Zeitschrift fur Naturforschung C (Z NATURFORSCH C)

Publications in this journal

• Article: Linear Dichroism Spectroscopy of Retinal with Picosecond Time Resolution

  M. E. Lippitsch, M. Riegler, F. R. Aussenegg, N. Friedman, M. Sheves, Y. Mazur, L. Margulies
  Zeitschrift fur Naturforschung C 02/2013; 40:880.
• Article: Induction of Caspase-8 and Death Receptors by a New Dammarane Skeleton from the Dried Fruits of Forsythia koreana

  Usama W. Hawas, Amira M. Gamal-Eldeen, Samy K. El-Desouky, Young-Kyoon Kim, Antje Huefner
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  ABSTRACT: A new naturally occurring compound based on the dammarane skeleton, i.e. cabralealactone 3-acetate-24-methyl ether, was isolated from the aqueous methanolic extract of Forsythia koreana fruits, along with eight known compounds: cabralealactone 3-acetate, ursolic acid, arctigenin, arctiin, phillyrin, rutin, caffeic acid, and rosmarinic acid. The identifi cation of the isolated compounds was based on their spectral analysis including: HREI-MS, 1D and 2D NMR spectroscopy. The selected compounds and the aqueous methanolic extract were evaluated for their cytotoxic activity against human solid tumour cell lines. Cabralealactone 3-acetate-24-methyl ether and ursolic acid were found to be active against human breast cancer cells (MCF-7). The cytotoxicity was associated with the activation of caspase-8, the induction of the death receptors DR4 and DR5, as well as DNA fragmentation, and was thus due to apoptosis rather than necrosis.
  Zeitschrift fur Naturforschung C 01/2013; 68:29-38.
• Article: Antimicribial Isothiocyanates from the seeds of Moringa oleifera Lam.

  Eleanor Padla, Ludivina Solis, Ruel Levida, Chien-Chang Shen, and Consolacion Y. Ragasa
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  ABSTRACT: 4-(α-L-Rhamnosyloxy)benzyl isothiocyanate (1) and 4-(4’-O-acetyl-α-L-rhamnosyloxy)- benzyl isothiocyanate (2) isolated from Moringa oleifera seeds were screened for their antibacterial activities against Staphylococcus aureus, Staphylococcus epidermidis, Bacillus subtilis, Escherichia coli, Enterobacter aerogenes, Klebsiella pneumoniae, and Pseudomonas aeruginosa, and for their antifungal activities against Candida albicans, Trichophyton rubrum, and Epidermophyton fl occosum using the disk diffusion method. Isothiocyanates 1 and 2 were found active at the lowest inhibitory concentration of 1 mg/ml against all Grampositive bacteria tested (S. aureus, S. epidermidis, B. subtilis) and against the dermatophytic fungi E. fl occosum and T. rubrum. Statistically signifi cant differences were found between the mean inhibition zones (IZ) of 1 and 2 and the standard drugs, ofl oxacin and clotrimazole. The minimum inhibitory concentration (MIC) values confi rmed the good antimicrobial activity of 1 and 2 against S. aureus, good to moderate activity against S. epidermidis, moderate activity against B. subtilis, and weak activity against E. fl occosum and T. rubrum. The in vitro bactericidal effect of 1 and 2 against the Gram-positive bacterial strains tested is suggested by MBC:MIC ratios of 2:1.
  Zeitschrift fur Naturforschung C 12/2012; 67c:557-564.
• Article: Correlations among attributes of senescence and antioxidative status of leaf discs during epiphyllous bud differentiation in Kalanchoe pinnata Lam. ( Pers.)

  sarita jaiswal, Raman Chawla, Sudhir Sawhney
  Zeitschrift fur Naturforschung C 08/2012;
• Article: Osama M. Ashour, Ashraf B. Abdel-Naim, Hossam M. Abdallah, Ayman A. Nagy, Ahmed M. Mohamadin, Essam A. Abdel-Sattar. Evaluation of the Potential Cardioprotective Activity of Some Saudi Plants against Doxorubicin Toxicity. Z Natuforsch C. 67, 297-307, 2012.

  Osama M. Ashour, Ashraf B. Abdel-Naim, Hossam M. Abdallah, Ayman A. Nagy, Ahmed M. Mohamadin, Essam A. Abdel-Sattar
  Zeitschrift fur Naturforschung C 01/2012; 67:297-307.
• Article: Bioactive phenolic compounds isolated from Egyptian’s Red Sea seagrass Thalassodendron ciliatum

  Hamdy A.A, Mettwally W.A, Abou El Fotouh M, Rodriguez B, El-Dewany A.I, El-Toumy S. A, Hussein A.A
  Zeitschrift fur Naturforschung C 01/2012; 67 c(67 c):291 – 296.
• Article: Quantification of polyacetylenes in apiaceous plants by high-performance liquid chromatography coupled with diode array detection.

  Maike Kramer, Andrea Mühleis, Jürgen Conrad, Martin Leitenberger, Uwe Beifuss, Reinhold Carle, Dietmar R Kammerer
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  ABSTRACT: Polyacetylenes are known for their biofunctional properties in a wide range of organisms. In the present study, the most frequently occurring polyacetylenes, i.e. falcarinol, falcarindiol, and falcarindiol-3-acetate, were determined in six genera of the Apiaceae family. For this purpose, a straightforward and reliable method for the screening and quantification of the polyacetylenes using high-performance liquid chromatography coupled with diode array and mass spectrometric detection without tedious sample clean-up has been developed. Peak assignment was based on retention times, UV spectra, and mass spectral data. Quantification was carried out using calibration curves of authentic standards isolated from turnip-rooted parsley and Ligusticum mutellina, respectively. The references were unambiguously identified by Fourier transform-IR (FT-IR) spectroscopy, GC-MS, HPLC-MSn in the positive ionization mode, and 1H NMR and 13C NMR spectroscopy. To the best of our knowledge, the occurrence of falcarindiol-3-acetate in Anthriscus sylvestris and Pastinaca sativa has been reported for the first time. The data revealed great differences in the polyacetylene contents and varying proportions of individual compounds in the storage roots of Apiaceous plants. The results of the present study may be used as a suitable tool for authenticity control and applied to identify novel sources devoid or particularly rich in polyacetylenes, thus facilitating breeding programs for the selective enrichment and depletion of these plant secondary metabolites, respectively.
  Zeitschrift fur Naturforschung C 01/2011; 66c:319-27.
• Article: H. M. Abdallah and S. M. Ezzat*, Effect of the Method of Preparation on the Composition and Cytotoxic Activity of the Essential Oil of Pituranthos tortuosus Z. Naturforsch. 66 c, 143 – 148, 2011.

  H. M. Abdallah, S. M. Ezzat
  Zeitschrift fur Naturforschung C 01/2011; 66:143-148.
• Article: A bioactive prodelphinidin from Mangifera indica leaf extract.

  Khaled Tawaha, Rasha Sadi, Fadi Qa'dan, Khalid Z Matalka, Adolf Nahrstedt
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  ABSTRACT: A new trimeric proanthocyanidin, epigallocatechin-3-O-gallat-(4beta-->8)-epigallocatechin-(4beta-->8)-catechin (1), was isolated together with three known flavan-3-ols, catechin (2), epicatechin (3), and epigallocatechin (4), and three dimeric proanthocyanidins, 5-7, from the air-dried leaves of Mangifera indica. Their chemical structures were determined on the basis of 1D- and 2D-NMR spectra (HSQC, HMBC) of their peracetylated derivatives, MALDI-TOF-mass spectra, and by acid-catalyzed degradation with phloroglucinol. The isolated compounds 1-7 were in vitro tested for their inhibitory activities against COX-1 and COX-2. Compound 1 was found to have a potent inhibitory effect on COX-2, while compounds 1 and 5-7 exhibited moderate inhibition against COX-1.
  Zeitschrift fur Naturforschung C 06/2010; 65(5-6):322-6.
• Article: G. A. Fawzy, H. M. Abdallah*, M. S. A. Marzouk, F. M. Soliman, and A. A. Sleem Antidiabetic and Antioxidant Activities of Major Flavonoids of Cynanchum acutum L. (Asclepiadaceae) Growing in Egypt . Zeitschrift für Naturforschung C Vol. 63c, 9/10, 658 – 662, 2008.

  G. A. Fawzy, H. M. Abdallah, M. S. A. Marzouk, F. M. Soliman, A. A. Sleem
  Zeitschrift fur Naturforschung C 01/2008; 63:658-662.
• Article: '' Pyrroles and Pyrrolopyrimidines as a Class of Anti-Inflammatory agents.'' M. S. Mohamed, A.E. Rashad, M. Monem, S. S. Fatahalla, Z. Naturforsch. C, 2007, 62.

  S. S. Fatahalla, M. S. Mohamed, A.E. Rashad, M. Mone
  Zeitschrift fur Naturforschung C 01/2007; 62.