Annual Review of Neuroscience (ANNU REV NEUROSCI)

Publisher: Annual Reviews

Journal description

Current impact factor: 19.32

Impact Factor Rankings

2015 Impact Factor Available summer 2016
2014 Impact Factor 19.32
2013 Impact Factor 22.66
2012 Impact Factor 20.614
2011 Impact Factor 25.737
2010 Impact Factor 26.756
2009 Impact Factor 24.822
2008 Impact Factor 26.405
2007 Impact Factor 26.077
2006 Impact Factor 28.533
2005 Impact Factor 24.184
2004 Impact Factor 23.143
2003 Impact Factor 30.167
2002 Impact Factor 24.091
2001 Impact Factor 27.152
2000 Impact Factor 26.676
1999 Impact Factor 22.605
1998 Impact Factor 23.023
1997 Impact Factor 21.952

Impact factor over time

Impact factor

Additional details

5-year impact 25.92
Cited half-life >10.0
Immediacy index 1.32
Eigenfactor 0.02
Article influence 13.62
Website Annual Review of Neuroscience website
Other titles Annual review of neuroscience
ISSN 0147-006X
OCLC 3505758
Material type Periodical, Internet resource
Document type Journal / Magazine / Newspaper, Internet Resource

Publisher details

Annual Reviews

  • Pre-print
    • Author can archive a pre-print version
  • Post-print
    • Author cannot archive a post-print version
  • Conditions
    • Must prominently state near the title of the preprint version that the article has been accepted for publication by Annual Reviews in a revised form
    • Authors may place their ePrint URL (free access to article) on one of author's personal website and one institutional repository only
    • Publisher copyright and source must be acknowledged
    • Must link to publisher version
    • Publisher last contacted on 03/09/2014
    • Publisher last reviewed on 10/08/2015
  • Classification
    ​ yellow

Publications in this journal

  • Annual Review of Neuroscience 01/2015; 38:127-49.
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    ABSTRACT: The basal ganglia are equipped with inhibitory and disinhibitory mechanisms that enable a subject to choose valuable objects and actions. Notably, a value can be determined flexibly by recent experience or stably by prolonged experience. Recent studies have revealed that the head and tail of the caudate nucleus selectively and differentially process flexible and stable values of visual objects. These signals are sent to the superior colliculus through different parts of the substantia nigra so that the animal looks preferentially at high-valued objects, but in different manners. Thus, relying on short-term value memories, the caudate head circuit allows the subject's gaze to move expectantly to recently valued objects. Relying on long-term value memories, the caudate tail circuit allows the subject's gaze to move automatically to previously valued objects. The basal ganglia also contain an equivalent parallel mechanism for action values. Such flexible-stable parallel mechanisms for object and action values create a highly adaptable system for decision making.
    Annual Review of Neuroscience 07/2014; 37(1):289-306. DOI:10.1146/annurev-neuro-071013-013924
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    ABSTRACT: Neural tube defects (NTDs), including spina bifida and anencephaly, are severe birth defects of the central nervous system that originate during embryonic development when the neural tube fails to close completely. Human NTDs are multifactorial, with contributions from both genetic and environmental factors. The genetic basis is not yet well understood, but several nongenetic risk factors have been identified as have possibilities for prevention by maternal folic acid supplementation. Mechanisms underlying neural tube closure and NTDs may be informed by experimental models, which have revealed numerous genes whose abnormal function causes NTDs and have provided details of critical cellular and morphological events whose regulation is essential for closure. Such models also provide an opportunity to investigate potential risk factors and to develop novel preventive therapies.
    Annual Review of Neuroscience 07/2014; 37(1):221-242. DOI:10.1146/annurev-neuro-062012-170354
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    ABSTRACT: Activity-dependent changes in the strength of synaptic connections are fundamental to the formation and maintenance of memory. The mechanisms underlying persistent changes in synaptic strength in the hippocampus, specifically long-term potentiation and depression, depend on new protein synthesis. Such changes are thought to be orchestrated by engaging the signaling pathways that regulate mRNA translation in neurons. In this review, we discuss the key regulatory pathways that govern translational control in response to synaptic activity and the mRNA populations that are specifically targeted by these pathways. The critical contribution of regulatory control over new protein synthesis to proper cognitive function is underscored by human disorders associated with either silencing or mutation of genes encoding proteins that directly regulate translation. In light of these clinical implications, we also consider the therapeutic potential of targeting dysregulated translational control to treat cognitive disorders of synaptic dysfunction.
    Annual Review of Neuroscience 07/2014; 37(1):17-38. DOI:10.1146/annurev-neuro-071013-014100
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    ABSTRACT: Visual motion cues provide animals with critical information about their environment and guide a diverse array of behaviors. The neural circuits that carry out motion estimation provide a well-constrained model system for studying the logic of neural computation. Through a confluence of behavioral, physiological, and anatomical experiments, taking advantage of the powerful genetic tools available in the fruit fly Drosophila melanogaster, an outline of the neural pathways that compute visual motion has emerged. Here we describe these pathways, the evidence supporting them, and the challenges that remain in understanding the circuits and computations that link sensory inputs to behavior. Studies in flies and vertebrates have revealed a number of functional similarities between motion-processing pathways in different animals, despite profound differences in circuit anatomy and structure. The fact that different circuit mechanisms are used to achieve convergent computational outcomes sheds light on the evolution of the nervous system.
    Annual Review of Neuroscience 07/2014; 37(1):307-327. DOI:10.1146/annurev-neuro-071013-013931
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    ABSTRACT: Recent advances in cell reprogramming enable investigators to generate pluripotent stem cells from somatic cells. These induced pluripotent cells can subsequently be differentiated into any cell type, making it possible for the first time to obtain functional human neurons in the lab from control subjects and patients with psychiatric disorders. In this review, we survey the progress made in generating various neuronal subtypes in vitro, with special emphasis on the characterization of these neurons and the identification of unique features of human brain development in a dish. We also discuss efforts to uncover neuronal phenotypes from patients with psychiatric disease and prospects for the use of this platform for drug development. Expected final online publication date for the Annual Review of Neuroscience Volume 37 is July 08, 2014. Please see for revised estimates.
    Annual Review of Neuroscience 06/2014; 37(1). DOI:10.1146/annurev-neuro-062012-170328
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    ABSTRACT: Although the prevalent view of emotion and decision making is derived from the notion that there are dual systems of emotion and reason, a modulatory relationship more accurately reflects the current research in affective neuroscience and neuroeconomics. Studies show two potential mechanisms for affect's modulation of the computation of subjective value and decisions. Incidental affective states may carry over to the assessment of subjective value and the decision, and emotional reactions to the choice may be incorporated into the value calculation. In addition, this modulatory relationship is reciprocal: Changing emotion can change choices. This research suggests that the neural mechanisms mediating the relation between affect and choice vary depending on which affective component is engaged and which decision variables are assessed. We suggest that a detailed and nuanced understanding of emotion and decision making requires characterizing the multiple modulatory neural circuits underlying the different means by which emotion and affect can influence choices. Expected final online publication date for the Annual Review of Neuroscience Volume 37 is July 08, 2014. Please see for revised estimates.
    Annual Review of Neuroscience 07/2013; 37(1). DOI:10.1146/annurev-neuro-071013-014119
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    ABSTRACT: Adult neurogenesis, a developmental process of generating functionally integrated neurons, occurs throughout life in the hippocampus of the mammalian brain and showcases the highly plastic nature of the mature central nervous system. Significant progress has been made in recent years to decipher how adult neurogenesis contributes to brain functions. Here we review recent findings that inform our understanding of adult hippocampal neurogenesis processes and special properties of adult-born neurons. We further discuss potential roles of adult-born neurons at the circuitry and behavioral levels in cognitive and affective functions and how their dysfunction may contribute to various brain disorders. We end by considering a general model proposing that adult neurogenesis is not a cell-replacement mechanism, but instead maintains a plastic hippocampal neuronal circuit via the continuous addition of immature, new neurons with unique properties and structural plasticity of mature neurons induced by new-neuron integration. Expected final online publication date for the Annual Review of Neuroscience Volume 37 is July 08, 2014. Please see for revised estimates.
    Annual Review of Neuroscience 07/2013; 37(1). DOI:10.1146/annurev-neuro-071013-014134
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    ABSTRACT: A hallmark of human language is that we combine lexical building blocks retrieved from memory in endless new ways. This combinatorial aspect of language is referred to as unification. Here we focus on the neurobiological infrastructure for syntactic and semantic unification. Unification is characterized by a high-speed temporal profile including both prediction and integration of retrieved lexical elements. A meta-analysis of numerous neuroimaging studies reveals a clear dorsal/ventral gradient in both left inferior frontal cortex and left posterior temporal cortex, with dorsal foci for syntactic processing and ventral foci for semantic processing. In addition to core areas for unification, further networks need to be recruited to realize language-driven communication to its full extent. One example is the theory of mind network, which allows listeners and readers to infer the intended message (speaker meaning) from the coded meaning of the linguistic utterance. This indicates that sensorimotor simulation cannot handle all of language processing. Expected final online publication date for the Annual Review of Neuroscience Volume 37 is July 08, 2014. Please see for revised estimates.
    Annual Review of Neuroscience 07/2013; 37(1). DOI:10.1146/annurev-neuro-071013-013847
  • Annual Review of Neuroscience 07/2010; 34(1):110301101035033. DOI:10.1146/annurev-neuro-061010-113742
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    ABSTRACT: The ability of distinct anatomical circuits to generate multiple behavioral patterns is widespread among vertebrate and invertebrate species. These multifunctional neuronal circuits are the result of multistable neural dynamics and modular organization. The evidence suggests multifunctional circuits can be classified by distinct architectures, yet the activity patterns of individual neurons involved in more than one behavior can vary dramatically. Several mechanisms, including sensory input, the parallel activity of projection neurons, neuromodulation, and biomechanics, are responsible for the switching between patterns. Recent advances in both analytical and experimental tools have aided the study of these complex circuits.
    Annual Review of Neuroscience 08/2008; 31(1):271-94. DOI:10.1146/annurev.neuro.31.060407.125552
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    ABSTRACT: More than three decades of research have demonstrated a role for hippocampal place cells in representation of the spatial environment in the brain. New studies have shown that place cells are part of a broader circuit for dynamic representation of self-location. A key component of this network is the entorhinal grid cells, which, by virtue of their tessellating firing fields, may provide the elements of a path integration-based neural map. Here we review how place cells and grid cells may form the basis for quantitative spatiotemporal representation of places, routes, and associated experiences during behavior and in memory. Because these cell types have some of the most conspicuous behavioral correlates among neurons in nonsensory cortical systems, and because their spatial firing structure reflects computations internally in the system, studies of entorhinal-hippocampal representations may offer considerable insight into general principles of cortical network dynamics.
    Annual Review of Neuroscience 08/2008; 31(1):69-89. DOI:10.1146/annurev.neuro.31.061307.090723