Journal of cardiovascular disease research Impact Factor & Information
Current impact factor: 0.00
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ABSTRACT: Pulmonary artery aneurysm is rare condition in neonates which usually presents with compression on the surrounding vital structures. By definition, an aneurysm is focal dilatation of a blood vessel that involves all three layers of vessel wall. Pulmonary artery aneurysm is defined as focal or fusiform dilatation of the PA beyond its maximum normal caliber. Early recognition and treatment are important for reducing morbidity and preventing mortality. The patients of PAA can be absolutely asymptomatic clinically and may be detected on radiograph or computed tomography or echocardiography. They may present as chest pain, dysnoea, or hemoptysis. It requires multidisciplinary approach for the diagnosis and treatment. It is very important to diagnose and manage the PAA as early as possible due to its high morbidity and mortality. Hence CTA is most important for the accurate evaluation of the PAA for its prompt diagnosis and treatment to reduce the risk of morbidity and mortality. Management of the PAA is surgical as well as medical depending upon the risk factors. The conservative management of PAA is serial follow up and periodic assessment of PAA. This is first case report of congenital aneurysm of pulmonary artery causing extrinsic compression over the left main bronchus leading to collapse. The case was successfully managed with surgical translocation of RPA in front of Ascending aorta, angioplasty of MPA & LPA and repair of the ASD; thereby relieving the compression over the left main bronchus and future complications.Journal of cardiovascular disease research 03/2015; 6(1):31-36. DOI:10.5530/jcdr.2015.1.6
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ABSTRACT: We present a case of combined abdominal and iliac artery aneurysm in 60-year-old male patient who previously had undergone bilateral below knee amputation of both legs due to embolization and subsequent gangrene. Patient was a chronic smoker and was also suffering from hypertension. Computed tomographic (CT) angiogram showed large aneurysm of the infrarenal aorta and right common iliac artery. Surgical intervention in the form of aneurysmorrhapy and aorto-biiliac grafting was done using 20 mm × 10 mm knitted gelatin impregnated bifurcation Dacron graft. The patient recovered well and was discharged after 10 days, post-operative CT angiogram done after 1 month showed difference of contrast enhancement in the anterior and posterior aspects of the graft, probably due to differential flows, turbulence, and stasis and thereby increasing the risk of graft thrombosis.Journal of cardiovascular disease research 11/2014; 5(3). DOI:10.5530/jcdr.2014.3.7
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ABSTRACT: Coronary artery disease (CAD) remains a major global public health problem in 21st century, and it affects as many as 54 million people globally.1 The goals of CAD treatment have several objectives which include relief of symptoms, inhibition of disease progression, prevention of future cardiac events, such as myocardial infarction (MI) and improved survival.2 There is always debate among medical treatment and revascularization which one is superior to each other. Here, we will discuss and try to review in a critical manner the role of revascularization (percutaneous coronary intervention [PCI] versus coronary artery bypass grafting [CABG]) in the management of chronic stable angina in comparison to modern optimal medical therapy (OMT) in the view of recent studies.Journal of cardiovascular disease research 11/2014; 5(3). DOI:10.5530/jcdr.2014.3.3
Article: Bedside Haemo[Show abstract] [Hide abstract]
ABSTRACT: The aim of this study was to compare the performance of nurses and medical staff in using two methods of hemodynamic monitoring in cardiac surgery patients. We designed a double-blind study in which nurses and physicians measured cardiac output and other hemodynamic variables using pulmonary artery catheter thermodilution (PACTD; the ‘gold standard’) and a comparator (continuous cardiac dynamic monitoring [CCDM]-HeartSmart®). Hemodynamic values measured using PACTD and HeartSmart® were comparable between nurses and physicians. In addition, PACTD measurements were in good agreement with those derived from CCDM-HeartSmart®. Specialized Cardiac Intensive Care Unit (CICU) nurses are as competent as any member of the medical staff in measuring hemodynamic measurements using PACTDJournal of cardiovascular disease research 04/2014; 2(2).
- Journal of cardiovascular disease research 03/2014; 2329(2):2.
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ABSTRACT: Many types of cardiac arrhythmias have been noted following acute myocardial infarction. Polymorphic ventricular arrhythmias (polymorphic ventricular tachycardia and ventricular fibrillation) related to an acute myocardial infarction generally strike during the hyperacute phase, are clearly related to ischaemia and are not associated with a long QT interval time. Pause-dependent Torsade de pointes has been reported following acute myocardial infarction and this arrhythmia generally occurs 3–11 days after the onset of acute myocardial infarction and none has been reported during the hyperacute phase. Torsade de pointes – a specific ventricular tachycardia with specific characteristics has been described in hypokalemia, hypomagnesaemia, during Quinidine therapy, and while using phenothiazines and tricyclic antidepressants. It is reported following liquid protein diet, brady-arrhythmias [especially III° AV Block], sick-sinus syndromes. Torsade de pointes either pause-dependent or pause-independent occurring directly as a reperfusion arrhythmia during intravenous thrombolytic therapy has not been reported in the literature to the best of the authors knowledge. Here, an episode of Torsade de pointes as a direct consequence of reperfusion following thrombolytic therapy in a patient of acute myocardial infarction is described.Journal of cardiovascular disease research 03/2014; 4(4). DOI:10.1016/j.jcdr.2014.01.007
Article: Patterns and determinants of cardiovascular drug utilization in coronary care unit patients of a tertiary care hospital. Journal of Cardiovascular Disease Research (2014) 1-8. Published online 06 Feb 2014. Jesso George*, Padmini Devi, Deepak Y. Kamath, Naveen Anthony, Nitin S. Kunnoor, Sandra S. Sanil[Show abstract] [Hide abstract]
ABSTRACT: a b s t r a c t Background: A wide variation exists in the patterns of pharmacotherapy among patients admitted with cardiovascular diseases. Very few studies have evaluated the potential determinants of drug utilization. Our objective was to evaluate the clinical characteristics and patterns of cardiovascular drug utilization among patients in coronary care unit (CCU) and assess the determinants of cardiovascular drug use among patients with coronary artery disease (CAD). Methods: In this retrospective cohort study, the medical records of CCU patients were reviewed independently by two trained physicians over one year. Patients were analyzed as two groups e those with CAD and without CAD. Multivariate logistic regression was done to identify the determinants of cardiovascular drug utilization in the CAD group. Results: Of 574 patients, 65% were males, 57% were <60 years. The five commonly prescribed drug classes were platelet inhibitors (88.7%), statins (76.3%), ACE-inhibitors/Angiotensin receptor blockers (72%), beta-blockers (58%) and heparin (57%). Poly-pharmacy (>5 drugs) was noticed in 71% of patients. A majority of patients had diagnosis of CAD (72.6%). CAD patients received significantly higher median number of drugs and had longer duration of CCU stay (p < 0.0001). Renal dysfunction for ACE-inhibitors [0.18 (0.09e0.36)], ST-elevation myocardial infarction for calcium channel blockers [0.29 (0.09e0.93)] and brady-arrhythmias for beta-blockers [0.3 (0.2e0.7)] were identified as determinants of decreased drug use in CAD group. Conclusion: Predominance of male gender, age <60 and poly-pharmacy was observed in CCU. Antithrombotics, statins, ACE-inhibitors/Angiotensin receptor blockers and beta-blockers were the most frequently prescribed drugs. Clinical co-morbidities (renal dysfunction, arrhythmias) decreased the utilization of ACE-inhibitors, beta-blockers among CAD patients. Copyright � 2013, SciBioIMed.Org, Published by Reed Elsevier India Pvt. Ltd. All rights reserved.Journal of cardiovascular disease research 02/2014;
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