Medicina Clínica (MED CLIN-BARCELONA)

Publications in this journal

• Article: [Bronchial carcinoid tumor: study of 60 patients.]

  Claudia Madrid-Carbajal, Marta García-Clemente, Ana Pando-Sandoval, Hugo Cubillas Martín, Teresa González-Budiño, Pere Casan-Clarà
  [show abstract] [hide abstract]
  ABSTRACT: BACKGROUND AND OBJECTIVE: To describe the casuistry of bronchial carcinoid tumor in the last 20 years in our hospital and determine survival after surgical treatment. PATIENTS AND METHOD: We retrospectively reviewed the medical records from January 1992 to June 2012 of patients diagnosed with carcinoid tumor by the pulmonary service. RESULTS: Fifty-two patients (87%) had typical carcinoid and 8 (13%) atypical carcinoid. The mean age at diagnosis was 60 years (SD: 14.4). There was no relationship between consumption of tobacco and carcinoid tumor. Twenty-two per cent were asymptomatic radiographic finding (incidental finding) Three patients showed carcinoid syndrome and one patient had Cushing syndrome. There was a right dominance and the mean lesion size was between 2.1 and 5cm. Nine per cent had lymph node involvement, predominantly in atypical carcinoid. Overall survival at 3.5 and 10 years was 94%, 86% and 82%. Survival at 5 years was 90% for typical and 86% for atypical and survival at 10 years was 85% for typical and 57% for atypical carcinoids. CONCLUSION: Carcinoid tumors are malignant tumors by their ability to metastasize. In our study, both histological type and staging were predictors of survival.
  Medicina Clínica 05/2013;
• Article: [Reply.]

  José María Egea-Mellado, María Jesús Juan-Fita, Inmaculada González-Gallego, Asunción Fernández-Sánchez
  Medicina Clínica 05/2013;
• Article: [Risk of hypercalcemia and hipervitaminosis D induced by calcifediol. Review of cases reported to the Spanish Pharmacovigilance System.]

  Núria Garcia Dolad, Gloria Cereza García, Mariano Madurga Sanz, Dolores Montero Corominas
  Medicina Clínica 05/2013;
• Article: [Research in health sciences, co-responsibility and social impact.]

  Paula Adam, Gaietà Permanyer Miralda
  Medicina Clínica 05/2013;
• Article: [Mass spectrometry-extended neonatal screening in tandem: Is more better?]

  Javier González de Dios, Carlos Ochoa Sangrador, Manuel Molina Arias
  Medicina Clínica 05/2013;
• Article: [Othello syndrome secondary to zonisamide.]

  Eduardo Rubio-Nazabal, Purificación Alvarez-Pérez, Teresa Lema-Facal, Soledad López-Facal
  Medicina Clínica 05/2013;
• Article: [Cat bite-induced cellulitis. Bergeyella zoohelcum.]

  Jesús Martínez-López, Antonio Moreno-Flores, María José Zamora-López, Patricia Alvarez-García
  Medicina Clínica 05/2013;
• Article: [Oral secondary effects of radiotherapy and chemotherapy in cancer of the cervicofacial region.]

  Antonio Bascones-Martínez, Marta Muñoz-Corcuera, Rafael Gómez-Font
  Medicina Clínica 05/2013;
• Article: [Toxicity by "chocho agua"]

  Santiago Nogué, Jorge Arbulú, Cèsar Blanché
  Medicina Clínica 05/2013;
• Article: [Multiple sebaceous hyperplasia secondary to ciclosporin in a heart transplant patient.]

  Emiliano Grillo, Silvia Pérez-Gala, Sergio Vano-Galván, Pedro Jaén-Olasolo
  Medicina Clínica 05/2013;
• Article: [Secondary necrotizing fasciitis linked to treatment with panitumumab.]

  Natalia de Amuriza-Chicharro, Cristina Gastalver-Martín, Susana Cortijo-Cascajares, José Miguel Ferrari-Piquero
  Medicina Clínica 04/2013;
• Article: [Under the volcano.]

  Jordi Casabona
  Medicina Clínica 04/2013;
• Article: [Reply.]

  Cristina Barneto, José R Garmendia, Julio Ardura, Juan P Casaseca
  Medicina Clínica 04/2013;
• Article: [An integral and direct management model of medical profesional responsibility insurance in Catalonia.]

  Josep Arimany-Manso, Esperanza L Gómez-Durán, Miguel Bruguera, Jaume Aubía
  Medicina Clínica 04/2013;
• Article: [Seroprevalence of Chagas disease and its determinants in children and adolescents from Cochabamba, Bolivia.]

  Cristina Masuet-Aumatell, Josep M Ramon-Torrell, Aurora Casanova-Rituerto, María Del Rosario Dávalos-Gamboa
  Medicina Clínica 04/2013;
• Article: [Lethal enterovirus myocarditis associated with rituximab and chemotherapy for follicular lymphoma.]

  Juan José Alonso, Araceli Cánovas, Gurutze Rubio
  Medicina Clínica 04/2013;
• Article: [Prevalence of vitamin B12 deficiency in patients with iron-deficiency anemia referred for evaluation in Internal Medicine.]

  Aída Gil Díaz, Alicia Conde Martel, Belén Alonso Ortíz, María Eugenia Arkuch Saade
  Medicina Clínica 04/2013;
• Article: [Treatment of systemic lupus erythematosus: Myths, certainties and doubts.]

  Guillermo Ruiz-Irastorza, Alvaro Danza, Munther Khamashta
  [show abstract] [hide abstract]
  ABSTRACT: Systemic lupus erythematosus (SLE) is a complex disease with different clinical forms of presentation, including a wide range of severity and organic involvement. Such circumstance, along with the fact of the uncommon nature of the disease and the absence of clinically representative response criteria, make it difficult to design controlled clinical trials in SLE patients. As a result, observational studies have a special relevance, being a source of valuable information of SLE prognosis and outcome as well as of the efficacy and adverse effects of the different therapies. Herein we update some of the main treatments used in SLE. Steroids may have more risks than benefits if used at high doses. New mechanisms of action have been described, supporting the use of lower doses, possibly with the same efficacy and less adverse effects. Intravenous pulses of cyclophosphamide still have a role in the treatment of proliferative lupus nephritis and other serious SLE manifestations. Mycophenolate mofetil has shown its efficacy both as induction and maintenance therapy of selected cases of lupus nephritis. Biological therapies have emerged as new promising options. Although clinical trials have not confirmed a clear superiority of rituximab in SLE, observational studies have shown good response rates in severe SLE manifestations or refractory forms. Belimumab has recently been added to the therapeutic armamentarium of SLE; although its place in clinical practice is not well-defined, it may be recommended in active patients with no response or good tolerance to standard therapies. Hydroxichloroquine improves survival, decreases the risk of thrombosis and flares and is safe in pregnancy, and should be considered the baseline therapy in most SLE patients.
  Medicina Clínica 04/2013;
• Article: [Quorum sensing in bacteria and yeast.]

  Gabriel Alberto March Rosselló, José María Eiros Bouza
  [show abstract] [hide abstract]
  ABSTRACT: Bacterial sets are complex dynamic systems, which interact with each other and through the interaction, bacteria coexist, collaborate, compete and share information in a coordinated manner. A way of bacterial communication is quorum sensing. Through this mechanism the bacteria can recognize its concentration in a given environment and they can decide the time at which the expression of a particular set of genes should be started for developing a specific and simultaneous response. The result of these interconnections raises properties that cannot be explained from a single isolated bacterial cell.
  Medicina Clínica 04/2013;
• Article: [Bisphosphonate related osteonecrosis of the jaw.]

  Miguel Ángel Cuervo Pinna
  Medicina Clínica 04/2013;