Vestnik otorinolaringologii Journal Impact Factor & Information

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Other titles Vestnik otorinolaringologiĭ
ISSN 0042-4668
OCLC 1777883
Material type Periodical
Document type Journal / Magazine / Newspaper

Publications in this journal

  • [Show abstract] [Hide abstract]
    ABSTRACT: We have developed the new method for the analysis and visualization of the fine temporal structure of the transient evoked otoacoustic emission signal. The method consists of the presentation of the signal in the form of a set of tone components with a rapidly changing amplitude and relatively stable frequency. It is based on the combination of three spectrograms differing in frequency and temporal resolution by means of fuzzy logic amplitude estimation with subsequent frequency refining with the use of the least square procedure, reduction of the number of the insignificant components, and final re-ordering of the results for the simplification of further data processing. The new method was named Pitch Envelope Analysis (PEA). For data representation, a new type of diagram named componentogram was designed. The proposed method can be used for the real time processing of the continuous data stream especially for speech processing.
    Vestnik otorinolaringologii 01/2014;
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    ABSTRACT: The objective of the present study was to estimate the effectiveness of the herbal preparation tonsilgon N exhibiting the anti-inflammatory and immunostimulating properties for the treatment of the children presenting with pathology of a pharyngeal tonsil. A total of 62 children at the age varying from 3 to 11 years with chronic adenoiditis (CA) were available for the examination. The study group was comprised of 32 children, the control one included 30 patients. The study has demonstrated the improvement of daytime nasal breathing in the study group compared with the control patients by 15% on day 5, by 30% on day 7, and by 73% on day 9 after the onset of the treatment. The intensity of rhinorrhea in the children treated with the herbal preparation decreased sooner than in the control group. Nasal breathing at night improved as soon as day 5 after the onset of therapy. However, the difference between the treated and control children was statistically significant only on day 7 whereas night-time nasal breathing on day 9 improved in the study group by 1.4 times compared with the control one. It is concluded that the inclusion of therapy with tonsilgon N in the combined treatment of the children presenting with chronic adenoiditis increases its effectiveness and accelerates the process of reconvalescence. Tonsilgon N is a safe medication suitable for the prolonged application.
    Vestnik otorinolaringologii 01/2014;
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    ABSTRACT: The objective of the present was to evaluate the influence of local anesthetics protargol, miramistin, chlorohexidine, and photodynamic therapy (PDT) on the polyresistant strain of Candida tropicalis isolated from a sick child presenting with fungal adenoiditis. In vitro experiments were designed to estimate the inactivation potential of the Candida tropicalis blastospore suspension (5·107 CFU/ml) following the preliminary incubation with a 5 mcmol/l methylene blue solution. A Kreolka FDT apparatus operated at the 680 nm wavelength was employed as the source of radiation in a broad power and time ranges. Simultaneously, experiments were carried out to determine the minimum concentration of the protargol, miramistin, and chlorohexidine solutions inhibiting the growth of the same fungal strain. The minimum growth inhibitory concentrations of these solutions were found to be 0.1%, 0.005%, and 0.005% respectively. The photodynamic therapy using the minimal inhibitory dose of 150 J with a 5 min exposition and an output power of 0.5 W completely suppressed the growth of the Candida tropicalis colonies in the presence of methylene blue as the photosensitizer.
    Vestnik otorinolaringologii 01/2014;
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    ABSTRACT: The Russian Federation similar to many other countries witnesses the continuous rise in the number of patients undergoing bilateral cochlear implantation. The objective of the present study was to estimate the effectiveness of rehabilitation following bilateral cochlear implantation. A total of 28 patients admitted to the Russian Research and Practical Centre of Audiology and Hearing Rehabilitation between 2011 and 2012 were available for the examination with the use of tonal threshold audiometry. Twenty one patient underwent sequential cochlear implantation, simultaneous implantation was effected in the remaining 7 ones. The patients were tested by a speech therapist. The tonal threshold audiometry in the free sound field showed that the auditory thresholds corresponded to grade I hearing impairment. Free-field sound perception threshold in the bilaterally implanted patients with two active speech processors was significantly better than in those having one speech processor. All the patients exhibited binaural summation effect. Surdopedagogical testing revealed positive dynamics of the speech development. The positive dynamics was especially well apparent pronounced in the patients operated simultaneously or when the period between two implantations did not exceed 1 year. A reduction of the duration of the period between two surgical interventions resulted in the decreased difference between sound perception in two ears, improvement of sound localization, and acceleration of speech development. All the patients showed good speech recognition in the complex acoustic environment and the ability to locate sounds.
    Vestnik otorinolaringologii 01/2014;
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    ABSTRACT: This paper reports an observation illustrating the possibility of the successful surgical treatment of otosclerosis in a HIV-infected patient presenting with acquired immunodeficiency syndrome (AIDS) and positive response in the test for hepatitis C. The authors used the results of multispiral computed tomography (MSCT) of the temporal bones as a basis for the prediction of the outcome of the surgical intervention taking into consideration specific primary manifestations of HIV infection as well as immunological and virlogical responses to anti-retroviral therapy.
    Vestnik otorinolaringologii 01/2014;
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    ABSTRACT: The objective of the present work was to evaluate the morphofunctional state of the polypous tissue under conditions of radiofrequency-wave (from 15 to 40 W) and laser interstitial (from 1 to 10 W) thermal therapy. It was shown that both techniques exerted no influence on the structure and physiology of epithelial glands, regardless of the regime chosen for their application. The therapeutic effect was achieved due to the influence of radiation on the loose connective tissue leading to the modification of its structure and the reduction of the volume of the polypous tissue. Laser interstitial thermal therapy at 3-7 W was found to be the most efficacious and injurious regime. In contrast, laser radiation over 7 W and radiofrequency-wave treatment (15-40 W) proved the most traumatic regimes. They cause coagulation and tissue necrosis at the sites of their direct application; these effects were strongly dependent on the radiation power.
    Vestnik otorinolaringologii 01/2014;
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    ABSTRACT: The objective of the present study was to evaluate the effectiveness ascoril therapy in comparison with the treatment using the mucoactive agent lazolvanom in the adult patients suffering from productive cough associated with acute viral respiratory infection. Patients and methods. The study included 120 patients suffering from productive cough associated with acute viral respiratory infection. They were divided into two groups. The patients comprising group 1 (n=6.) were treated with ascoril, those in group 2 (n=60) were given lasolvan. Results. The effectiveness of the treatment of cough in group 1 was found to be higher compared with that in group 2 (p<0.05); moreover, it was associated with better dynamics of certain indicators of the quality of life, such as the social activity level, vitality, and general health (p<0.05). The safety of the proposed treatment was confirmed by the absence of the adverse events throughout the entire treatment period.
    Vestnik otorinolaringologii 01/2014;
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    ABSTRACT: The objective of the present work was to study various stages of morphogenesis of the stromal tissue of nasal polyps. The materials for the investigation were harvested during endoscopic polypotomies in the nose. They were used to obtain the preparations that were stained by the histological and histochemical methods. The immunochemical studies were carried out using monoclonal antibodies against differentiation clusters, such as CD20, CD31, and vascular endothelial growth factor (VEGF). The study has demonstrated that the growth and evolution of the nasal polyps are accompanied by sequential alterations in the morphological structure of their stromal tissue. The results of the investigations were used to develop the original classification of the selected stages of morphogenesis of the stromal tissue of nasal polyps. The following stages were distinguished: edematous one, inflammatory cellular infiltration, fibrous cirrhotic alterations, and vasculogenesis or neoangiogenesis.
    Vestnik otorinolaringologii 01/2014;
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    ABSTRACT: The objective of the present work was the comparative analysis of the results of the application of different methods for the treatment of the children presenting with vasomotor rhinitis. It was shown that the proposed combined approach including remedial therapy for the normalization of the function of the vegetative nervous system and the local application of fluctuating current to the nasal cavity mucosa has an advantage over the traditional modalities. Specifically, this newly developed simple and efficacious method for the combined conservative treatment of vasomotor rhinitis in the children has practically no contraindications for use, yields the most stable positive functional outcomes, and can by recommended for the application in both inpatient and outpatient settings to manage the patients with vasomotor rhinitis.
    Vestnik otorinolaringologii 01/2014;
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    ABSTRACT: The objective of the present study was the characteristic of the sense of smell and comparison of its peculiarities in the patients presenting with Parkinson's disease and polypous sinusitis based on the results of otorhinolaryngological examination with the use of the Sniffin' Sticks test. A total of 31 patients with polypous rhinosinusitis (PRS) (18 men and 17 women at the age of 44-58 years ) and 97 patients with Parkinson's disease (PD) (47 men and 50 women at the age of 50-56 years) were enrolled in the study. It was shown that 85% of the patients with PRS and PD suffered from olfactory disorders. The evaluation of selected parameters determined by the Sniffin' Sticks test demonstrated the impairment of the sense of smell in 48% of the patients with PRS and in 54% of those having PD. The main difference between the two groups was in the odour threshold that was reduced in 97% of the patients with PRS and in 72% of the cases with PD and in the ability to distinguish between odours that was compromised in 37% and 78% of these patients respectively.
    Vestnik otorinolaringologii 01/2014;
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    ABSTRACT: The objective of the present study was to elucidate the structural and functional mechanisms underlying disturbances of the protective nasolaryngeal barrier with special reference to the following histological and immunohistochemical characteristics of the pharyngeal tonsils (CD4, CD20, CD68, IgA, P53, BCL2, Ki67, TGF-beta) in the children aged 3-6 years and presenting with complicated (n=20) or uncomplicated (n=20) chronic adenoiditis (CA). It was shown that adenoids of the patients with complicated chronic adenoiditis less frequently exhibit markers of active inflammation, such as hyperemia, intraepithelial infiltration, and hemosiderophages. Also, they have the smaller mean area of lymphoid follicles and the number of functional intrafollicular macrophages suggesting impaired immunological reactivity. Lymphoid follicles of the pharyngeal tonsils in the children with uncomplicated chronic adenoiditis show up enhanced density of B-lymphocytes (CD20) and CD69-positive cells which may suggest functional tension. However, density of IgA-producing lymphocytes responsible for the protection of nasolaryngeal mucosa is identical in the patients with complicated and uncomplicated chronic adenoiditis. Taken together with the decreased number of T-helpers (CG4), this finding indicates the compromised immunological response in the children with this pathology. It is concluded that the structural characteristics of pharyngeal tonsils revealed in the present study may provide a basis for the disturbances of congenital and adaptive immunity; moreover, they can serve as the predictors of complications of chronic adenoiditis.
    Vestnik otorinolaringologii 01/2014;
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    ABSTRACT: The objective of the present study was to determine the amount of products of lipid peroxidation (dienic conjugates and malonic dialdehydes) together with antioxidative enzymes (catalase and superoxide dismutase) in 47 children presenting with acute pyo-inflammatory otitis media (APIOM) and 125 patients with chronic suppurative mesotympanitis (CSMT). In addition, 49 children presenting with chronic suppurative epitympanitis (CSET) and chronic suppurative epimesotympanitis (CSEMT) were included in the study. The data obtained were analysed and compared with the similar characteristics of 28 healthy children of the same age comprising the control group. The age of the children in different groups varied between 2 and 14 years. The study revealed the increase in the amount of lipid peroxidation products in all the groups with the simultaneous reduction of the activity of antioxidative enzymes; moreover, these values changed depending on the form and clinical course of the disease.
    Vestnik otorinolaringologii 01/2014;
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    ABSTRACT: The objective of the present work was to detect and elucidate effects of a single factor (gas pressure) responsible for the threshold levels of stapedius reflex. It was shown that the threshold reflexes were recorded at 105 dB SPL when the gas pressure in the external auditory meatus decreased by 150-200 pPa against the atmospheric pressure and when it increased by 100-150 pPa. These effects can be accounted for by the reduced compliance of the tympanic membrane and different changes in the state of the auditory ossicles undergoing compression and tension. When entering the most comfortable stapedial reflex levels into the patient's tuning chart, an account should be taken of the maximum value of tympanic membrane compliance.
    Vestnik otorinolaringologii 01/2014;
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    ABSTRACT: The objective of the present work was to study the contribution of biofilms to the development of chronic bacterial rhinosinusitis. A total of 50 patients with this pathology were available for the examination. Mucosal swabs were taken from the middle nasal passages of all the patients to be used for the detection of biofilms by luminescence microscopy. The lactoferrine content in mucosal secretion from the nasal cavity was determined by an immunoenzymatic assay. Two groups of the patients presenting with bacterial rhinosinusitis were distinguished in the study of impression smears from nasal cavity mucosa by luminescence microscopy; one of them was comprised of biofilm-positive patients the other of biofilm-negative ones (56% and 44% respectively). The patients showing biofilms over nasal cavity mucosa had the lactoferrine content in mucosal secretion on the order of 0.0033±0.0008 mg/l compared with 0.0068±0.00075 mg/l in the biofilm-negative patients and 0.55±0.0005 mg/l in the healthy volunteers (controls). In other words, the biofilm-positive patients presenting with chronic bacterial rhinosinusitis had two times lower content of lactoferrine in mucosal secretion from the middle nasal passages than those in the biofilm negative group and 126 times lower content of lactoferrine than in the control group.
    Vestnik otorinolaringologii 01/2014;
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    ABSTRACT: The objective of the present paper was to propose an optimal scope of diagnostic studies for the patients complaining of rhinitis symptoms for the early detection of allergic rhinitis, including a differential diagnosis with associated respiratory tract infections. A comprehensive treatment is offered including the use of vasoconstrictors and antihistamines, eliminationand immunocorrectivetherapy with Ribomunyl.
    Vestnik otorinolaringologii 01/2014;
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    ABSTRACT: This paper reports a clinical case that gives evidence of the possibility of cochlear implantation after liver transplantation. Patient K. aged 3 years 10 months was admitted to the Russian Research and Practical Centre of Audiology and Hearing Rehabilitation with the diagnosis of type IB glycogenosis after maternal liver transplantation associated with chronic neutropenia, chronic cutaneous and mucosal infection, partial symptomatic partial epilepsy, retarded psycho-motor development, and complaints of the absence of auditory response. The audiological examination provided materials for the diagnosis of grade IV bilateral sensorineural hearing loss tending toward deafness. Cochlear implantation recommended to the patient was performed on February 20, 2013 using the HiRes 90 K implant with the HiFocus Helix electrode (Advanced Bionics, USA). The surgical intervention and the postoperative period passed without complications. The speech processor was activated one month after surgery. The results of surdopedagogical testing gave evidence of successful rehabilitation promising the further improvement. It is concluded that immunosuppressive therapy is not an absolute contraindication for cochlear implantation, but this procedure requires detailed examination and thorough preparation for the forthcoming surgery.
    Vestnik otorinolaringologii 01/2014;
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    ABSTRACT: Auditory neuropathies (auditory neuropathy spectrum disorders, ANSD) may be a consequence of dysfunction of inner hair cells and/or of synapses between these cells and auditory nerve fibers. Another cause of these disorders is supposed to be pathological changes in the auditory nerve itself. The outcome of the rehabilitative treatment of the patients presenting with this disorder depends on the quality of diagnosis and precise location of the pathological process. The present study involved 82 patients with auditory neuropathies. The audiological data obtained in the course of this work were compared with the results of other authors published during the recent years. The objective audiological examination included electrocochleography, registration of auditory brainstem response (ABR) and otoacoustic emission of short-latency and long-latency evoked auditory nerve action potentials. High-amplitude cochlear microphonic and transient evoked otoacoustic emission (TEOAE) potentials were recorded in 82 patients. In 17 (20.7%) patients, otoacoustic emission disappeared in the course of time even though the microphonic potential remained stable. It was shown that the results of electrical acoustic correction in the patients exhibiting long-latency evoked auditory action potentials and positive ABR to electrical stimulation (positive promontory test) were better than in the remaining cases. The outcome of cochlear implantation to a large extent depended on the localization of the pathological process. Specifically, the results of the treatment of the patients with high-amplitude summation potentials, prolonged latency, and positive auditory action potentials in response to electrical stimulation (typical of pre-synaptic localization of the pathological process) were better than in the patients with normal summation potentials, pathological auditory nerve action potentials, TEOAE, and negative ABR to electrical stimulation (indicative of post-synaptic localization of the pathological process). In the latter group of patients, the results of cochlear implantation were far from being satisfactory. It is concluded that additional information facilitating categorization of the pathological process can be obtained by the identification of the genetic mutations responsible for the development of auditory neuropathies.
    Vestnik otorinolaringologii 01/2014;
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    ABSTRACT: The objective of the present work was to improve the effectiveness of early diagnostics, prophylaxis, and correction of hearing impairment in the patients presenting with congenital primary hypothyroidism (CPH). The results of observation of 73 cases indicate that the late onset of substitution therapy of CPH with levothyroxine has no negative effect on the hearing function. The prevalence of hearing impairment was shown to depend on the etiological variant of CPH.
    Vestnik otorinolaringologii 01/2014;
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    ABSTRACT: The objective of the present work was the microbiological analysis of laryngeal and tracheal mucosal swabs as well as the study of the contents of the tracheostomy tubes taken from the patients presenting with laryngeal and tracheal stenosis of different etiology. Both the in- and outpatients with different duration of the cannula-bearing period were involved. Special attention was given to the influence of the tracheal stents and the frequency of their cleaning on the microbiocenoses of the larynx and trachea. The study has demonstrated that the patients bearing cannulas are in need of everyday toilet of the tracheostomy tube and tracheostoma; also needed is the choice of the tubes with due regard for a the anatomical features along with general and local antibacterial therapy for reducing pathogenicity of microflora in the tracheobronchial tree and decreasing the frequency of postoperative complications.
    Vestnik otorinolaringologii 01/2014;
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    ABSTRACT: The objective of the present paper was to review international and national standards for the criteria of assessment of the noise-induced occupational loss of hearing. The importance of healthy hearing for the occupational safety is emphasized which implies the necessity of the more rigorous criteria for hearing conservation in the workers engaged in the noisy technological environment compared with those for the general population. A rationale for the development of the standard program of hearing conservation in the workers engaged in the noisy technological environment is proposed including hygienic norms and rules or national state standards.
    Vestnik otorinolaringologii 01/2014;