Lijec̆nic̆ki vjesnik (Lijec Vjesn )

Publisher: National Library of Medicine (U.S.); National Science Foundation (U.S.); United States. Dept. of Health, Education, and Welfare; Zbor liječnika Hrvatske


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Publications in this journal

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    ABSTRACT: Based on the data provided by the Registry of the Department of Psychiatry, General Hospital Bjelovar, an epidemiological study of the hospital treated patients for the years 1980, 1985, 1990, 1995, 2000, 2005 and 2010 was made. In determining the diagnostic groups, the authors used the International Classification of Diseases ICD-10 and the World Health Organization's (WHO) recommendations, adjusting all diagnostic entities to that classification. The study sample consists of patients hospitalized at the Department of Psychiatry, General Hospital Bjelovar in the years mentioned above. Following parameters were analyzed: total number of hospitalizations, gender, age and hospitalization outcome--by diagnostic groups. What is noted is the decrease in the total number of psychiatric hospitalizations, the reduction of the proportion of men and women in the sample, and the decrease of mortality. In the observed period, the number of hospitalized patients diagnosed as alcoholics decreased, and the number of patients hospitalized with diagnosed as alcoholics decreased, and the number of patients hospitalized with diagnosed dementia, affective disorders, and critical conditions increased, while the number of the hospitalized schizophrenic patients has been oscillating. The main differences between the results of the initial and final year of the epidemiological study have been analyzed by the chi square test. The results of the epidemiological study shall help the evaluation, rational planning and further development in the protection of mental health of the inhabitants of the Bjelovar-Bilogora County.
    Lijec̆nic̆ki vjesnik 07/2014; Liječ Vjesn 2014;136:140–146.
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    ABSTRACT: Pregnancy in patients suffering from chronic renal disease is still a rare phenomenon due to a number of factors that impair fertility in such patients, in spite of a number of new treatment techniques that have been introduced recently, e.g. renal replacement therapy with biocompatible dialysis membranes, highflux dialyzers, erythropoietins, and new types of peritoneal dialysis and higher level of care for such patients. Yet, when pregnancy occurs, it is possible to provide a safe outcome for both the mother and fetus. However, optimal conditions for hemodialysis and peritoneal dialysis should be provided. The data on pregnancy in patients suffereing from chronic renal disease are rather scarce, and have been derived from registers of dialyzed patients from few countries. Unfortunately, no such data are known for the patients in Croatia. This review deals with the specific approach to hemodialysis and peritoneal dialysis in patients with pregnancy and end-stage renal disease. Particular attention is paid to specific problems associated with gestation, delivery and care for patients, with special reference to prenatal and neonatal care.
    Lijec̆nic̆ki vjesnik 03/2014; 124(3-4):82-8.
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    ABSTRACT: Objective: To estimate the prevalence of symptoms of asthma, allergic rhinitis/rhinoconjuctivitis and atopic eczema symptoms in the Međimurje County in Northwest Croatia. Subjects and methods: The study was undertaken between January and April 2005 among school children in 27 randomly selected elementary schools. Data were collected using standardized ISAAC written questionnaire Phase I. Results: A total of 3106 children participated in the study (7-9 yrs) with response rate 96,94%. 712 (22,9%) children had symptoms of allergic diseases at some time in their life. Estimated lifetime (ever) prevalence rates of symptoms were: wheezing 14,91% , allergic rhinitis symptoms 8,88% and atopic dermatitis symptoms 10,66%. Estimated 12-month prevalence rates were: wheezing 6,92%, allergic rhinitis symptoms 8,40%, allergic rhinoconjunctivitis 4,67%, and atopic dermatitis symptoms 5,76%. Conclusions: The results of this study show that Međimurje County is an area with moderate prevalence of atopic disease symptoms among the pediatric population.
    Lijec̆nic̆ki vjesnik 01/2014; 136(3-4):73-78.
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    ABSTRACT: To investigate the prevalence of anxiety and depression in the elderly inhabiting Koprivnica-Kri evci, Istria and Dubrovnik-Neretva Counties and their association with socio-demographic characteristics and healthcare utilisation. A cross-sectional cluster survey carried out in 2006, encompassing a total of 1,469 examinees aged 70+. The Hospital Anxiety and Depression (HAD) Scale was used to screen for self-reported symptoms of anxiety and depression, which were further associated with socio-demographic characteristics and healthcare utilisation. The elderly have shown a high prevalence of borderline and probable anxiety (43%) and depression (53%), and regional differences (p<0.001). The level of anxiety was higher in women than men (p<0.001); as for depression, no statistically significant gender-based differences were found. The prevalence of probable depression increases (p=0.034) and that of probable anxiety decreases (p=0.028) with age. Anxiety and depression are associated with increased use of specialist health care and more frequent hospitalizations. High prevalence of anxiety and depression in elderly is associated with sociodemographic characteristics and frequent use of health care.
    Lijec̆nic̆ki vjesnik 11/2013; 135(5-6):134-8.
  • Lijec̆nic̆ki vjesnik 07/2013; 135:150-155.
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    ABSTRACT: Hematopoietic stem cell transplantation (HSCT) has become an effective therapeutic option for the treatment of severe cases of autoimmune diseases (AD). Hematopoietic stem cells (HSC) can be collected from the patient (autologous), identical twin (syngenic) or HLA identical donor (allogenous). In allogenous transplantation autoagressive immunological effector cells are substituted with non-autoagressive cells of the donor. Possible graft versus host reaction (GVHD) makes this type of transplantation less attractive. On the other hand, autologous transplantation can induce the >resetting< of immunological clock without any fear of GVHD, but it requires previous conditioning. As an alternative option, transplantation ofmesenchymal stem cells (MSS) was developed. MSS has a strong immunosuppressive effect, while it doesn't require previous conditioning, nor does it induce GVHD. Due to the treatment related mortality, these therapeutic option should remain reserved for the most severe cases of AD. Nevertheless, they present a great opportunity for these patients, and even a chance for full recovery.
    Lijec̆nic̆ki vjesnik 07/2013; 135(5-6):150-5.
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    Lijec̆nic̆ki vjesnik 06/2013; VOL 2(SUPPL 3):155-157.
  • Lijec̆nic̆ki vjesnik 01/2012;
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    ABSTRACT: Endoscopic mucosal resection (EMR) is a therapeutic method for removal of sesile premalignant lesions and intramucosal carcinoma of the gastrointestinal tract. No reports on EMR data in Croatia have been published yet. MATHERIALS AND METHODS: All patients included in the study were managed at the University Hospital Centre Zagreb between December 2006 and December 2008. EMR was performed using strip technique with submucosal injection of epinephrine (dilution with saline 1:5000-10000). EMR of sessile polypoid colorectal lesions was performed in 95 patients. The most common localisation of the disease was rectum (52 pts - 54.7%). In most patient size of the lesion was between 16-25 mm (43 pts - 45%). En-bloc resection was performed in 75 patients and piecemeal resection in the rest. Bleeding occurred immediately during the EMR in 5 pts (5.3%). Patohistological diagnosis revealed tubulovillous adenoma in 67 pts (70%). Invasive carcinoma was observed in 6 pts (6.3%) and intramucosal carcinoma in 20 pts (21%). On follow up, 73 pts (77%) did not show and sign of disease recurrence. Surgery was needed in 6 pts (6.3%) due to the diagnosis of invasive carcinoma. EMR is safe and reliable method with low risk of serious complications and acceptable recurrence rate.
    Lijec̆nic̆ki vjesnik 01/2011; 133(9-10):322-6.
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    ABSTRACT: The first annual meeting of Croatian physicians, with characteristics of a congress, was held in 1899 at the 25th anniversary of the Croatian Medical Association. From 1954 to 1996, during almost 60 years of existence of the Croatian Medical Association, ten congresses of the Association were held. The congresses were during the development of modern medicine devoted to different medical questions, including some problems of national pathology, of the structure and restructuring of health care. The work and the content of congresses were published in the proceedings except for the 8th Congress in 1987 and the 10th in 1996. By reading main lectures, invited lectures and free papers the knowledge of that period can be gained. Many papers are even today actual, even today it could be learned from them. With more details, using published proceedings the 9th congress and the 10th congress are described on the basis preserved program, of a brief report in home journal and ample preserved correspondence. The national medical congres dedicated to technology advancement and to numerous problems of national pathology may be actual even today. They could help to solve many problems of health care, contribute to its improvement and convey consensus on its further development.
    Lijec̆nic̆ki vjesnik 01/2011; 133(11-12):411-21.
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    ABSTRACT: This paper presents the case of a patient suffering from atypical depression, with excessive daytime sleepiness, which was a suicidal equivalent. Patients who suffer from depression and sleep disorders can have an increased risk of suicidality, and to them should pay increased attention. Field of suicide as a means of resolving conflicts and unconscious mental escape from the reality of the obstacles, including sleep and daytime sleepiness, which may represent a form of "temporary suicide". The authors recommend that hypersomnia, daytime sleepiness in depressed patients and other sleep disorders should be treated as a potential risk factor for suicidal behavior.
    Lijec̆nic̆ki vjesnik 01/2011; 133(7-8):263-8.
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    ABSTRACT: Healthcare associated infections (HCAI) are huge problem all over the world, and 5-10% of all hospitalized patients will develop infection during hospitalization. From the times of I. P. Semelweiss we know that clean hands are the most important single factor that can decrease the number of HCAI. World Health Organization (WHO) has recognised this problem and developed Guidelines for hand hygiene in healthcare institutions. This also was the reason of developing Croatian national Guidelines. The main goal of the Guidelines was to decrease number of HCAI associated with the hands of healthcare workers. These Guidelines are meant for all healthcare workers and other hospital staff who come to the direct contact with patients. An interdisciplinary team of experts developed these Guidelines using WHO Guidelines, other existing guidelines and literature reviews for hand hygiene. Grades of evidence for specific recommendations were determined using CDC/HICPAC grading system. Categorization is based on existing data, theoretical basis, applicability and economic impact. After a broad discussion in different professional societies, Guidelines were accepted. Guidelines include recommendations for hand hygiene indications, hand hygiene technique, surgical hand preparation, choosing hand hygiene preparations, skin care, nails, glove use, patients and visitors hand hygiene, role of education, as well as role of healthcare institution and role of government. Furthermore, in the Guidelines the concept of "Five moments for hand hygiene" is explained in detail, and main literature data are presented.
    Lijec̆nic̆ki vjesnik 01/2011; 133(5-6):155-70.
  • Lijec̆nic̆ki vjesnik 01/2011; 133(1-2):1-14.
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    ABSTRACT: It has been known for quite a long time that the concentration of HDL-cholesterol correlates inversely with cardiovascular disease (CVD) risk and that low HDL-cholesterol is an independent CVD risk factor. This review aims to highlight evidence on several topics concerning the role of HDL particles and the importance of HDL-cholesterol. The main antiatherogenic functions of HDL particles are presented in details--reverse cholesterol transport, but also their anti-oxidant, anti-inflammatory, anti-thrombotic and anti-apoptotic properties as well as endothelial stabilizing and repair properties. Lifestyle management of low HDL-cholesterol is explained, particularly physical activity and aerobic exercise, smoking cessation, weight reduction in the overweight individuals and composition of the diet but also moderate alcohol consumption stressing the fact that HDL particles from alcoholics are dysfunctional. This is important since it has been shown that it is not only the quantity of HDL particles, and thus HDL-cholesterol level in plasma, that matters, but their quality and impaired functionality as well. HDL from diabetic subjects also lose some of their antiatherogenic properties but a common feature of patients with diabetes type 2 is atherogenic dyslipidemia which is characterized exactly by low HDL-cholesterol and high triglycerides. Diabetic patients with such dyslipidemia are at particularly high CVD risk and the results of recent studies such as ACCORD-Lipid suggest that in them treatment of these lipid abnormalities may be beneficial. Treatment options with fibrates, particularly fenofibrate, and niacin are discussed based upon published trials, as well as combination therapy with these medicines and other lipid-lowering drugs.
    Lijec̆nic̆ki vjesnik 01/2011; 133(3-4):111-6.