Molecular Biology and Evolution (MOL BIOL EVOL)

Publisher: Molecular Biology and Evolution Society; American Society of Naturalists; Society for the Study of Evolution, Oxford University Press (OUP)

Journal description

Molecular Biology and Evolution (MBE) is devoted to the interdisciplinary science between molecular biology and evolutionary biology. MBE emphasizes experimental papers, but theoretical papers are also published if they have a solid biological basis. Although this journal is primarily for original papers, review articles and book reviews are also published. MBE is an appropriate outlet for the examination of molecular evolutionary processes and patterns, and the testing of evolutionary hypotheses with molecular data. MBE is not an appropriate outlet for purely taxonomic treatments and the detailing of systematic issues. Published by the Society for Molecular Biology and Evolution.

Current impact factor: 14.31

Impact Factor Rankings

2015 Impact Factor Available summer 2015
2013 / 2014 Impact Factor 14.308
2012 Impact Factor 10.353
2011 Impact Factor 5.55
2010 Impact Factor 5.51
2009 Impact Factor 9.872
2008 Impact Factor 7.28
2007 Impact Factor 6.438
2006 Impact Factor 6.726
2005 Impact Factor 6.233
2004 Impact Factor 6.355
2003 Impact Factor 6.05
2002 Impact Factor 5.271
2001 Impact Factor 5.357
2000 Impact Factor 5.298
1999 Impact Factor 4.983
1998 Impact Factor 5.291
1997 Impact Factor 5.249
1996 Impact Factor 5.969
1995 Impact Factor 5.399
1994 Impact Factor 5.024
1993 Impact Factor 3.902
1992 Impact Factor 3.737

Impact factor over time

Impact factor

Additional details

5-year impact 11.22
Cited half-life 6.30
Immediacy index 1.56
Eigenfactor 0.10
Article influence 4.05
Website Molecular Biology and Evolution website
Other titles Molecular biology and evolution, MBE
ISSN 0737-4038
OCLC 9364605
Material type Periodical, Internet resource
Document type Journal / Magazine / Newspaper, Internet Resource

Publisher details

Oxford University Press (OUP)

  • Pre-print
    • Author can archive a pre-print version
  • Post-print
    • Author cannot archive a post-print version
  • Restrictions
    • 12 months embargo
  • Conditions
    • Pre-print can only be posted prior to acceptance
    • Pre-print on pre-print servers
    • Pre-prints that are accepted will be required to select Oxford Open when accepted
    • Pre-print must be accompanied by set statement (see link) and state of article review
    • Pre-print must match current version under consideration
    • Pre-print must be ammended with a a link to published version
    • Post-print in Institutional repositories or Central repositories
    • Publisher's version/PDF cannot be used
    • Published source must be acknowledged
    • Must link to publisher version
    • Set phrase to accompany archived copy (see policy)
    • Eligible authors may deposit in OpenDepot
    • The publisher will deposit in PubMed Central on behalf of NIH authors
    • This policy is an exception to the default policies of 'Oxford University Press (OUP)'
  • Classification
    ​ yellow

Publications in this journal

  • Molecular Biology and Evolution 04/2015;
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    ABSTRACT: Across the great diversity of life, there are many compelling examples of parallel and convergent evolution - similar evolutionary changes arising in independently evolving populations. Parallel evolution is often taken to be strong evidence of adaptation occurring in populations that are highly constrained in their genetic variation. Theoretical models suggest a few potential factors driving the probability of parallel evolution, but experimental tests are needed. In this study, we quantify the degree of parallel evolution in fifteen replicate populations of Pseudomonas fluorescens evolved in five different environments that varied in resource type and arrangement. We identified repeat changes across multiple levels of biological organization from phenotype, to gene, to nucleotide, and tested the impact of (1) selection environment; (2) the degree of adaptation; and (3) the degree of heterogeneity in the environment on the degree of parallel evolution at the gene-level. We saw, as expected, that parallel evolution occurred more often between populations evolved in the same environment, however the extent of parallel evolution varied widely. The degree of adaptation did not significantly explain variation in the extent of parallelism in our system but number of available beneficial mutations correlated negatively with parallel evolution. In addition, degree of parallel evolution was significantly higher in populations evolved in a spatially-structured, multi-resource environment, suggesting that environmental heterogeneity may be an important factor constraining adaptation. Overall, our results stress the importance of environment in driving parallel evolutionary changes and point to a number of avenues for future work for understanding when evolution is predictable. © The Author 2015. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail:
    Molecular Biology and Evolution 03/2015; 32(6). DOI:10.1093/molbev/msv033
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    ABSTRACT: Although an increasing number of horizontal gene transfers (HGTs) have been reported in eukaryotes, experimental evidence for their adaptive value is lacking. Here, we report the recent transfer of a 158-kb genomic region between Torulaspora microellipsoides and Saccharomyces cerevisiae wine yeasts or closely related strains. This genomic region has undergone several rearrangements in S. cerevisiae strains, including gene loss and gene conversion between two tandemly duplicated FOT genes encoding oligopeptide transporters. We show that FOT genes confer a strong competitive advantage during grape must fermentation by increasing the number and diversity of oligopeptides that yeast can utilise as a source of nitrogen, thereby improving biomass formation, fermentation efficiency and cell viability. Thus, the acquisition of FOT genes has favoured yeast adaptation to the nitrogen-limited wine fermentation environment. This finding indicates that anthropic environments offer substantial ecological opportunity for evolutionary diversification through gene exchange between distant yeast species.
    Molecular Biology and Evolution 03/2015;
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    ABSTRACT: As humans migrated around the world, they came to inhabit environments that differ widely in the soil levels of certain micronutrients, including selenium (Se). Coupled with cultural variation in dietary practices, these migrations have led to a wide range of Se intake levels in populations around the world. Both excess and deficiency of Se in the diet can have adverse health consequences in humans, with severe Se deficiency resulting in diseases of the bone and heart. Se is required by humans mainly due to its function in selenoproteins, which contain the amino acid selenocysteine (Sec) as one of their constituent residues. To understand the evolution of the use of this micronutrient in humans we surveyed the patterns of polymorphism in all selenoprotein genes and genes involved in their regulation in 50 human populations. We find that SNPs from populations in Asia, particularly in populations living in the extreme Se-deficient regions of China, have experienced concerted shifts in their allele frequencies. Such differentiation in allele frequencies across genes is not observed in other regions of the world and is not expected under neutral evolution, being better explained by the action of recent positive selection. Thus, recent changes in the use and regulation of Se may harbour the genetic adaptations that helped humans inhabit environments that do not provide adequate levels of Se in the diet. © The Author 2015. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail:
    Molecular Biology and Evolution 03/2015; 32(6). DOI:10.1093/molbev/msv043
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    ABSTRACT: Initial studies of the archaeal phylogeny relied mainly on the analysis of the RNA component of the small subunit of the ribosome (SSU rRNA). The resulting phylogenies have provided interesting but partial information on the evolutionary history of the third domain of life because SSU rRNA sequences do not contain enough phylogenetic signal to resolve all nodes of the archaeal tree. Thus, many relationships, and especially the most ancient ones, remained elusive. Moreover, SSU rRNA phylogenies can be heavily biased by tree reconstruction artifacts. The sequencing of complete genomes allows using a variety of protein markers as an alternative to SSU rRNA. Taking advantage of the recent burst of archaeal complete genome sequences, we have carried out an in-depth phylogenomic analysis of this domain. We have identified 200 new protein families that, in addition to the ribosomal proteins and the subunits of the RNA polymerase, form a conserved phylogenetic core of archaeal genes. The accurate analysis of these markers combined with desaturation approaches shed new light on the evolutionary history of Archaea and reveals that several relationships recovered in recent analyses are likely the consequence of tree reconstruction artifacts. Among others, we resolve a number of important relationships, such as those among methanogens Class I, and we propose the definition of two new super-classes within the Euryarchaeota: 'Methanomada' and 'Diaforarchaea'. © The Author 2015. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail:
    Molecular Biology and Evolution 02/2015; 32(5). DOI:10.1093/molbev/msv015