Acta medica Indonesiana

Publisher: Indonesian Society of Internal Medicine


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    Acta medica Indonesiana, Indonesian journal of medicine, Indonesian journal of internal medicine, IJIM
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    Journal / Magazine / Newspaper

Publications in this journal

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    ABSTRACT: Kaposi sarcoma defined as a multifocal lesion in mucocutaneous sites which has low-grade malignant potential. Kaposi sarcoma also commonly found in visceral organs. This malignancy is very popular among elderly men before the epidemic of HIV/AIDS in the decade of 1980-1990. Kaposi sarcoma known to be associated with immunodeficiency state as in HIV/AIDS patients. Nowdays, incidence of Kaposi sarcoma has decreased in developed countries in the era of Highly Active Antiretroviral Therapy (HAART), but still a big problem in resource-limited areas such as Sub-Saharan Africa.
    Acta medica Indonesiana 07/2014; 46(3):253-5.
  • Acta medica Indonesiana 07/2014; 46(3):173-4.
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    ABSTRACT: to obtain formulation of an effective and efficient strategy to overcome blood stream infection (BSI).
    Acta medica Indonesiana 07/2014; 46(3):209-16.
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    ABSTRACT: Transcatheter closure of perimembranous and muscular ventricular septal defect (VSD) has been performed widely and it has more advantages compare to surgery. However, transcatheter closure of residual VSD post operation of complex congenital heart disease is still challenging because of the complexity of anatomy and concern about device stability, so the operator should meticulously choose the most appropriate technique and device. We would like to report a case of transcatheter closure of residual VSD post Rastelli operation in a patient with double outlet right ventricle (DORV), sub-aortic VSD, severe infundibulum pulmonary stenosis (PS) and single coronary artery. The patient had undergone operations for four times, but he still had intractable heart failure that did not response to medications. On the first attempt. we closed theVSD using a VSD occluder, unfortunately the device embolized into the descending aorta, but fortunately we was able to snare it out. Then we decided to close the VSD using a patent ductus arteriosus (PDA occluder). On transesophageal echocardiography (TEE) and angiography evaluation, the device position was stable. Post transcatheter VSD closure, the patient clinical condition improved significantly and he could finally be discharged after a long post-surgery hospitalization. Based on this experience we concluded that the transcatheter closure of residual VSD in complex CHD using PDA occluder could be an effective alternative treatment.
    Acta medica Indonesiana 07/2014; 46(3):233-7.
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    ABSTRACT: The metal fume fever (MFF) is an inhalation fever syndrome in welders of galvanized steel, who join and cut metal parts using flame or electric arc and other sources of heat. Inhalation of certain freshly formed metal oxides produced from welding process can cause MFF as an acute self-limiting flulike illness. The most common cause of MFF is the inhalation of zinc oxide (ZnO). The inhalation of ZnO particles can provoke a number of clinical responses of which accompanied by changes in composition of bronchoalveolar lavage (BAL) fluid, including early increase in pro-inflammatory cytokines, inflammatory marker, and recruitment of inflammatory cells in the lungs. The MFF is characterized by fever, cough, sputing, wheezing, chest tightness, fatique, chills, fever, myalgias, cough, dyspnea, leukocytosis with a left shift, thirst, metallic taste, and salivations. The diagnosis of MFF diagnosis is based on clinical finding and occupational history. The symptoms resolved spontaneously. The treatment of MFF is entirely symptomatic, no specific treatment is indicated for MFF. The mainstay of management of MFF is prevention of sub-sequent exposure to harmful metals. Including public and physician awareness of MFF may help to reduce the occurrence of the disease.
    Acta medica Indonesiana 07/2014; 46(3):256-62.
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    ABSTRACT: to describe the profile of urinary infection (UI) and to analyze its risk factors and impacts.
    Acta medica Indonesiana 07/2014; 46(3):175-82.
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    ABSTRACT: to evaluate the effect of weight loss program on fat mass, visceral fat rating and metabolic syndrome markers in obese subjects with weight cycling.
    Acta medica Indonesiana 07/2014; 46(3):199-208.
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    ABSTRACT: to investigate the effects of Vitamin D calcitriol/1,25(OH)2D3 on NETosis in systemic lupus erythematosus (SLE) patients with hypovitamin D.
    Acta medica Indonesiana 07/2014; 46(3):189-98.
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    ABSTRACT: to test the precision and accuracy of a Digital Microcapillary instrument in measuring blood and plasma viscosity.
    Acta medica Indonesiana 07/2014; 46(3):226-32.
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    ABSTRACT: to describe non-spesific and specific immune response profile in Indonesian thalassemia major with and without splenectomy.
    Acta medica Indonesiana 07/2014; 46(3):217-25.
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    ABSTRACT: Pulmonary papillomatosis is an extremely rare variant of recurrent respiratory papillomatosis which is hard to treat, causes prolonged morbidity, and may transform into malignant disorder in several cases. Since the symptoms and radiologic findings are not specific, pulmonary papillomatosis is often being misdiagnosed. Although considered benign, pulmonary papillomatosis carries the most significant mortality. This is a case report of a 26 year old man who complained recurrent chronic cough, slight hemoptoe, occasional pleuritic pain, and several episodes of fever. He also had laryngeal papillomatosis and undergone serial endoscopic resection since his childhood. Multiple nodular and cavitary lesions, some with air fluid level, were found in both lung fields at chest radiography and scintigraphy. Diagnosis of pulmonary papillomatosis complicated with secondary infection was made after endoscopic and histologic study.
    Acta medica Indonesiana 07/2014; 46(3):238-43.
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    ABSTRACT: to explore the possibility of metformin protective effect on frailty syndrome.
    Acta medica Indonesiana 07/2014; 46(3):183-8.
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    ABSTRACT: Chronic kidney disease (CKD) is a worldwide health problem with a high incidence not only in western countries but also in Indonesia as well. The majority of patients with CKD died due to cardiovascular disease than CKD progression itself. In addition to traditional risk factors, cardiovascular disease in CKD might also due to non-traditional risk factors. Oxidative stress, as non-traditional risk factors, is not only able to explain the high incidence of cardiovascular disease in CKD, but also become a new target in therapeutic intervention. Oxidative stress in patients with CKD appears due to increased oxidant activity and decreased antioxidant system. Hemodialysis (HD) with the use of a cellulose and semi-cellulose membrane also contribute to increase oxidant that can activate the complement pathway. It stimulates inflammation that will further expand the production of oxidants and will ultimately increase oxidative stress.
    Acta medica Indonesiana 07/2014; 46(3):244-52.
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    ABSTRACT: Irritable bowel syndrome (IBS) is one of the most commonly encountered functional gastrointestinal disorders in the elderly. IBS is characterized by abdominal pain and altered bowel habits in the absence of specific organic pathology. The diagnosis of IBS usually depends primarily on established clinical criteria. Currently, Rome III criteria are the criteria of choice for defining IBS. However, aging itself is categorized as one of the alarm symptoms in the diagnosis of IBS that may warrant further investigation. Therefore, exclusion of organic diseases, using several investigations, is of paramount important in the older patients. In general, the treatment of IBS in the elderly is not different from the younger populations. However, greater caution needs to be considered before treating with drugs because of the altered risk-benefit profile in the elderly. Several studies have shown a strong relationship of IBS with psychiatric conditions. Thus, psychological treatments should also be considered in the management of IBS in the elderly.
    Acta medica Indonesiana 04/2014; 46(2):138-47.
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    ABSTRACT: A 51-year-old male came with thickening lesion in both legs since 2.5 years before presented. It started with small lesion and went larger. Before diagnosed, he was admitted to hospital due to unresolved headache. He complainted nausea, easily hungry, protrusion of both eyes without diplopia or diminution of vision, tremor, palpitation, and unintentional weight loss (25-30 kgs in a year). On examination, it was found that he was in thyrotoxic condition and has diffuse goiter. From skin examination he had raised hyperkeratotic, and waxy plaque like lesions over both pretibial region. Laboratory examination confirm for thyrotoxic with presumably Graves' disease. Thyroid scintigraphy showed diffused enlargement and increased uptake. Skin biopsy from the pretibial skin showed epidermis with vacuolar degeneration, partly spongiotic and hyperpigmentated, thickening basalis membrane, miksoid dermis and spreading chronic inflammatory cell in perivascular and periadneksal. It confirmed the diagnosis of myxedema hystologically. The patient was given methimazole with starting dose 3x10 mg and propanolol 2x10 mg. Methimazole was reduce according to lab result. The pretibial lesion was given Triamcinolone acetonide injection intralesion in both legs with starting dose 0.5 cc (preparation 10 mg/cc) per day and increased according to response. The patient was response to 1.5 cc per leg per day. The patient also given Kloderma Ointment used twice a day. The lesion now thinning, flat, and turn hyperpigmentation.
    Acta medica Indonesiana 04/2014; 46(2):148-9.
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    ABSTRACT: Aim: to identify the difference between coronary angiography in patients with acute coronary syndrome (ACS) aged 45 years and those aged >45 years. Methods: a total of 322 ACS patients who underwent coronary angiography in ICCU of Cipto Mangunkusumo Hospital, Jakarta between January 2008 and December 2012 were included in this study. The severity of coronary stenosis was determined by vessel score and coronary score. A significant vessel score was defined as a stenosis of coronary vessel of >70%. Patients were divided into two groups: those aged 45 years (72 cases) and those aged >45 years (250 cases). The statistical analysis was performed with Chi-square test for categorical data with two-unpaired groups and the t-test or Mann-Whitney for numerical data. Results: the highest distribution of 1-VD (single-vessel disease) patients was found the group of patients aged 45 years (43.1% vs 26.0%); while for 3-VD (triple-vessel disease) patients, the highest distribution was noticed in the group of patients aged >45 years (31.6% vs 18.1%). The stenosis score was lower in patients aged 45 years compared those aged >45 years (median stenosis score 4 vs 8), p<0.001. Atherosclerosis was found most common for the left anterior descending artery in both age groups (65.3% and 74.0%). However, there was less significant stenosis lesion for the Left Circumflex and Right Coronary Arteries in patients aged 45. The result was statistically significant (26.4% and 31.9% vs 46.4% and 57.2%, p=0.002 and 0.001). Conclusion: the number of coronary artery diseases (vessel score) and stenosis score is lower in patients aged 45 years compared to patients aged >45 years.
    Acta medica Indonesiana 04/2014; 46(2):117-23.
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    ABSTRACT: Aim: to investigate the effect of low birth weight (LBW) on endothelial function, and to determine the role of plasma adiponectin in endothelial dysfunction by conducting flow mediated brachial artery (FMBA) test or vasodilation response (VR) and by measuring plasma asymmetrical dimethylarginine (ADMA) of young adults born with LBW. Methods: in a retrospective cohort study, subjects were randomly selected from the growth study cohort of Tanjungsari Sumedang district West Java. They consisted of 67 LBW and 67 NBW (Normal Birth Weight) young adults. Dependent variables were plasma adiponectin, plasma ADMA, and VR. The correlation between plasma adiponectin and ADMA level was examined using Pearson's correlation. Results: the relative risk for LBW to have low brachialis artery vasodilation response was 2.94, (95% CI:1.91-4.53), and to have low of plasma adiponectin concentration 1.53, (95% CI: 1.07-2.18). There was a statistically significant difference for all variables studied (FMBA, plasma ADMA, and plasma Adiponectin concentrations), while simultaneous confidence interval measurements indicated that the value of FMBA and the concentration of plasma adiponectin were significantly lower, respectively p<0.001, 95% CI: -4.409-(-2.114), and p=0.015, 95% CI: -1.083-(-0.082) in LBW compared to NBW subjects. The correlation between plasma adiponectin concentration and plasma ADMA concentration in LBW subjects was not significant. Conclusion: there is an effect of LBW on endothelial function. LBW compared to NBW subjects have lower VR and plasma adiponectin concentration. There may be a small role of plasma adiponectin in endothelial dysfunction of young adults with LBW.
    Acta medica Indonesiana 04/2014; 46(2):111-6.
  • Acta medica Indonesiana 04/2014; 46(2):81-2.
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    ABSTRACT: Sickle cell anemia is an inherited abnormality of the globin chain with very high prevalence in the Indian subcontinent. A significant proportion of these patients present late in life and are at a risk of complications like acute chest syndrome and painful episodes till a definitive diagnosis is reached and appropriate treatment is started . We report a novel triad of abdominal imaging findings which is not reported in literature until now and which may suggest a diagnosis of sickle cell anemia in retrospect. Patients with this triad of abdominal findings should be suspected to have an underlying hemoglobinopathy and should be referred for further hematological workup. Although in our case the patient was diagnosed to have sickle cell anemia depending on the abnormal morphology of red cells and hemoglobin electrophoresis, it should be remembered that this triad of findings may be seen in other hemoglobinopathies which induce a state of chronic anemia.
    Acta medica Indonesiana 04/2014; 46(2):134-7.
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    ABSTRACT: A 67-year-old gentleman underwent fistulectomy for low trans-sphincteric anal fistula along with curettage for an associated abscess extending proximally for half a centimeter into the intersphincteric plane. The roof of the cavity became clearly visible after satisfactory culmination of the surgical procedure. Histopathological examination of the fistulous tract and the curetted granulation tissue revealed presence of multiple trophozoites of Entamoeba histolytica exhibiting erythrophagocytosis in the background of mixed inflammatory infiltrate. This case report provides the outlook that yields the novel insight into the possible role of Entamoeba histolytica in the pathogenesis and persistence of the fistulous tract.
    Acta medica Indonesiana 04/2014; 46(2):131-3.