Nature (NATURE)

Publisher: Nature Publishing Group

Journal description

Publishes papers from any area of science with great potential impact.

Current impact factor: 42.35

Impact Factor Rankings

2015 Impact Factor Available summer 2015
2013 / 2014 Impact Factor 42.351
2012 Impact Factor 38.597
2011 Impact Factor 36.28
2010 Impact Factor 36.101
2009 Impact Factor 34.48
2008 Impact Factor 31.434
2007 Impact Factor 28.751
2006 Impact Factor 26.681
2005 Impact Factor 29.273
2004 Impact Factor 32.182
2003 Impact Factor 30.979
2002 Impact Factor 30.432
2001 Impact Factor 27.955
2000 Impact Factor 25.814
1999 Impact Factor 29.491
1998 Impact Factor 28.833
1997 Impact Factor 27.368
1996 Impact Factor 28.417
1995 Impact Factor 27.074
1994 Impact Factor 25.466
1993 Impact Factor 22.326
1992 Impact Factor 22.139

Impact factor over time

Impact factor
Year

Additional details

5-year impact 38.16
Cited half-life 9.60
Immediacy index 9.24
Eigenfactor 1.58
Article influence 20.84
Website Nature website
Other titles Nature, International weekly journal of science
ISSN 0028-0836
OCLC 1586310
Material type Periodical, Internet resource
Document type Journal / Magazine / Newspaper, Internet Resource

Publisher details

Nature Publishing Group

  • Pre-print
    • Author can archive a pre-print version
  • Post-print
    • Author cannot archive a post-print version
  • Restrictions
    • 6 months embargo
  • Conditions
    • Authors retain copyright
    • Author's pre-print on arXiv or bioRXiv
    • Author's post-print on author's personal website, institutional repository, PubMed Central or funding body's archive
    • Published source must be acknowledged
    • Must link to publisher version with DOI
    • Publisher's version/PDF cannot be used
  • Classification
    ​ yellow

Publications in this journal

  • [Show abstract] [Hide abstract]
    ABSTRACT: Adult stem cells occur in niches that balance self-renewal with lineage selection and progression during tissue homeostasis. Following injury, culture or transplantation, stem cells outside their niche often display fate flexibility. Here we show that super-enhancers underlie the identity, lineage commitment and plasticity of adult stem cells in vivo. Using hair follicle as a model, we map the global chromatin domains of hair follicle stem cells and their committed progenitors in their native microenvironments. We show that super-enhancers and their dense clusters (‘epicentres’) of transcription factor binding sites undergo remodelling upon lineage progression. New fate is acquired by decommissioning old and establishing new super-enhancers and/or epicentres, an auto-regulatory process that abates one master regulator subset while enhancing another. We further show that when outside their niche, either in vitro or in wound-repair, hair follicle stem cells dynamically remodel super-enhancers in response to changes in their microenvironment. Intriguingly, some key super-enhancers shift epicentres, enabling their genes to remain active and maintain a transitional state in an ever-changing transcriptional landscape. Finally, we identify SOX9 as a crucial chromatin rheostat of hair follicle stem cell super-enhancers, and provide functional evidence that super-enhancers are dynamic, dense transcription-factor-binding platforms which are acutely sensitive to pioneer master regulators whose levels define not only spatial and temporal features of lineage-status but also stemness, plasticity in transitional states and differentiation.
    Nature 03/2015; DOI:10.1038/nature14289
  • Nature 03/2015; 519(7544):410-411. DOI:10.1038/519410a
  • Nature 02/2015; 518(7539):447-447. DOI:10.1038/nj7539-447a
  • Nature 02/2015; 518(7539):450-450. DOI:10.1038/518450a
  • Nature 02/2015; 518(7539):298-299. DOI:10.1038/518298a
  • Nature 02/2015; 518(7539):300-300. DOI:10.1038/518300a
  • [Show abstract] [Hide abstract]
    ABSTRACT: Grid cells are neurons with periodic spatial receptive fields (grids) that tile two-dimensional space in a hexagonal pattern. To provide useful information about location, grids must be stably anchored to an external reference frame. The mechanisms underlying this anchoring process have remained elusive. Here we show in differently sized familiar square enclosures that the axes of the grids are offset from the walls by an angle that minimizes symmetry with the borders of the environment. This rotational offset is invariably accompanied by an elliptic distortion of the grid pattern. Reversing the ellipticity analytically by a shearing transformation removes the angular offset. This, together with the near-absence of rotation in novel environments, suggests that the rotation emerges through non-coaxial strain as a function of experience. The systematic relationship between rotation and distortion of the grid pattern points to shear forces arising from anchoring to specific geometric reference points as key elements of the mechanism for alignment of grid patterns to the external world.
    Nature 02/2015; 2015(518):207–212. DOI:10.1038/nature14151