International Journal of PharmTech Research
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Publications in this journal
- International Journal of PharmTech Research 02/2014; 6(1):97-116.
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ABSTRACT: Abstract : The aim of the present work is to perform physicochemical analysis, phytochemical screening and antimicrobial activity of Morinda tinctoria fruits at different maturity stages. Physicochemical parameters were studied as per WHO recommended guidelines for standardization. The fruits were extracted by different solvents and tested for preliminary phytochemical screening and antimicrobial activity against selected pathogenic microorganisms. Physicochemical parameters such as ash values, moisture content and extractive values were determined. The results of phytochemical analysis revealed the presence of various secondary metabolites. Antimicrobial activity revealed that different extracts of M. tinctoria fruits exhibited inhibitory effects against the pathogens. In the present study, S. typhi (16 mm) and K. pneumoniae (18 mm) were inhibited by ethanol and methanol extract of mature fruit extracts. The result of physicochemical analysis is useful in developing standards for sample identity and purity of M. tinctoria fruits. The different extracts of M. tinctoria showed the presence of various secondary metabolites and the extracts were found to be effective against the tested microorganisms. It can be concluded that the fruits of M. tinctoria would be helpful in the development of phyto-medicine against microbial infections.International Journal of PharmTech Research 01/2014; 6(2):834-841.
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Bentham Science Publishers