Actas luso-españolas de neurología, psiquiatría y ciencias afines

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2000 Impact Factor 0.302
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1998 Impact Factor 0.013

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Other titles Actas luso-españolas de neurología, psiquiatría y ciencias afines
ISSN 0300-5062
OCLC 7533539
Material type Periodical
Document type Journal / Magazine / Newspaper

Publications in this journal

  • [Show abstract] [Hide abstract]
    ABSTRACT: Use of BMT (bone marrow transplatation) has rapidly grown in the last few years. It extends to a variety of neoplastic illnesses and hematological malignancies. This procedure includes implicit appearance of many and important stressors, both physical and psychological, due to the illness and to chemotherapy treatments, among which the appearance and severe colateral effects during the stay in hospital has a special relevance. The need to consider the influency of predictive variables like, prior experiences, optimistic vs. pesimistic expectancies and the strategies of coping used in the adaptation through the treatment, are a central point in the study of the fluctuations of the different psychological responses and their interrelation with the physiology symtomatology which are present during the different phases of the process of BMT.
    Actas luso-españolas de neurología, psiquiatría y ciencias afines 09/2013; 26(2):130-8.
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    Actas luso-españolas de neurología, psiquiatría y ciencias afines 01/2002; 17(2):126-31.
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    ABSTRACT: The pharmacological treatment of serious mental disorders in the pregnancy, supposes a clinical dare by the possible repercussions on the fetus and the pregnancy: theratogenesis, perinatal syndrome or postnative sequels in the development. The electroconvulsive therapy (ECT) as much takes implicit a minimum risk for the mother as for the fetus and therefore, it must be located in the highest positions of the therapeutic decision trees. In the present article, are reviewed the consequences of the pharmacological treatment and the ECT in the serious mental disorders during the pregnancy. Is referenced to all of the pharmacological groups and with respect to the ECT: their indications, counterindications, complications and technical procedures advisables. Finally is reviewed the guide line for each syndromical group of psychiatric diseases.
    Actas luso-españolas de neurología, psiquiatría y ciencias afines 12/2000; 26(3):187-200.
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    ABSTRACT: We present the use of risperidone as a potentiation strategy of the serotonergic antidepressants in four patients suffering from refractory obsessive-compulsive disorder. There were an important improvement in three patients. Adding risperidone to serotonergic antidepressants causes complex interactions between serotonergic, dopaminergic and noradrenergic systems, that could lay to the clinical improvement. These and other similar cases make necessary controlled studies. Adding risperidone to serotonergic antidepressants in patients suffering from refractory obsessive-compulsive disorder might be an effective strategy with low risk for secondary effects and without the presence of tics or psychotic symptoms.
    Actas luso-españolas de neurología, psiquiatría y ciencias afines 11/1998; 26(6):399-402.
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    ABSTRACT: There are many recent epidemiological studies that find that intravenous drug users' (IDU's) performance in several measures of neuropsychological function are not the same than that of the general population, whether they are seropositive to HIV-1 infection or not. Consequently, it has been stated the need to establish appropriate norms for this population. The purpose of this study is to provide normative data on a battery of neuropsychological tests from a IDU group. This report provide normative data from a group of 116 IDU, on a battery of neuropsychological tests stratified by age group (mean = 30.9; SD = 4.5), and educational level (mean = 8; SD = 2.4). Comparisons between the means of the different groups according to age and education, and also with respect to sex are made. The analysis includes estimation of partial correlations between neuropsychological test scores and age and education. The analysis demonstrates that education is an important determinant of performance for most of these tests, while there are no differences in performance between the two age-groups. With respect to sex, females out-performed men on a measure of motor speed and coordination. This report provides norms that may be of use as a reference for clinical evaluation and research in drug user populations. It also emphasizes the need to establish normative data controlling for variables like educational level, from a population with special characteristics such as IDU population.
    Actas luso-españolas de neurología, psiquiatría y ciencias afines 11/1998; 26(6):363-70.
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    ABSTRACT: Selective serotonin reuptake inhibitors (SSRI) have demonstrated to be effective, well tolerated and relatively safe drugs in cases of overdosage. However, and related to the potentiation of the serotonergic transmission elicited by them, these drugs have been associated by some authors with the possibility of causing vascular complications. Serotonin is a vasoactive substance with complex actions on vessel wall as a result of its interaction with specific receptors existing at this level. We present the case of an adolescent girl who suffered a cerebral infarction after consuming a toxic dose of paroxetine and two other products, one of them containing caffedrine and theodrenaline, and the other one a phlebotonic agent. In connection with the possible pathophysiological mecanism the implied products as well as the serotonergic vascular receptors are briefly reviewed. Finally, a reference is made to Calls syndrome as a possible entity related to the unfortunate event suffered by the patient. As a conclusion risks of the combined pharmacotherapy, especially in cases of overdosage and in child and adolescent populations, are underlined.
    Actas luso-españolas de neurología, psiquiatría y ciencias afines 09/1998; 26(5):333-8.
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    ABSTRACT: In this work with the SPECT we tried to define the most possible the disfuntions that could exist in a group of patients with severe recurrent depression. The sample is compound for fifteen patients (2 men and 13 woman) diagnosed of recurrent depression according CIE-10 with equal distribution between melancholic depressions and depressions with psychotic symptoms congruents and not congruents with the state of mood. The mean age of the group is of 55.4 years. All the patients have been studied with de SPECT (Tc-HMPAO) during the first week of hospitalization. The severity of the depressive syndrome was studied with the questionnaire for depression of Beck and the state of anxiety was studied with the questionnaire of anxiety of Spielberger. All the patients were severes depressives and anxious according to the questionnaires. We appreciated disfunction, hypocaptation, in frontoorbital zones, well bilateral (mainly in recurrent depressions with psychotic symptoms) or only in the left frontal side (areas of Brodmann 10 and 11) mainly in recurrent melancholies. We also found that in almost all the patients existed hypocaptation in the left angular circunvolution (areas of Brodmann 37 and 39). In the recurrent melancholies the localization of the hypocaptation is fundamentally posterior parietotemporal in the left side. In the recurrent serious depressions the hypocaptation is located to prefrontal level with tendency to bilateral being and/or posterior parietotemporal left side, that in the melancholies the localization of the hypocaptation is fundamentally posterior parietotemporal in the left side and it could imply that when the severity clinic gets complicated with psychotic symptoms the hypocaptation is located in a bigger number of places (prefrontal and left posterior parietotemporal) in relation to what it happens in the melancholic depressions. It seems to exist relationship between depressive and anxious severity and localization of the hypocaptation.
    Actas luso-españolas de neurología, psiquiatría y ciencias afines 07/1998; 26(4):223-32.
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    ABSTRACT: A common idea is the that the patients with affective and anxiety disorders recover in a partial way their memories in function of their state. This particular fact can influence the remembrance of the upbringing so that the memory is facilitated for facts congruent with their current affects. The authors apply a questionnaire of upbringing (PBI) to a group of anxious and depressive patients at the beginning of the treatment and when the improvement has taken place. There are not variations for the punctuations in the scale of upbringing, which is invariant with the changes of the humour.
    Actas luso-españolas de neurología, psiquiatría y ciencias afines 07/1998; 26(4):241-6.
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    ABSTRACT: The prevalence of personality disorders in penal population was studied with two instruments, the classic MMPI and the recently published IPDE, authorized by the WHO for the diagnosis of personality disorders in both, DSM-IV and ICD-10 versions. A sample of 56 prisoners from a Spanish prison was studied, mean age 22, all male, 98% of them had never requested psychiatric help. The crimes most frequently committed were related to drug traffic and drug abuse (thefts, robberies, crimes against public health). There were also cases of homicide, homicide attempt, rape and kidnapping. 91% of the studied sample presented one or more personality disorders, being the most frequent: Antisocial (79%), Paranoid (52%) and Borderline (41%). The MMPI scales most frequently obtained were: Psychopathic deviation (59%), Paranoia (46%) and Schizophrenia (41%). There was a good clinical correlation between the IPDE and the MMPI results.
    Actas luso-españolas de neurología, psiquiatría y ciencias afines 05/1998; 26(3):151-4.
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    ABSTRACT: To determine the factors associated with the maintenance of HIV-related risk behaviours in opiate patients dependent and establish whether psychopathology and more specifically personality disorders are part of them. Cross-sectional study with descriptive and analytical elements. The inpatient Drug-Dependence Unit of the Psychiatry Department at the Hospital Clínico Universitario in Valencia, Spain. Study subjects (n = 110) were consecutive first admissions to the Drug-Dependence Unit. The following instruments were used a structured clinical history, a Questionnaire on HIV-related risk behaviours, the Symptom Checklist-90 (SCL-90), the Beck Depression Inventory (BDI), and the Structured Clinical Interview for DSM-III-R personality disorders (SCID-II). Patients who had HIV-related risk behaviours were younger (CI95% = 0.43-3.99) and showed a younger age of first heroin and cocaine use. An association was found between a maintenance of risk behaviours and a current cocaine dependence (OR = 2.39; CI95% = 1.04-5.48), a current benzodiazepine dependence (OR = 6.81; CI95% = 2.67-17.38) and being HIV positive (OR = 2.5; CI95% = 1.10-5.67). An association was also found between HIV-related risk behaviours and the number of prior drug-related hospital admissions. The maintenance of risk behaviours was associated with the presence of personality disorders (OR = 2.63; CI95% = 1.18-5.84) and particularly with the antisocial personality disorder (OR = 3.75; CI95% = 1.61-8.75). The logistic regression analysis showed that the existence of benzodiazepine dependence, cocaine dependence, antisocial personality disorder and the number of drug-related admissions classified correctly 81.08% of patients. The higher severity of patients that maintained HIV-related risk behaviours and the association found with personality disorders suggests the need of designing more efficient therapeutic strategies for a subpopulation of drug misuser that showing HIV-related risk behaviours.
    Actas luso-españolas de neurología, psiquiatría y ciencias afines 05/1998; 26(3):155-64.
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    ABSTRACT: Schizophrenia is a heterogeneous clinical syndrome and this variability may reflect differences in etiology and pathophysiology. Such heterogeneity could be responsible for the difficulties in research when all patients with schizophrenia are included in the same group. Subgroups of more clinical homogeneity are more likely to be homogeneous for the presumed pathophysiology of interest. Primary, enduring negative symptoms have been proposed to designate the deficit syndrome. The data obtained in the recent years and summarized in this review show that negative symptoms broadly defined are less effective for subgrouping schizophrenia and that the deficit syndrome is a different domain within schizophrenia.
    Actas luso-españolas de neurología, psiquiatría y ciencias afines 05/1998; 26(3):180-6.
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    ABSTRACT: Data from naturalistic studies have reported differences in the clinical use of antidepressants referring to the need for adjusting doses, treatment duration, tolerability and use of concomitant medication. These differences could be considered as an indicator of the effectiveness of antidepressants in clinical practice settings. It is a naturalistic, retrospective, observational study which objective is to evaluate and compare the pattern of antidepressant use (fluoxetine, fluvoxamine, paroxetine, sertraline, venlafaxine) and to establish if there is a relation between the different pattern of use and the effectiveness of them. A retrospective dataset of patients who initiated therapy on fluoxetine, fluvoxamine, paroxetine, sertraline, or venlafaxine with a follow-up period of 6 months was used. Information about clinical characteristics of patients and antidepressant pattern of use were collected. Pattern of antidepressant use were defined as: "initial doses", "upward dose titration", "augmentation strategy", "switching" and "early interruption of treatment". The efficacy of the therapy was assessed by the CGI-improvement. Fluoxetine was the antidepressant more associated with a statistical significance (p = 0.001) to an stable pattern of use (initial doses without upward dose titration, switching or augmentation). After controlling for other observed baseline characteristics, patients who remained on their initial antidepressant therapy, with a stable pattern of use were 1.61 times more likely than patients who had an adjustment to therapy to experience a treatment response. Patients who initiated treatment with sertraline or venlafaxine were 2.155 and 4.831 times less likely, respectively, to experience a response relative to patients who initiated therapy on fluoxetine. The need to upward dose titration, switching or augmentation in the treatment could be indicated a worse therapeutic control of the symptoms. Patients treated with fluoxetine are in a stable pattern of use more likely than patients in the other antidepressants, this fact is related with better global therapeutic results.
    Actas luso-españolas de neurología, psiquiatría y ciencias afines 03/1998; 26(2):75-81.
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    ABSTRACT: The different occurrence of Suicide depending on the rural/urban environment, as well as the interaction of this variable with others such as sex and age has given rise to a large quantity of investigations over the world. It was necessary to carry out in Spain an updated study of these characteristics. Our purpose is to work with the raw data referred to suicide in the two last Spanish Census years. 4,619 records of suicide are requested and obtained from the Spanish National Statistics Institute registered in the years 1981 and 1991. Adjusted rates by rural/urban environment, sex and age are established and compared to each other. Suicide rate in Spain is always higher in the cities that in the country, no matter be sex or the age group. However, there appears to be no continuous relationship between Suicide and the environment variable, since the large cities seem to confer a certain prevention. On the other hand, the feminine urban suicidal behaviour is becoming quantitatively more and more similar to those of men.
    Actas luso-españolas de neurología, psiquiatría y ciencias afines 03/1998; 26(2):111-5.
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    ABSTRACT: The epidemiological data of prevalence of mental disorders according to gender differences are controversial. We analysed the prevalence among men and women via a two-stage epidemiological community study using the GHQ-28 and the SCAN on the island of Formentera (Spain). There are no sex differences in total prevalence; nevertheless some significant differences are detected when data is analysed on specific disorders. Affective disorders, sleep disorders and neurotic and somatoform disorders are more prevalent among women, whereas men have more psychoactive substance use disorders. Comorbidity with medical illness are higher in women but differences are not significant. These findings suggest the need to standardise procedures and instruments in these kinds of studies. This is because one of the bias could be the difference in the number of disorders included in the instrument design used (in our study, sleep disorders and psychoactive substance use disorders were included and personality disorders were excluded.
    Actas luso-españolas de neurología, psiquiatría y ciencias afines 01/1998; 26(2):90-6.
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    ABSTRACT: Despite its high frequency and its severe financial, social and personal complications, compulsive buying is rarely described in the psychiatric literature. We reviewed all the published papers on this syndrome to describe its clinical features, epidemiology and response to drug or psychological treatment. Psychiatric comorbidity is also reviewed and nosologic implications are analyzed.
    Actas luso-españolas de neurología, psiquiatría y ciencias afines 01/1998; 26(4):264-72.
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    ABSTRACT: Alimentary restraint, cognitive variable related to eating behavior and obesity, is reportedly a valuable predictor for the development of therapeutic strategies. This paper addresses the relationship between maternal restraint and several psychological variables in their daughters (alexithymia, neuroticism, extraversion). From the study of 35 mother-daughter dyads it can be concluded that daughters of highly restrained mothers tend to present high scores in the Restraint scale of the Three Factor Eating Questionnaire of Stunkard and Messick, translated into Spanish and validated as Cuestionario de Conducta Alimentaria. Daughters of highle restrained mothers present also higher scores in the Neuroticism scale of the revised version of the Eysenck Personality Questionnaire. Daughters of mothers with low Restraint scores are in average higher than those of their mothers, although lower than those belonging to daughters of highle restrained mothers. Previous observations on the positive correlation between Disinhibition and Hunger of the Three Factor Eating Questionnaire are confirmed. These results add an additional risk factor for obesity (mothers with high Restraint) and contribute to delineate a set of psychometric indicators which might be useful in the diagnosis and prognosis of eating and body weight disorders.
    Actas luso-españolas de neurología, psiquiatría y ciencias afines 01/1998; 26(5):303-8.