Journal of Addictive Diseases (J ADDICT DIS )

Publisher: American Society of Addiction Medicine


The Journal of Addictive Diseases is jam-packed with discussions of contemporary issues vital to greater understanding and treatment of alcohol and substance abuse. In addition to providing the most current information on addictive diseases available, this important journal is: the only theme-oriented journal in the addictive disease field that focuses on clinical research and treatment, filled with in-depth bibliographies for clinicians' access to additional helpful information, devoted to featuring state-of-the-art research and clinical applications of prominent researchers and leaders in the substance abuse field, an ideal resource for the desks of physicians, psychiatrists, and therapists specializing in addictions and addictions treatment, as well as researchers, clinical experts, and professors interested in the timely topic of alcoholism/substance abuse. This journal, the essential publication for today's addiction professional, is a highly practical resource that will help you stay on top of the scientific issues and the clinical skills necessary for effective practice. It provides an integrated, multi-specialty perspective on clinically relevant research, treatment, and public policy for specialists in addiction medicine. The only theme-oriented journal in the addiction field focusing on clinical research and treatment, the Journal of Addictive Diseases devotes entire issues to the current, most important topics in addiction medicine. Nationally prominent researchers and leaders in the field contribute articles featuring state-of-the-art research and applications. Some of the timely topics covered in past issues of the Journal of Addictive Diseases include: successful strategies in drug abuse epidemiology, methods for decreasing drug dependent persons' risk for AIDS, research on alcoholism from treatment communities, potential addiction of typically abused drugs, the relationship between AIDS and substance abuse, alcohol and drug abuse in affluent sections of society, dual addiction and the problems faced by these addicts, evaluation of drug treatment programs, effects of maternal alcohol and drug abuse on newborn babies.

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  • Website
    Journal of Addictive Diseases website
  • Other titles
    Journal of addictive diseases
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    Periodical, Internet resource
  • Document type
    Journal / Magazine / Newspaper, Internet Resource

Publications in this journal

  • [Show abstract] [Hide abstract]
    ABSTRACT: Abstract Youth substance abuse is widely recognized as a major public health issue in Thailand. This study explores family and community risk and protective factors relevant to alcohol and illegal drug misuse in 1,778 Thai teenagers. Strong family attachment and a family history of antisocial behaviors were strongly associated with nearly all forms of substance abuse, with adjusted ORs ranging from 5.05 to 8.45. Community disorganization was strongly associated with self-reported substance use, although involvement in prosocial activities acted as a protective factor. The findings suggest that interventions that promote family cohesion and encourage community involvement may have considerable benefits in reducing substance abuse in Thai adolescents.
    Journal of Addictive Diseases 12/2014;
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    ABSTRACT: Abstract In an effort to inquiry 'self-medication hypothesis' in chronic psychosis and bipolar disorder heroin dependent patients a naturalistic comparative cohort study was designed with the aim of comparing, according to the presence of dual diagnosis, the clinical characteristics of heroin-dependent patients presenting for their first AOT. The main finding was that addictive (heroin) illness was more severe in bipolar 1 patients and less severe in chronic psychotic patients when compared with heroin-dependent patients without dual diagnosis. In the case of chronic psychotic patients, these differences do not allow us to exclude a therapeutic heroin use, at least at the beginning of their toxicomanic career, with limited progression of their addictive disease. This occurrence seems to be excluded for bipolar 1 heroin-dependent patients, who come to their first AOT with a more severe addictive disease.
    Journal of Addictive Diseases 11/2014;
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    ABSTRACT: Abstract Objective: This exploratory study examines the characteristics of patients in community treatment for substance use disorders in New York who self-reported as military veterans, their sources of referral and treatment outcomes. Method: Treatment records for patients in New York State programs were utilized and consisted of individual treatment records from 1995 to 2012, in which 81,471 patients have a veteran status, and 1,260,618 are non-veterans. Results: Compared with non-veterans, veterans in community treatment tend to be male, older, better educated, and more likely to have income from employment. In addition, veterans are more likely to enroll in inpatient programs, report alcohol as their primary substance of abuse, and have a somewhat higher rate of treatment completion than non-veterans. Among veterans, ethnic/racial and cultural background may play a role in their patterns of substance use and treatment participation. Specifically, more white veteran patients have alcohol, more black veterans have crack/cocaine, and more Hispanic veterans have heroin as their primary substance at admission to treatment and are the most likely to enroll in methadone programs. Conclusions: Results indicate that veterans in community-based SUD treatment have distinctive demographic characteristics, primary substance use, and treatment participation. More in-depth research is needed to examine veterans' pathways into community treatment their perception of and experience with treatment services, the likely influence of cultural background, and the role of specific military experiences on their treatment outcomes.
    Journal of Addictive Diseases 11/2014;
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    ABSTRACT: Abstract This study examines causes of death, years of life lost, and health and drug use characteristics associated with mortality over an 8-10 year period in a sample of methamphetamine (MA) users who had and had not received substance use disorder treatment (N=563). Decedents reported initiating their MA use for different reasons than surviving MA users, and some of these differences varied by treatment status. Study findings provide additional detail on long-term health and mortality outcomes in a diverse sample of MA users, which may inform public health strategies targeting the comparable and divergent needs of treated and untreated populations.
    Journal of Addictive Diseases 11/2014;
  • Journal of Addictive Diseases 04/2014; 33(2):174-175.
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    ABSTRACT: No abstract available for this article.
    Journal of Addictive Diseases 10/2010; 14(1):1-3.
  • Journal of Addictive Diseases 01/2010; 29(1):109-110.
  • Journal of Addictive Diseases 01/2009; 28(1):87-88.
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    ABSTRACT: THe Halikas-Crosby Drug Impairment Rating Scale for Cocaine (HAL DIRS-C) is designed to measure the advers impact of cocaine use upon life functioning over the previous week. The HAL DIRS-C demonstrated excellent split-half and interrater reliability. Internal consistency of the HAL DIRS-C was shown to be high. All items correlated significantly with total score and loaded on a single factor. The HAL DIRS-C correlated significantly with self-reported cocaine use, craving for cocaine, and independent ratings of the severity of addiction. The HAL DIRS-C was found to be sensitive to clinical change across weekly administrations. The scale is brief, east to administer, and both interviewer and client-friendly. our results suggest that the HAL DIRS-C may be useful as a standardized measure of improvement or outcome in clinical research involving the treatment of cocaine abuse.
    Journal of Addictive Diseases 10/2008; 11(2):121-138.
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    ABSTRACT: No abstract available for this article.
    Journal of Addictive Diseases 10/2008; 13(1):119-130.
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    ABSTRACT: One difficulty for methadone maintenance treatment programs is the absence of a simple, analytical method useful for guiding adjustment of methadone dose. Currently, dose adjustment decisions are based upon: documentation of continuing opioid use by qualitative urine drug screens, patient complaints of dose not holding or physiological evidence of opioid withdrawal. Although decisions utilizing clinical parameters are helpful in adjustment of dose, a sizeable number of patients continue to receive inadequate doses. Incorrectly, many clinicians assume that low doses prevent toxicity and favor eventual abstinence. One solution to the question of efficacious dose adjustment would be utilization of repetitive blood sampling for monitoring plasma methadone concentrations to insure they remain within established therapeutic windows. Unfortunately, it is impractical to obtain ongoing blood samples from these patients because of poor venous access and the unpleasantness of frequent phlebotomy. To circumvent these problems, we developed analytical methods useful for estimating plasma methadone concentrations from random, spot urine samples. Over the past several years, we have analyzed approximately 16,000 samples (urine plus plasma) drawn from 200 methadone maintenance patients. These data have allowed generation of methadone dose vs. plasma methadone concentration curves, demonstrating why dose adjustment decisions should be buttressed with objective laboratory data. In addition, these methods are useful for uncovering covert methadone supplementation and diversion. These improvements in clinical care have been accomplished using a computerized, pharmacokinetics program which accounts for compounding effects of urine pH, specific gravity, volume of distribution and gender upon renal methadone excretion. The program allows calculation of total plasma methadone concentrations from concurrent urine measurements, which are within 5-10% of actually meausred values. This system has eliminated the need for venous blood sampling, resulted in optimization of patient doses and helped uncover supplementing or diverting of methadone.
    Journal of Addictive Diseases 10/2008; 13(1):5-26.
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    ABSTRACT: No abstract available for this article.
    Journal of Addictive Diseases 10/2008; 10(1):xi-xii.
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    ABSTRACT: No abstract available for this article.
    Journal of Addictive Diseases 10/2008; 12(1):123-133.
  • Journal of Addictive Diseases 09/2008; 25(4):139-140.
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    ABSTRACT: The objective of this study was to collect data that would provide information about the frequency, attitudes, and consequences of alcohol use in the U.S. Army. A questionnaire was used to assess the frequency of alcohol consumption, attitudes related to the use of alcohol, and adverse consequences experienced with alcohol use. The survey was conducted at Walter Reed Army Medical Center in Washington, D.C. Survey participants included both military employees working at Walter Reed Army Medical Center and military patients. No attempt was made to identify the medical status of the participants. The investigators distributed 1,200 questionnaires. Following distribution, the investigators received 1,010 completed questionnaires, resulting in an 84% return rate. Thirty-four percent of the survey participants (n = 335) were deployed to an area of combat operations. There was a significant difference in binge drinking between military personnel assigned to an area of combat operations and those not assigned to an area of combat operations (p = 0.023). Multiple regression results showed that age, marital status, and deployment status were correlated with four or more drinks at one time (p < 0.001). In other words, binge drinking is more likely to occur among military personnel who are younger, experiencing marital problems, and recently returned from an area of combat operations. Significant differences between the two groups also emerged in terms of other specific consequences associated with consumption. Deployment to an area of combat operations seems to influence consumption patterns, alcohol related attitudes, and behaviors. This could be a consequence of wartime experiences. This study should help guide the clinical screening of alcohol use disorders, which may complicate emotional recovery from traumatic experiences if undetected.
    Journal of Addictive Diseases 06/2008; 27(3):115-21.
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    ABSTRACT: Injection drug use (IDU) accounts for 75% of incident cases of hepatitis C virus (HCV) infection in the developed world. Of those infected with HCV, up to 80% will go on to develop chronic disease. Intervention with effective treatment in eligible subjects will limit the impact of the long-term consequences of infection. The use of combination therapy with pegylated interferon and ribavirin may lead to a cure in up to 80% of treated individuals who carry genotype 2 or 3 isolates. Such individuals account for up to 45% of certain cohorts, such as in the inner city of Vancouver. Historically, many IDUs have not received treatment for HCV infection even if it were medically indicated. Recent data (including our own) suggest that, in the right context, response rates similar to those reported in clinical trials of HCV therapy can be achieved in IDUs, even with ongoing drug use. This is all the more important given that prior infection may protect against re-infection even in the presence of ongoing risk behaviors for HCV transmission. The keys to a successful program appear to be appropriate patient selection as well as the delivery of care within an appropriate setting, preferably with a multidisciplinary team in a way that addresses the issue of addiction and other conditions simultaneously. The development of such programs may be quite complex, but the ultimate benefit (for the treated population and for society as a whole) is certainly worth the effort.
    Journal of Addictive Diseases 02/2008; 27(2):25-35.
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    ABSTRACT: Encouraging results have been demonstrated in large clinical trials in HIV-infected patients taking pegylated interferon and ribavirin for the treatment of hepatitis C virus (HCV) infection. However, only a minority of patients are being treated in the community. Medical providers cite chaotic lifestyles, unstable living situations, and ongoing substance abuse as barriers to these complicated therapies. The stable environment of the correctional system affords a path for intensive education, screening, and treatment of these hard-to-reach patients. Since HIV/HCV coinfected patients are at risk for cirrhosis, end-stage live disease, and hepatocellular carcinoma, incarceration should be viewed as a golden opportunity for important medical interventions.
    Journal of Addictive Diseases 02/2008; 27(2):69-73.
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    ABSTRACT: There has been recent concern about the association between high dose methadone and prolongation of QTc in the electrocardiogram. QTc is the time from the beginning of the QRS complex to the end of the T have as measured on an electrocardiogram and corrected for heart rate. To date, no association has been made between methadone and buprenorphine in commonly used doses and prolonged QTc. Electrocardiograms were performed on groups of methadone (n = 35, mean daily dose +/- standard deviation, 69 +/- 29 mg) and buprenorphine (n = 19, mean daily dose 11 +/- 5 mg) subjects and a group of non-opioid dependent controls (n = 17). Mean QTc did not differ (p = 0.45) between methadone, buprenorphine, or controls. Methadone subjects were significantly (odds ratio of 7.8) more likely to have U waves than buprenorphine and controls combined. Methadone subjects with U waves were maintained on higher (p = 0.004) doses (89 +/- 29 mg/day) than methadone subjects without U waves (60 +/- 24 mg/day). Methadone subjects taking 60 mg and above had higher (p = 0.02) QTc (405 +/- 29 milliseconds) than methadone subjects taking less than 60 mg per day (381 +/- 27 milliseconds). Although an association is thought to exist between high methadone doses and elongated QTc, methadone and buprenorphine, at commonly used daily doses, remain safe agents for opioid substitution therapy.
    Journal of Addictive Diseases 02/2008; 27(3):31-5.