Lijec̆nic̆ki vjesnik (Lijec Vjesn )

Publisher: National Library of Medicine (U.S.); National Science Foundation (U.S.); United States. Dept. of Health, Education, and Welfare; Zbor liječnika Hrvatske


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Publications in this journal

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    ABSTRACT: Pregnancy in patients suffering from chronic renal disease is still a rare phenomenon due to a number of factors that impair fertility in such patients, in spite of a number of new treatment techniques that have been introduced recently, e.g. renal replacement therapy with biocompatible dialysis membranes, highflux dialyzers, erythropoietins, and new types of peritoneal dialysis and higher level of care for such patients. Yet, when pregnancy occurs, it is possible to provide a safe outcome for both the mother and fetus. However, optimal conditions for hemodialysis and peritoneal dialysis should be provided. The data on pregnancy in patients suffereing from chronic renal disease are rather scarce, and have been derived from registers of dialyzed patients from few countries. Unfortunately, no such data are known for the patients in Croatia. This review deals with the specific approach to hemodialysis and peritoneal dialysis in patients with pregnancy and end-stage renal disease. Particular attention is paid to specific problems associated with gestation, delivery and care for patients, with special reference to prenatal and neonatal care.
    Lijec̆nic̆ki vjesnik 03/2014; 124(3-4):82-8.
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    ABSTRACT: To investigate the prevalence of anxiety and depression in the elderly inhabiting Koprivnica-Kri evci, Istria and Dubrovnik-Neretva Counties and their association with socio-demographic characteristics and healthcare utilisation. A cross-sectional cluster survey carried out in 2006, encompassing a total of 1,469 examinees aged 70+. The Hospital Anxiety and Depression (HAD) Scale was used to screen for self-reported symptoms of anxiety and depression, which were further associated with socio-demographic characteristics and healthcare utilisation. The elderly have shown a high prevalence of borderline and probable anxiety (43%) and depression (53%), and regional differences (p<0.001). The level of anxiety was higher in women than men (p<0.001); as for depression, no statistically significant gender-based differences were found. The prevalence of probable depression increases (p=0.034) and that of probable anxiety decreases (p=0.028) with age. Anxiety and depression are associated with increased use of specialist health care and more frequent hospitalizations. High prevalence of anxiety and depression in elderly is associated with sociodemographic characteristics and frequent use of health care.
    Lijec̆nic̆ki vjesnik 11/2013; 135(5-6):134-8.
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    ABSTRACT: Hematopoietic stem cell transplantation (HSCT) has become an effective therapeutic option for the treatment of severe cases of autoimmune diseases (AD). Hematopoietic stem cells (HSC) can be collected from the patient (autologous), identical twin (syngenic) or HLA identical donor (allogenous). In allogenous transplantation autoagressive immunological effector cells are substituted with non-autoagressive cells of the donor. Possible graft versus host reaction (GVHD) makes this type of transplantation less attractive. On the other hand, autologous transplantation can induce the >resetting< of immunological clock without any fear of GVHD, but it requires previous conditioning. As an alternative option, transplantation ofmesenchymal stem cells (MSS) was developed. MSS has a strong immunosuppressive effect, while it doesn't require previous conditioning, nor does it induce GVHD. Due to the treatment related mortality, these therapeutic option should remain reserved for the most severe cases of AD. Nevertheless, they present a great opportunity for these patients, and even a chance for full recovery.
    Lijec̆nic̆ki vjesnik 07/2013; 135(5-6):150-5.
  • Lijec̆nic̆ki vjesnik 07/2013; 135:150-155.
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    Lijec̆nic̆ki vjesnik 06/2013; VOL 2(SUPPL 3):155-157.
  • Lijec̆nic̆ki vjesnik 01/2012;
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    ABSTRACT: Intraductal papillary mucinous neoplasm (IPMN) of the pancreas is a relatively rare clinical entity with a main characteristic being mucus production. Extension of IPMN along pancretic ducts and mucus production lead to ductal obstruction and dilatation, resulting in recurrent episodes of acute pancreatitis. Molecular background of IPMN-a comprises several aberrations, with the K-ras gene mutation being the likely trigger that initiates further genetic changes. Due to its indolent nature, IPMN is most commonly diagnosed in the 7th decade of life. Depending on the histology type, IPMN has a malignant potential. Therefore, surgical therapy remains a "gold standard" of treatment. Insidious, slow progression of the disease and absence of symptoms in a certain number of patients makes diagnostic approach to this entity difficult. In this paper we present a patient with IPMN of the pancreas, in whom the episodes of acute pancreatitis had been present for 22 years.
    Lijec̆nic̆ki vjesnik 01/2012; 134(1-2):25-8.
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    ABSTRACT: Colorectal cancer is the third most common malignant tumour in males and the fourth most common malignancy in women in the Republic of Croatia. It is usually manifested as stool forming disorders, feeling that bowel does not empty completely, finding blood in the stool, weight loss and fatigue. In-time diagnosis, confirmed by pathohistological findings, is cornerstone of successful treatment. The decision about treatment is made based on clinical assessment of disease stage and other risk factors, after completion of the diagnostic process. Depending on that, treatment options include surgery, the application of systemic therapy (chemotherapy, immunotherapy) and radiotherapy. The following text presents the clinical guidelines in order to standardize procedures and criteria for the diagnosis, management, treatment and monitoring of patients with colorectal cancer in the Republic of Croatia.
    Lijec̆nic̆ki vjesnik 01/2011; 133(11-12):366-9.
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    ABSTRACT: This paper presents the case of a patient suffering from atypical depression, with excessive daytime sleepiness, which was a suicidal equivalent. Patients who suffer from depression and sleep disorders can have an increased risk of suicidality, and to them should pay increased attention. Field of suicide as a means of resolving conflicts and unconscious mental escape from the reality of the obstacles, including sleep and daytime sleepiness, which may represent a form of "temporary suicide". The authors recommend that hypersomnia, daytime sleepiness in depressed patients and other sleep disorders should be treated as a potential risk factor for suicidal behavior.
    Lijec̆nic̆ki vjesnik 01/2011; 133(7-8):263-8.
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    ABSTRACT: Because of development of laparoscopic surgery and by knowing of its pathophysiological effects on organism, indications for laparoscopic surgery have become more extensive, so this method is today used for therapeutic and diagnostic procedures. Although ventriculoperitoneal shunt is not normally considered a contraindication for laparoscopic surgery, pneumoperitoneum is described as a cause of raised intracranial pressure. Since 1992 when the first laparoscopic cholecystectomy was done at the University Department of Surgery of Sveti Duh Clinical Hospital in Zagreb, three patients with implanted ventriculoperitoneal shunt were managed successfully laparoscopically. In all three patients, there were no complications during and after the surgery. In this paper we present our experience of three cases and short review of the literature.
    Lijec̆nic̆ki vjesnik 01/2011; 133(7-8):260-2.
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    ABSTRACT: Rosacea is a common skin disease of unknown etiology. The aim of the present paper is to explain the role of oxidative stress triggered by UV light and iron metabolism in the pathophysiology of rosacea. It was recently described that the number of ferritin positive cells was significantly higher in skin samples of rosacea patients compared to controls of healthy skin samples. The presence of ferritin was significantly higher in patients with the severe stage of disease. In addition, serum peroxide levels were significantly higher and serum total antioxidative potential levels were significantly lower in rosacea patients than in healthy controls. These results support the role of oxidative stress and affected metabolism of iron in etiology of rosacea. The higher presence of ferritin in skin cells of rosacea patients explains the exacerbation of symptoms by exposure to UV light, that releases ferritin free iron, which is fundamental in the generation of oxidative stress.
    Lijec̆nic̆ki vjesnik 01/2011; 133(7-8):288-91.
  • Lijec̆nic̆ki vjesnik 01/2011;
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    ABSTRACT: Studies were identified on internet by searching on address: with criteria that studies should be placebo-controlled and randomized in trials of alpha-blockers in chronic category III prostatitis evaluated by symptom-score NIH-CPSI. From 13 clinical studies three were excluded because of not using NIH-CPSI, three were in Chinese language and two were congress abstracts. Analysed were five studies with four or five Jadad scale including 563 patients. Alpha-blockers alfuzosin, terazosin, tamsulosin and doxazosin have been used through 6 weeks and 6 months. Better results were accomplished by less selective alpha-blockers alfuzosin, terazosin and doxazosin through 3-6 months in patients having higher NIH-CPSI score and higher voiding score.
    Lijec̆nic̆ki vjesnik 01/2011; 133(5-6):177-80.
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    ABSTRACT: Aging produces numerous physical and physiologic changes, which in turn alter nutritional requirements and affect nutritional status. The presence of chronic disease, and/or medications can enhance potential disparities between nutrient needs and dietary intake, leading to malnutrition. Indeed, research suggests that malnutrition is a common condition among the elderly. Therefore, regular nutritional assessment should be done as an integral part of healthcare for elderly. Also, it is important to take in consideration all determinants of geroanthropometry. The physiologic changes associated with aging affect requirement for several essential nutrients. In general, the requirement for many nutrients decreases, concomitant with the decrease in energy needs. However, some nutrients are needed in higher amounts. Additionally, various psychosocial and socioeconomic changes that often attend aging may also alter dietary intake. Dietary planning is important part of nutritional care in the elderly. Also, some elderly persons can benefit with dietary supplements and oral nutritional supplements (enteral formulas) which can be prescribed by diagnosed or threatening malnutrition. Croatian guidelines for nutrition in the elderly have been developed by interdisciplinary expert group of Croatian clinicians, gerontologists, anthropologists, nutritionists and other professionals involved with care for elderly population. The guidelines are based on evidence from relevant medical literature and clinical experience of working group.
    Lijec̆nic̆ki vjesnik 01/2011; 133(7-8):231-40.
  • Lijec̆nic̆ki vjesnik 01/2011; 133(1-2):1-14.
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    ABSTRACT: Surgery does not start with the incision and end with skin suturing. Successful surgical outcome depends on close interaction between the anesthesiology, surgery and intensive care units (ICU). Adequate patient monitoring is essential part of all aforementioned departments. Using adequate hemodynamic and neurologic monitoring, less invasive anaesthesia with less invasive cardiac and vascular surgery can be performed safely, leading to better surgical results, greater patient comfort and satisfaction, and reduced hospital stay.
    Lijec̆nic̆ki vjesnik 01/2010; 132 Suppl 1:9-10.
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    ABSTRACT: Biofilm formation is a crucial step in the pathogenesis of many subacute and chronic bacterial infections, including foreign body-related infections. Biofilms are difficult to eradicate with conventional antimicrobial agents. Bacterial biofilms have several potential antimicrobial resistance mechanisms. Persister cells play a major role in the tolerance of biofilm bacteria to antimicrobial agents. The most common microorganisms responsible for about two thirds of infections with foreign material are biofilm-forming bacteria such as staphylococci (Staphylococcus aureus, S. epidermidis, S. lungdunensis), followed by Pseudomonas aeruginosa and Enterococcus spp, as well as fungal infections such as Candida sp. Preventing early colonisation is a good strategy for reducing morbidity and furthermore, reducing biofilm-associated infection reduces the need for antibiotic use.
    Lijec̆nic̆ki vjesnik 01/2010; 132 Suppl 1:24-6.

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