Journal of Clinical and Diagnostic Research Impact Factor & Information

Current impact factor: 0.23

Impact Factor Rankings

Additional details

5-year impact 0.00
Cited half-life 0.00
Immediacy index 0.00
Eigenfactor 0.00
Article influence 0.00
ISSN 0973-709X

Publications in this journal

  • Journal of Clinical and Diagnostic Research 11/2015; 9(12):XD01-03. DOI:10.7860/JCDR/2015/14561.6876
  • [Show abstract] [Hide abstract]
    ABSTRACT: Introduction: Diabetes mellitus and its related ocular complication like diabetic retinopathy (DR) are showing increased prevalence in India, but the magnitude of presence and progression of DR in central rural population and its relation to certain variables requires further exploration. Aim: To study the demographic profile on diabetic retinopathy and the association between different risk factors of diabetic retinopathy with its onset and severity. Materials and methods: A cross-sectional study was carried out on patients suffering from diabetes mellitus (n=100) admitted to AVBRH, Sawangi (Meghe) in a duration of 2 months from April to June 2014. Snellen's chart, slit lamp, and indirect ophthalmoscope were used for ocular examination of all patients. Comprehensive examination was used for risk factor assessment. Statistical analysis: All data was entered into the proforma. Chi-square test, Student's unpaired t-test and one way ANOVA using SPSS 17.0 and Graph Pad Prism 5.0. (p<0.05 was considered significant). Results: The study showed that among all the diabetics (mean age 56.4+11.2 years), 68% were males and 97% type 2 diabetics. This study showed statistically significant association between serum triglyceride (p=0.0003), duration since diagnosis of diabetes mellitus (p=0.0006), serum total cholesterol (p=0.0021), FBG (p=0.003), serum HDL (p=0.012) and hypertension (p=0.045) with presence of diabetic retinopathy. The study also revealed that serum triglycerides (p=0.001), serum total cholesterol (p=0.006), BMI (p=0.04) and duration of diabetes (p=0.04) are the only factors which showed significant association with the severity of diabetic retinopathy. Conclusion: Effective screening strategies for early detection of both diabetes and diabetic retinopathy should be formulated especially for the rural population which is not aware about the various complications of diabetes and their final outcomes. Diabetics should follow proper guidelines to prevent or delay progression of DR.
    Journal of Clinical and Diagnostic Research 11/2015; 9(10). DOI:10.7860/JCDR/2015/12785.6689
  • [Show abstract] [Hide abstract]
    ABSTRACT: Introduction: Urinary tract infections as a result of Candida species are becoming increasingly common in hospital settings. The association is higher in patients with prolonged urinary catheterization and also various pre-disposing factors. Aim: This study was done to look into the significance of candiduria in the catheterized patients and to perform microbial catheterization of yeast and biofilm detection by tube method to guide treatment protocol. Materials and methods: This is a prospective study. One hundred urine samples were collected over a period of 3 months. Specimens included were those of patients presenting with nosocomial Urinary tract infection (UTI) after 72 hours of hospitalization. The urine samples obtained were immediately processed in microbiology laboratory by semi-quantitative method as per standard protocol. All yeast isolates were stored for further microbial characterization. Biofilm production was detected by tube method. Results: In the present study we observed that out of 100 samples obtained from catheterized patients presenting with nosocomial UTI 26% were caused by Candida species. Among the 26 Candida isolates 16 (61.53%) were non albicans Candida and 10(38.47%) were Candida albicans. Out 26 Candida isolates, 14(53.84%) of the candida isolates were found to produce biofilm. Biofilm production was found to occur more frequently among non albicans Candida 10(62.5%) than Candida albicans 4(40.0%). Conclusion: The present study reiterates the presence of candiduria in catheterized patients. Non-albicans candida speices are replacing candida albicans as the predominant pathogen for nosocomial UTI. It was also observed that Biofilm formation is seen more frequently with non albicans candida species than with Candida albicans.
    Journal of Clinical and Diagnostic Research 11/2015; 9(10). DOI:10.7860/JCDR/2015/13910.6690
  • [Show abstract] [Hide abstract]
    ABSTRACT: Introduction: Acne is the most common disease of skin affecting adolescents, which can have a significant psychological impact leading to anxiety and depression. Aims: Study was undertaken to see the impact of acne on the Quality of life. Materials and methods: The study was conducted from March 2012 to February 2013, in the age group 14-25, using a validated self-administered questionnaire The questions were evaluated using 4 point Likert scale (0-3). Statistical analysis: Statistical calculations were done using Excel 2010 and Statgraphics Centurion XVI.I. Results: Among 869 participants, 608(69.97%) had acne while 261 (30.03%) had no acne. Of acne sufferers 43.75% were males and 56.25% were females with maximum 67.93% in the age group 18-21. Of Non-acne participants 57.09% considered acne as a problem and 54.02% were disturbed by the idea of having acne. Study showed p-values<0.05 indicating statistically significant non-zero correlations at 95.0% confidence level. Conclusion: The quality of life scale of acne varies according to individual perception and differs from population to population. Questionnaire evaluation is a useful tool, but cannot replace proper psychological assessment.
    Journal of Clinical and Diagnostic Research 11/2015; 9(10). DOI:10.7860/JCDR/2015/14709.6683
  • [Show abstract] [Hide abstract]
    ABSTRACT: Introduction: The global prevalence of chronic kidney disease (CKD) is estimated to be 8-16%. Studies have shown that the increased mortality in patients with CKD is due to anemia that leads to cardiovascular disease (CVD), also known as "Cardio renal anemia syndrome". The present study was undertaken to look into the laboratory profiles of end stage renal disease (ESRD) patients. Aim: To study the laboratory profiles of End stage renal disease (ESRD) patients coming for hemodialysis. Materials and methods: The study was a retrospective, cross- sectional study done by collecting data from the medical case records of all patients during a period of one year from January 1(st) 2014 to December 31(st) 2014. Records of a total of 140 patients who underwent hemodialysis during this period were taken. The laboratory profiles that was recorded included haemoglobin, serum sodium, potassium, chloride, fasting glucose, calcium and phosphorus. Results: The mean age of the subjects was 53.5±14.5 yrs. All the patients had moderate anaemia. There was a significant difference in the mean systolic and diastolic blood pressure, serum creatinine and serum urea values between males and females. The mean serum calcium levels were low. Conclusion: The present study is the first such study in this rural area and shows evidence of a relatively young population with ESRD having moderate anaemia and hypertension. There is evidence of hypocalcaemia and serum phosphorus is on the higher end of the normal range. These findings are usually associated with a higher risk of mortality. With the explosion of diabetes and hypertension in India, chronic kidney disease should be diagnosed and managed as early as possible if not prevented.
    Journal of Clinical and Diagnostic Research 11/2015; 9(10). DOI:10.7860/JCDR/2015/14928.6697

  • Journal of Clinical and Diagnostic Research 11/2015; 9(10). DOI:10.7860/JCDR/2015/14951.6597
  • [Show abstract] [Hide abstract]
    ABSTRACT: Diagnosis of non accidental injury needs careful history elicitation, proper examination and thorough workup including blood investigation and radiological assessment to avoid misdiagnosis or under diagnosis. Correct diagnosis and reporting would avoid possible similar incidents in the future. Four-year-old female child brought to our hospital by her mother with apparent history of fall from height. Following detailed examination and radiological assessment we suspected of child abuse. Child had multiple fractures in different stages of healing which included bilateral intertrochanteric fractures. Child was operated for bilateral intertrochanteric fractures which appeared relatively fresh compared to other old malunited fractures with open reduction and fixation with titanium elastic nailing and was immobilized by hip spica. Two months postoperatively, there was complete radiological union of fractures and child was being counseled by child psychologist.
    Journal of Clinical and Diagnostic Research 11/2015; 9(10). DOI:10.7860/JCDR/2015/16033.6603
  • [Show abstract] [Hide abstract]
    ABSTRACT: Background: The standard of care for patients who undergo an inadvertent hysterectomy for invasive cervical carcinoma is not well established. Aim: The aim of this study was to evaluate the role of induction chemotherapy followed by external beam radiotherapy and brachytherapy in patients who had an inadequate hysterectomy for carcinoma of the cervix. Materials and methods: Patients with history of inadequate hysterectomy with no residual disease at presentation to our outpatients department of Radiotherapy and registered between October 2011 to June 2014 were retrospectively analyzed. Most of these patients had received three cycles of induction chemotherapy using Paclitaxel and Carboplatin regime. Thereafter, these patients had received external beam radiotherapy and vaginal brachytherapy. The primary end points were overall survival and disease-free survival. Survival analysis was done using Kaplan-Meier method and the differences in survival rates were compared using log-rank test. Results: A total of 34 patients were eligible for the study. Overall survival and Disease-free survival at 3-years were 70% and 68%. Patients who had Taxane-based chemotherapy had significantly better survival outcomes than their counterparts. Vaginal vault boost with brachytherapy had a significant impact on prognosis of these patients. Conclusion: Induction chemotherapy using Paclitaxel and Carboplatin followed by external beam radiotherapy and brachytherapy is a good treatment option for patients of carcinoma of the cervix who have undergone inadvertent hysterectomy.
    Journal of Clinical and Diagnostic Research 11/2015; 9(10). DOI:10.7860/JCDR/2015/15739.6640
  • [Show abstract] [Hide abstract]
    ABSTRACT: Schwanommas arising from cervical sympathetic chain are tumours that are rare in occurrence. These lesions are usually difficult to differentiate from a vagal schwanomma and a carotid body tumour during the initial workup. In this report, a rarely seen huge cervical sympathetic chain schwanomma case with partial Horner’s syndrome is being presented in detail, which to our known knowledge, is one of the few cases reported in literature. © 2007-2015, Journal of Clinical and Diagnostic Research, India. All Rights Reserved.
    Journal of Clinical and Diagnostic Research 11/2015; 9(10). DOI:10.7860/JCDR/2015/14897.6693
  • [Show abstract] [Hide abstract]
    ABSTRACT: Background: For fluoridated toothpaste to be effective in controlling dental caries, an adequate concentration of soluble fluoride must be available in the oral cavity. Aim: To determine the total and free fluoride concentration in various brands of toothpaste marketed in India. Materials and methods: Three samples of 12 different toothpastes were purchased from supermarkets in Mysore city, Karnataka, India. Toothpastes were analysed in duplicate using a fluoride ion-specific electrode. The concentration of total fluoride (TF) and total soluble fluoride (TSF) were determined. Results: Measured TF was consistent with that declared by the manufacturer in five products. Four toothpastes showed lower TF and two higher TF than declared. Most toothpastes exhibited TSF concentrations similar to the TF content except four samples that displayed considerably lower TSF than TF. Conclusion: The measurement of total and free fluoride concentrations of toothpastes available in India showed inhomogenities. Therefore there is a need for stringent regulatory control measures for the determination of fluoride content in toothpastes in developing country like India.
    Journal of Clinical and Diagnostic Research 11/2015; 9(10). DOI:10.7860/JCDR/2015/13382.6578
  • [Show abstract] [Hide abstract]
    ABSTRACT: Pseudoepitheliomatous, keratotic and micaceous balanitis (KPMB) is a rare condition affecting glans penis of elderly men. It is characterized by thick hyperkeratotic plaque with micaceous scaling often leading to phimosis. Here we are reporting a rare case of pseudoepitheliomatous, keratotic, and micaceous balanitis in 50-year-old man who has undergone circumcision 16 years back. Till date only a handful cases have been reported in world literature.
    Journal of Clinical and Diagnostic Research 11/2015; 9(10). DOI:10.7860/JCDR/2015/15663.6601
  • [Show abstract] [Hide abstract]
    ABSTRACT: Introduction: Optimal treatment strategy in children with advance stage Hodgkin Lymphoma (HL) still remains controversial. Aim: To evaluate the clinical profile and the efficacy of chemotherapy (CT) as a treatment modality in paediatric HL. Material and Methods: Retrospective case record evaluation of paediatric HL cases over 5 years (October 2005 to October 2010) period. Results: Thirty five cases (31 boys) with a median age of eight years were studied. 24 cases were <10-year-old, and 23 had late stage disease (stage III to IV). B-symptoms were present in 60%, bulky mediastinal disease in 25.7%, and spleen involvement in 60% cases. None had bone marrow involvement. Most common histological type was nodular sclerosis (28.6%). Most cases received ABVD/COPP or ABVD regimen. Two cases needed BEACOPP due to progressive disease, and 4 needed low-dose involved field radiotherapy (RT). At a mean (SD) extended event-free follow-up of 42.7(±17.1) months, four cases relapsed (one was lost to follow-up, and three were treated with chemotherapy and low-dose involved field RT). None died due to the disease. Conclusion: Present study found systemic CT alone to be an effective therapy in childhood Hodgkin lymphoma. However, a small sample in present study limits the generalisability of these findings. The findings needs to be replicated in larger population, preferably randomized clinical trials, before any firm conclusion can be made.
    Journal of Clinical and Diagnostic Research 11/2015; 9(11):SC25 - SC30. DOI:10.7860/JCDR/2015/14876.6845
  • [Show abstract] [Hide abstract]
    ABSTRACT: Introduction: Hypertension is a major public health problem in India and worldwide. Since hypertension is often asymptomatic, it commonly remains undetected, leading to serious complications if untreated. Hypertension is one of the leading causes of end stage renal disease. It doubles the risk of developing coronary artery disease, increases the risk of congestive heart failure by four folds and that of cerebrovascular disease and stroke by seven folds. Hypertension is directly responsible for 57% of all stroke deaths and 42% of coronary heart disease deaths in India. Aim: To identify prevalence and risk factors for hypertension in a semi urban population of Mangalore, who participated in Boloor Diabetes Study (BDS-II). Materials and Methods: This cross-sectional study was conducted on 551 subjects aged ≥ 20 years who were randomly selected. Hypertension was diagnosed and classifid according to Joint National Committee 7 (JNC) criteria. Blood pressure was measured by a doctor using calibrated sphygmomanometer. Anthropometric measurements, lipid and glucose estimations were done for all subjects. Statistical analysis was done using Chi-square test and student’s t-test (unpaired). Multivariate logistic regression analysis was done using hypertension as dependent variable and the various risk factors as independent variables. results: Overall prevalence of hypertension in the community was 41% (227/551) (40.9% in men, 41.3% in women). Prehypertension was found in 40% (223/551) (45.4% in men, 38.1% in women), and only 18.3% (101/551) had normal blood pressure. Stage I hypertension was seen in 29.7% (164/551) (28.9% in men, 30.1% in women). Stage II hypertension was seen in 11.4% (63/551) (12% in men, 11% in women). Age, obesity, diabetes, serum cholesterol and serum triglycerides were strongly associated with hypertension. Only 46% (254/551) of the hypertensive subjects were aware that they were hypertensive. conclusion: Prevalence of hypertension was high in this population. Nearly 54% were unaware of their hypertensive status. Prevalence increased with age, obesity, diabetic status and dyslipidemia. Nearly half of subjects were prehypertensives. This study highlights the need for regular screening coupled with educational programmes to detect, improve awareness and optimally treat hypertension in the community to reduce cardiovascular and renal complications.
    Journal of Clinical and Diagnostic Research 11/2015; 9(11):IC01-IC04.