Actas luso-españolas de neurología, psiquiatría y ciencias afines

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2015 Impact Factor Available summer 2016
2000 Impact Factor 0.302
1999 Impact Factor 0.146
1998 Impact Factor 0.013

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Other titles Actas luso-españolas de neurología, psiquiatría y ciencias afines
ISSN 0300-5062
OCLC 7533539
Material type Periodical
Document type Journal / Magazine / Newspaper

Publications in this journal

  • [Show abstract] [Hide abstract]
    ABSTRACT: Use of BMT (bone marrow transplatation) has rapidly grown in the last few years. It extends to a variety of neoplastic illnesses and hematological malignancies. This procedure includes implicit appearance of many and important stressors, both physical and psychological, due to the illness and to chemotherapy treatments, among which the appearance and severe colateral effects during the stay in hospital has a special relevance. The need to consider the influency of predictive variables like, prior experiences, optimistic vs. pesimistic expectancies and the strategies of coping used in the adaptation through the treatment, are a central point in the study of the fluctuations of the different psychological responses and their interrelation with the physiology symtomatology which are present during the different phases of the process of BMT.
    Actas luso-españolas de neurología, psiquiatría y ciencias afines 09/2013; 26(2):130-8.
  • Actas luso-españolas de neurología, psiquiatría y ciencias afines 01/2002; 17(2):126-31.
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    ABSTRACT: The pharmacological treatment of serious mental disorders in the pregnancy, supposes a clinical dare by the possible repercussions on the fetus and the pregnancy: theratogenesis, perinatal syndrome or postnative sequels in the development. The electroconvulsive therapy (ECT) as much takes implicit a minimum risk for the mother as for the fetus and therefore, it must be located in the highest positions of the therapeutic decision trees. In the present article, are reviewed the consequences of the pharmacological treatment and the ECT in the serious mental disorders during the pregnancy. Is referenced to all of the pharmacological groups and with respect to the ECT: their indications, counterindications, complications and technical procedures advisables. Finally is reviewed the guide line for each syndromical group of psychiatric diseases.
    Actas luso-españolas de neurología, psiquiatría y ciencias afines 12/2000; 26(3):187-200.
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    ABSTRACT: We present the use of risperidone as a potentiation strategy of the serotonergic antidepressants in four patients suffering from refractory obsessive-compulsive disorder. There were an important improvement in three patients. Adding risperidone to serotonergic antidepressants causes complex interactions between serotonergic, dopaminergic and noradrenergic systems, that could lay to the clinical improvement. These and other similar cases make necessary controlled studies. Adding risperidone to serotonergic antidepressants in patients suffering from refractory obsessive-compulsive disorder might be an effective strategy with low risk for secondary effects and without the presence of tics or psychotic symptoms.
    Actas luso-españolas de neurología, psiquiatría y ciencias afines 11/1998; 26(6):399-402.
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    ABSTRACT: In this work with the SPECT we tried to define the most possible the disfuntions that could exist in a group of patients with severe recurrent depression. The sample is compound for fifteen patients (2 men and 13 woman) diagnosed of recurrent depression according CIE-10 with equal distribution between melancholic depressions and depressions with psychotic symptoms congruents and not congruents with the state of mood. The mean age of the group is of 55.4 years. All the patients have been studied with de SPECT (Tc-HMPAO) during the first week of hospitalization. The severity of the depressive syndrome was studied with the questionnaire for depression of Beck and the state of anxiety was studied with the questionnaire of anxiety of Spielberger. All the patients were severes depressives and anxious according to the questionnaires. We appreciated disfunction, hypocaptation, in frontoorbital zones, well bilateral (mainly in recurrent depressions with psychotic symptoms) or only in the left frontal side (areas of Brodmann 10 and 11) mainly in recurrent melancholies. We also found that in almost all the patients existed hypocaptation in the left angular circunvolution (areas of Brodmann 37 and 39). In the recurrent melancholies the localization of the hypocaptation is fundamentally posterior parietotemporal in the left side. In the recurrent serious depressions the hypocaptation is located to prefrontal level with tendency to bilateral being and/or posterior parietotemporal left side, that in the melancholies the localization of the hypocaptation is fundamentally posterior parietotemporal in the left side and it could imply that when the severity clinic gets complicated with psychotic symptoms the hypocaptation is located in a bigger number of places (prefrontal and left posterior parietotemporal) in relation to what it happens in the melancholic depressions. It seems to exist relationship between depressive and anxious severity and localization of the hypocaptation.
    Actas luso-españolas de neurología, psiquiatría y ciencias afines 07/1998; 26(4):223-32.
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    ABSTRACT: Schizophrenia is a heterogeneous clinical syndrome and this variability may reflect differences in etiology and pathophysiology. Such heterogeneity could be responsible for the difficulties in research when all patients with schizophrenia are included in the same group. Subgroups of more clinical homogeneity are more likely to be homogeneous for the presumed pathophysiology of interest. Primary, enduring negative symptoms have been proposed to designate the deficit syndrome. The data obtained in the recent years and summarized in this review show that negative symptoms broadly defined are less effective for subgrouping schizophrenia and that the deficit syndrome is a different domain within schizophrenia.
    Actas luso-españolas de neurología, psiquiatría y ciencias afines 05/1998; 26(3):180-6.
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    ABSTRACT: Data from naturalistic studies have reported differences in the clinical use of antidepressants referring to the need for adjusting doses, treatment duration, tolerability and use of concomitant medication. These differences could be considered as an indicator of the effectiveness of antidepressants in clinical practice settings. It is a naturalistic, retrospective, observational study which objective is to evaluate and compare the pattern of antidepressant use (fluoxetine, fluvoxamine, paroxetine, sertraline, venlafaxine) and to establish if there is a relation between the different pattern of use and the effectiveness of them. A retrospective dataset of patients who initiated therapy on fluoxetine, fluvoxamine, paroxetine, sertraline, or venlafaxine with a follow-up period of 6 months was used. Information about clinical characteristics of patients and antidepressant pattern of use were collected. Pattern of antidepressant use were defined as: "initial doses", "upward dose titration", "augmentation strategy", "switching" and "early interruption of treatment". The efficacy of the therapy was assessed by the CGI-improvement. Fluoxetine was the antidepressant more associated with a statistical significance (p = 0.001) to an stable pattern of use (initial doses without upward dose titration, switching or augmentation). After controlling for other observed baseline characteristics, patients who remained on their initial antidepressant therapy, with a stable pattern of use were 1.61 times more likely than patients who had an adjustment to therapy to experience a treatment response. Patients who initiated treatment with sertraline or venlafaxine were 2.155 and 4.831 times less likely, respectively, to experience a response relative to patients who initiated therapy on fluoxetine. The need to upward dose titration, switching or augmentation in the treatment could be indicated a worse therapeutic control of the symptoms. Patients treated with fluoxetine are in a stable pattern of use more likely than patients in the other antidepressants, this fact is related with better global therapeutic results.
    Actas luso-españolas de neurología, psiquiatría y ciencias afines 03/1998; 26(2):75-81.
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    ABSTRACT: The different occurrence of Suicide depending on the rural/urban environment, as well as the interaction of this variable with others such as sex and age has given rise to a large quantity of investigations over the world. It was necessary to carry out in Spain an updated study of these characteristics. Our purpose is to work with the raw data referred to suicide in the two last Spanish Census years. 4,619 records of suicide are requested and obtained from the Spanish National Statistics Institute registered in the years 1981 and 1991. Adjusted rates by rural/urban environment, sex and age are established and compared to each other. Suicide rate in Spain is always higher in the cities that in the country, no matter be sex or the age group. However, there appears to be no continuous relationship between Suicide and the environment variable, since the large cities seem to confer a certain prevention. On the other hand, the feminine urban suicidal behaviour is becoming quantitatively more and more similar to those of men.
    Actas luso-españolas de neurología, psiquiatría y ciencias afines 03/1998; 26(2):111-5.
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    ABSTRACT: The epidemiological data of prevalence of mental disorders according to gender differences are controversial. We analysed the prevalence among men and women via a two-stage epidemiological community study using the GHQ-28 and the SCAN on the island of Formentera (Spain). There are no sex differences in total prevalence; nevertheless some significant differences are detected when data is analysed on specific disorders. Affective disorders, sleep disorders and neurotic and somatoform disorders are more prevalent among women, whereas men have more psychoactive substance use disorders. Comorbidity with medical illness are higher in women but differences are not significant. These findings suggest the need to standardise procedures and instruments in these kinds of studies. This is because one of the bias could be the difference in the number of disorders included in the instrument design used (in our study, sleep disorders and psychoactive substance use disorders were included and personality disorders were excluded.
    Actas luso-españolas de neurología, psiquiatría y ciencias afines 01/1998; 26(2):90-6.
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    ABSTRACT: Despite its high frequency and its severe financial, social and personal complications, compulsive buying is rarely described in the psychiatric literature. We reviewed all the published papers on this syndrome to describe its clinical features, epidemiology and response to drug or psychological treatment. Psychiatric comorbidity is also reviewed and nosologic implications are analyzed.
    Actas luso-españolas de neurología, psiquiatría y ciencias afines 01/1998; 26(4):264-72.
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    ABSTRACT: Alimentary restraint, cognitive variable related to eating behavior and obesity, is reportedly a valuable predictor for the development of therapeutic strategies. This paper addresses the relationship between maternal restraint and several psychological variables in their daughters (alexithymia, neuroticism, extraversion). From the study of 35 mother-daughter dyads it can be concluded that daughters of highly restrained mothers tend to present high scores in the Restraint scale of the Three Factor Eating Questionnaire of Stunkard and Messick, translated into Spanish and validated as Cuestionario de Conducta Alimentaria. Daughters of highle restrained mothers present also higher scores in the Neuroticism scale of the revised version of the Eysenck Personality Questionnaire. Daughters of mothers with low Restraint scores are in average higher than those of their mothers, although lower than those belonging to daughters of highle restrained mothers. Previous observations on the positive correlation between Disinhibition and Hunger of the Three Factor Eating Questionnaire are confirmed. These results add an additional risk factor for obesity (mothers with high Restraint) and contribute to delineate a set of psychometric indicators which might be useful in the diagnosis and prognosis of eating and body weight disorders.
    Actas luso-españolas de neurología, psiquiatría y ciencias afines 01/1998; 26(5):303-8.
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    ABSTRACT: A patient with Cushing's syndrome presented psyquiatric manifestations that were diagnosed and treated before diagnosis of Cushing's syndrome. These manifestations were unspecific, unstable and they responded to etiologic treatment but they didn't to syntomatic treatment. This case demonstrates the importance to make a through search for organic factors when there are changes in physical appearance and psyquiatric features are changing through the evolution.
    Actas luso-españolas de neurología, psiquiatría y ciencias afines 01/1998; 26(6):395-8.
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    ABSTRACT: A total of 439 schizophrenic patients according to ICD-10 criteria was included in an open label postmarketing surveillance study to evaluate the efficiency of resperidone as maintenance treatment of the schizophrenic acute exacerbation. The efficiency of risperidone was assessed according the number of patients who responded to treatment, the duration of the hospitalization period an the decrease in the total score as well as in the different clusters of the Brief Psychiatric Rating Scale (BPRS) during the study period. A patient was considered as responder to treatment when a decrease of, at least, a 20% was achieved in the total BPRS score while being treated in monotherapy with risperidone. Safety was evaluated by the UKU subscale for neurological side effects and spontaneous reports. Patients were evaluated at baseline and weeks 1, 2, 6 and 12. Forty patients (9.1%) were excluded from the statistical analysis due to protocol violation. Eighty one patients (20.3%) dropped out due to lost for follow-up (n = 25; 6.3%), new hospitalization (n = 23; 5.8%), inefficacy (n = 12; 3%), side effects (n = 7; 1.8%) and others (n = 14; 3.5%). Risperidone was used at doses between 1.5 and 19 mg daily (mean dosage: 7.66 +/- 3.07 mg daily). The duration of the hospitalization when dosages of risperidone of less than 6 mg daily were used was 32.1 days. However, when higher dosages were used, the number of days in-hospital decreased (26.6 days at dosages between 6 and 9 mg daily and 25.3 days when dosages higher than 9 mg daily were used). There was a significant reduction, versus baseline, in the BPRS mean total scores as well as in it's different clusters. (positive symptoms, negative symptoms, anxiety/depression) from week one onwards. At week 1, 66.9% of the patients had an improvement (20% versus baseline in their BPRS total score. At the end of the study period, 93.2% of the patients had an improvement (20% in their BPRS total score. There was a significant reduction in the total UKU subscale for neurological side effects scores (p < 0.005) from week 1 onwards, as well as for the total score of the following symptoms: rigidity, hypokinesia, hyperkinesia tremor and akatysia.
    Actas luso-españolas de neurología, psiquiatría y ciencias afines 01/1998; 26(2):83-9.
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    ABSTRACT: The diagnosis of attention-deficit hyperactivity disorder among adolescents and adults, when they were not diagnosed during childhood, requires retrospective evaluation of the disorder. Parents are usually the best source of information about childhood conduct, but sometimes it is impossible to get them. The Wender-Utah Rating scale was developed as an aid in the retrospective evaluation of symptoms of attention-deficit, hyperactivity e impulsivity. The objective of this study was to determine the consistency and the validity of this questionnaire in Spanish. We evaluated medical students of the Universidad Autónoma de Puebla in Mexico with the Wender-Utah Questionnaire-Spanish. Some of them were evaluated again fifteen days later. We gave them the parents Rating Scale. We calculated the internal and the test-retest consistency and also the correlation between this Questionnaire and the Parents Rating Scale. We evaluated 946 students, 400 had the test-retest procedure and 532 returned the Parents Rating Scale. The internal consistency was superior to .80. The correlation symptoms of attention deficit, hyperactivity and impulsivity. The test-retest consistency was at least .80, for the evaluation of with the Parents Rating Scale were moderate. This Spanish translation of the Wender-Utah Questionnaire has adequate consistency and reproducibility so it can be used as a screening tool, also the validity of the different versions suggested can be evaluated.
    Actas luso-españolas de neurología, psiquiatría y ciencias afines 01/1998; 26(3):165-71.
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    ABSTRACT: Clinical observation: A 67-year-old female patient operated of a severe aortic esthenosis with extracorporeal circulation during cardiac surgery, developed psychiatric disturbances with excitement and delirium, being necessary internamtient in a psychiatric ward, a month later. The evolution was right after neuroleptic treatment and nowdays she's assimptomatic. We review what is wrote about posteparative cognitive dysfunction (POCD), being this a tardive presentation case. We analize the definition, prevalence, etiology, pathofisiology, treatment and prevention since it is a reversible surgery complication but if it isn't early diagnosed and treated, its morbidity and mortality can be high.
    Actas luso-españolas de neurología, psiquiatría y ciencias afines 01/1998; 26(4):273-6.
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    ABSTRACT: To determine the factors associated with the maintenance of HIV-related risk behaviours in opiate patients dependent and establish whether psychopathology and more specifically personality disorders are part of them. Cross-sectional study with descriptive and analytical elements. The inpatient Drug-Dependence Unit of the Psychiatry Department at the Hospital Clínico Universitario in Valencia, Spain. Study subjects (n = 110) were consecutive first admissions to the Drug-Dependence Unit. The following instruments were used a structured clinical history, a Questionnaire on HIV-related risk behaviours, the Symptom Checklist-90 (SCL-90), the Beck Depression Inventory (BDI), and the Structured Clinical Interview for DSM-III-R personality disorders (SCID-II). Patients who had HIV-related risk behaviours were younger (CI95% = 0.43-3.99) and showed a younger age of first heroin and cocaine use. An association was found between a maintenance of risk behaviours and a current cocaine dependence (OR = 2.39; CI95% = 1.04-5.48), a current benzodiazepine dependence (OR = 6.81; CI95% = 2.67-17.38) and being HIV positive (OR = 2.5; CI95% = 1.10-5.67). An association was also found between HIV-related risk behaviours and the number of prior drug-related hospital admissions. The maintenance of risk behaviours was associated with the presence of personality disorders (OR = 2.63; CI95% = 1.18-5.84) and particularly with the antisocial personality disorder (OR = 3.75; CI95% = 1.61-8.75). The logistic regression analysis showed that the existence of benzodiazepine dependence, cocaine dependence, antisocial personality disorder and the number of drug-related admissions classified correctly 81.08% of patients. The higher severity of patients that maintained HIV-related risk behaviours and the association found with personality disorders suggests the need of designing more efficient therapeutic strategies for a subpopulation of drug misuser that showing HIV-related risk behaviours.
    Actas luso-españolas de neurología, psiquiatría y ciencias afines 01/1998; 26(3):155-64.