Ophthalmic Epidemiology (OPHTHAL EPIDEMIOL)

Publisher: International Society of Geographical and Epidemiological Ophthalmology, Informa Healthcare

Journal description

Ophthalmic Epidemiology is a refereed international journal dedicated to publication of solid original articles that cover the broad scope of ophthalmic research in the fields of epidemiology, public health and prevention of blindness. The journal contains new and topical information useful to a wide variety of specialists.

Current impact factor: 1.27

Impact Factor Rankings

2015 Impact Factor Available summer 2015
2013 / 2014 Impact Factor 1.271
2012 Impact Factor 2.182
2011 Impact Factor 1.453
2010 Impact Factor 1.364
2009 Impact Factor 1.927
2008 Impact Factor 1.369
2007 Impact Factor 1.341
2006 Impact Factor 1.64
2005 Impact Factor 1.19
2004 Impact Factor 1.246

Impact factor over time

Impact factor
Year

Additional details

5-year impact 2.30
Cited half-life 5.90
Immediacy index 0.37
Eigenfactor 0.00
Article influence 0.85
Website Ophthalmic Epidemiology website
ISSN 0928-6586
OCLC 30751029
Material type Periodical, Internet resource
Document type Journal / Magazine / Newspaper, Internet Resource

Publisher details

Informa Healthcare

  • Pre-print
    • Author can archive a pre-print version
  • Post-print
    • Author cannot archive a post-print version
  • Restrictions
    • 12 months embargo
  • Conditions
    • On author's personal website or institution website
    • Publisher copyright and source must be acknowledged
    • On a non-profit server
    • Must link to publisher version
    • Publisher's version/PDF cannot be used
    • NIH funded authors may post articles to PubMed Central for release 12 months after publication
    • Wellcome Trust authors may deposit in Europe PMC after 6 months
  • Classification
    ​ yellow

Publications in this journal

  • [Show abstract] [Hide abstract]
    ABSTRACT: To determine the prevalence and associated factors of pinguecula in a rural Chinese population aged ≥50 years in Eastern China. This cross-sectional, population-based survey included an age-stratified random sample of 1108 residents living in Lvxiang Town of Jinshan District. Participants were requested to complete a comprehensive questionnaire to collect demographic data, history of systemic diseases and lifestyle details. The presence of pinguecula on slit lamp examination was recorded. The prevalence of pinguecula and its associated factors were investigated by logistic regression models. Among 1108 eligible subjects, 959 participated in the study, with an average age of 65.1 ± 9.2 years (range 50-89 years). The overall age-adjusted prevalence of pinguecula in this population was 75.57% (95% confidence interval 71.79-79.35%). Logistic regression analysis revealed that age (p = 0.002) and working outdoors (daily sunlight exposure ≥2 hours; p = 0.001) were independent risk factors for pinguecula. In addition, sex, education level, alcohol intake, smoking and decreased tear break-up time did not have associations with the development of pinguecula after adjusting for age and outdoor work occupations. The prevalence of pinguecula was 75.57% in this Chinese population aged ≥ 50 years from a coastal rural area of Shanghai, Eastern China, which was higher than the majority of previous findings. Age and working outdoors were independent risk factors for pinguecula.
    Ophthalmic Epidemiology 04/2015; 22(2):130-8. DOI:10.3109/09286586.2015.1012269
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    ABSTRACT: To determine factors associated with angle-closure disease, particularly in those with structural or functional damage to the eyes, in an elderly Chinese population. A total of 460 individuals aged over 72 years were recruited. The association of angle-closure diseases, including primary angle-closure suspect (PACS), primary angle-closure (PAC) and primary angle-closure glaucoma (PACG), with various systemic and ocular characteristics was evaluated using multivariate logistic regression analyses. Of 374 phakic subjects, 199 (53.2%) had angle-closure disease, including 135 PACS, 46 PAC, and 18 PACG. The majority of those with untreated PACG (10/13, 76.9%) had presenting intraocular pressure (IOP) < 20 mmHg. Independent risk factors for angle-closure disease were lower Van Herick grading, shallower central anterior chamber depth (ACD), and higher post-mydriatic IOP (all p < 0.05). Central and peripheral ACD estimation correlated weakly, only 60.8% of angle-closure eyes had generalized narrowing of ACD as a Van Herick grading ≤2 and central ACD ≤ 2.83 mm. A criterion considering either central or peripheral ACD identified 91% of angle-closure eyes, including all PACG. A higher post-mydriatic IOP was associated with a diagnosis of PAC or PACG among angle-closure eyes (p = 0.002). Both central and peripheral ACD should be evaluated and shallowing of either one should be an indication for gonioscopic examination to maximize detection of angle-closure disease in elderly Chinese persons. PAC and PACG were associated with higher post-mydriatic IOP than PACS, although subjects with PACG frequently presented with normal IOP.
    Ophthalmic Epidemiology 04/2015; 22(2):109-15. DOI:10.3109/09286586.2015.1012270
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    ABSTRACT: To investigate seasonality in onset and incidence of central retinal vein occlusion (CRVO) in Stockholm, Sweden. A retrospective consecutive population-based case series of patients presenting to the emergency department with CRVO from January 2008 through December 2013 at the St Erik Eye Hospital. Date, age at occurrence and sex were recorded in the study cohort. A total of 854 patients presented with CRVO during the study period. Peak CRVO onset occurred during the winter/spring period and was significantly higher than during the summer/autumn period. The number of patients presenting by season were: 166 (28.8%, 95% confidence interval, CI, 25.3-32.6%) in winter, 172 (29.9%, 95% CI 26.3-33.7%) in spring, 131 (22.7%, 95% CI 19.5-26.3%) in summer, and 107 (18.9%, 95% CI 15.6-22.0%) in autumn (p < 0.0002). There were more males, accounting for 53.9% of subjects (460/856; p = 0.029). Mean annual incidence of CRVO was 2/10,000 for persons aged over 40 years, increasing from 0.25/10,000 at 45 years to 7/10,000 at 85 years (p < 0.001). The onset of CRVO in Stockholm, Sweden, had a significant seasonal pattern and most cases occurred during the winter-spring period. The highest incidence of CRVO was found in elderly people.
    Ophthalmic Epidemiology 04/2015; 22(2):94-7. DOI:10.3109/09286586.2015.1012271
  • Ophthalmic Epidemiology 04/2015; 22(2):142-3. DOI:10.3109/09286586.2015.1010690
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    ABSTRACT: To report on the accuracy of the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes for identifying patients with polymyalgia rheumatica (PMR) and concurrent noninfectious inflammatory ocular conditions in a large healthcare organization database. Queries for patients with PMR and uveitis or scleritis were executed in two general teaching hospitals' databases. Patients with ocular infections or other rheumatologic conditions were excluded. Patients with PMR and ocular inflammation were identified, and medical records were reviewed to confirm accuracy. The query identified 10,697 patients with the ICD-9-CM code for PMR and 4154 patients with the codes for noninfectious inflammatory ocular conditions. The number of patients with both PMR and noninfectious uveitis or scleritis by ICD-9-CM codes was 66. On detailed review of the charts of these 66 patients, 31 (47%) had a clinical diagnosis of PMR, 43 (65%) had noninfectious uveitis or scleritis, and only 20 (30%) had PMR with concurrent noninfectious uveitis or scleritis confirmed based on clinical notes. While the use of ICD-9-CM codes has been validated for medical research of common diseases, our results suggest that ICD-9-CM codes may be of limited value for epidemiological investigations of diseases which can be more difficult to diagnose. The ICD-9-CM codes for rarer diseases (PMR, uveitis and scleritis) did not reflect the true clinical problem in a large proportion of our patients. This is particularly true when coding is performed by physicians outside the area of specialty of the diagnosis.
    Ophthalmic Epidemiology 04/2015; 22(2):139-41. DOI:10.3109/09286586.2015.1012274
  • Ophthalmic Epidemiology 04/2015; 22(2):144. DOI:10.3109/09286586.2015.1010691
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    ABSTRACT: The prevalence and determinants of sudden vision loss (SVL) are unknown in African Americans (AAs). Since SVL can be cardiovascular disease (CVD)-related and CVD is highly prevalent in AAs, we examined the prevalence of and CVD factors related to self-reported SVL lasting 24 hours or longer in the cohort of AAs enrolled in the Jackson Heart Study (JHS). The study population comprised 5301 participants enrolled from 2000-2004 in the metropolitan area of Jackson, MS, USA. All participants who responded to the question "Have you ever had any sudden loss of vision or blurring, lasting 24 hours or longer?" on the baseline stroke questionnaire were included in the study. We estimated the prevalence of SVL and used regression modeling to identify CVD factors independently related to SVL. A total of 5262 participants were included, of which 63% (3334/5262) were female. The prevalence of SVL was 3.6% (193/5262) overall (4.4% in females and 2.4% in males), and 8.7% (84/965) in patients with diabetes mellitus. Factors independently related to SVL included coronary heart disease (odds ratio, OR, 1.69, 95% confidence interval, CI, 1.12-2.56), cerebrovascular disease (OR 2.81, 95% CI 1.76-4.47), diabetes (OR 2.85, 95% CI 2.05-3.94), hypertension (OR 1.64, 95% CI 1.09-2.45), female sex (OR 1.82, 95% CI 1.24-2.67), and income less than US$50,000 (OR 2.05, 95% CI 1.28-3.30). In this cohort of AAs, self-reported SVL lasting 24 hours or longer was highly prevalent in women and those with diabetes and was independently related to sex, CVD, CVD risk factors and household income.
    Ophthalmic Epidemiology 04/2015; 22(2):116-22. DOI:10.3109/09286586.2015.1012273
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    ABSTRACT: Prospective data to examine the association of homocysteine with age-related macular degeneration (AMD) are limited. We examined the prospective relation of plasma homocysteine level and AMD in a large cohort of apparently healthy women. We evaluated the relationship between baseline levels of plasma homocysteine and incident AMD among 27,479 female health professionals aged 40 years or older. Main outcome measures were total AMD, defined as self-report documented by medical record evidence of an initial diagnosis after randomization, and visually significant AMD, defined as confirmed incident AMD with visual acuity 20/30 or worse attributable to this condition. During an average 10 years of follow-up, a total of 452 cases of AMD, including 182 cases of visually significant AMD, were documented. Women in the highest versus lowest quartile of plasma homocysteine had modestly, but statistically non-significant, increased risks of total AMD (hazard ratio, HR, 1.24, 95% confidence interval, CI, 0.95-1.63; p for trend 0.07) and visually significant AMD (HR 1.41, 95% CI 0.92-2.17; p for trend 0.052) in age- and treatment-adjusted analyses. These prospective data from a large cohort of apparently healthy women do not support a strong role for homocysteine in AMD occurrence.
    Ophthalmic Epidemiology 04/2015; 22(2):85-93. DOI:10.3109/09286586.2015.1012272
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    ABSTRACT: To determine and compare the prevalence of age-related macular degeneration (AMD) in older Australians of Anglo-Celtic and Southern European origin. A total of 21,132 participants of the Melbourne Collaborative Cohort Study, aged 47-86 years, were assessed for AMD in 2003-2007 with non-mydriatic fundus photography. Of these, 14% were born in Southern Europe (Greece, Italy or Malta), with the remaining 86% of Anglo-Celtic origin, born in Australia, the United Kingdom or New Zealand. Overall, 2694 participants (12.7%) had early stages of AMD, defined as either one or more drusen ≥125 μm (with or without pigmentary abnormalities) or one or more drusen 63-124 μm with pigmentary abnormalities in a 6000-μm diameter grading grid, in the absence of late AMD in either eye. A total of 122 participants (0.6%) had late AMD, defined as either geographic atrophy or neovascular AMD. In logistic regression analysis, adjusted for age, sex, smoking, education and physical activity, Southern Europeans compared to Anglo-Celts had a higher prevalence of the early stages of AMD (odds ratio, OR, 1.15, 95% confidence interval, CI, 1.00-1.34), and lower prevalence of late AMD (OR 0.36, 95% CI 0.17-0.78). Australians of Southern European origin have a higher prevalence of the early stages of AMD and lower prevalence of late AMD compared to those of Anglo-Celtic origin. Although AMD prevalence in the older age group(s) of Southern Europeans could be underestimated due to disparity in participation rates, it is likely that both lifestyle and genetic factors play their parts in differential AMD prevalence in these ethnic groups.
    Ophthalmic Epidemiology 04/2015; 22(2):75-84. DOI:10.3109/09286586.2015.1010688
  • Ophthalmic Epidemiology 01/2015; 22(1). DOI:10.3109/09286586.2014.988878
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    ABSTRACT: Abstract Purpose: While quality of life surveys have been conducted in trachomatous trichiasis (TT) surgery populations, little is known about patients' perceptions of the surgical experience and outcomes. Methods: We interviewed a subset of Partnership for the Rapid Elimination of Trachoma surgery trial participants 24 months after surgery. Questions focused on current ocular symptoms, perceived daily functioning, physical appearance, and overall perception of surgery. We stratified participants based on surgical outcomes: normal upper eyelid, postoperative TT, or eyelid contour abnormality (ECA) in one or both eyelids. We compared responses between sexes and surgical outcome groups using contingency tables and Fisher's exact tests. Results: A total of 483 individuals participated and 86% were very satisfied with surgery results; 96% reported ocular symptom improvement. Participants with moderate to severe ECA or postoperative TT were more likely to report current ocular problems than those with normal eyelids (46% and 58% vs 34%, respectively; p = 0.01 for each comparison). The most common symptom among participants with moderate to severe postoperative TT was feeling lashes touching (blurred vision was the most common among participants with moderate to severe ECA. Overall, 83% stated surgery improved daily life; participants with ECA were less likely to report improvement than others (p = 0.002). Participants who had moderate or severe postoperative TT were least likely to state that they would undergo repeat surgery (80%), followed by participants with ECA (86%). Conclusions: Postoperative TT and ECA both reduced satisfaction with surgery, but appeared to influence different aspects of life. Improving surgical outcomes both by reducing recurrence rates and limiting ECAs are essential.
    Ophthalmic Epidemiology 12/2014; DOI:10.3109/09286586.2014.988873
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    ABSTRACT: ABSTRACT Purpose: To evaluate the cost-effectiveness for a screening interval longer than 1 year detecting diabetic retinopathy (DR) through the estimation of incremental costs per quality-adjusted life year (QALY) based on the best available clinical data in Japan. Methods: A Markov model with a probabilistic cohort analysis was framed to calculate incremental costs per QALY gained by implementing a screening program detecting DR in Japan. A 1-year cycle length and population size of 50,000 with a 50-year time horizon (age 40-90 years) was used. Best available clinical data from publications and national surveillance data was used, and a model was designed including current diagnosis and management of DR with corresponding visual outcomes. One-way and probabilistic sensitivity analyses were performed considering uncertainties in the parameters. Results: In the base-case analysis, the strategy with a screening program resulted in an incremental cost of 5,147 Japanese yen (¥; US$64.6) and incremental effectiveness of 0.0054 QALYs per person screened. The incremental cost-effectiveness ratio was ¥944,981 (US$11,857) per QALY. The simulation suggested that screening would result in a significant reduction in blindness in people aged 40 years or over (-16%). Sensitivity analyses suggested that in order to achieve both reductions in blindness and cost-effectiveness in Japan, the screening program should screen those aged 53-84 years, at intervals of 3 years or less. Conclusions: An eye screening program in Japan would be cost-effective in detecting DR and preventing blindness from DR, even allowing for the uncertainties in estimates of costs, utility, and current management of DR.
    Ophthalmic Epidemiology 12/2014; 22(1):1-9. DOI:10.3109/09286586.2014.988876
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    ABSTRACT: Purpose: This review assessed the effectiveness of diabetic retinopathy (DR) screening programs, using retinal photography in Australian urban and rural settings, and considered implications for public health strategy and policy. Methods: An electronic search of MEDLINE, PubMed, and Embase for studies published between 1 January 1996 and the 30 June 2013 was undertaken. Key search terms were “diabetic retinopathy,” “screening,” “retinal photography” and “Australia.” Results: Twelve peer-reviewed publications were identified. The 14 DR screening programs identified from the 12 publications were successfully undertaken in urban, rural and remote communities across Australia. Locations included a pathology collection center, and Indigenous primary health care and Aboriginal community controlled organizations. Each intervention using retinal photography was highly effective at increasing the number of people who underwent screening for DR. The review identified that prior to commencement of the screening programs a median of 48% (range 16–85%) of those screened had not undergone a retinal examination within the recommended time frame (every year for Indigenous people and every 2 years for non-Indigenous people in Australia). A median of 16% (range 0–45%) of study participants had evidence of DR. Conclusions: This review has shown there have been many pilot and demonstration projects in rural and urban Australia that confirm the effectiveness of retinal photography-based screening for DR.
    Ophthalmic Epidemiology 12/2014; 22(1). DOI:10.3109/09286586.2014.988875
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    ABSTRACT: Abstract Purpose: To investigate the association between potential risk factors for myopia and its progression in young adult Taiwanese men. Methods: A survey of male military conscripts (aged 18-24 years) was conducted from February 2010 to March 2011 in Taiwan. Participants underwent comprehensive eye examinations, including measurements of axial length and corneal radius by optical biometry and non-cycloplegic autorefraction. Participants also provided self-reported progression of myopia and information regarding potential risk factors, including age, parental myopia, educational level, close work, outdoor activities, and urbanization. Results: Of 5145 eligible participants, 5048 (98.11%) provided refraction and questionnaire data; 2316 (45.88%) of the 5048 also had biometric measurements. The prevalence of myopia was 86.1% in this group, with a mean refractive error of -3.66 diopters (D). Of the 5048 participants, 1376 (27.3%) had experienced progression of their myopia during the past year. There were trends for a higher prevalence of myopia among older participants (p = 0.014), those with a history of parental myopia (p < 0.001), higher levels of education (p = 0.001), increased time spent reading (p < 0.001), less time outdoors (p = 0.003), and higher levels of urbanization (p = 0.010). However, only parental myopia, close work, and higher urbanization levels were significantly associated with self-reported progression of myopia. Conclusion: Older age, parental myopia, higher educational level, close work, fewer outdoor activities, and higher urbanization level were associated with the prevalence of myopia in Taiwanese men.
    Ophthalmic Epidemiology 12/2014; 22(1):1-8. DOI:10.3109/09286586.2014.988874
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    ABSTRACT: Aim: To study the effectiveness and cost of a new school vision screening program involving all class teachers (ACTs) compared with the standard program involving a limited number of selected teachers (STs) in Southern India. Methods: A total of 12 schools were selected for intervention and 12 schools were matched as controls, from in and around Pondicherry, India. Teachers in both the intervention arm (ACTs) and the standard arm (STs) were trained to identify students between the ages of 6 and 17 years with visual acuity ≤20/30 in either eye or obvious ocular abnormalities and refer them to an ophthalmic team. The ophthalmic team, including an ophthalmologist, visited the schools to examine all children referred by teachers, provided medical treatment or a prescription for glasses, or referred them to the base hospital if required. Results: ACTs (761 teachers) screened 39,357 children (97.7%) and STs (156 teachers) screened 38,469 children (95.7%). ACTs found significantly fewer screen-positive children (n = 3806, 9.7%) than the STs (n = 6387, 16.6%; p < 0.001), but had a significantly larger number of children with actual vision loss and other ocular pathology (2231, 5.7% and 1554, 4.0%, respectively, p < 0.001). More children from ACTs than STs reached the base hospital for further investigation within 3 months (p < 0.001). The cost of screening per child with actual ocular pathology was estimated to be US$1.91 for ACTs and US$4.83 for STs. Conclusions: A school vision screening program involving ACTs resulted in more efficient screening than a program involving STs at about a third of the cost and also improved compliance with hospital referral.
    Ophthalmic Epidemiology 12/2014; 22(1). DOI:10.3109/09286586.2014.988877
  • Ophthalmic Epidemiology 11/2014; 21(6). DOI:10.3109/09286586.2014.966850
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    ABSTRACT: Purpose: To report functional outcomes following cataract surgery in Timor-Leste. Methods: Pre- and post-intervention study measuring visual function improvement following cataract surgery. Presenting visual acuity (VA) was measured and visual function documented using the Indian vision function questionnaire (IND-VFQ). Results: All 174 persons undergoing cataract surgery from November 2009 to January 2011 in Timor-Leste were included. Mean age was 65.4 years; 113 (64.9%) were male, 143 (82.1%) were from a rural background and 151 (86.8%) were illiterate. Pre-operatively, 77 of 174 patients (44.3%, 95% confidence interval, CI, 37.0–51.7%) were blind (VA ≤3/60), 77 (44.3%, 95% CI 37.0–51.7%) were visually impaired (VA <6/18–>3/60), while 20 (11.5%, 95% CI 7.4–16.9%) had presenting acuity ≥6/18 in the better eye. Following surgery, significant improvement in visual function was demonstrated by an effect size of 2.8, 3.7 and 3.9 in the domains of general functioning, psychosocial impact and visual symptoms, respectively. Four weeks following surgery, 85 patients (48.9%, 95% CI 41.5–66.3%) had a presenting VA ≥6/18, 74 (42.5%, 95% CI 35.3–45.9%) were visually impaired and 15 (8.6%, 95% CI 5.0–13.6%) were blind. IND-VFQ improvement occurred even in patients remaining visually impaired or blind following surgery. Conclusion: In this setting, cataract surgery led to a significant improvement in visual function but the VA results did not meet World Health Organization quality criteria. IND-VFQ results, although complementary to clinical VA outcomes did not, in isolation, reflect the need to improve program quality.
    Ophthalmic Epidemiology 10/2014; 21(6). DOI:10.3109/09286586.2014.975824