Journal of Clinical and Diagnostic Research Impact Factor & Information

Journal description

Current impact factor: 0.23

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5-year impact 0.00
Cited half-life 0.00
Immediacy index 0.00
Eigenfactor 0.00
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ISSN 0973-709X

Publications in this journal

  • Journal of Clinical and Diagnostic Research 12/2015;
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    ABSTRACT: ABST RACT Introduction: Pre-eclampsia is an obstetrics problem that affects multiple systemic functions and leads to the increased maternal and fetal morbidity and mortality. The objective of the study was to evaluate the plasma levels of Xanthine oxidase (XO) activity, uric acid and Nitric oxide (NO) levels in women with pre-eclampsia and normal pregnancy during antenatal and postpartum period. Materials and Methods: A case control study was conducted in women with normal pregnancy (n=50) and pre-eclampsia (n=50) before and after delivery. XO activity, uric acid and NO levels were determined from samples at 30-39 weeks of gestation. The current study was conducted in association with Obstetrics and Gynecology Department of R.L.Jalappa Hospital and Research Center. The blood samples were analysed for assay of XO, uric acid and NO. The results were analysed by using SPSS software version 2013. P-value < 0.05 was considered as statistically significant. R esults: The plasma XO activity was elevated (p<0.001) in the pre-eclampsia compared to normotensive pregnant women before delivery and decreased after delivery (p<0.001) significantly. Uric acid level showed a significant increase in pre-eclampsia when compared to the control before delivery (p<0.001) however values were non-significant after delivery. Conclusion: Placenta plays a key role in the pathophysiology of pre-eclampsia. Placenta removal leads to decrease trend of xanthine oxidase activity, uric acid and elevation of Nitric oxide as reversible changes in pre-eclampsia patients within 48 hours after delivery.
    Journal of Clinical and Diagnostic Research 10/2015; 9(10):01-03. DOI:10.7860/JCDR/2015/15114.6607
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    ABSTRACT: Herpes zoster is a clinical manifestation which results from reactivation of latent VZV (Varicella zoster virus) present in the sensory root ganglia. Disseminated herpes zoster has been reported in immune-compromised patients such as patient on cancer chemotherapy, HIV (Human immune deficiency virus) infection, systemic corticosteroid therapy. However, we report a case of disseminated herpes zoster infection in an uncontrolled diabetic patient. A brief review of literature on this topic has been bestowed.
    Journal of Clinical and Diagnostic Research 09/2015; 9(7). DOI:10.7860/JCDR/2015/12242.6240
  • Journal of Clinical and Diagnostic Research 09/2015; 9(7). DOI:10.7860/JCDR/2015/14402.6256
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    ABSTRACT: Children with uncorrected cyanotic congenital heart diseases can present for non cardiac surgeries. They pose several challenges to the Anaesthesiologist, especially when they are posted for emergency surgery, due to the complex haemodynamic changes secondary to the heart disease. Pentalogy of Fallot (POF) is a rare form of congenital heart disease characterized by the association of Tetralogy of Fallot (TOF) with an atrial septal defect (ASD). TOF is the leading cause of intracardiac right to left shunt and is the commonest type of cyanotic congenital heart disease to cause a brain abscess. Children with POF presenting with brain abscess pose several challenges to the anaesthesiologist due to the altered haemodynamics and warrant a meticulous anaesthetic plan. There are very few case reports of Anaesthesia management of a child with Pentalogy of Fallot (POF) presenting for non cardiac surgery. We report the anaesthetic management of a rare case of a 5-year-old child with uncorrected POF, who presented to our Superspeciality hospital with a brain abscess and underwent an emergency craniotomy with drainage of the brain abscess successfully.
    Journal of Clinical and Diagnostic Research 09/2015; 9(7). DOI:10.7860/JCDR/2015/13650.6149
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    ABSTRACT: Aim: To compare the effect of umbilical cord care with Povidine Iodine- Spirit on umbilical infection in early neonatal period. Materials and methods: Prospective double blinded randomized controlled study was undertaken to evaluate the effect of daily cleansing of the umbilical cord of term infants with Spirit (Alcohol) -Povidine Iodine combination). This was also compared to the retrospective data obtained for the prevailing practice of keeping the umbilical cord dry. Results: 1518 infants were included in the study. (462 in the "cord care group", 496 in the "water" placebo group, & 560 in "Dry" retrospective group). There was an overall reduction in the clinically screened and evaluated "umbilical infection" in the Povidine -Iodine group. This was attributable to a greater reduction in the mixed bacterial (Colonizer/ commensals) isolates. The Relative Risk for Staph. aureus was lesser when the cord was kept dry (RR 0.6, p<0.01) and sterile water (Placebo) group (RR 0.7, p<0.01). Conclusion: Avoiding the antiseptic cleansing increased the RR for commensal / mixed bacterial over growth that would probably facilitate umbilical cord separation.
    Journal of Clinical and Diagnostic Research 09/2015; 9(7). DOI:10.7860/JCDR/2015/13562.6162
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    ABSTRACT: Emphysematous cholecystitis (EC) is a life threatening condition characterized by gangrene of the gallbladder due to an infection with gas-forming organisms. It is more common in elderly men and has been associated with systemic disease, especially diabetes and vascular disease. Computed tomography is the most important and accurate imaging modality for the diagnosis of EC. EC should be thought of when the radiographic presence of gas is detected within the gallbladder wall or lumen. Emergency surgical intervention and antibiotic treatment for the gas-forming organism should be initiated after the diagnosis of the EC. Here, we present the imaging and pathologic findings of a 24-year-old male with EC without any predisposing factors, successfully treated with laparoscopic cholecystectomy.
    Journal of Clinical and Diagnostic Research 09/2015; 9(7). DOI:10.7860/JCDR/2015/13300.6160
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    ABSTRACT: Suction cap-induced palatal perforation is uncommon today. In the surgical management of such a complication, the surgeon should consider the large bony defect hidden behind the small slit in the palatal mucosa. In this article a case is presented,in which a combination of anteriorly based inferior turbinate flap and posteriorly based palatal submucosal flap solved the problem properly. The advantages of this technique are two-layer closure and predictability of the technique.
    Journal of Clinical and Diagnostic Research 09/2015; 9(7). DOI:10.7860/JCDR/2015/13838.6209
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    ABSTRACT: Dengue is the most common and widespread arthropod borne arboviral infection in the world today. Recent observations indicate that the clinical profile of dengue fever is changing with neurological manifestations being reported more frequently. A 50-year-old male patient was admitted with fever and thrombocytopenia. He was diagnosed as dengue fever with positive IgM dengue serology. Patient was managed medically in the ward for seven days and observed for any complications. Fever subsided since third day of admission and platelet count started to improve; he had no complication of dengue fever and was discharged in stable condition. However, patient again came back to emergency with two episodes of generalized tonic clonic seizures followed by altered sensorium. Emergency NCCT head and later MRI brain revealed bilateral subdural effusion. Patient was managed with antiepileptic drugs and anti-oedema measures were taken. Patient showed improvement in sensorium after 48 hours of admission. Later after six weeks NCCT and MRI brain revealed complete resolution of subdural effusion.
    Journal of Clinical and Diagnostic Research 09/2015; 9(7). DOI:10.7860/JCDR/2015/13346.6161
  • Journal of Clinical and Diagnostic Research 09/2015; 9(8):xc05-xc08.