Progress in experimental tumor research. Fortschritte der experimentellen Tumorforschung. Progrès de la recherche expérimentale des tumeurs (PROG EXP TUMOR RES )

Publisher: Karger

Description

Scientists who are eager to take part in novel approaches to cancer research rely upon this series as a major information source. The individual volumes provide exceptionally detailed coverage of topics selected as either representing controversial problems or belonging to areas where the speed of developments necessitates the kind of assistance offered by integrative, critical reviews. Expertly edited as well as authored, these books have attracted broad attention as records of both the sophistication and diversity of efforts to understand, prevent or control cancerous diseases

  • Impact factor
    0.42
    Show impact factor history
     
    Impact factor
  • 5-year impact
    0.98
  • Cited half-life
    0.00
  • Immediacy index
    0.00
  • Eigenfactor
    0.00
  • Article influence
    0.27
  • Website
    Progress in Experimental Tumor Research website
  • Other titles
    Progress in experimental tumor research, Experimental tumor research, Fortschritte der experimentellen Tumorforschung
  • ISSN
    0079-6263
  • OCLC
    1695607
  • Material type
    Series
  • Document type
    Journal / Magazine / Newspaper

Publisher details

Karger

  • Pre-print
    • Author can archive a pre-print version
  • Post-print
    • Author can archive a post-print version
  • Conditions
    • On author's server or institutional server
    • Server must be non-commercial
    • Publisher's version/PDF cannot be used
    • Publisher copyright and source must be acknowledged
    • Must link to publisher version
  • Classification
    ​ green

Publications in this journal

  • Progress in experimental tumor research. Fortschritte der experimentellen Tumorforschung. Progrès de la recherche expérimentale des tumeurs 02/2008; 40:111-21.
  • Progress in experimental tumor research. Fortschritte der experimentellen Tumorforschung. Progrès de la recherche expérimentale des tumeurs 02/2008; 40:25-31.
  • Progress in experimental tumor research. Fortschritte der experimentellen Tumorforschung. Progrès de la recherche expérimentale des tumeurs 02/2008; 40:51-5.
  • Progress in experimental tumor research. Fortschritte der experimentellen Tumorforschung. Progrès de la recherche expérimentale des tumeurs 02/2008; 40:122-34.
  • Progress in experimental tumor research. Fortschritte der experimentellen Tumorforschung. Progrès de la recherche expérimentale des tumeurs 02/2008; 40:138-44.
  • Progress in experimental tumor research. Fortschritte der experimentellen Tumorforschung. Progrès de la recherche expérimentale des tumeurs 02/2008; 40:102-10.
  • Progress in experimental tumor research. Fortschritte der experimentellen Tumorforschung. Progrès de la recherche expérimentale des tumeurs 02/2008; 40:85-91.
  • Progress in experimental tumor research. Fortschritte der experimentellen Tumorforschung. Progrès de la recherche expérimentale des tumeurs 02/2008; 40:17-24.
  • Progress in experimental tumor research. Fortschritte der experimentellen Tumorforschung. Progrès de la recherche expérimentale des tumeurs 02/2008; 40:62-84.
  • Progress in experimental tumor research. Fortschritte der experimentellen Tumorforschung. Progrès de la recherche expérimentale des tumeurs 02/2008; 40:7-16.
  • Article: Lymphomas.
    Progress in experimental tumor research. Fortschritte der experimentellen Tumorforschung. Progrès de la recherche expérimentale des tumeurs 02/2008; 40:32-44.
  • Progress in experimental tumor research. Fortschritte der experimentellen Tumorforschung. Progrès de la recherche expérimentale des tumeurs 02/2008; 40:56-61.
  • Progress in experimental tumor research. Fortschritte der experimentellen Tumorforschung. Progrès de la recherche expérimentale des tumeurs 02/2008; 40:1-6.
  • Article: Leukemias.
    Progress in experimental tumor research. Fortschritte der experimentellen Tumorforschung. Progrès de la recherche expérimentale des tumeurs 02/2008; 40:45-50.
  • Progress in experimental tumor research. Fortschritte der experimentellen Tumorforschung. Progrès de la recherche expérimentale des tumeurs 02/2008; 40:92-101.
  • Progress in experimental tumor research. Fortschritte der experimentellen Tumorforschung. Progrès de la recherche expérimentale des tumeurs 02/2008; 40:135-7.
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    ABSTRACT: Skin, musculoskeletal system and all organs of the body are supplied by nerve fibers of the somatic and autonomic nervous system, each of the systems with its specific nerve fiber types, fiber composition, fiber density and targets. Experimental data support the hypothesis that tumor tissue might interact with nerve fibers. The peripheral nervous system possesses an extraordinary cellular equipment to protect the axons against pathological stimuli. Only restricted areas lacking a cellular barrier are weak points within the nervous network. Therefore, this article focuses on the functional morphology of the peripheral nervous system and its regional differences.
    Progress in experimental tumor research. Fortschritte der experimentellen Tumorforschung. Progrès de la recherche expérimentale des tumeurs 02/2007; 39:30-44.
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    ABSTRACT: Many proteins first identified in the nervous system were also found to be expressed elsewhere in the body. The text reviews some of these 'neuronal' markers and delineates intersections between nervous and non-nervous tissues on the structural and functional level. Examples are given for nuclear antigens, cytosolic, cytoskeletal and membrane bound proteins, neurotrophic factors and developmental antigens. Clinical aspects of the expression of neuronal antigens in cancer-like paraneoplastic syndromes of the nervous system and tumor invasion along and within peripheral nerves are discussed. The accumulated data indicates that expression of "neuronal" protein in tumors may promote proliferation, invasiveness and metastatic spread. The large spectrum of neuronal antigens expressed in cancer including voltage-gated ion channels and numerous neurotrophic factors reflects the continuity from neuronal to non-neuronal differentiation.
    Progress in experimental tumor research. Fortschritte der experimentellen Tumorforschung. Progrès de la recherche expérimentale des tumeurs 02/2007; 39:64-77.
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    ABSTRACT: Biological tools that are unleashed in malignancies are employed in a controlled manner during neuronal development. By default, early embryonic cells would become neuronal stem cells, a path that is blocked by specific signaling pathways. The future nervous system only develops where this blockade is inhibited by inductive signals from the 'organizer'. Once the future brain and spinal cord regions are determined, the mitotic potential in this region must be maintained long enough to produce all cells required, but also be controlled to avoid excessive over-production of cells. Newly generated cells must then migrate to their future destination, they must know where to settle down, and they must differentiate. To shape the developing nervous system and to adapt its functionality to the postnatal environment, cell survival must be regulated, i.e. survival of some cells is supported while death of others is induced. Thus, inductive events, proliferation, cell migration, differentiation, cell survival and cell death are highly regulated during neuronal development, while these functions are de-regulated in malignancies. The molecular pathways for neuronal development mutually modulate each other and are still present in the adult nervous system. Because many of these pathways are implicated in tumors, neurons may affect these conditions.
    Progress in experimental tumor research. Fortschritte der experimentellen Tumorforschung. Progrès de la recherche expérimentale des tumeurs 02/2007; 39:1-29.
  • [Show abstract] [Hide abstract]
    ABSTRACT: Other sections of this monograph, dedicated to neuronal activities in tumor tissue, have highlight the chief influence of neurotrophins, neurotransmitters, adhesion, guidance molecules and different nerve cell markers in the progression, but also for the prognostic, therapy and survey of cancers. The G-protein-coupled receptors (GPCR) are among the most successful and promising target proteins for drug discovery and therapeutic research. GPCR are frequently overexpressed in cancer cells, an interesting property for tumor imaging or for a targeted radiotherapy, using radiolabeled ligand derivatives. The tumor microenvironment contains a number of GPCR ligands (e.g., bioactive peptides, biogenic amines, purins, chemokines), known to regulate the proliferation, migration or survival of both tumoral and neural cells and that may be key actors of the neuro-neoplastic interactions. Here will be reviewed the potential utilization of substances that target a selected choice of GPCR, especially neuropeptide receptors, for a novel concept of therapy, concerning the numerous types of cancers where neurons infiltrate the tumoral mass or those where the malignant cells invade nerve branches (perineural invasion). Some molecular mechanisms linked to these GPCR (or linking GPCR to other types of membrane receptors or co-receptors), involved in these processes, will also be considered.
    Progress in experimental tumor research. Fortschritte der experimentellen Tumorforschung. Progrès de la recherche expérimentale des tumeurs 02/2007; 39:130-53.