Genetika (Genetika)

Publisher: Springer Verlag

Journal description

Russian version of Russian Journal of Genetics (1022-7954).

Current impact factor: 0.37

Impact Factor Rankings

2015 Impact Factor Available summer 2016
2011 Impact Factor 0.44
1998 Impact Factor 0.326
1997 Impact Factor 0.306

Impact factor over time

Impact factor

Additional details

5-year impact 0.00
Cited half-life 3.60
Immediacy index 0.06
Eigenfactor 0.00
Article influence 0.00
Website Genetika website
ISSN 0016-6758

Publisher details

Springer Verlag

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Publications in this journal

  • Genetika 11/2015; 51(11):1297-1300. DOI:10.7868/S0016675815110144

  • Genetika 11/2015; 51(11):1264-1272. DOI:10.7868/S0016675815110028
  • M. Xiao · H. Xia · F. Bao ·
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    ABSTRACT: The isolation and development of 15 polymorphic dinucleotide microsatellite loci were described for Ophicephalus argus from the Huaihe River. All loci were polymorphic in the 30 individuals tested. The number of alleles per variable locus ranged from nine to seventeen, with a mean of 12.00. These novel microsatellite loci showed high level of polymorphism. Observed and expected heterozygosities ranged from 0.793 to 0.929 and from 0.841 to 0.952, respectively. Two loci were found deviated from HWE in the sampled population after Bonferroni correction. These microsatellite loci will be useful for revealing population structure, genetic diversity, and phylogeography of Ophicephalus argus.
    Genetika 10/2015; 51(10):1212-1216. DOI:10.7868/S0016675815090131
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    ABSTRACT: The mitochondrial DNA (mtDNA) ATPase 8/6 gene has been used in phylogenetic as well as in phylogeographic studies along with other mtDNA markers. In this study, ATPase gene sequences were used to assess the genetic structuring and phylogeographic patterns in Channa striata. Out of 884 nucleotide positions generated in ATPase 8/6 genes, 76 were polymorphic. The study suggested 23 unique haplotypes from 67 individuals of nine populations collected from different riverine systems of India. The ATPase 8/6 sequence revealed highest haplotype as well as nucleotide diversities in Imphal River population and lowest diversities in Tapti River population. The pattern of genetic diversity and haplotype network indicated distinct mitochondrial lineages for Chaliyar population, whereas mismatch distribution strongly suggested a population expansion in mid pleistocene epoch (0.4 Mya) with distinct genetic structuring in C. striata. The baseline information on genetic variation and the population sub-structuring would facilitate conservation and management of this important snakehead murrel.
    Genetika 10/2015; 51(10):1171-1183. DOI:10.7868/S0016675815100045
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    ABSTRACT: Downy mildew of cucumber (Cucumis sativus L.), caused by Pseudoperonospora cubensis (Berk. et Curt.) Rostovzev, is one of the most important foliar diseases of cucurbit crops. Two parental lines resistant PI 197085, susceptible PI 175695 and their F2 generation were used in our study. Inheritance of resistance to Pseudoperonospora cubensis in PI 197085 was quantitative. JoiMap 4.1 and MapQTL 6.0 software was used for a linkage groups construction and QTL mapping. Three QTL were detected: DM1, DM2, DM3. The loci were mapped on chromosome 5 of cucumber genome. Molecular analysis confirmed results of classical quantitative genetics indicating that resistance to Pseudoperonospora cubensis in PI 197085 is polygenic trait.
    Genetika 10/2015; 51(10):1134-1140. DOI:10.7868/S0016675815090118
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    ABSTRACT: Umbilical hernia (UH) is a complex disorder caused by both genetic and environmental factors. UH brings animal welfare problems and severe economic loss to the pig industry. Until now, the genetic basis of UH is poorly understood. The high-density 60K porcine SNP array enables the rapid application of genome-wide association study (GWAS) to identify genetic loci for phenotypic traits at genome wide scale in pigs. The objective of this research was to identify susceptibility loci for swine umbilical hernia using the GWAS approach. We genotyped 478 piglets from 142 families representing three Western commercial breeds with the Illumina PorcineSNP60 BeadChip. Then significant SNPs were detected by GWAS using ROADTRIPS (Robust Association-Detection Test for Related Individuals with Population Substructure)software base on a Bonferroni corrected threshold (P = 1.67E-06) or suggestive threshold (P = 3.34E-05) and false discovery rate (FDR = 0.05). After quality control, 29924 qualified SNPs and 472 piglets were used for GWAS. Two suggestive loci predisposing to pig UH were identified at 44.25MB on SSC2 (rs81358018, P = 3.34E-06, FDR = 0.049933) and at 45.90MB on SSC17 (rs81479278, P = 3.30E-06, FDR = 0.049933) in Duroc population, respectively. And no SNP was detected to be associated with pig UH at significant level in neither Landrace nor Large White population. Furthermore, we carried out a meta-analysis in the combined purebreed population containing all the 472 piglets. rs81479278 (P = 1.16E-06, FDR = 0.022475) was identified to associate with pig UH at genome-wide significant level. SRC was characterized as plausible candidate gene for susceptibility to pig UH according to its genomic position and biological functions. To our knowledge, this study gives the first description of GWAS identifying susceptibility loci for umbilical hernia in pigs. Our findings provide deeper insights to the genetic architecture of umbilical hernia in pigs.
    Genetika 10/2015; 51(10):1163-1170. DOI:10.7868/S0016675815100100
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    ABSTRACT: Vernalization plays a key role in the bolting and flowering of Chinese cabbage (Brassica rapa L. ssp. pekinensis). Plants can switch from vegetative to reproductive growth and then bolt and flower under low temperature induction. The economic benefits of Chinese cabbage will decline significantly when the bolting happens before the vegetative body fully grows due to a lack of the edible value. It was found that continuous seedling breeding reduced the heading of Chinese cabbage and led to bolt and flower more easily. In the present study, two inbred lines, termed A161 and A105, were used as experiment materials. These two lines were subjected to vernalization and formed four types: seeds-seedling breeding once, seedling breeding twice, seedling breeding thrice and normal type. Differences in plant phenotype were compared. DNA methylation analysis was performed based on MSAP method. The differential fragments were cloned and analyzed by qPCR. Results showed that plants after seedling breeding thrice had a loosen heading leaves, elongated center axis and were easier to bolt and flower. It is suggested that continuous seedling breeding had a weaker winterness. It was observed that genome methylation level decreased with increasing generation. Four differential genes were identified, short for BraAPC1, BraEMP3, BraUBC26 and BraAL5. Fluorescent qPCR analysis showed that expression of four genes varied at different reproduction modes and different vernalization time. It is indicated that these genes might be involve in the development and regulation of bolting and flowering of plants. Herein, the molecular mechanism that continuous seedling breeding caused weaker winterness was analyzed preliminarily. It plays an important guiding significance for Chinese cabbage breeding.
    Genetika 08/2015; 51(8):905-914. DOI:10.7868/S0016675815080111
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    ABSTRACT: Rice amylose content (AC) is a key determinant for grain end-use quality attributes. The base substitution ((G → T) at +1 loci of the first intron (In1) of Waxy (Wx), a major gene controlling AC in rice, results in decreased AC. A new SNP typing method of Wx In1 based on polymerase chain reaction with confronting two-pair primers (PCR-CTPP) was reported here: first its practicability was confirmed by 23 varieties with known SNP and AC; and then the segregation ratio at target SNP loci were checked and it fitted well for 1: 2: 1 single gene segregation; at last SNP typing and AC assay with 150 mini core collections (MCC) in China showed that average AC of 53 G type varieties (22.5%) was significantly higher than that of 97 T type varieties (13.7%) (p < 0.01) and the target SNP loci explained 77.8% AC variation. So this method could be used to estimate AC of rice variety roughly or in marker-assisted breeding, that is, using variety with known and desired AC as Wx allele donor parent and aided with crossbreed, backcross and marker-assisted selection (MAS) reported here, rice breeders could improve AC of varieties with comprehensively excellent performance to meet special end-products.
    Genetika 07/2015; 51(7):787-791. DOI:10.7868/S001667581506003X
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    ABSTRACT: Integration of the concepts of symbiogenesis and synthetic evolutionary theory is the main path for the development of evolutionary biology. It is based on the analysis of cooperative adaptations that evolve under the impact of symbiotic-specific selective pressures responsible for the formation of super-species hereditary systems--metagenomes, symbiogenomes, and hologenomes. The genetic integration of nonrelated organisms (symbiogenesis) is determined by the inheritance of microsymbionts by hosts resulted in the complication of mutualistic interactions according to the scheme: pleiotropic symbiosis --> mutual partner's exploitation --> interspecies altruism. This evolution may result in the loss of genetic individuality in microsymbionts; this loss is expressed as a deep reduction in their genomes. A significant number of these may be exported to the host, resulting in the transformation of symbiotic systems into novel, genetically integral organisms.
    Genetika 06/2015; 51(6):658-67. DOI:10.1134/S1022795415050051
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    ABSTRACT: The methylation of CpG islands in promoter regions, together with the interaction of miRNAs with the mRNAs of their target genes on the posttranscriptional level, are complex epigenetic mechanisms that perform the delicate and dynamic regulation of genes and signal transduction pathways in the cell. This review summarizes the results obtained by the authors, as well as the literature data, on the roles of methylation in regulating the protein-coding genes of chromosome 3 and a number of miRNA genes in clear-cell renal cell carcinomas. The results are based on the use of genomic NotI-microarrays (which allow the identification of both methylation and deletions in genes containing CpG islands) and on some other approaches. The application of NotI-microarray technology to the analysis of the chromosome-3 short arm, a region of frequent deletions in tumors, gave us the opportunity to identify many novel genes associated with kidney cancer pathogenesis. The relationship between alterations in the expression leyels and methylation of chromosome 3 genes, kidney cancer progression, and metastasis was shown. New microRNAs involved in kidney cancer pathogenesis were identified as well. The functions of microRNA genes methylated in kidney cancer were discussed.
    Genetika 06/2015; 51(6):668-84. DOI:10.1134/S1022795415050026
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    ABSTRACT: We have shown previously that the polymorphic structure of the limk1 gene in Drosophila leads to changes in LIMK1 content and to defects in courtship behavior, sound production, and learning/memory. The results of the present study of three wild-type strains and mutant agn ts3 with altered limk1 structure demonstrate that long-term memory is normal in Canton-S and Oregon-R but is impaired in Berlin and drastically suppressed in agn ts3 . This temperature-sensitive mutant carries the S-element from the Tc1/mariner family insertion near the dlimk1 3′-UTR and, compared to Canton-S, has a reverse pCREB distribution in adult neuromuscular junctions (NMJ) of the second dorsal imago nerve before and after learning. Moreover, only agn ts3 demonstrates amyloid-like aggregate formation in NMJ. This suggests that this impedes pCREb transport and thereby impairs the formation of short- and long-term memory.
    Genetika 06/2015; 51(6):685-93. DOI:10.1134/S1022795415060071
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    ABSTRACT: Because of the advantages of EST-SSR markers, it has been employed as powerful markers for genetic diversity analysis, comparative mapping and phylogenetic studies. In this study, a total of 429,869 tobacco (Nicotiana tabacum L.) ESTs were downloaded from the public databases, which offers an opportunity to identify SSRs in ESTs by data mining, and 38,165 SSRs were identified from 379,967 uni-ESTs with the frequency of one SSR per 5.52 kb. Mono- and tri-nucleotide repeat motifs were the dominant repeat types, accounting for 40.53 and 34.51% of all SSRs, respectively. After eliminating mononucleotide-containing sequences, 86 pairs of primers were designed to amplify in four tobacco accessions. Only 15 primers (17.44%) showed polymorphism, and then they were further used to assess genetic diversity of 20 tobacco accessions. Unweighted pair-group method with arithmetic average dendrograms (UPGMA) and principal coordinates analysis plots (PCA) revealed genetic differentiation between N. rustica and N. tabacum, and between oriental tobacco and other accessions of N. tabacum. The present study reported the development of EST-SSR markers in tobacco by exploiting EST databases, and confirmed the effective way to develop markers. These EST-SSRs can serve in studies on cultivar identification, genetic diversity analysis, and genetics in tobacco.
    Genetika 06/2015; 51(6):694-703. DOI:10.7868/S001667581502006X
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    ABSTRACT: Based on sequence variation of the mtDNA cyt b gene, an analysis of graylings introduced from the Arctic Ocean basin (Selenga River basin) into one of the rivers of Central Asian inland basin (Baydrag Goal River of the Valley of Lakes basin) was carried out. Morphological and molecular genetic identification was performed, and it was established that the introduced species corresponded to the Baikal grayling. The relationships among Central Asian grayling species are discussed.
    Genetika 06/2015; 51(6):704-10. DOI:10.1134/S1022795415060149