Cardiovascular diseases (Cardiovasc Dis)

Publications in this journal

• Article: Humoral immune response to a 12 kDa antigen in patients with carotid atherosclerosis.

  Delunardo F, Margutti P, Riganò R, Profumo E, Siracusano A, Capoano R, Costanzo A, Carra A, Salvati B. and Ortona E
  Cardiovascular diseases 01/2002; 1(5):113.
• Article: Immunological markers of disease progression in patients with carotid atherosclerosis

  Profumo E, Siracusano A, Ortona E, Margutti P, Capoano R, Costanzo A, De Pasquale F, Salvati B. and Riganò R
  Cardiovascular diseases 01/2002; 1(5):107.
• Article: The reality of a self-occluding pump head: Case report.

  Susie Seiferd, Diane K. Clark, Charles C. Reed
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  ABSTRACT: A malfunction of an oxygenator pumphead during aortocoronary bypass surgery is described. Corrections were made and the operation proceeded without further incident. Although this malfunction is extremely rare, it is reviewed in detail to alert perfusionists to the possibility of such an occurrence.
  Cardiovascular diseases 01/1982; 8(4):567-568.
• Source

  Available from: nih.gov

  Article: Chronic traumatic popliteal arteriovenous fistula: Case report.

  A Thomas Pezella, Richard Yeager
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  ABSTRACT: Chronic popliteal arteriovenous fistula is a common result of penetrating vascular trauma. Such a case, involving a young, active-duty soldier who received a gunshot wound to the back of his left leg, is reported. Operative findings confirmed the presence of a fistula and a dilated, tortuous popliteal vein. A 1-cm communication between the main popliteal vein and artery just above the knee was found. Division, with lateral venorrhaphy and end-to-end repair of the artery, was performed, with good results. Particularly stressed in this report is the importance of increased physician awareness, combined with an aggressive surgical approach to reduce the morbidity, especially the high amputation rate so often associated with this kind of penetrating vascular trauma.
  Cardiovascular diseases 01/1982; 8(4):531-536.
• Source

  Available from: nih.gov

  Article: Balloon catheter dilatation and thrombectomy for acute aortoiliac occlusion.

  Joseph P. Archie
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  ABSTRACT: A case of acute distal aortic thrombosis in an elderly high-risk patient was successfully managed with intraoperative thrombectomy and balloon catheter dilatation of the common iliac arteries. Balloon catheter dilatation may be indicated prior to bypass grafting in high-risk patients with acute aortoiliac thrombosis.
  Cardiovascular diseases 01/1982; 8(4):546-549.
• Source

  Available from: nih.gov

  Article: Transection of the aorta for repair of pulmonary artery branch stenosis after creation of a Waterston shunt.

  Arun K. Singh
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  ABSTRACT: Closure of a Waterston shunt can usually be performed at the time of corrective surgery, either from the inside of the aorta or by detaching it from outside the aorta and patching the pulmonary artery. We propose a different approach for closing the shunt and repairing pulmonary artery stenosis.
  Cardiovascular diseases 01/1982; 8(4):550-554.
• Source

  Available from: nih.gov

  Article: A clinical trial of the Bentley BOS-5 pediatric oxygenator.

  R Park Carmon, Cristine C. Clay, Trudi Stafford, Charles C. Reed
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  ABSTRACT: The performance of the Bentley BOS-5 pediatric oxygenator was evaluated on the basis of its response to maintain arterial pH between 7.35 and 7.45, arterial pO(2) between 100 and 200 mm Hg, and arterial pCO(2) between 35 and 45 mm Hg (Texas Heart Institute perfusion protocol). The oxygenator was found to be efficient at all flow rates employed; however, the pO(2) parameter could not be consistently maintained within protocol limits, but could be improved when a mixture of 5% carbon dioxide/95% oxygen was used for the duration of a case.
  Cardiovascular diseases 01/1982; 8(4):562-566.
• Source

  Available from: nih.gov

  Article: Use of interposed polytetrafluorethylene (PTFE) graft in distal splenorenal shunt.

  A Addison Barman, William Batiuchok, Saqib S. Chaudry, John J. Creedon
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  ABSTRACT: Two patients with massive upper gastrointestinal hemorrhages required transsplenic decompression of the esophageal varices, but because technical difficulties precluded tension-free anastomoses, interposition of PTFE grafts was used to solve these difficult situations.
  Cardiovascular diseases 01/1982; 8(4):555-557.
• Source

  Available from: nih.gov

  Article: Venous volume displacement plethysmography: Its diagnostic value in deep venous thrombosis as determined by receiver operator characteristic curves.

  Kevin J. McBride, Thomas F. O'Donnell, Stephen G. Pauker, Victor A. Millan, Allan D. Callow
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  ABSTRACT: The pitfall of several reviews of noninvasive venous assessment has been the expression of the test data solely in terms of diagnostic accuracy (the number of correct tests in ratio to all tests performed), where results of a test will vary according to disease prevalence. The advantages of receiver operator characteristic curve analysis are twofold: (1) it describes the dynamic relationship between sensitivity (the ratio of the number of true positive tests to the patients with deep venous thrombosis) and specificity (the ratio of true negative tests to the number of patients with no deep venous thrombosis) independent of disease prevalence; and (2) the threshold criteria that defines a positive test can be set by the best balance between sensitivity and specificity and then applied to a given patient population for its diagnostic accuracy. Venous volume plethysmography is a widely used, simple and rapid method. It was compared to the "gold standard" of phlebography in a prospective blind study of 70 limbs that were clinically suspect of having deep venous thrombosis (DVT). Venous volume displacement plethysmography was defined objectively by three quantitative parameters: (1) maximum venous outflow, (2) integer ratio, and (3) segmental venous capacitance ratio. The DVT (22 to 70 positive phlebograms) was divided by anatomic location into either calf vein DVT or proximal DVT (popliteal vein or above). By combining these three parameters, a balance between sensitivity and specificity was obtained to provide a rapid, objective method for screening patients with suspected DVT.
  Cardiovascular diseases 01/1982; 8(4):499-508.
• Source

  Available from: nih.gov

  Article: The ischemic lung: Role of the bronchial arteries in lung function.

  Rogelio A Ventemiglia, Berton Braverman, Jose Di Mauro, Rafael Castro, William Blair, Dimitrios Spigos, Jose Herscovich, Demetrio J. Vazquez, Arthur Haebich
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  ABSTRACT: A patient with a dissecting aortic aneurysm, Type 1, developed acute pulmonary edema unexplained by the usual etiologic factors. Pathologic evidence that bronchial arterial circulation was interrupted led us to hypothesize that pulmonary edema could be due to ischemia of the bronchial circulation. To test this hypothesis, two chronic studies were done in dogs. The first study consisted of selective ligation of the right posterior bronchial artery at its origin at the fifth or sixth intercostal artery. After recovery from surgery, biopsies were taken from the ipsilateral and contralateral lung at time periods from 5 hours to 11 days. Ischemic damage was found in seven of eight dogs (87.5%), and was confined to the right lung. Histological examination revealed initial congestion within 8 hours, followed by pulmonary edema within 72 hours, and finally, disruption of alveolar septa with small emphysematous bullae on the eleventh postoperative day. The left lung remained normal in histological appearance. The second study consisted of transplanting the bronchial artery to the pulmonary artery to create a low pressure system and low O(2) content, and to simulate a regional shock situation. In five of six dogs (83.3%), the anastomosis was occluded within 72 hours, probably due to pressure competition from small collateral bronchial circulation. However, in these five dogs, pulmonary vascular resistance increased by 53%, intrapulmonary shunting increased by 83%, and the alveolar-to-arterial oxygen gradient increased by 150 mm Hg. Pulmonary edema was again confined to the right lung. Bronchial arteriograms demonstrated the extensive and variable distribution of the bronchial circulation in dogs. In the sixth dog, the anastomosis remained patent with a left-to-right shunt, due to a larger bronchial arterial collateral circulation. In this animal, the pulmonary arterial resistance, intrapulmonary shunting, and alveolar-arterial O(2) gradient were normal. Pulmonary edema was absent in lung biopsies. Bronchial circulation is discussed with respect to its clinical implications for lung transplants, shock, thoracic aneurysms, and mediastinal surgery. The results of this study suggest that the systemic bronchial circulation is important for normal lung function.
  Cardiovascular diseases 01/1982; 8(4):480-498.
• Article: Dextrocardia with situs inversus totalis: Cardiovascular surgery in three patients with concomitant coronary artery disease.

  Douglas P. Grey, Denton A. Cooley
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  ABSTRACT: Three patients with situs inversus totalis (mirror-image dextrocardia) and concomitant coronary artery disease were admitted to our institution for evaluation. In all cases, aortocoronary bypass grafting was successful. Patients with situs inversus and mirror-image dextrocardia are believed to have normal longevity, and, as these studies suggest, they have the same long-term prognosis after coronary bypass grafting as patients with situs solitus.
  Cardiovascular diseases 01/1982; 8(4):527-530.
• Source

  Available from: nih.gov

  Article: Evaluation of a new modified pediatric bubble oxygenator.

  Charles C. Reed, Kenneth P. Malloy, Diane K. Clark
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  ABSTRACT: A comparison was made of the S-070 Pediatric Bubble Oxygenator, which was unreliable above flow rates of approximately 1.5 L/min, with a modified S-070A, which proved to be extremely efficient to flow rates of 2.5 L/min.
  Cardiovascular diseases 01/1982; 8(4):569-574.
• Source

  Available from: nih.gov

  Article: A normal coronary arteriogram in a very young man with Prinzmetal's variant angina: Case report with review of the literature.

  Alfredo Balvanera, Julio Frade, Alberto Zamora, Jose Luis Robledo
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  ABSTRACT: The case of a very young man with Prinzmetal's variant angina and a normal coronary arteriogram is described. While in the hospital for diagnosis, he experienced severe chest pain accompanied by transient ST segment elevation. After intravenous administration of Ergonovine Maleate (0.4 mg), spastic obstruction of the right coronary artery was observed. He was treated successfully with nifedipine, and during 4 months of follow-up, he has had no symptoms. Because of the diagnostic interest in this type of angina in a young person, the literature on Prinzmetal's angina has also been reviewed.
  Cardiovascular diseases 01/1982; 8(4):537-545.
• Source

  Available from: nih.gov

  Article: Blood velocity measurement in human conjunctival vessels.

  Harvey N. Mayrovitz, Donald Larnard, Gloria Duda
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  ABSTRACT: The bulbar conjunctiva is one of the few areas in which blood flow in the peripheral vasculature can be directly and noninvasively observed in the human. Although extensive literature exists describing morphological changes which correlate with a variety of systemic diseases in this vasculature, little quantitative data is available on hemodynamics in either normal or abnormal states. The hemodynamic data available are primarily subjective assessments of "low flow." Approaches to place the subjective assessment on more quantitative grounds have usually been based on photographic techniques that have intrinsic inadequacies. The objective of the work reported here was to develop a system capable of providing sequential blood velocity data potentially useful for providing quantitative information on blood flow and its change in the microvessels of the human conjunctiva. The method that has evolved uses a standard Zeiss slit-lamp to image a subject's conjunctival vessels by using a 1-inch Newvicon TV camera with an electronic magnification of 2x. The video image is simultaneously recorded on a video tape recorder (VTR) to an overall system magnification of approximately 4 microm/raster line. The data acquisition phase requires approximately 5 minutes of patient time, whereas the actual determination of blood velocity in individual vessels is done offline through a modification of the dual-slit videodensimetric method. Two independently controllable video cursors are placed axially over the vessel image with the VTR in the still-frame mode. For each consecutive video field, the position of two reference points on the vessel and the position of each cursor relative to these and to each other are encoded into a computer to track the moving image caused by normal eye movement. The computer then determines new cursor coordinates to ensure a constant position within the vessel. The electrical signals obtained for each cursor site and for each video field are cross-correlated to yield the average blood velocity over the sampled time interval. The system has been calibrated in vitro from 0.2 to 2.5 mm/sec, evaluated in experimental animals, and used to measure blood velocity (0.3 to 1.5 mm/sec) in human conjunctival venules with diameters ranging from 20 to 50 microm. At this writing, blood velocity has been recorded during a period of about 3 months in the same vessel of several postmyocardial infarction patients. Thus, the method appears suitable for determining sequential changes in small vessel blood flow in patients over extended periods of time.
  Cardiovascular diseases 01/1982; 8(4):509-526.
• Source

  Available from: nih.gov

  Article: Coronary dilators and cardioplegia.

  Alexander Romagnoli, Adolph J. Koska
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  ABSTRACT: The distribution in the myocardium of cardioplegic solution is demonstrated in dog hearts with the aid of indocyanine green. When papaverine or nitroglycerin are added to the solution, a much improved diffusion is observed. Papaverine appears to be a better coronary dilator. We deduce from this observation that myocardial protection during ischemic arrest for open-heart surgery is enhanced considerably when coronary dilation is assured.
  Cardiovascular diseases 01/1982; 8(4):467-474.
• Article: Thoracic aortic thrombi and hypercoagulability.

  Michael A. Graham, Donald B. Butler, John D. Milam
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  ABSTRACT: This unusual report shows the association between thoracic aortic mural thrombus formation and the hypercoagulable state without concomitant disseminated intravascular coagulation. The patient's hypercoagulability was reflected by laboratory results that included elevated Factor VIII and fibrinogen levels, along with a decreased level of antithrombin III. The underlying cause was probably acute peritonitis, a condition associated with coagulopathy.
  Cardiovascular diseases 01/1982; 8(4):475-479.
• Source

  Available from: nih.gov

  Article: Clinical experience in 1040 patients with double-velour knitted Dacron vascular prostheses: With particular reference to dilatation and aneurysm formation.

  Denton A. Cooley, Aswath Subram, Dena P. Houchin
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  ABSTRACT: Recent reports of dilatation and aneurysm formation in Dacron fabric grafts have prompted us to review our experience with 1040 patients who received Meadox-Cooley double-velour knitted grafts over a 47-month period. Bifurcation grafts were used in 398 patients with aorto-femoral occlusive disease and in 203 patients with aortoiliac occlusive disease. Straight tube grafts were implanted in 310 patients with abdominal aortic aneurysms. Small caliber straight tube grafts were used for femoral-femoral bypass in 112 patients. The remaining 17 patients received double-velour grafts for restoration of the renal (14) and superior mesenteric (3) artery circulation. In a review of patients, no dilatation or aneurysm formation was disclosed by clinical examination, sonography or aortography.
  Cardiovascular diseases 10/1981; 8(3):320-332.
• Article: Congenital coronary artery-left heart fistulas: Report of three cases.

  A Thomas Pezzella, Giorgio Falaschi, David A. Ott, Denton A. Cooley
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  ABSTRACT: Of 59 patients who underwent operative correction of congenital coronary artery fistulas from May 1956 through May 1980 at our institution, three had fistulas that arose from the coronary artery and terminated in the left heart. The chief indication for surgical correction in such patients is the presence of symptoms or the development of complications, which include rupture, endocarditis, and congestive heart failure. The principal objective of repair is closure or obliteration of the fistulous communication and preservation of distal myocardial perfusion. Because symptoms and complications tend to occur with age, elective ligation is warranted during childhood, even in asymptomatic patients. The three cases described here, as well as the reviewed series of left heart fistulas, substantiate this fact. All three patients were symptomatic before operation and asymptomatic afterward.
  Cardiovascular diseases 10/1981; 8(3):355-363.
• Source

  Available from: nih.gov

  Article: Pharmacodynamics of fentanyl citrate in patients undergoing aortocoronary bypass.

  Adolph J Koska, Alexander Romagnoli, William G. Kramer
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  ABSTRACT: The pharmacodynamics of fentanyl citrate were studied in two groups of patients. One group underwent surgery with cardiopulmonary bypass (CPB) and the other group had surgery without CPB; the latter group represented the controls. Apneic periods were considerably longer (2.70 +/- 0.90 hr) for the CPB patients than for the control patients (1.75 +/- 0.75 hr). The total plasma fentanyl concentration at which apnea ceased was not statistically different between the two groups. Minor differences were attributed to the massive dilution of plasma proteins after the adding of priming fluid to the heart-lung machine. This prolongation of apnea is of considerable clinical importance because it means that CPB patients must remain mechanically ventilated for longer periods.
  Cardiovascular diseases 10/1981; 8(3):405-412.