Sensors and Actuators B Chemical (SENSOR ACTUAT B-CHEM)

Publisher: Elsevier

Journal description

Sensors & Actuators, B: Chemical is an interdisciplinary journal dedicated to covering research and development in the field of chemical sensors, actuators and microsystems. The scope of the journal encompasses, but is not restricted to, the following areas: Sensing principles and mechanisms New materials development (transducers and sensitive/recognition components) Fabrication technology Actuators Optical devices Electrochemical devices Mass-sensitive devices Gas sensors Biosensors Analytical microsystems Environmental, process control and biomedical applications Signal processing Sensor and sensor-array chemometrics uTAS - Micro Total Analysis Systems Microsystems for the generation, handling and analysis of (bio)chemical information The special section of Sensors & Actuators, B: Chemical on uTAS is dedicated to contributions concerning miniaturised systems for (bio)chemical synthesis and analysis, also comprising work on Bio-MEMS, Lab-on-a-chip, biochips and microfluidics. Topics covered by the uTAS section include: Physics and chemistry of microfluidics Microfabrication technology for uTAS Analytical chemical aspects Detectors, sensors, arrays for uTAS uTAS applications DNA analysis Microinstrumentation Microsystems for combinatorial chemistry

Current impact factor: 3.84

Impact Factor Rankings

2015 Impact Factor Available summer 2015
2013 / 2014 Impact Factor 3.84
2012 Impact Factor 3.535
2011 Impact Factor 3.898
2010 Impact Factor 3.368
2009 Impact Factor 3.083
2008 Impact Factor 3.122
2007 Impact Factor 2.934
2006 Impact Factor 2.331
2005 Impact Factor 2.646
2004 Impact Factor 2.083
2003 Impact Factor 2.391
2002 Impact Factor 1.893
2001 Impact Factor 1.44
2000 Impact Factor 1.47
1999 Impact Factor 1.572
1998 Impact Factor 1.131
1997 Impact Factor 0.858
1996 Impact Factor 0.905
1995 Impact Factor 1.333
1994 Impact Factor 1.074
1993 Impact Factor 1.21
1992 Impact Factor 1.852

Impact factor over time

Impact factor

Additional details

5-year impact 3.67
Cited half-life 5.80
Immediacy index 0.53
Eigenfactor 0.05
Article influence 0.76
Website Sensors and Actuators B: Chemical website
Other titles TAS., Sensors and actuators., Chemical
ISSN 0925-4005
OCLC 39224654
Material type Document, Periodical, Internet resource
Document type Internet Resource, Computer File, Journal / Magazine / Newspaper

Publisher details


  • Pre-print
    • Author can archive a pre-print version
  • Post-print
    • Author can archive a post-print version
  • Conditions
    • Pre-print allowed on any website or open access repository
    • Voluntary deposit by author of authors post-print allowed on authors' personal website, or institutions open scholarly website including Institutional Repository, without embargo, where there is not a policy or mandate
    • Deposit due to Funding Body, Institutional and Governmental policy or mandate only allowed where separate agreement between repository and the publisher exists.
    • Permitted deposit due to Funding Body, Institutional and Governmental policy or mandate, may be required to comply with embargo periods of 12 months to 48 months .
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    • Published source must be acknowledged
    • Must link to journal home page or articles' DOI
    • Publisher's version/PDF cannot be used
    • Articles in some journals can be made Open Access on payment of additional charge
    • NIH Authors articles will be submitted to PubMed Central after 12 months
    • Publisher last contacted on 18/10/2013
  • Classification
    ​ green

Publications in this journal

  • [Show abstract] [Hide abstract]
    ABSTRACT: N6-methyladenosine (m6A) is a ubiquitous modification in mRNA and other RNAs across most eukaryotes, which is likely dynamically regulated throughout developmental processes. In this work, an electrochemical immunosensor was fabricated for RNA methylation detection using gold nanoparticles modified glassy carbon electrode (AuNPs/GCE) as substrate electrode. The assembly of 4-aminophenylboronic acid on AuNPs/GCE triggered the further immobilization of anti-m6A antibody on the substrate electrode through the specific interaction between boric acid and glycosyl of antibody, which led to the following capture of methylated RNA through the immunoreaction. A decreased electrochemical reduction signal of the redox probe of [Fe(CN)6]3− was obtained based on the synergistic effect of electrostatic repulsion and steric hindrance. The developed method showed a wide linear range for methylated RNA from 0.01 to 10 nM and the detection limit was 2.57 pM (S/N = 3). Moreover, the down-regulated expression of methylation level of mRNA in the leaves of rice seedlings after incubation with 6-benzylaminopurine was confirmed by the fabricated biosensor, indicating the great potential for assaying the expression level of methylated RNA in real sample.
    Sensors and Actuators B Chemical 12/2015; 221. DOI:10.1016/j.snb.2015.06.045
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    ABSTRACT: Quantum dot sensitized photoanodes have drawn much attention due to their high potential as efficient anodes for photoelectrochemical (PEC) water splitting or solar cells. However the photocorrosion of QDs is the crucial barrier for applications in these devices. The in situ analysis of photocorrosion is important in understanding its mechanism and also developing the possible solution for photocorrosion. In this study we have developed a novel, integrated analysis system for in situ measurements of photocorrosion and PEC performances. We have fabricated the CdSe/CdS/ZnO nanowire (NW) arrays on quartz crystal microbalance (QCM) as a platform for usage as PEC photoanodes and also mass analysis at the same time. The in situ measuring of photocurrents and mass changes were performed with continuous operation of PEC cells for CdSe/CdS/ZnO NWs photoanode. The study exhibited highly correlated tendency in photocurrent decrease and mass reduction, due to photocorrosion of CdSe/CdS/ZnO NWs. Also to improve the photostability of CdSe/CdS/ZnO NWs, applications of passivation and catalysts were studied and their effects were discussed. Our integrated in situ analysis system is highly applicable to various semiconductor sensitized systems.
    Sensors and Actuators B Chemical 12/2015; 221. DOI:10.1016/j.snb.2015.06.092
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    ABSTRACT: A dual carcinoembryonic antigen (CEA) biosensing alternative optoelectric platforms has been developed based on gold modified ITO electrode. The new platform is constructed by assembly of a thiol-derivative-nanogold (TDN) labeled anti-CEA (TDN-anti-CEA) antibody on a gold/indium tin oxide (ITO) electrode to create a high CEA sensitive surface. The gold film deposited on ITO glass provides a desirable substrate for the immobilization of the TDN-anti-CEA antibody and improves the compatibility between nanogold and electrode which results in a significant amplification. By using the same TDN-anti-CEA antibody probe, the CEA (analyte) was analyzed using two different methods; electrochemical impedance spectroscopy (EIS) and ultraviolet (UV) spectroscopy, the results showed that the limit of detection was 1 and 2 pg/ml by EIS and UV methods, respectively. Given their promising advantages, it is likely that dual platforms will evolve to be an attractive tool for use in many different fields.
    Sensors and Actuators B Chemical 12/2015; 221. DOI:10.1016/j.snb.2015.06.062
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    ABSTRACT: The demand for advanced, sensitive, and low-cost sensor platforms is growing. However, sensors containing biological recognition elements sometimes present restrictions, which limit their use. This work focused on the development of surface plasmon resonance (SPR) based on a molecularly imprinted polymer (MIP) film, which builds a foundation for biomimetic sensors. The MIP films in the sensor chip were prepared by spin-coating method. The MIP film was found to be readily incorporated into the sensor for detection of histamine in aqueous media. The effect of pH conditions was also investigated. The sensing technique allows for the detection of histamine in a wide range of concentration from 25 μg L−1 to 1000 μg L−1. By using structural analogs, the sensor platform was demonstrated to be specific for the detection of histamine.
    Sensors and Actuators B Chemical 12/2015; 221. DOI:10.1016/j.snb.2015.06.058
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    ABSTRACT: SnO2–ZnO hetero-nanofibers were fabricated by a facile electrospinning method and calcination in this study. The SnO2–ZnO nanofibers were characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), Brunauer–Emmett–Teller (BET) and X-ray diffraction (XRD). The gas sensor prepared by the SnO2–ZnO hetero-nanofibers revealed better ethanol sensing performance than pure ZnO and pure SnO2 nanofibers, good stability and excellent selectivity at the optimum temperature of 300 °C. The response and recovery time to 100 ppm ethanol were about 25 s and 9 s, respectively. The growth mechanism of the hetero-nanofibers was discussed, as well as the ethanol adsorption–desorption mechanism.
    Sensors and Actuators B Chemical 12/2015; 221. DOI:10.1016/j.snb.2015.06.104
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    ABSTRACT: Model-based techniques were used to resolve fluorescence datasets related to the interactions of two complementary oligonucleotides (which were tagged by fluorescein and Texas red respectively) in the presence of 13 nm gold nanoparticles (AuNPs). This system was selected as an example to demonstrate the advantages of model-based techniques in studying interactions of nanoparticles and biomolecules, and providing better insight to such nano-bio systems which is in turn helpful for designing more efficient sensor/delivery systems. The adsorption isotherms were analyzed by model-based Scatchard and Langmuir methods and the results were the adsorption constants of the oligonucleotides on AuNPs and the number of binding sites on AuNPs. This is the first reported application of Scatchard method where DNA is the adsorbate. The main part of the study is focused on the application of more sophisticated model-based techniques to analyze complex three-way excitation–emission fluorescence data sets recorded through the adsorption/hybridization process. A novel model-based restricted Tucker3 method is also proposed to estimate the hybridization constant. An advantage of this technique is the estimation of the concentration profiles of all involving chemical components, even those without a fluorescence signal.
    Sensors and Actuators B Chemical 12/2015; 221. DOI:10.1016/j.snb.2015.06.102
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    ABSTRACT: A rapid, facile fluorescence sensing strategy was developed for dopamine (DA) detection based on polydopamine (pDA) formed on the surface of graphene quantum dots (GQDs). The prepared GQDs were strongly luminescent because of the aromatic planar structure. DA could self-polymerize to pDA and snap to the surface of GQDs to form a thin film in alkaline environment, leading to quenching of fluorescence due to fluorescence resonance energy transfer (FRET). With the optimized conditions, the analytical performance illustrated high sensitivity, selectivity in a wide linear range with a detection limit of 8 nM. In addition, the unique method was successfully applied for DA injection test with satisfactory labeled amount. Finally, the proposed strategy was applied for DA detection in serum, wherein accurate results were obtained.
    Sensors and Actuators B Chemical 12/2015; 221. DOI:10.1016/j.snb.2015.06.093
  • Sheik Dawood Shahida Parveen, Basuvaraj Suresh Kumar, Sekar Raj Kumar, Raihana Imran Khan, Kasi Pitchumani
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    ABSTRACT: Biochanin A (BnA) a natural o-methylated isoflavone, is isolated from the leaves of Eupatorium adenaphorum and is effectively utilized as a sensor probe for copper ion with good selectivity and sensitivity. The effect with the presence of other metal ions is also investigated and BnA is found to be selective towards Cu2+ ion over other metal ions such as Zn2+, Sn2+, Ni2+, Ag+, Bi2+, Pb2+, Co3+, In3+, Mn2+, Fe2+, Li+, Hg2+ and Ca2+ at pH 7.1 with a detection limit upto 1.0 × 10−6 mol L−1. The sensor probe BnA exhibits selective fluorescence quenching via an intramolecular charge transfer (ICT) upon addition of Cu2+. The proposed mechanism is strongly supported by TD-DFT calculations and the 1:1 complex (BnA–Cu2+) formation is confirmed by ESI-MS and Job's plot.
    Sensors and Actuators B Chemical 12/2015; 221. DOI:10.1016/j.snb.2015.06.060
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    ABSTRACT: In this work, a novel composite film containing H7P2Mo17V1O62 (P2Mo17V) and Au-Ag bimetallic core–shell nanoparticles (Au@Ag NPs) has been fabricated on quartz slides, silicon wafers and ITO electrodes by the layer-by-layer self-assembly technique. The composite film was characterized by UV–vis spectroscopy, atomic force microscopy (AFM), scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS) and cyclic voltammetry (CV) measurements. Due to the synergistic effect between Au and Ag, the composite film modified electrode showed excellent electrocatalytic activity toward the oxidation of l-cysteine with a broad linear range of 2.5 × 10−8–7.625 × 10−6 M, a low detection limit of 2.76 × 10−8 M (S/N = 3), a high sensitivity of 1.7946 μA/μM and fast response time (<2 s). In addition, the electrode exhibited excellent reproducibility and long-term stability as well as negligible interference from l-tryptophan, l(+)-glutamic acid, citric acid, lactic acid and glucose. Furthermore, the applicability of this sensor was successfully employed to detect l-cysteine in milk samples.
    Sensors and Actuators B Chemical 12/2015; 221. DOI:10.1016/j.snb.2015.06.070
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    ABSTRACT: This work describes the design and fabrication of a novel multianalyte biosensor platform for medical diagnostic applications. The sensor platform consists of a photonic waveguide-based optical circuit used to deliver excitation light to multiple sensor windows on the platform. The platform is fabricated by UV-photopatterning of photocurable hybrid organic–inorganic sol–gel materials. The sensing mechanism is based upon the detection of fluorescently labelled antibodies, in order to determine the concentration of specific analytes in a test solution. Fluorescence is excited by means of the evanescent wave in each sensor window. It is shown that the sensing properties of the platform can be dramatically enhanced by increasing the intensity of the evanescent field of the light propagating in the optical waveguide by a precise design of a high refractive index layer deposited at the waveguide surface. This work proved the concept of employing a waveguide-based photonic platform for the detection of fluorescently labelled antibodies, with μg/ml detection levels, and as such, we believe this system has immense potential for future applications as a medical diagnostic platform.
    Sensors and Actuators B Chemical 12/2015; 221. DOI:10.1016/j.snb.2015.06.012
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    ABSTRACT: A new BODIPY-containing conjugated polymer (P1) had been designed and synthesized as a colorimetric and fluorescent chemosensor for F− and CN−. The combination of advantages of both reaction based sensors and conjugated polymer sensors offered its highly sensitive and selective recognition of F− and CN− with no interference from each other. The addition of F− and CN− to P1 solution induced a rapid color change from purple to orange and faint yellow, respectively. At the same time, the emission color of the P1 solution changed from red to yellow and yellowish green in presence of F− and CN−, respectively. 11B, 19F and 1H NMR spectra indicated that addition of fluoride and cyanide result in a nucleophilic displacement to break a BN bond of P1. In addition, the cell imaging experiments demonstrated that P1 could be successfully applied as a bioimaging agent with good biocompatibility.
    Sensors and Actuators B Chemical 12/2015; 221. DOI:10.1016/j.snb.2015.06.050
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    ABSTRACT: Organophosphate compounds are widely used as pesticides, insecticides, and chemical warfare agents. Biosensors based on acetylcholinesterase (AChE) inhibition and organophosphorus hydrolase (OPH) hydrolysis have been designed for the detection of organophosphate compounds. Since detection with OPH-based biosensors is more direct than that by biosensors based on AChE inhibition, an IrOx potentiometric sensor was fabricated for the direct determination of organophosphate pesticides (OPs). Detection was based on sensing the pH change accompanying the enzymatic hydrolysis of OPs. Paraoxonase 1 (PON1) is a family of OPHs that catalyzes the hydrolyses of OPs to release protons, the concentration of which is proportional to the amount of OPs. A potential change in the IrOx pH-sensing electrode can indicate the presence of OPs. A lower limit of detection for diazinon of 3 μM was obtained. Although this is one to three orders of magnitude higher than that of the measurements based on AChE inhibition for indirect determination, the directness and selectivity of the OP detection are highlights of this potentiometric micro sensor, which make it simpler and quicker.
    Sensors and Actuators B Chemical 12/2015; 220:859-863. DOI:10.1016/j.snb.2015.05.115
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    ABSTRACT: A luminescent lanthanide metal-organic framework (Ln-MOF) thin film of Terbium-Succinate (Tb-SA) was fabricated via one-step electrodeposited onto fluorine-doped tin oxide (FTO) conductive glass under mild condition. The composition of the film was confirmed by powder X-ray diffraction. The morphology was examined by SEM and reveal flower-shaped thin sheet clusters on the surface. The photoluminescence experiment suggests that Tb-SA films exhibits characteristic luminescence of Tb3+ ion, and presents highly eye-detectable luminescent response for Cu2+ ion in aqueous solution. The variations of luminescent intensities are interrelated to the concentration of Cu2+ ion and well-fit with the Stern–Volmer equation over the range of 1 × 10−4–1 × 10−3 M. Furthermore, the film can be used as facile sensor directly for sensing of 0.1 mM Cu(II) in water by naked-eyes under UV-light. The potential quench mechanism was discussed.
    Sensors and Actuators B Chemical 12/2015; 220:779-787. DOI:10.1016/j.snb.2015.05.129
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    ABSTRACT: In this work, a facile approach to sensitively detect sulfide ions is developed. The proposed method is based on the findings that silver ions could oxidize 3,3′,5,5′-tetramethylbenzidine (TMB) to induce a blue color and an absorption peak centered at 652 nm. The introduction of sulfide ions leads to the formation of Ag2S nanoparticles which act as catalyst to enhance the oxidation capacity of silver ions, resulting in a blue color burning and increase of the absorbance at 652 nm. Based on the above facts, a facile method is developed to qualitatively and quantitatively detect sulfide ions by naked eyes and UV–vis spectroscopy, respectively. The color changes of the detection system in the presence of nanomolar level of sulfide ions could be distinguished by naked-eyes, demonstrating the high sensitivity of the method. Highly sensitive detection of sulfide ions can be achieved in the range of 1.0 × 10−9 M to 8.0 × 10−8 M, with a detection limit of 0.2 nM. In addition, this method shows excellent selectivity toward sulfide ions detection and has been successfully applied to detect sulfide ions in tap water and lake water samples. Moreover, this method is simple without the preparation of nanomaterials and the need of complex readout instruments.
    Sensors and Actuators B Chemical 12/2015; 220:210-215. DOI:10.1016/j.snb.2015.05.066
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    ABSTRACT: A simple fluorescent assay for sensing bovine serum albumin (BSA) and calf thymus DNA (ctDNA) was developed based on the gold nanorods-based probe. Gold nanorods coated with mesoporous silica coated (Au@SiO2) which loading acridine orange (AO) was prepared by one-pot synthesis method. Interestingly, BSA is detected based on the quenching fluorescence signal while ctDNA is determined based on the enhanced fluorescence signal by the proposed method. Under the optimal conditions, the declined values of the fluorescent intensity of the biosensor are proportional to the BSA concentration in the range of 0.75–33.86 μmol/L. The limit of detection is 0.25 μmol/L. The enhanced values of the fluorescent intensity of the biosensor are linear with the ctDNA concentration in the range of 0.5–10 μg/mL, and the detection limit is 0.1667 μg/mL. The proposed method shows a good selectivity for BSA and ctDNA and can be applied to the determination of the analytes in real samples. The strategy of Au NRs@SiO2-AO complex as a novel fluorescent probe paves a new way to design fluorescent sensor.
    Sensors and Actuators B Chemical 12/2015; 220:302-308. DOI:10.1016/j.snb.2015.05.100
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    ABSTRACT: This paper presents a novel multilevel membraneless enzymatic biofuel cell. For the first time, we introduce the use of thin polyester films as flexible electrode substrates for a Glucose/O2 microfluidic biofuel cell. More specifically, we report a proof-of-concept based on a three dimensional (3D) microfluidic chip fabricated via rapid prototyping where two T-shaped microchannels are vertically stacked one above the other. Via the integration of two in-reservoirs, only three access ports are required and an even repartition of laminar flows is ensured within each microchannel. Both channels have gold electrodes patterned on their top and bottom walls. With four anodes/four cathodes having an individual area of 25 mm2, our structure is only 425 μm thick. Enzymatic reactions occur via the use of glucose oxidase and hexacyanoferrate flowing in the anolyte solution whereas freely suspended laccase and 2,2-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS) are introduced in the catholyte stream. Under a flow rate of 150 μL min−1 and with all anodes/cathodes connected in parallel, our structure can generate a maximum net power of 12.5 ± 0.05 μW. Connected to a voltage boost converter increasing the nominal output voltage to 3.1 V, we demonstrate that our proof-of-concept can already be exploited to supply electrical energy to a wireless sensor sending temperature measurements to a remote computer.
    Sensors and Actuators B Chemical 12/2015; 220:583-589. DOI:10.1016/j.snb.2015.05.099
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    ABSTRACT: Aberrant DNA methylation, which is caused by the abnormal level of DNA methyltransferase (MTase), has been considered associated with a growing number of human diseases. Although there are various methods paying close attention to DNA methyltransferase (MTase) detection, most of them are generally complex and expensive. Here, a simple electrochemical strategy for sensitive detection of DNA methyltransferase (MTase) and inhibitor screening based on DpnI digestion triggering the formation of G-quadruplex DNAzymes has been developed. In this paper, a probe richness of guanine (G) was first self-assembled on the surface of the electrode through Au–S bond and then hybridized with the complementary DNA. Without DNA methylation, G-quadruplex DNAzymes cannot be formed due to the double helix structure and a weak electrochemical response can be observed. On the contrary, an obvious enhancement of the electrochemical response can be achieved after the cleavage of the methylated double-strand DNA by DpnI since G-quadruplex DNAzymes can be obtained, which catalyze the oxidation of hydroquinone by H2O2 with the assistance of the cofactor hemin. This method is under a detection limit of 0.96 U/mL and can monitor the change of DNA methylation level selectively. Moreover, RG108 was selected as a representative inhibitor for studying the inhibition activity of DNA MTase.
    Sensors and Actuators B Chemical 12/2015; 220. DOI:10.1016/j.snb.2015.05.058
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    ABSTRACT: Room-temperature ionic liquids (RTILs) are promising for use in many industries due to their unique properties, including wide electrochemical windows, low vapor pressures, high ionic conductivities, and chemical and thermal stability. All of these properties require high RTIL purity, and achieving this high purity is a major driver of RTIL manufacturing costs. Continuous flow processes to synthesize highly pure RTILs at a reduced cost have been developed, but due to exothermic synthesis reactions and temperature dependent reaction rates, these processes require real-time control. An ultraviolet LED based optical sensor has been designed to measure RTIL purity at millisecond sampling rates using a liquid flow cell. The sensor is demonstrated by measuring 1-methylimidazole (MIM) concentration in 1-ethyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide ([EMIM][TFSI]). Sensor results are compared against spectroscopic measurements with good agreement.
    Sensors and Actuators B Chemical 12/2015; 220. DOI:10.1016/j.snb.2015.05.097