Publisher: Deutsche Gesellschaft für Hals-Nasen-Ohrenheilkunde, Kopf- und Halschirurgie; Österreichische Gesellschaft für Hals-, Nasen-, Ohrenheilkunde, Kopf- und Halschirurgie, Georg Thieme Verlag


Organ der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Halschirurgie; Organ der Österreichischen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Halschirurgie

  • Impact factor
    Hide impact factor history
    Impact factor
  • 5-year impact
  • Cited half-life
  • Immediacy index
  • Eigenfactor
  • Article influence
  • Website
    Laryngo-Rhino-Otologie website
  • ISSN
  • OCLC
  • Material type
    Periodical, Internet resource
  • Document type
    Journal / Magazine / Newspaper, Internet Resource

Publisher details

Georg Thieme Verlag

  • Pre-print
    • Author cannot archive a pre-print version
  • Post-print
    • Author can archive a post-print version
  • Conditions
    • On author's personal website immediately
    • On Institutional Repository and PubMed Central after 12 months embargo
    • Publisher's version/PDF can be used on author's personal website only
    • Publisher copyright and source must be acknowledged
    • Link to Publisher version ( must be included if article has been published online
    • 'Georg Thieme Verlag' is an imprint of 'Thieme Publishing'
  • Classification
    ​ blue

Publications in this journal

  • [Show abstract] [Hide abstract]
    ABSTRACT: Objective: Taste dysfunction is a common side effect during irradiation of head and neck. Our aim was to determine the time-dependent course and a possible dependency of this side effect to the radiation-dose during irradiation with helical tomotherapy. Patients and Methods: 31 patients with malignant tumours in the region of head and neck received an IG-/IM-radiotherapy (helical tomotherapy).The median total dose was 63 Gy (range 30-66 Gy). For all patients the subjective taste dysfunction was documented and correlated to the median (D50) tongue dose. Results: A subjective taste dysfunction was registered by the patients themselves after 9 BT (days of radiotherapy) (median). This correlates to a mean dose (D50) of 15.3 Gy (back third of tongue (back ZD)), 11.3 Gy (middle ZD), 8.2 Gy (front ZD). A subjective ageusia occurred after 15 BT (median) (28.9 Gy (back ZD), 22.2 Gy (middle ZD), 17.7 Gy (front ZD)). A starting recovery was registered by 77% of the patients in the first 6-8 weeks after the end of radiotherapy. Conclusion: The time-dependent course of taste dysfunction during radiotherapy and the following recovery is predictable. A dependency of taste dysfunction to radiation-dose exists. Based on the collected data a targeted dose reduction to the tongue with a view to minimize the taste dysfunction is thinkable and aim of further studies. © Georg Thieme Verlag KG Stuttgart · New York.
    Laryngo-Rhino-Otologie 12/2014;
  • [Show abstract] [Hide abstract]
    ABSTRACT: Background: The use of botulinum toxin injection in the salivary gland, is taking an increasing significance in the treatment of functional hypersalivation today. With due regard to the off -label use and the prospect of success, dosage levels are not yet standardized. Material and methods: In a retrospective study, 54 patients resp. 117 treatments were analysed over a period of 5 years according to their dosage levels of botulinum toxin, outcome and side effects. Results: In 90% of the cases, a reduction of saliva after botulinum toxin injections was reported, although a significant number of patients wished for an even greater effect. Compared to the first botulinum toxin injection, we therefore used a higher dosage plan in the following treatment in order to achieve better clinical results. Besides not enough saliva reduction, the main side effects were swallowing problems and thick or sticky saliva in patients with a tracheal cannula. With the exception of insufficient saliva reduction, the other described side effects were irrespective to the dosage level. Conclusions: Botulinum toxin injection as a treatment of hypersalivation is an effective method with only minor side effects, even in increased dosage levels. Nevertheless, certain modifications according to each individual treatment are required. Possible side effects such as swallowing problems or non-responding situations should always be part of informed consent, especially as the latter is even possible for higher dosage levels. © Georg Thieme Verlag KG Stuttgart · New York.
    Laryngo-Rhino-Otologie 12/2014;
  • Laryngo-Rhino-Otologie 12/2014; 93(12):811-2.
  • Laryngo-Rhino-Otologie 12/2014; 93(12):887.
  • [Show abstract] [Hide abstract]
    ABSTRACT: In recent decades, the endoscopic methods and technologies for laryngeal examination have improved so much that not only epithelial changes, but also vascular changes are recognizable at earlier stages. When comparing newer and older literature, the associated increasingly differentiated descriptions of such visible vascular changes of the vocal folds lead to terminological blurring and shifts of meaning. This complicates the technical-scientific discourse. The aim of the present work is a theoretical and conceptual clarification of early vascular changes of vocal folds. Horizontal changes of benigne vascular diseases, e. g. vessel ectasia, meander, increasing number and branching of vessels, change of direction may develop in to manifest vascular lesions, like varicosis, polyps and in case of ruptures to haemorrhages of vocal folds. These beginning and reversible vascular changes, when early detected and discussed basing on etiological knowledge, may lead to more differentiated prognostic statements and adequate therapeutic decisions, e. g. phonosurgery, functional voice therapy, voice hygiene and voice rest. Vertical vascular changes, like vessel loops, occur primarily in laryngeal papilloma, pre-cancerous and cancerous changes of the vocal folds. Already in small cancerous lesions of the vocal folds the vascular architecture is completely destroyed. © Georg Thieme Verlag KG Stuttgart · New York.
    Laryngo-Rhino-Otologie 12/2014; 93(12):819-30.
  • [Show abstract] [Hide abstract]
    ABSTRACT: Nasal obstruction can have a variety of different causes. The following text describes important diseases of the nose and paranasal sinuses, which are associated with the symptom of nasal obstruction and discusses specifics of diagnosis and therapy. © Georg Thieme Verlag KG Stuttgart · New York.
    Laryngo-Rhino-Otologie 12/2014; 93(12):867-86.
  • Laryngo-Rhino-Otologie 12/2014; 93(12):861-4.
  • [Show abstract] [Hide abstract]
    ABSTRACT: Background: The number of elderly patients with indication for cochlear implantation is increasing. Our aim was to investigate whether seniors with cochlea implants differ from younger patients with regard to hearing improvement, surgical complications and rehabilitation. Patients and Methods: Patients older than 60 years (ys) having received a cochlea implant in 2007-2012 were included (Group I 60-70 ys; Group II <70 ys). Preoperative risk factors according to ASA-Criteria and postoperative complications were analyzed. Improvements in quality of live were evaluated by questionnaire. Audiological outcome was tested by Freiburger speech test and OLSA sentence test with background noise. Patients with comparable conditions for cochlea implantation between 40 and 59 years of age served as control group (Group K). Results: Patient cohort consisted of 94 patients, 29 of which being older than 70 years. Severe complications were inexistent postoperatively. Gr. II achieved a speech perception for numbers of 95% (65 dB) and 50% (65 dB) for monosyllables. The speech perception in Gr. II was not significantly different from Gr. I or K. According to the quality of life test all groups experienced an improvement in their social life. Conclusion: Old age itself is no contraindication to cochlea implantation. It has little influence on the postoperative speech perception even though the learning curve of the elderly rises slower. However, careful assessment with regard to surgical risk factors and expected outcome is necessary. © Georg Thieme Verlag KG Stuttgart · New York.
    Laryngo-Rhino-Otologie 12/2014;
  • Laryngo-Rhino-Otologie 11/2014;
  • Laryngo-Rhino-Otologie 11/2014;
  • [Show abstract] [Hide abstract]
    ABSTRACT: Hintergrund Die fiberoptisch endoskopische Evaluation des Schluckvorganges (FEES) ist, durchgeführt nach Langmore-Protokoll, international als Goldstandard in der apparativen Schluckdiagnostik etabliert. Zur Dokumentation und Qualitätssicherung wird die Videoaufzeichnung der FEES empfohlen. Doch häufig erfolgt dies z. B. bei Bedside-Diagnostik nicht aufgrund eingeschränkter Verfügbarkeit portabler Aufzeichnungssysteme. Ziel der vorgelegten Studie ist daher der Vergleich der Qualitätssicherung einer FEES mit und ohne Videoaufzeichnung anhand der Beurteilung des Kardinalmerkmals einer Schluckstörung, der Penetration bzw. Aspiration, definiert nach der Penetrations-Aspirations-Skala (PAS) nach Rosenbek. Material und Methoden Anhand von 80 Videosequenzen, beurteilt durch vier unabhängige Rater in zwei Beurteilungsmodi A) „Echtzeit“, B) „Bild-für-Bild“, erfolgte eine Überprüfung der Übereinstimmung der Penetrations- und Aspirationsgrade mit definiertem Referenzstandard. Ergebnisse Bei der Intra- und Interrater-Reliabilität zeigten sich höhere Übereinstimmungen im Beurteilungsmodus B als bei A. Auch die Übereinstimmungsvalidität mit dem Referenzstandard zeigte für B deutliche höhere Korrelationswerte als für A, mit jeweils signifikanten Unterschieden zugunsten von B, dem Beurteilungsmodus, der die Auswertung anhand videoaufgezeichneter FEES darstellt. Schlussfolgerung Die vorliegenden Studienergebnisse unterstreichen die Notwendigkeit der Videoaufzeichnung einer FEES-Diagnostik bei nachgewiesen besserer Beurteilungsreliabilität und -validität, mindestens in der Beurteilung der Penetration bzw. Aspiration.
    Laryngo-Rhino-Otologie 11/2014; 93:1-5.
  • [Show abstract] [Hide abstract]
    ABSTRACT: Background: Epidemiological data on HNC are often reported aggregated despite their anatomical and histological heterogeneity. In Germany, few studies have analyzed incidence and mortality trends separately for specific anatomic sites. Furthermore, little is known about whether the incidence of HPV-associated tumour entities of the head and neck region has increased. Methods: Based on cancer registry data from Rhineland-Palatinate from 2000 to 2009, age-standardized incidence and mortality rates were calculated for all HNC sites and localisation groups that might be HPV-associated according to the literature. Trends were analyzed by Joinpoint regression and reported as the annual percentage change (APC). Results: Throughout the study period, 8 055 incident cases and 3 177 deaths were identified. The incidence rates of overall HNC increased among women (APC:+2.2%) and declined slightly among men (- 0.9%). Significantly increasing incidence rates among women were seen for tumours of the oral cavity (+2.7%) and the oropharynx (+3.6%). Among men, a significant decrease in incidence rates for tumours of the hypopharynx (-3.4%) and the larynx (-2.7%) are noteworthy. Cancers at HPV-associated sites showed increased incidence rates in men (+3.3%) and women (+4.3%). A decrease in mortality was found for tumours of the larynx in both sexes (-5.8% men,-9.1% women). Conclusions: A detailed analysis by localisation of HNC showed significant and often opposing trends for men and women regarding incidence and mortality. © Georg Thieme Verlag KG Stuttgart · New York.
    Laryngo-Rhino-Otologie 11/2014;
  • [Show abstract] [Hide abstract]
    ABSTRACT: Objective: To investigate the diagnostic performance of an testbattery. Sensitivity and specificity are measures to evaluate the validity of a test. Material and Methods: These parameters were determined using ROC-curves for a battery of 10 diagnostic tests. The Youden Index, defined as the maximal effectiveness to determine the optimal cutpoint of diagnostic accuracy, was calculated as well. Participants: 91 children diagnosed with APD (51%) visiting 2(nd)-4(th) grade of a primary school; 87 2(nd)-4(th) graders with-out APD. Results: A very good relation of sensitivity and false-positive-rate was found for the Mottier-Test, which measures auditory non-word repetition (Area under the Curve=AUC as a global statistic measure for validity: 0.96; p=0.000; 95%-CI: 0.93-0.99). The cut-off point to distinguish between children with and without APD was 17.5 raw score, according to the max. Youden Index 0.83 (sensitivity: 90.1%; specificity 93.1%; false-positive-rate: 6.9%). The HSET-Subtest "Imitation grammatischer Strukturformen" (measuring auditory short-term sentence memory) exhibited comparable high discriminative power (AUC: 0.94; p=0.000; 95%-CI: 0.90-0.98). At 21.5 raw score (max. Youden Index: 0.82), 84.7% of the children were classified correctly (false-positive-rate: 2.3%; specificity: 97.7%). Eight tests had a moderately diagnostic accuracy, two of them tended to lesser accuracy (phoneme analysis: AUC: 0.72; monaural temporal order judgment AUC: 0.75). Conclusions: Using certain tests of a defined test set for identification of APDs in primary school children according to the sensitivity improves the possibility to detect APDs. In order to precisely specify the APD and to decide which auditory dimension should be treated the entire combination of 10 diagnostic tests is indispensable. © Georg Thieme Verlag KG Stuttgart · New York.
    Laryngo-Rhino-Otologie 11/2014;
  • Laryngo-Rhino-Otologie 11/2014;
  • Laryngo-Rhino-Otologie 11/2014;
  • Laryngo-Rhino-Otologie 11/2014;
  • [Show abstract] [Hide abstract]
    ABSTRACT: Background: By considering their general development, 2-year-old children with delayed speech development (late -talkers, LT) were examined and described with respect to lingui-stic competence and hearing. Methods: Initially, 50 monolingual German speaking LT (age: 23-28 months) were recruited. In addition to audiological tests (impedance testing, otoacoustic emissions, reaction audiometry), language development status test was performed (clinical impression during examination, expressive vocabulary: FRAKIS, receptive competence: SETK-2). Results: After exclusion of 10 children with general retarded development (3 premature infants, 2 children with suspicion of autism and 2 children with infantile brain damage) 33 LTs with normal hearing were included. The expressive vocabulary (FRAKIS) of 82% of these 33 LTs were below the normal range. 39% showed deficits in language comprehension tests (SETK-2) although parental reports mentioned language comprehension problems in only 3 LT. No correlation was found between vocabulary (FRAKIS) and language comprehension (SETK-2). Conclusion: The clinical collective in this study showed severely affected children with a high percentage of other abnormalities and speech perception problems in many cases. Despite normal hearing, vocabulary and especially speech comprehen-sion should also be tested. LT with language comprehension problems require early developmental psychological investigation in order to prevent language and general developmental limitations. Only in this way, remedial instruction adapted to the develop-mental level can be initiated. © Georg Thieme Verlag KG Stuttgart · New York.
    Laryngo-Rhino-Otologie 11/2014;
  • Laryngo-Rhino-Otologie 11/2014; 93(11):730-1.
  • Laryngo-Rhino-Otologie 11/2014; 93(11):732-3.