International Journal of Obesity Impact Factor & Information

Publisher: International Association for the Study of Obesity, Nature Publishing Group

Journal description

Multi-disciplinary forum for research describing: basic clinical and applied studies in biochemistry, physiology, genetics and nutrition, molecular, metabolic, psychological and epidemiological aspects of obesity and related disorders.

Current impact factor: 5.00

Impact Factor Rankings

2015 Impact Factor Available summer 2016
2014 Impact Factor 5.004
2013 Impact Factor 5.386
2012 Impact Factor 5.221
2011 Impact Factor 4.691
2010 Impact Factor 5.125
2009 Impact Factor 4.343
2008 Impact Factor 3.64
2007 Impact Factor 3.56
2006 Impact Factor 4.055
2005 Impact Factor 4.482
2004 Impact Factor 3.459
2003 Impact Factor 2.794
2002 Impact Factor 2.363
2001 Impact Factor 2.196
2000 Impact Factor 2.982
1999 Impact Factor 3.199
1998 Impact Factor 3.003
1997 Impact Factor 2.476
1996 Impact Factor 1.759
1995 Impact Factor 1.832
1994 Impact Factor 1.568
1993 Impact Factor 1.776
1992 Impact Factor 1.607

Impact factor over time

Impact factor

Additional details

5-year impact 5.28
Cited half-life 8.60
Immediacy index 1.11
Eigenfactor 0.03
Article influence 1.82
Website International Journal of Obesity website
Other titles International journal of obesity
ISSN 0307-0565
OCLC 26074170
Material type Periodical, Internet resource
Document type Journal / Magazine / Newspaper, Internet Resource

Publisher details

Nature Publishing Group

  • Pre-print
    • Author can archive a pre-print version
  • Post-print
    • Author cannot archive a post-print version
  • Restrictions
    • 6 months embargo
  • Conditions
    • Authors retain copyright
    • Published source must be acknowledged and DOI cited
    • Must link to publisher version
    • Publisher's version/PDF cannot be used
    • On author's personal website and institutional repository
    • If funding agency rules apply, authors may post authors version to their relevant funding body's archive, 6 months after publication
    • This policy is an exception to the default policies of 'Nature Publishing Group'
  • Classification

Publications in this journal

  • M Price · M Lee · S Higgs ·
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    ABSTRACT: Background/objectives: The relationship between response inhibition and obesity is currently unclear. This may be because of inconsistencies in methodology, design limitations and the use of narrow samples. In addition, dietary restraint has not been considered, yet restraint has been reported to moderate performance on behavioural tasks of response inhibition. The aim of this study was to investigate performance on both a food-based and a neutral stimuli go/no-go task, which addresses current design limitations, in lean and overweight/obese adults. The moderating role of dietary restraint in the relationship between body composition, response inhibition and snack intake was also measured. Subjects/methods: Lean and overweight/obese, males and females (N=116) completed both a food-based and neutral category control go/no-go task, in a fully counterbalanced repeated-measures design. A bogus taste-test was then completed, followed by a self-report measure of dietary restraint. Results: PROCESS moderated-mediation analysis showed that overweight/obese, compared to lean, participants made more errors on the food-based (but not the neutral) go/no-go task, but only when they were low in dietary restraint. Performance on the food-based go/no-go task predicted snack intake across the sample. Increased intake in the overweight, low restrainers was fully mediated by increased errors on the food-based (but not the neutral) go/no-go task. Conclusions: Distinguishing between high and low restrained eaters in the overweight/obese population is crucial in future obesity research incorporating food-based go/no-go tasks. Poor response inhibition to food cues predicts overeating across weight groups, suggesting weight loss interventions and obesity prevention programmes should target behavioural inhibition training in such individuals.International Journal of Obesity accepted article preview online, 23 November 2015. doi:10.1038/ijo.2015.235.
    International Journal of Obesity 11/2015; DOI:10.1038/ijo.2015.235
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    ABSTRACT: Background/objectives: Pregnancy is accompanied by fat gain and insulin resistance. Changes in adipose tissue morphology and function during pregnancy and factors contributing to gestational insulin resistance are incompletely known. We sought to characterize adipose tissue in trimesters 1 and 3 (T1/T3) in normal weight (NW) and obese pregnant women, and identify adipose tissue-related factors associated with gestational insulin resistance. Subjects/methods: Twenty-two NW and 11 obese women were recruited early in pregnancy for the Pregnancy Obesity Nutrition and Child Health study. Examinations and sampling of blood and abdominal adipose tissue were performed longitudinally in T1/T3 to determine fat mass (air-displacement plethysmography); insulin resistance (homeostasis model assessment of insulin resistance, HOMA-IR); size, number, and lipolytic activity of adipocytes; and adipokine release and density of immune cells and blood vessels in adipose tissue. Results: Fat mass and HOMA-IR increased similarly between T1 and T3 in the groups; all remained normoglycemic. Adipocyte size increased in NW women. Adipocyte number was not influenced, but proportions of small and large adipocytes changed oppositely in the groups. Lipolytic activity and circulating adipocyte fatty acid-binding protein increased in both groups. Adiponectin release was reduced in NW women. Fat mass and the proportion of very large adipocytes were most strongly associated with T3 HOMA-IR by multivariable linear regression (R(2)=0.751, P<0.001). Conclusions: During pregnancy, adipose tissue morphology and function change comprehensively. NW women accumulated fat in existing adipocytes, accompanied by reduced adiponectin release. In comparison with the normal weight group, obese women had signs of adipocyte recruitment and maintained adiponectin levels. Body fat and large adipocytes may contribute significantly to gestational insulin resistance.International Journal of Obesity accepted article preview online, 13 November 2015. doi:10.1038/ijo.2015.232.
    International Journal of Obesity 11/2015; DOI:10.1038/ijo.2015.232
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    ABSTRACT: Background/Objectives The neurobiological mechanisms linking obesity to emotional distress remain largely undiscovered.
    International Journal of Obesity 10/2015; DOI:10.1038/ijo.2015.216
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    ABSTRACT: Objectives:To construct waist-to-height ratio (WC/Ht) reference values and centile curves for Japanese children and to compare these references with those from other countries.Methods:The 1978–1981 national survey data were used for reference and the 1992–1994 national survey data were used for validation. The former included 19 233 children, and the latter included 10 446 children, aged 6 to 18 years. Waist circumferences (WC) were measured at the level of maximum waist narrowing in girls, and at the level of the top of the iliac crest in boys. Age- and sex-specific reference curves were fitted with the LMS method. Cut-off points were arbitrarily set at 85th, 90th, 95th and 97th centiles, and compared with WC/Ht 0.50.Results:The proportion of children in whom WC/Ht exceeded 0.50 was 18.7% of boys and 1.9% of girls, whereas the proportion of children exceeding 90th centile was 42.4% for boys and 17.3% for girls. The reference values decreased with age in girls but varied by age without a clear trend in boys.Conclusions:The first reference values for WC/Ht are provided for Japanese youth based on the 1978–1981 national survey data. These curves are age- and sex-dependent, precluding the use of universal cut-off for WC/Ht of 0.50.International Journal of Obesity advance online publication, 3 November 2015; doi:10.1038/ijo.2015.203.
    International Journal of Obesity 10/2015; DOI:10.1038/ijo.2015.203
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    ABSTRACT: Inflammation, oxidative stress, and dysregulation of adipokines are thought to be pathophysiological mechanisms linking obesity to the development of insulin resistance and atherosclerosis. In adults, bariatric surgery reduces inflammation and oxidative stress, and beneficially changes levels of several adipokines, but little is known about post-surgical changes among adolescents. In two separate longitudinal cohorts we evaluated change from baseline of interleukin-6 (IL-6), tumor necrosis factor alpha (TNF-α), monocyte chemo-attractant protein-1 (MCP-1), oxidized LDL cholesterol (oxLDL), adiponectin, leptin, and resistin up to 12 months following elective laparoscopic roux en Y gastric bypass (RYGB) or vertical sleeve gastrectomy (VSG) surgery in adolescents with severe obesity. In cohort 1, which consisted of 39 adolescents (mean age 16.5±1.6; 29 females) undergoing either RYGB or VSG, IL-6 (baseline: 2.3±3.4 pg/ml vs 12 months: 0.8±0.6 pg/ml, P<0.01), leptin (baseline: 178±224 ng/ml vs 12 months: 41.4±31.9 ng/ml, P<0.001), and oxLDL (baseline: 41.6±11.6 U/l vs 12 months: 35.5±11.1 U/l, P=0.001) significantly decreased and adiponectin significantly increased (baseline: 5.4±2.4 μg/ml vs 12 months: 13.5±8.9 μg/ml, P<0.001). In cohort 2, which consisted of 13 adolescents (mean age 16.5±1.6 years; 10 females) undergoing RYGB, results were similar: IL-6 (baseline: 1.7±0.9 pg/ml/ml vs 12 months: 0.4±0.9 pg/ml, P<0.05) and leptin (baseline: 92.9±31.3 ng/ml vs 12 months: 37.3±33.4 ng/ml, P<0.001) significantly decreased and adiponectin significantly increased (baseline: 6.1±2.9 μg/ml vs 12 months: 15.4±8.0 μg/ml, P<0.001). When the cohorts were combined to evaluate changes at 12 months, oxLDL also significantly decreased (baseline: 39.8±16.7 U/l vs 12 months: 32.7±11.9 U/l, P=0.03). Bariatric surgery produced robust improvements in markers of inflammation, oxidative stress, and several adipokines among adolescents with severe obesity, suggesting potential reductions in risk for type 2 diabetes and cardiovascular disease.International Journal of Obesity accepted article preview online, 28 August 2015. doi:10.1038/ijo.2015.174.
    International Journal of Obesity 08/2015; DOI:10.1038/ijo.2015.174
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    ABSTRACT: Activation of Notch signaling pathologically enhances lipogenesis and gluconeogenesis in the liver causing non-alcoholic fatty liver disease (NAFLD) and diabetes. Delta-like 1 homolog (DLK1), an imprinted gene that can modulate adipogenesis and muscle development in mice, was found as an inhibitory regulator of Notch signaling. Therefore, we investigated the metabolic effect of exogenous DLK1 in vitro and in vivo. A soluble DLK1 peptide was generated with fusion between a human Fc fragment and extracellular domain of DLK1. Male db/db mice were randomly assigned to two groups: vehicle-treated and DLK1-treated group (25 mg/kg, intraperitoneal injection, twice a week for 4 weeks). Primary mice hepatocytes and HepG2 cells were used for in vitro experiments. After 4 weeks of DLK1 administration, hepatic triglyceride content and lipid droplets in liver tissues, as well as serum levels of liver enzymes, were markedly decreased in db/db mice. DLK1 treatment induced phosphorylation of AMPK and ACC and suppressed nuclear expression of SREBP-1c in the mouse liver or hepatocytes, indicating regulation of fatty acid oxidation and synthesis pathways. Furthermore, DLK1-treated mice showed significantly lower levels of fasting and random glucose, with improved glucose and insulin tolerance compared to the vehicle-treated group. Macrophage infiltration and proinflammatory cytokine levels in the epididymal fat were decreased in DLK1-treated db/db mice. Moreover, DLK1 suppressed glucose production from hepatocytes, which was blocked after co-administration of an AMPK inhibitor, compound C. DLK1-treated hepatocytes and mouse liver tissues showed lower PEPCK and G6Pase expression. DLK1 triggered AKT phosphorylation followed by cytosolic translocation of FOXO1 from the nucleus in hepatocytes. The present study demonstrated that exogenous administration of DLK1 reduced hepatic steatosis and hyperglycemia via AMPK activation in the liver. This result suggests that DLK1 may be a novel therapeutic approach for treating NAFLD and diabetes.International Journal of Obesity accepted article preview online, 28 August 2015. doi:10.1038/ijo.2015.173.
    International Journal of Obesity 08/2015; DOI:10.1038/ijo.2015.173
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    ABSTRACT: In response to luminal food stimuli during meals, enteroendocrine cells release gastrointestinal (GI) peptides that have long been known to control secretory and motor functions of the gut, pancreas and liver. Glucagon-like peptide-1 (GLP-1) has emerged as one of the most important GI peptides because of a combination of functions not previously ascribed to any other molecule. GLP-1 potentiates glucose-induced insulin secretion, suppresses glucagon release, slows gastric emptying and may serve as a satiation signal, although the physiological status of the latter function has not been fully established yet. Here we review the available evidence for intestinal GLP-1 to fulfill a number of established empirical criteria for assessing whether a hormone inhibits eating by eliciting physiological satiation in man and rodents.International Journal of Obesity accepted article preview online, 28 August 2015. doi:10.1038/ijo.2015.172.
    International Journal of Obesity 08/2015; DOI:10.1038/ijo.2015.172
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    ABSTRACT: Human adenovirus 36 (Adv36) increases adiposity and is more prevalent in overweight and obese children. Dietary intake in animal models is comparable regardless of Adv36 status. The effects of Adv36 on obesity treatment outcomes have not been clarified. The aim of the study is to investigate the pre-treatment dietary intake and the response to a 4-week in-patient weight management in 184 obese adolescent girls aged 13.0-17.9 years with respect to the presence of Adv36 antibodies. Evaluation of 3-day dietary records did not show any difference in daily intake of energy and essential nutrients between Adv36 antibody positive and negative girls. After the intervention Adv36 positive girls presented with significantly greater decrease of waist circumference (P=0.020), z-score of waist circumference (P=0.024), waist-to-hip ratio (P=0.007) and weight-to-height ratio (P=0.019) compared to Adv36 negative girls. On the contrary, the sum of four skinfolds decreased significantly more in Adv36 negative than in Adv36 positive individuals (P=0.013). Neither body fat percentage nor metabolic and hormonal parameters showed any significant relevance to Adv36 status in response to weight loss intervention. In conclusion energy restriction in Adv36 antibody positive girls was associated with greater decrease of abdominal obesity and preservation of subcutaneous fat tissue than in those antibody negative.International Journal of Obesity accepted article preview online, 25 August 2015. doi:10.1038/ijo.2015.167.
    International Journal of Obesity 08/2015; DOI:10.1038/ijo.2015.167
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    ABSTRACT: Background/Objective Weight misperception is common among adolescents with obesity, but it is not known whether weight perception is related to future weight gain. The objective of the study was to examine the prospective association between accurate weight perception versus weight misperception and weight change among youth who are overweight or obese.Subjects/Methods Using a subsample of The National Longitudinal Study of Adolescent to Adult Health Wave II cohort, we used linear regression modeling (adjusted for age, baseline BMI, parental education, household percent federal poverty level, depression, race, and ethnicity) to examine the prospective association between weight misperception (i.e., perceiving oneself to be under or normal weight) among 2738 overweight and obese youth and subsequent BMI change from Wave II (1996) to Wave IV (2008-2009). Mean age at baseline (Wave II) was 15.9 (0.1).ResultsFifty-seven percent of males and 80% of females accurately perceived themselves as overweight. In fully adjusted models, weight misperception was associated with less BMI gain among youth who were overweight and obese. Specifically, youth who perceived themselves to be at a healthy weight had lower BMI gains (males: β=-1.43, 95% CI=[-2.26, -0.60], P=0.001; females: β=-1.35, 95% CI=[-2.59, -0.11], P=0.035) from Wave II to IV relative to those who accurately perceived themselves as overweight or obese.Conclusions Contrary to commonly held assumptions, weight misperception among a non-clinical sample of youth who were overweight or obese predicted lower future weight gain. Efficacy of efforts to correct weight misperception should be rigorously examined to assess for both intended and unintended consequences.International Journal of Obesity accepted article preview online, 25 August 2015. doi:10.1038/ijo.2015.166.
    International Journal of Obesity 08/2015; DOI:10.1038/ijo.2015.166
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    ABSTRACT: Background: Obesity is a complex disease caused by the interplay of genetic and lifestyle factors, but identification of gene-lifestyle interactions in obesity has remained challenging. Few large-scale studies have reported use of genome-wide approaches to investigate gene-lifestyle interactions in obesity. Methods: In the PROMIS study, a cross-sectional study based in Pakistan, we calculated BMI variance estimates (square of the residual of inverse-normal transformed BMI z-score) in 14 131 participants and conducted genome-wide heterogeneity of variance analyses (GWHVA) for this outcome. All analyses were adjusted for age, age2, sex and genetic ancestry. Results: The GWHVA analyses yielded a genome-wide significance (P-value=3.1 × 10-8) association of the rs140133294 variant at FLJ33534 with BMI variance. In explicit tests of gene × lifestyle interaction, smoking was found to significantly modify the effect of rs140133294 on BMI (Pinteraction=0.0005), whereby the minor allele (T) was associated with lower BMI in current smokers, while positively associated with BMI in never-smokers. No interactions with physical activity were observed. Analyses of ENCODE data at the FLJ33534 locus revealed features indicative of open chromatin and high confidence DNA-binding motifs for several transcription factors, providing suggestive biological support for a mechanism of interaction. Conclusion: In summary, we have identified a novel interaction between smoking and variation at the FLJ33534 locus in relation to BMI in people from Pakistan.
    International Journal of Obesity 08/2015; 10.1038/ijo.2015.152. DOI:10.1038/ijo.2015.152