The Indian Journal of Medical Research (INDIAN J MED RES)

Publisher: Indian Council of Medical Research, Medknow Publications

Journal description

The Indian Journal of Medical Research (IJMR) is one of the oldest medical Journals not only in India, but probably in Asia, as it started in the year 1913. The Journal was started as a quarterly (4 issues/year) in 1913 and made bimonthly (6 issues/year) in 1958. It was made monthly (12 issues/year) in the year 1964. The Journal is being indexed and abstracted by all major global current awareness and alerting services (Annexure). The Indian Journal of Medical Research is published monthly, in two volumes and 12 issues per year. The IJMR publishes peer reviewed quality biomedical research in the form of original research articles, review articles, short papers and short notes. Special issues and supplements are published in addition to the regular issues.

Current impact factor: 1.66

Impact Factor Rankings

2015 Impact Factor Available summer 2015
2013 / 2014 Impact Factor 1.661
2012 Impact Factor 2.061
2011 Impact Factor 1.837
2010 Impact Factor 1.826
2009 Impact Factor 1.516
2008 Impact Factor 1.883
2007 Impact Factor 1.67
2006 Impact Factor 1.224
2005 Impact Factor 0.869
2004 Impact Factor 0.6
2003 Impact Factor 0.452
2002 Impact Factor 0.445
2001 Impact Factor 0.34
2000 Impact Factor 0.383
1999 Impact Factor 0.365
1998 Impact Factor 0.4
1997 Impact Factor 0.318
1996 Impact Factor 0.251
1995 Impact Factor 0.198

Impact factor over time

Impact factor

Additional details

5-year impact 2.31
Cited half-life 6.50
Immediacy index 0.33
Eigenfactor 0.01
Article influence 0.58
Website Indian Journal of Medical Research website
Other titles Indian journal of medical research (New Delhi, India: 1994)
ISSN 0971-5916
OCLC 59369085
Material type Periodical, Internet resource
Document type Internet Resource, Journal / Magazine / Newspaper

Publisher details

Medknow Publications

  • Pre-print
    • Author can archive a pre-print version
  • Post-print
    • Author can archive a post-print version
  • Conditions
    • Non-commercial
    • Publisher's version/PDF may be used
    • Creative Commons Attribution Non-Commercial Share Alike License
    • Published source must be acknowledged
    • All titles are open access journals
  • Classification
    ​ green

Publications in this journal

  • [Show abstract] [Hide abstract]
    ABSTRACT: Background & objectives: Severe Acute Respiratory Infections (SARI) are one of the leading causes of death among children worldwide. As different respiratory viruses exhibit similar symptoms, simultaneous detection of these viruses in a single reaction mixture can save time and cost. Present study was done in a tertiary care children's hospital for rapid identification of viruses causing SARI among children ≤ 5 years of age using multiplex real time PCR kit. Methods: Throat swabs were collected and processed for extraction of nucleic acid using automated extraction system and multiplex real time RT-PCR done using Fast Track Diagnostics Respiratory pathogens 21 kit taking three hours to process and report a sample. Results: The overall positivity for viruses in the study was found to be 72.90% with a co-infection rate of 19.46%. Human Metapneumovirus (HMPV) was the predominant virus detected in 25.74% children followed by Influenza A(H1N1)pdm09, Human Rhinovirus (HRV) and Human Adenovirus (HAdV) in 19.85%, 11.03%, 8.82% children respectively. The HMPV was at its peak in the month of February, 2013, HAdV showed two peaks in March – April, 2012 and November, 2012 – March, 2013 while HRV was detected throughout the year. Interpretations & conclusions: Multiplex real time PCR helped in rapid identification of viruses. Seventeen viruses were detected in SARI cases with overall positivity of 72.9%, HMPV was the most predominant one. However for better clinico virological correlation, studies are required with complete work up of all the etiological agents, clinical profile of patients and treatment outcome.
    The Indian Journal of Medical Research 05/2015; Accepted.
  • The Indian Journal of Medical Research 04/2015; 141(February 2015):242-244.
  • The Indian Journal of Medical Research 03/2015;
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    ABSTRACT: Ciprofloxacin is commonly used in clinical practice for the treatment of recurrent urinary tract infections caused by Escherichia coli. However, very often these recurrent infections are due to a failure in a complete eradication of the microorganisms colonizing the urinary tract, especially in catheterized patients. To enhance the bactericidal activity of ciprofloxacin against biofilm-forming uropathogenic E. coli (UPECs), we examined its effect in combination with two pentacyclic triterpenes - asiatic and ursolic acids. The anti-biofilm activity of ciprofloxacin and pentacyclic triterpenes - asiatic acid (AA) and ursolic acid (UA), as well as their synergistic effect were tested on two types of surfaces - polystyrene microtiter plates and silicone catheters. It was investigated using the time-killing and biofilm assays. a0 nti-biofilm activity of ciprofloxacin was not observed on microtiter plates or on the catheters. Ciprofloxacin combined with ursolic acid inhibited the biofilm formation on microtitre plates. This mixture, however, did not express such a strong activity against the synthesis of biofilm on the surface of catheters. Ciprofloxacin combined with asiatic acid had very weak inhibiting effect on the synthesis of biofilm mass on microtitre plates as well as on the catheters. Despite this, both mixtures - ciprofloxacin and asiatic acid, as well as ciprofloxacin and ursolic acid, exhibited strong and significant impact on the eradication of mature biofilm (P < 0.05). Although ciprofloxacin is recommended in the treatment of urinary tract infections caused by UPECs, but its efficacy is arguable. Subinhibitory concentrations of ciprofloxacin did not inhibit the formation of biofilm. Pentacyclic triterpenes used in combination with ciprofloxacin enhanced its anti-biofilm effectiveness. However, this anti-biofilm activity was found to depend on the type of surface on which biofilm was formed.
    The Indian Journal of Medical Research 03/2015; 141(3):343-53.
  • The Indian Journal of Medical Research 03/2015; 141(3):269-70.
  • The Indian Journal of Medical Research 03/2015; 141(3):371-2.
  • The Indian Journal of Medical Research 03/2015; 141(3):271-3.
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    ABSTRACT: Early identification of bacterial infection in patients with fever is important for prompt treatment. However, the available parameters such as C-reactive protein (CRP) and leukocyte counts are not very specific. This study was aimed to assess the diagnostic value of procalcitonin (PCT), CRP, interleukin-6 (IL-6) and serum amyloid A (SAA) for bacterial infection in febrile patients. Serum samples were collected from febrile patients between January and December 2012 and processed for blood cultures. PCT, IL-6, CRP and SAA levels were measured. The patients were divided into three groups according to the final diagnosis: bacteraemia group (group1), bacterial infection with negative blood culture (group 2) and non-bacterial infection group (group 3). There were significant (P<0.05) difference in the levels of PCT, CRP, IL-6 and SAA among the three groups. The PCT levels of patients with g0 ram-positive bacterial infections were lower than g0 ram-negative bacterial infections (0.53 vs 2.13, P < 0.01). The best cut-off value to detect bacterial infections was 0.26 ng/ml for PCT. PCT, CRP, IL-6 and SAA had areas under the curve of 0.804, 0.693, 0.658 and 0.687, respectively. Our results showed PCT as a valuable marker of bacterial infections in febrile patients. PCT was superior to CRP, IL-6 or SAA in the early identification of bacterial infection. More prospective and large scale studies are warranted to confirm these findings.
    The Indian Journal of Medical Research 03/2015; 141(3):315-21.
  • The Indian Journal of Medical Research 03/2015; 141(3):361-3.
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    ABSTRACT: Background and objectives: Tribal people often depend on herbal medicines and the traditional Knowledge Practitioners (TKPs) serve as their healthcare service providers. This study was an attempt to document the use of medicinal plants by the Nicobarese of Nancowry group of Islands. Materials and Methods: Field survey was conducted in all the five inhabited Islands of the Nancowry group of Islands. All the TKPs were interviewed with a questionnaire-guided ethnomedicinal survey protocol. Voucher specimens of all the cited plants (botanic species) were collected and a community biodiversity register of Nicobarese of Nancowry was prepared. Results: A total of 77 TKPs were identified, who together were using 132 medicinal plant species belonging to 113 genera and 62 families. The TKPs were treating a total of 43 ailments. Seven endemic and 3 rare plant species were recorded. The most common plant part used was leaves. Remedies were usually prepared using water as the excipient. The medicinal plant preparations are administered through oral, topical and others routes. The information collected from the TKPs were collated in the form of Community Biodiversity Registers. Interpretation and conclusions: Traditional knowledge of the remedies is passed down from the older generation to the younger through narrations and no written documents are maintained. Medicinal plants still play a pivotal role in the healthcare of the Nicobarese tribe of Nancowry group of Islands. Efforts to document at the medicinal plant species and the formulations are necessary to prevent the loss of the precious knowledge due to a loss of the oral tradition or other reasons.
    The Indian Journal of Medical Research 03/2015;
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    ABSTRACT: Presence of psychological morbidity in medical undergraduate students has been reported from various countries across the world. Indian studies to document this burden are very few. Therefore, the presence of depression, anxiety and stress among medical undergraduate students was assessed using a previously validated and standardized instrument, Depression Anxiety Stress Scale (DASS 42) and the associations with their socio-demographic and personal characteristics were identified. In a cross-sectional survey, a self-administered, pre-designed, pre-tested anonymous questionnaire including DASS 42 was used to collect information on basic socio-demographic (age, gender, semester) and personal characteristics (alcohol and tobacco use, academic performance). All students present on the day of survey were contacted for participation after obtaining informed written consent. Scores for each of the respondents over each of the sub-scales (Depression, Anxiety and Stress) were calculated as per the severity-rating index. More than half of the respondents were affected by depression (51.3%), anxiety (66.9%) and stress (53%). Morbidity was found to be more in 5 th semester students rather than students of 2 nd semester. Females reported higher score as compared to their male counterparts. Perception of self assessment in academics was strongly associated with the higher score. A substantial proportion of medical undergraduate students was found to be depressed, anxious and stressed revealing a neglected area of the students' psychology requiring urgent attention. Student counselling services need to be made available and accessible to curb this morbidity.
    The Indian Journal of Medical Research 03/2015; 141(3):354-7.
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    ABSTRACT: During the last century, vitamin A has evolved from its classical role as a fat-soluble vitamin and attained the status of para-/autocrine hormone. Besides its well-established role in embryogenesis, growth and development, reproduction and vision, vitamin A has also been implicated in several other physiological processes. Emerging experimental evidences emphasize adipose tissue as an active endocrine organ with great propensity to continuous growth (throughout life). Due to various genetic and lifestyle factors, excess energy accumulates in adipose tissue as fat, resulting in obesity and other complications such as type 2 diabetes, hypertension, and cardiovascular disease. Recent in vitro and in vivo studies have shed light on vitamin A metabolites; retinaldehyde and retinoic acid and participation of their pathway proteins in the regulation of adipose tissue metabolism and thus, obesity. In this context, we discuss here some of our important findings, which establish the role of vitamin A (supplementation) in obesity and its associated disorders by employing an obese rat model; WNIN/Ob strain.
    The Indian Journal of Medical Research 03/2015; 141(3):275-84.
  • The Indian Journal of Medical Research 03/2015; 141(3):358-9.
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    ABSTRACT: Pleural effusion is a common occurrence in patients with late-stage chronic kidney disease (CKD). In developing countries, many effusions remain undiagnosed after pleural fluid analysis (PFA) and patients are empirically treated with antitubercular therapy. The aim of this study was to evaluate the role of adenosine deaminase (ADA), nucleic acid amplification tests (NAAT) and medical thoracoscopy in distinguishing tubercular and non-tubercular aetiologies in exudative pleural effusions complicating CKD. Consecutive stage 4 and 5 CKD patients with pleural effusions underwent PFA including ADA and PCR [65 kDa gene; multiplex (IS6110, protein antigen b, MPB64)]. Patients with exudative pleural effusion undiagnosed after PFA underwent medical thoracoscopy. All 107 patients underwent thoracocentesis with 45 and 62 patients diagnosed as transudative and exudative pleural effusions, respectively. Twenty six of the 62 patients underwent medical thoracoscopy. Tuberculous pleurisy was diagnosed in six while uraemic pleuritis was diagnosed in 20 subjects. The sensitivity and specificity of pleural fluid ADA, 65 kDa gene PCR, and multiplex PCR were 66.7 and 90 per cent, 100 and 50 per cent, and 100 and 100 per cent, respectively. Thoracoscopy was associated with five complications in three patients. Uraemia remains the most common cause of pleural effusion in CKD even in high TB prevalence country. Multiplex PCR and thoracoscopy are useful investigations in the diagnostic work-up of pleural effusions complicating CKD while the sensitivity and/or specificity of ADA and 65 kDa gene PCR is poor.
    The Indian Journal of Medical Research 03/2015; 141(3):308-14.
  • The Indian Journal of Medical Research 03/2015; 141(3):263-5.