duration of cardiac catheterization. The prospective cohort study registered a total of 16 children with severe pulmonary hypertension whose median age was 4.5 years. Hemodynamic parameters were quantified before and after the vasoreactivity test. Increased left-to-right shunt, pulmonary vascular resistance of <6 Woods units (WU). /m2 and a pulmonary-systemic resistance ratio of <0.3, as well as a decrease >10% in the pulmonary vascular resistance and pulmonary-systemic vascular resistance ratio after the vasoreactivity test were accepted as a positive response. The data were analyzed using Wilcoxon signed-rank and the Mann-Whitney U tests. Eleven children gave a positive response to the vasoreactivity test, while 5 children did not respond. Pulmonary vascular resistance dropped from 9.98±1.39 WU./m2 to 5.08±1.05 WU./m2 (p=0.013) and the pulmonary-systemic vascular resistance ratio fell from 0.68±0.08 to 0.32±0.05 (p=0.003) in the children who were responsive. No side effects were observed related to iloprost administration. Administration of inhaled iloprost in combination with O2 for pulmonary vasoreactivity testing can be useful for correctly identifying pulmonary vasoreactivity without extending the duration of cardiac catheterization.
    Anadolu kardiyoloji dergisi: AKD = the Anatolian journal of cardiology 04/2014;
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    ABSTRACT: During the course of chronic obstructive pulmonary disease (COPD), pulmonary hypertension (PH) and right ventricular (RV) failure may develop due to elevated afterload of the RV. In those patients, exercise capacity is reduced due to pulmonary and cardiac limitations. We investigated relationships between serum N-terminal of proB-type natriuretic peptide (NT-proBNP) and RV functions with exercise capacity and quality of life in patients COPD. An observational case-control study was conducted. We enrolled 31 moderate and severe COPD patients, and 20 subjects without chronic diseases as control group. Parameters reflecting the right ventricular diastolic and systolic functions by echocardiography along with serum NT-proBNP levels were assessed. Cardiopulmonary exercise testing and Short Form-36 (SF-36) were applied. Serum NT-proBNP levels were higher in COPD patients than control group (p=0.003). Serum NT-proBNP level was found to be related with pulmonary arterial pressure. Serum NT-proBNP levels were negatively correlated with anaerobic threshold oxygen uptake (AT VO2) and peak oxygen uptake (PVO2) values. Early ventricular filling velocity (Em) was lower in COPD patients. Em wave was significantly correlated with O2 pulse. There was a positive relationship between tricuspid E/A ratio and VO2 value at AT. SF-36 domains of physical functioning, general health and role limitation due to physical disorder were significantly correlated with AT VO2, PVO2 and O2 pulse. Exercise limitation may be predicted by assessment of right ventricule functions and NT-proBNP levels and exercise limitation impairs quality of life in COPD patients.
    Anadolu kardiyoloji dergisi: AKD = the Anatolian journal of cardiology 04/2014;
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    ABSTRACT: This study was aimed to investigate the effects of olmesartan or nebivolol treatment on blood pressure and some endothelial function markers in newly diagnosed patients with stage 1 essential hypertension. This randomized open label study included 85 newly diagnosed patients with stage 1 hypertension (50 males, mean age: 52±9 years). Blood pressure, flow mediated vasodilatation (FMD) and echocardiographic measurements of the patients were taken before and 8 weeks after the beginning of treatment with olmesartan or nebivolol. Nitric oxide, plasminogen activator inhibitor 1 (PAI-1) and C reactive protein (CRP) levels measured in serum samples before and after treatment, were compared. Basal variables that can affect the antihypertensive response were evaluated by multivariate logistic regression analysis. The reduction observed in the systolic and diastolic blood pressures after antihypertensive treatment was significant (p<0.05). FMD was significantly improved after treatment in both nebivolol and olmesartan groups; however, there was no significant difference between nebivolol and olmesartan groups (p=0.6). While CRP and PAI-1 levels decreased, nitric oxide levels increased in both nebivolol and olmesartan treatment groups; but these changes were not statistically significant. No drug related complication was observed. This study has indicated that olmesartan and nebivolol causes similar changes in blood pressure response, FMD FMD and endothelial function biomarkers improved. These results suggest that antihypertensive treatment, independent of the medication used, is associated with endothelial function improvement.
    Anadolu kardiyoloji dergisi: AKD = the Anatolian journal of cardiology 04/2014;
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    ABSTRACT: This experimental study aims to investigate whether radiotherapy (RT) plus trastuzumab (T) followed by subsequent hormonotherapy increase the cumulative toxic effect on cardiac functions in rats. A total of 70 Wistar Albino female rats with a mean weight 213±27 g were randomly divided into equal seven groups. The first group (C) underwent no procedure. The second group (RT) underwent the whole thoracic radiation including heart. The third group (T) was administered T through tail vein alone. The fourth group (RT+T+Tx) was administered T initially and the whole thoracic radiation at two hours, followed by tamoxifen at one week. The fifth group (RT+T+Le) was administered T and then underwent thoracic radiation, followed by letrozole. The sixth group (T+RT+An) was administered T and then underwent thoracic radiation, followed by anastrazole. The seventh group (T+RT+Ex) was administered T and then underwent thoracic radiation, followed by exemestane at one week. Hormonotherapy was administered to the rats in the Group 5, 6 and 7, as indicated in the Group 4. Radiation therapy was administered following T treatment at two hours as a single 12 Gy fraction. After the rats were sedated under anesthesia and sacrificed at 24 weeks, cardiac tissues were removed. Serial sections obtained following paraffin blockage were stained and the ratio of myocardial fibrosis was assessed. According to statistical analyses by the one-way ANOVA test and Tukey HSD test, a significant difference between test components. At the end of the study, no loss and adverse effects were seen in any group. There was a statistically significant difference among atrium, ventricle and aorta (p<0.001). The mean value of fibrosis scores increased in the rats which underwent RT. In the assessment of atrium, a significant difference was found between RT group and RT+T+An group and also T group and RT+T+Fe group (p<0.001). In the assessment of ventricule, a statistically significant difference was observed among RT, RT+T+An and RT+T+Ex. In the assessment of aorta, the scores of RT group was significantly higher than RT+T+An and RT+T+Ex. A statistically significant difference was observed among these groups (p<0.001). Our study results suggested that there was no significant additional cardiotoxicity of adjuvant hormonotherapy following concomitant RT and T treatment, compared to RT in terms of cardiac fibrosis.
    Anadolu kardiyoloji dergisi: AKD = the Anatolian journal of cardiology 04/2014;

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