Pharmacognosy Journal Impact Factor & Information
Current impact factor: 1.26
Impact Factor Rankings
Publications in this journal
- Pharmacognosy Journal 12/2015; 7(6):333-338. DOI:10.5530/pj.2015.6.3
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ABSTRACT: Objective: The primary aim of the study was to establish the pharmacognostic standards along with nutritional values on the important medicinal herb Glinus oppositifolius (L.) Aug. DC., commonly known as Parpata in South India. Material and Methods: Pharmacognostical, physicochemical, nutritional evaluation along with the TLC profiling and preliminary phytochemical screening was carried out. Results: Histological study of different parts of the plant revealed the presence of different cellular structures viz. stem showed the presence of multi cellular to unicellular trichomes, collateral vascular bundles, starch grains etc. Mesophyll of the leaves was embedded with starch grains with clustered calcium oxalate and prism shaped crystals. Anomocytic stomata were present on both the epidermis of the leaf. Powder microscopy exhibited multi cellular trichomes, clustered calcium oxalate, fibres etc. Physicochemical and histochemical studies revealed the presence of various secondary metabolites and different minerals within the acceptable limits. Thin layer chromatographic profiling showed different spots suggesting the presence of specific phytoconstituents in different extracts. The plant also revealed good nutritional value with calorific value of about 245 kcal/100g; Vitamin C 112 mg/100 g and higher amount of calcium etc. Conclusion: The results are beneficial to establish the quality control parameters of the plant species and may be served as future reference for the identification and authentication of the genuine crude drug and also provide sufficient data to recognize the use of the plant as dietary supplement.Pharmacognosy Journal 10/2015; 8(1).
- Pharmacognosy Journal 05/2015; 7(4):215-220. DOI:10.5530/pj.2015.4.2
- Pharmacognosy Journal 05/2015; 7(4):242-248. DOI:10.5530/pj.2015.4.6
- Pharmacognosy Journal 05/2015; 7(4):249-253. DOI:10.5530/pj.2015.4.7
- Pharmacognosy Journal 05/2015; 7(4):210-214. DOI:10.5530/pj.2015.4.1
- Pharmacognosy Journal 05/2015; 7(4):236-241. DOI:10.5530/pj.2015.4.5
- Pharmacognosy Journal 05/2015; 7(4):228-235. DOI:10.5530/pj.2015.4.4
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ABSTRACT: Introduction: The present study was designed to investigate the in vitro antioxidant and macromolecule damage protective effects of Asparagus racemosus water (AWE) and methanolic (AME) fractions of roots. Methods: The in vitro antioxidant activity of AWE/AME was estimated by free radical scavenging assays. The DNA damage of HT29 and C2C12 cells was analyzed by comet assay. The plasmid DNA damage and protein oxidation were carried out by agarose gel electrophoresis and SDS-PAGE analysis respectively, where as lipid peroxidation was performed by TBARS assay. Results: Both the extracts showed scavenging activity with IC50 values of 417.4 ± 19.5 / 298 ± 13.5, 381 ± 18.2 / 235 ± 11.9, 54.8 ± 2.95 / 31.6 ± 1.52, 28.9 ± 1.73 / 19.7 ± 1.55 μg/mL for DPPH, metal chelating, ABTS and Nitric oxide scavenging activities respectively. Similarly the methanolic extract showed more potent reducing power and total antioxidant activities over water fraction. The AME showed 56.8% and 41.2% protection against H2O2 (Hydrogen peroxide) induced DNA damage of HT29 human colon cells and C2C12 murine myoblasts. The extract also showed protection against H2O2 induced plasmid DNA damge, AAPH induced protein oxidation of bovine serum albumin (BSA) and lipid peroxidation of rat hepatic tissue. Conclusion: Over all this study showed remarkable antioxidant and macromolecule damage protective effects of A.racemosus. The observed biological properties may be attributed to the high content phenols and flavonoids in the methanolic extract A. racemosus over water extract.Pharmacognosy Journal 05/2015; 7(3).
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