Lijec̆nic̆ki vjesnik (Lijec Vjesn )

Publisher: National Library of Medicine (U.S.); National Science Foundation (U.S.); United States. Dept. of Health, Education, and Welfare; Zbor liječnika Hrvatske


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Publications in this journal

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    ABSTRACT: Based on the data provided by the Registry of the Department of Psychiatry, General Hospital Bjelovar, an epidemiological study of the hospital treated patients for the years 1980, 1985, 1990, 1995, 2000, 2005 and 2010 was made. In determining the diagnostic groups, the authors used the International Classification of Diseases ICD-10 and the World Health Organization's (WHO) recommendations, adjusting all diagnostic entities to that classification. The study sample consists of patients hospitalized at the Department of Psychiatry, General Hospital Bjelovar in the years mentioned above. Following parameters were analyzed: total number of hospitalizations, gender, age and hospitalization outcome--by diagnostic groups. What is noted is the decrease in the total number of psychiatric hospitalizations, the reduction of the proportion of men and women in the sample, and the decrease of mortality. In the observed period, the number of hospitalized patients diagnosed as alcoholics decreased, and the number of patients hospitalized with diagnosed as alcoholics decreased, and the number of patients hospitalized with diagnosed dementia, affective disorders, and critical conditions increased, while the number of the hospitalized schizophrenic patients has been oscillating. The main differences between the results of the initial and final year of the epidemiological study have been analyzed by the chi square test. The results of the epidemiological study shall help the evaluation, rational planning and further development in the protection of mental health of the inhabitants of the Bjelovar-Bilogora County.
    Lijec̆nic̆ki vjesnik 07/2014; Liječ Vjesn 2014;136:140–146.
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    ABSTRACT: Pregnancy in patients suffering from chronic renal disease is still a rare phenomenon due to a number of factors that impair fertility in such patients, in spite of a number of new treatment techniques that have been introduced recently, e.g. renal replacement therapy with biocompatible dialysis membranes, highflux dialyzers, erythropoietins, and new types of peritoneal dialysis and higher level of care for such patients. Yet, when pregnancy occurs, it is possible to provide a safe outcome for both the mother and fetus. However, optimal conditions for hemodialysis and peritoneal dialysis should be provided. The data on pregnancy in patients suffereing from chronic renal disease are rather scarce, and have been derived from registers of dialyzed patients from few countries. Unfortunately, no such data are known for the patients in Croatia. This review deals with the specific approach to hemodialysis and peritoneal dialysis in patients with pregnancy and end-stage renal disease. Particular attention is paid to specific problems associated with gestation, delivery and care for patients, with special reference to prenatal and neonatal care.
    Lijec̆nic̆ki vjesnik 03/2014; 124(3-4):82-8.
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    ABSTRACT: Objective: To estimate the prevalence of symptoms of asthma, allergic rhinitis/rhinoconjuctivitis and atopic eczema symptoms in the Međimurje County in Northwest Croatia. Subjects and methods: The study was undertaken between January and April 2005 among school children in 27 randomly selected elementary schools. Data were collected using standardized ISAAC written questionnaire Phase I. Results: A total of 3106 children participated in the study (7-9 yrs) with response rate 96,94%. 712 (22,9%) children had symptoms of allergic diseases at some time in their life. Estimated lifetime (ever) prevalence rates of symptoms were: wheezing 14,91% , allergic rhinitis symptoms 8,88% and atopic dermatitis symptoms 10,66%. Estimated 12-month prevalence rates were: wheezing 6,92%, allergic rhinitis symptoms 8,40%, allergic rhinoconjunctivitis 4,67%, and atopic dermatitis symptoms 5,76%. Conclusions: The results of this study show that Međimurje County is an area with moderate prevalence of atopic disease symptoms among the pediatric population.
    Lijec̆nic̆ki vjesnik 01/2014; 136(3-4):73-78.
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    ABSTRACT: To investigate the prevalence of anxiety and depression in the elderly inhabiting Koprivnica-Kri evci, Istria and Dubrovnik-Neretva Counties and their association with socio-demographic characteristics and healthcare utilisation. A cross-sectional cluster survey carried out in 2006, encompassing a total of 1,469 examinees aged 70+. The Hospital Anxiety and Depression (HAD) Scale was used to screen for self-reported symptoms of anxiety and depression, which were further associated with socio-demographic characteristics and healthcare utilisation. The elderly have shown a high prevalence of borderline and probable anxiety (43%) and depression (53%), and regional differences (p<0.001). The level of anxiety was higher in women than men (p<0.001); as for depression, no statistically significant gender-based differences were found. The prevalence of probable depression increases (p=0.034) and that of probable anxiety decreases (p=0.028) with age. Anxiety and depression are associated with increased use of specialist health care and more frequent hospitalizations. High prevalence of anxiety and depression in elderly is associated with sociodemographic characteristics and frequent use of health care.
    Lijec̆nic̆ki vjesnik 11/2013; 135(5-6):134-8.
  • Lijec̆nic̆ki vjesnik 07/2013; 135:150-155.
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    ABSTRACT: Hematopoietic stem cell transplantation (HSCT) has become an effective therapeutic option for the treatment of severe cases of autoimmune diseases (AD). Hematopoietic stem cells (HSC) can be collected from the patient (autologous), identical twin (syngenic) or HLA identical donor (allogenous). In allogenous transplantation autoagressive immunological effector cells are substituted with non-autoagressive cells of the donor. Possible graft versus host reaction (GVHD) makes this type of transplantation less attractive. On the other hand, autologous transplantation can induce the >resetting< of immunological clock without any fear of GVHD, but it requires previous conditioning. As an alternative option, transplantation ofmesenchymal stem cells (MSS) was developed. MSS has a strong immunosuppressive effect, while it doesn't require previous conditioning, nor does it induce GVHD. Due to the treatment related mortality, these therapeutic option should remain reserved for the most severe cases of AD. Nevertheless, they present a great opportunity for these patients, and even a chance for full recovery.
    Lijec̆nic̆ki vjesnik 07/2013; 135(5-6):150-5.
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    Lijec̆nic̆ki vjesnik 06/2013; VOL 2(SUPPL 3):155-157.
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    ABSTRACT: Intraductal papillary mucinous neoplasm (IPMN) of the pancreas is a relatively rare clinical entity with a main characteristic being mucus production. Extension of IPMN along pancretic ducts and mucus production lead to ductal obstruction and dilatation, resulting in recurrent episodes of acute pancreatitis. Molecular background of IPMN-a comprises several aberrations, with the K-ras gene mutation being the likely trigger that initiates further genetic changes. Due to its indolent nature, IPMN is most commonly diagnosed in the 7th decade of life. Depending on the histology type, IPMN has a malignant potential. Therefore, surgical therapy remains a "gold standard" of treatment. Insidious, slow progression of the disease and absence of symptoms in a certain number of patients makes diagnostic approach to this entity difficult. In this paper we present a patient with IPMN of the pancreas, in whom the episodes of acute pancreatitis had been present for 22 years.
    Lijec̆nic̆ki vjesnik 01/2012; 134(1-2):25-8.
  • Lijec̆nic̆ki vjesnik 01/2012;
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    ABSTRACT: Rosacea is a common skin disease of unknown etiology. The aim of the present paper is to explain the role of oxidative stress triggered by UV light and iron metabolism in the pathophysiology of rosacea. It was recently described that the number of ferritin positive cells was significantly higher in skin samples of rosacea patients compared to controls of healthy skin samples. The presence of ferritin was significantly higher in patients with the severe stage of disease. In addition, serum peroxide levels were significantly higher and serum total antioxidative potential levels were significantly lower in rosacea patients than in healthy controls. These results support the role of oxidative stress and affected metabolism of iron in etiology of rosacea. The higher presence of ferritin in skin cells of rosacea patients explains the exacerbation of symptoms by exposure to UV light, that releases ferritin free iron, which is fundamental in the generation of oxidative stress.
    Lijec̆nic̆ki vjesnik 01/2011; 133(7-8):288-91.
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    ABSTRACT: Malnutrition and sarcopenia are frequent in the hospitalized and institutionalized elderly. They have negative consequences on morbidity, mortality, function and quality of life. Enteral and parenteral nutrition are valid options in the malnourished elderly, both in the hospital and at home. Elderly patients share most indications and complications with adult patients, even though more focus needs to be put on function and quality of life than on mortality. In these guidelines we discuss the indications and special considerations of enteral and parenteral nutrition in geriatric patients as well as guidelines for clinical nutrition in three common pathologies in the elderly: decubital ulcers, dysphagia and dementia.
    Lijec̆nic̆ki vjesnik 01/2011; 133(9-10):299-307.
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    ABSTRACT: This paper presents the case of a patient suffering from atypical depression, with excessive daytime sleepiness, which was a suicidal equivalent. Patients who suffer from depression and sleep disorders can have an increased risk of suicidality, and to them should pay increased attention. Field of suicide as a means of resolving conflicts and unconscious mental escape from the reality of the obstacles, including sleep and daytime sleepiness, which may represent a form of "temporary suicide". The authors recommend that hypersomnia, daytime sleepiness in depressed patients and other sleep disorders should be treated as a potential risk factor for suicidal behavior.
    Lijec̆nic̆ki vjesnik 01/2011; 133(7-8):263-8.
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    ABSTRACT: The first annual meeting of Croatian physicians, with characteristics of a congress, was held in 1899 at the 25th anniversary of the Croatian Medical Association. From 1954 to 1996, during almost 60 years of existence of the Croatian Medical Association, ten congresses of the Association were held. The congresses were during the development of modern medicine devoted to different medical questions, including some problems of national pathology, of the structure and restructuring of health care. The work and the content of congresses were published in the proceedings except for the 8th Congress in 1987 and the 10th in 1996. By reading main lectures, invited lectures and free papers the knowledge of that period can be gained. Many papers are even today actual, even today it could be learned from them. With more details, using published proceedings the 9th congress and the 10th congress are described on the basis preserved program, of a brief report in home journal and ample preserved correspondence. The national medical congres dedicated to technology advancement and to numerous problems of national pathology may be actual even today. They could help to solve many problems of health care, contribute to its improvement and convey consensus on its further development.
    Lijec̆nic̆ki vjesnik 01/2011; 133(11-12):411-21.
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    ABSTRACT: Endoscopic mucosal resection (EMR) is a therapeutic method for removal of sesile premalignant lesions and intramucosal carcinoma of the gastrointestinal tract. No reports on EMR data in Croatia have been published yet. MATHERIALS AND METHODS: All patients included in the study were managed at the University Hospital Centre Zagreb between December 2006 and December 2008. EMR was performed using strip technique with submucosal injection of epinephrine (dilution with saline 1:5000-10000). EMR of sessile polypoid colorectal lesions was performed in 95 patients. The most common localisation of the disease was rectum (52 pts - 54.7%). In most patient size of the lesion was between 16-25 mm (43 pts - 45%). En-bloc resection was performed in 75 patients and piecemeal resection in the rest. Bleeding occurred immediately during the EMR in 5 pts (5.3%). Patohistological diagnosis revealed tubulovillous adenoma in 67 pts (70%). Invasive carcinoma was observed in 6 pts (6.3%) and intramucosal carcinoma in 20 pts (21%). On follow up, 73 pts (77%) did not show and sign of disease recurrence. Surgery was needed in 6 pts (6.3%) due to the diagnosis of invasive carcinoma. EMR is safe and reliable method with low risk of serious complications and acceptable recurrence rate.
    Lijec̆nic̆ki vjesnik 01/2011; 133(9-10):322-6.
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    ABSTRACT: Aging produces numerous physical and physiologic changes, which in turn alter nutritional requirements and affect nutritional status. The presence of chronic disease, and/or medications can enhance potential disparities between nutrient needs and dietary intake, leading to malnutrition. Indeed, research suggests that malnutrition is a common condition among the elderly. Therefore, regular nutritional assessment should be done as an integral part of healthcare for elderly. Also, it is important to take in consideration all determinants of geroanthropometry. The physiologic changes associated with aging affect requirement for several essential nutrients. In general, the requirement for many nutrients decreases, concomitant with the decrease in energy needs. However, some nutrients are needed in higher amounts. Additionally, various psychosocial and socioeconomic changes that often attend aging may also alter dietary intake. Dietary planning is important part of nutritional care in the elderly. Also, some elderly persons can benefit with dietary supplements and oral nutritional supplements (enteral formulas) which can be prescribed by diagnosed or threatening malnutrition. Croatian guidelines for nutrition in the elderly have been developed by interdisciplinary expert group of Croatian clinicians, gerontologists, anthropologists, nutritionists and other professionals involved with care for elderly population. The guidelines are based on evidence from relevant medical literature and clinical experience of working group.
    Lijec̆nic̆ki vjesnik 01/2011; 133(7-8):231-40.
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    ABSTRACT: Gastrointestinal stromal tumors are the most common mesenchymal tumors in gastrointestinal tract. They are often asymptomatic and discovered incidentally during endoscopic or barium studies. About 80% GISTs have a KIT (CD 117 antigen) gene mutation. Most affect exon 11, less commonly exon 9,13 or 17, that results in uncontrolled KIT signaling. This led to effective systemic therapies in the form of small molecule inhibitors of the receptor tyrosine kinase such as imatinib mesylat. With the purpose of providing standardized approach to rational and effective diagnostic and treatment algorithm in Croatia, a multidisciplinary session was organized. Results of the session are given in the form of Consensus guidelines.
    Lijec̆nic̆ki vjesnik 01/2011; 133(5-6):170-6.
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    ABSTRACT: Forty years have elapsed since the first total hip arthroplasty in Croatia, a procedure that has revolutionized treatment of a whole range of states resulting in hip dysfunction and has brought about significant improvements in restoring functional ability and quality of life of the affected patients. Modern progress in the development of the hip joint endoprosthetics is closely connected to a growing application ofbiotechnology resulting in implants with greatly improved biological, constructional and biomechanical properties as compared to the pioneering efforts. Additionally, developments of the surgical techniques, such as mini-invasive surgery or computer-assisted surgery enable almost ideal arthroplasty. Since 1970, when the first total hip arthroplasty was performed in Croatia, constant endeavor is being made in order to follow-up the ever evolving progress in the total hip endoprosthetics.
    Lijec̆nic̆ki vjesnik 01/2011; 133(9-10):343-51.

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