Cell Biology International Reports (Cell Biol Int Rep)

Publisher: International Federation for Cell Biology, Wiley Open Access

Journal description

Discontinued in 1991. Continued by Cell Biology International (1065-6995).

Current impact factor: 0.00

Impact Factor Rankings

Additional details

5-year impact 0.00
Cited half-life 0.00
Immediacy index 0.00
Eigenfactor 0.00
Article influence 0.00
Website Cell Biology International Reports website
Other titles Cell biology international reports
ISSN 0309-1651
OCLC 2823639
Material type Periodical
Document type Journal / Magazine / Newspaper

Publisher details

Wiley Open Access

  • Pre-print
    • Archiving status unclear
  • Post-print
    • Author can archive a post-print version
  • Conditions
    • Creative Commons Attribution License
    • Authors retain copyright
    • On open access repositories and any website
    • Hosting site must incorporate publisher-supplied amendments or retractions issued
    • Published source must be acknowledged including article DOI
    • Articles published prior to 14 August 2012, are published under a Creative Commons Attribution Non-Commercial License or another License
    • Publisher's version/PDF may be used
    • All titles are open access journals
    • 'Wiley Open Access' is an imprint of 'Wiley'
  • Classification
    ​ blue

Publications in this journal

  • Ciba Foundation Symposium 66 - Human Genetics: Possibilities and Realities, 05/2008: pages 251 - 281; , ISBN: 9780470720486
  • Cell Biology International Reports 01/1999; 16:28-35.
  • [Show abstract] [Hide abstract]
    ABSTRACT: A few weeks after submission of this manuscript my colleague and dear friend, Professor Dr. Wolfgang Wille, died at the age of only 45 years. From one moment to another, this paper has become a dedication to his memory. I shall never forget him.
    Cell Biology International Reports 01/1993; 16(12):1247-50. DOI:10.1016/S0309-1651(06)80041-X
  • [Show abstract] [Hide abstract]
    ABSTRACT: Angiogenesis involved numerous interactions between extracellular matrix and endothelial cells which may exhibit changes in actin filament distribution. Using an in vitro model, capillary endothelial cells were grown in fibrin matrix containing fibronectin or hyaluronic acid. Actin filament distribution, nucleus localization and cell morphology were observed. Preliminary study showed the formation of tube-, branche- and capillary-like structures within fibrin. In the presence of both fibrin and fibronectin, cells with actin filament stress fibers were more spreading than those in fibrin. In the presence of hyaluronic acid, tubes were limited in extension into the fibrin. In addition, the study of co-localization of nucleus and actin filaments showed different cell behaviours. Migratory cells seem to arrange in parallel to each other and a capillary-like structure may be formed at the proximal extremity of this cell pattern.
    Cell Biology International Reports 01/1993; 16(12):1251-63. DOI:10.1016/S0309-1651(06)80042-1
  • [Show abstract] [Hide abstract]
    ABSTRACT: The origin of late endosomes - multivesicular bodies (MVBs) in the superficial cells of 16 and 17 embryonic old transitional epithelium of mouse urinary bladder was studied by electron microscopy, lectin labelling and HRP tracing. Analysis of hexagonally structured membrane particles, WGA, and RCA I binding sites revealed structural similarity between plasmalemma, fusiform vesicles and multivesicular bodies. Early endosomes are lined by symmetric unit membrane as well as by asymmetric thickened membrane regions. Multivesicular bodies and fusiform vesicles have asymmetric unit membranes. MVBs may be derived from primary endosomes as well as from fusiform vesicles in the cytoplasm.
    Cell Biology International Reports 01/1993; 16(12):1219-28. DOI:10.1016/S0309-1651(06)80038-X
  • Cell Biology International Reports 01/1993; 16(12):1265-6. DOI:10.1016/S0309-1651(06)80043-3
  • [Show abstract] [Hide abstract]
    ABSTRACT: Mixed cultures of fibroblasts with rat colon carcinoma cell lines were used to investigate the production of extracellular matrix glycoproteins. Tumoral cells were shown to influence their production in different ways depending on the cell clone (PROb cells which in vivo produce progressive tumors and REGb cells which produce regressive ones) but also on the relative proportions of stromal and tumoral cells. When fibroblasts were predominant, the REGb cells containing mixture produced higher levels of all protein studied as compared with the PROb cells containing system. When the situation was reversed in favor of tumoral cells, REGb cells containing cocultures still produced more fibronectin, laminin and undulin, but the difference with PROb ones was reduced. On the opposite, cocultures enriched with PROb cells made more entactin and SPARC and approximately equal amounts of tenascin.
    Cell Biology International Reports 01/1993; 16(12):1237-45. DOI:10.1016/S0309-1651(06)80040-8
  • [Show abstract] [Hide abstract]
    ABSTRACT: We have mapped the epitopes for nine monoclonal antibodies raised against the nucleolar protein fibrillarin of the slime mold Physarum polycephalum. This has been done using a combination of specific chemical and enzymatic cleavage, Western blotting and partial sequencing of fragments. Cleavage with cyanogen bromide reveals four prominent methionine cleavage sites within the protein. Western blotting shows that none of the monoclonal antibody epitopes are dependent on long range interactions. Eight highly-conserved epitopes are clustered in the carboxy terminal half of the protein, while a single less-conserved epitope (for monoclonal antibody P1G12) is located at the amino terminus and appears to lie within the Gly/DMA/Phe domain.
    Cell Biology International Reports 12/1992; 16(11):1119-31. DOI:10.1016/S0309-1651(05)80038-4
  • Cell Biology International Reports 12/1992; 16(11):1111-7. DOI:10.1016/S0309-1651(05)80037-2
  • [Show abstract] [Hide abstract]
    ABSTRACT: The influence of maternal nicotine exposure (1 mg/kg body mass/day) during pregnancy and lactation on energy metabolism of lung tissue of neonatal rats were investigated. The glucose turnover of the lung tissue of the neonatal rats exposed to nicotine via the placenta and mother's milk was 86.4% higher than that of the controls. Glycolysis was however suppressed by 22.7% (P < 0.01). The adenine nucleotide pool (ATP+ADP+AMP) was 32.8% higher for the lungs of the 3 week old neonates exposed to nicotine than that of the control rat lung. After 4 weeks of nicotine withdrawal glycolysis of those animals exposed to nicotine were still inhibited to the same extent than during exposure. The adenine nucleotide pool was 69.95% higher than that of the controls. It is proposed that the inhibition of glycolysis was due to the high ATP/ADP ratio of the lungs of the nicotine exposed rats.
    Cell Biology International Reports 12/1992; 16(12):1229-36. DOI:10.1016/S0309-1651(06)80039-1
  • [Show abstract] [Hide abstract]
    ABSTRACT: The Amoeboflagellate Transformation (AFT) of Physarum polycephalum involves rapid changes in the cytoskeleton, cell shape and cell motility. Use of pharmacologic agents to probe the role of cytoskeletal elements in the AFT are impeded because the transforming cells are very sensitive to such commonly-used drug solvents as DMSO. The anti-microtubule agent tubulozole is found to disrupt, rapidly and transiently, the AFT, inhibiting flagella formation, cell elongation and the arrangement of microtubules and microfilaments. Cells recover quickly, possibly due to precipitation of the drug; the reappearance of normal arrays of microfilaments and cytoplasmic microtubules lags behind flagella formation.
    Cell Biology International Reports 12/1992; 16(11):1055-60. DOI:10.1016/S0309-1651(05)80029-3
  • [Show abstract] [Hide abstract]
    ABSTRACT: DNA polymerase alpha and DNA polymerase alpha--primase complex of Physarum polycephalum were purified by rapid methods, and antibodies were raised against the complex. In crude extracts, immune-reactive polypeptides of 220 kDa, 180 kDa, 150 kDa, 140 kDa, 110 kDa, 86 kDa, 57 kDa and 52 kDa were identified. The structural relationships between the 220 kDa, 110 kDa and 140 kDa (the most abundant form) was investigated by peptide mapping. The 140 kDa form was active DNA polymerase alpha. The 57 kDa and the 52 kDa polypeptides were identified as primase subunits by auto-catalytic labelling. In amoebae, the immune-reactive 140 kDa polypeptide was replaced by a 135 kDa active DNA polymerase alpha.
    Cell Biology International Reports 12/1992; 16(11):1047-53. DOI:10.1016/S0309-1651(05)80028-1
  • [Show abstract] [Hide abstract]
    ABSTRACT: The development of an amoeba into a plasmodium involves extensive changes in cellular organisation and gene expression. The genetic basis of a number of recessive mutations that block plasmodium development has been elucidated. The stage at which development becomes abnormal has been determined for all the mutants, as has the terminal phenotype. In order to investigate the changes in gene expression that accompany plasmodium development, a cDNA library has been made using RNA isolated from cell populations in which development was occurring.
    Cell Biology International Reports 12/1992; 16(11):1083-90. DOI:10.1016/S0309-1651(05)80033-5
  • [Show abstract] [Hide abstract]
    ABSTRACT: Regulation of expression of 3 isocoding genes of the actin gene family of Physarum was analyzed with gene specific probes. At steady state level, ardB and ardC seem to fluctuate coordinately during the cell cycle; ardA transcripts were not detected. Nuclear run-on assays suggested different transcription rates for ardB and ardC. Late G2 phase nuclei revealed hybridization signlas of in vitro synthesized RNA to ardA sequences, indicating transient activation of this late replicating gene.
    Cell Biology International Reports 11/1992; 16(11):1077–1081. DOI:10.1016/S0309-1651(05)80032-3
  • [Show abstract] [Hide abstract]
    ABSTRACT: Specific enzyme activities of thymidine kinase (TK) and deoxy-cytidine kinase (dCK) increase sharply at the onset of synchronous mitosis in macroplasmodia of Physarum polycephalum. They reach a maximum in early S-phase (Physarum lacks a G1 period) and decline to a minimum in late G2. Partial inhibition of DNA synthesis with methotrexate (MTX) or hydroxyurea (HU) retards the onset of the next mitosis and provokes a superinduction of both enzymes, with dCK responding stronger than TK. The temporal pattern observed suggests that the drugs interfere with the postmitotic down-regulation of enzyme expression, possibly due to alterations of the chromatin structure. Moderate inhibition of DNA synthesis still permits the appearance of (delayed) mitoses associated with peaks of enzyme activity at elevated levels. On the other hand, stronger inhibition completely suppresses the onset of mitosis and keeps the enzyme activities at an elevated level without further oscillations. The timing mechanism of periodic enzyme induction therefore appears to be functionally linked to the mitotic signal and does not persist under a stringent DNA block.
    Cell Biology International Reports 11/1992; 16(11-16):1159-1168. DOI:10.1016/S0309-1651(05)80043-8
  • [Show abstract] [Hide abstract]
    ABSTRACT: Changes on collagen synthetic activity of cultured arterial smooth muscle cells of rabbits induced with purified platelet-derived growth factor (PDGF) were examined. PDGF treatment (final concentration was 5 units/ml) decreased the total collagen synthesis per cell, while the rate of collagen synthesis against total protein synthesis was raised by PDGF. Type analysis of collagen revealed substantial reduction of type IV collagen and relative increase of type V collagen in the PDGF-treated cells. By immunofluorescence study using anti-type IV collagen antibody, the lacework fluorescence was decreased with PDGF supplement. These findings indicate that PDGF induces the decrease of type IV collagen synthesis with the simultaneous diminution of basement membrane formation probably in association with phenotypic modulation of smooth muscle cells.
    Cell Biology International Reports 11/1992; 16(10):1015-22. DOI:10.1016/S0309-1651(06)80054-8
  • [Show abstract] [Hide abstract]
    ABSTRACT: High specific activity (20 Ci/mmol) tritiated hydralazine (3Hyd) distribution in isolated, cultured vascular muscle cells was determined to identify the sites of Hyd binding. 3Hyd dose-dependently bound to extracellular protein and to the area of organelles which secrete these proteins. Increased extracellular binding after Hyd pre-exposure suggests new binding sites may be exacerbated as a result of Hyd interactions. These experiments suggest a potentially important feature of the mechanism of action of this directly acting vasodilator.
    Cell Biology International Reports 11/1992; 16(10):1023-39. DOI:10.1016/S0309-1651(06)80055-X