Archives of Oral Biology (ARCH ORAL BIOL)
The Archives of Oral Biology publishes papers concerned with advances in knowledge of every aspect of the oral and dental tissues and bone over the whole range of vertebrates, whether from the standpoint of anatomy, bacteriology, biophysics, chemistry, DNA biotechnology, epidemiology, genetics, immunology, molecular biology, palaentology, pathology, physiology or otherwise.
- Impact factor1.6Show impact factor historyHide impact factor history
- WebsiteArchives of Oral Biology website
Other titlesArchives of oral biology
Material typePeriodical, Internet resource
Document typeJournal / Magazine / Newspaper, Internet Resource
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Publications in this journal
Article: Effect of dentine matrix proteins on human endometrial adult stem-like cells: In vitro regeneration of odontoblasts cellsArchives of Oral Biology 01/2013;
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ABSTRACT: Objective The aim of the present study was to describe the changes in the activity of ALDH3A1 in saliva in relation to the menstrual cycle and pregnancy. We also measured major salivary antioxidants, salivary peroxidase (SPO) activity and uric acid (UA) concentration. Design Fasting saliva samples were collected from 63 women with uncomplicated pregnancies and from 39 healthy women of reproductive age, but not pregnant. Saliva samples were also collected from 10 healthy women with regular menstrual cycles in the early follicular, the mid-cycle and the mid-luteal phase during one menstrual cycle. SPO and ALDH3A1 activity was determined fluorimetrically, whereas UA concentration photometrically. Results The ALDH3A1 did not vary significantly among phases of menstrual cycle. However, the enzyme activity decreased with the length of pregnancy and in the third trimester is significantly lower than that in the saliva of non-pregnant women. Conclusions Lower concentration of UA and in the third trimester the activity of ALDH3A1 in saliva of pregnant women could be a risk factor of, e.g. oral pathologies.Archives of Oral Biology 12/2012;
Archives of Oral Biology 01/2012;
Article: Sema BECERİK, Nazan ÖZSAN, Ali GÜRKAN, Veli Özgen ÖZTÜRK, Gül ATİLLA, Gülnur EMİNGİL Toll like receptor 4 and membrane-bound CD14 expression in gingivitis, periodontitis and CsA-induced gingival overgrowth. Arhives of Oral Biology, 2011; 56: 456-465.Archives of Oral Biology 01/2011;
Article: Oya TÜRKOĞLU, Afig BERDELİ, Gülnur EMİNGİL, Gül ATİLLA A novel p.S34N mutation of CAMP gene in patients with periodontal disease. Arhives of Oral Biology, 2011; 56: 573-579.Archives of Oral Biology 01/2011;
Article: Gülnur EMİNGİL, Beral AFACAN, Taina TERVAHARTIALA, Hüseyin TÖZ, Gül ATİLLA, Timo SORSA GCF and serum myeloperoxidase and matrix metalloproteinase-13 levels in renal transplant patients. Arhives of Oral Biology, 2010; 55: 719-727.Archives of Oral Biology 01/2010;
Article: In vitro antimicrobial effect of bacteriocin PsVP-10 in combination with chlorhexidine and triclosan against Streptococcus mutans and Streptococcus sobrinus strainsArchives of Oral Biology 01/2009; 54:230-234.
Article: Ali GÜRKAN, Gülnur EMİNGİL, Buket HAN SAYGAN, Gül ATİLLA, Timur KÖSE, Haluk BAYLAS, Afig BERDELİ Angiotensin-converting enzyme (ACE), angiotensinogen (AGT), and angiotensin II type 1 receptor (AT1R) gene polymorphisms in generalized aggressive periodontitis.Arhives of Oral Biology, 2009; 54: 337-344.Archives of Oral Biology 01/2009;
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ABSTRACT: The purpose of this study was to investigate whether alpha-galactosidase activity is present in whole and glandular saliva and whether alpha-galactosidase activity depends on blood type and secretor status. For the first experiments, 30 healthy participants (15 men, 15 women; mean age, 24.2+/-1.5 years) who were 10 A, 10 B, and 10 O blood type subjects were included. alpha-Galactosidase activity in unstimulated whole saliva (UWS) was assayed by using 4-methylumbelliferyl-alpha-d-galactopyranoside as a substrate. Total protein concentration was determined by bicinchoninic acid assay. The secretor status of the blood group antigens was determined by immunoblotting. alpha-Galactosidase activity in UWS according to gender, blood type, secretor status, sample clarification, and buffer was investigated. Daily variations of alpha-galactosidase activity and alpha-galactosidase isozyme activity were also investigated. For the second experiments, 10 healthy blood type B participants (5 men, 5 women; mean age, 27.0+/-2.7 years) were enrolled. alpha-Galactosidase activity in whole and glandular saliva was investigated. alpha-Galactosidase activity was detected in UWS and was mainly isozyme A activity. There was no difference in alpha-galactosidase activity according to gender, blood type, and secretor status. alpha-Galactosidase activity in UWS was higher in unclarified samples than in clarified ones and showed wide daily variations. alpha-Galactosidase activity in whole saliva was significantly higher than that in glandular saliva. alpha-Galactosidase activity which is mainly isozyme A activity was detected in human whole and glandular saliva. alpha-Galactosidase activity in UWS did not differ according to blood type and secretor status.Archives of Oral Biology 10/2008; 53(9):842-8.
Article: Development of the pioneer sympathetic innervation into the dental pulp of the mouse mandibular first molar.[show abstract] [hide abstract]
ABSTRACT: Our goal was to study the development of pioneer sympathetic innervation of dental pulp of mouse mandibular first molar. We used double fluorescent immunohistochemistry with tyrosine hydroxylase (TH) and anti-medium-chain neurofilament (2H3) antibodies to detect sympathetic and sensory nerve fibres. Serial sections of whole teeth from postnatal days (PN) 0-14, trigeminal and sympathetic superior cervical ganglia of PN 15 mice were examined with confocal microscope. There were two main findings. The unexpected finding was that 2H3 antibody was specific only for sensory nerve fibres and neurons and failed to stain either sympathetic nerve fibres or neurons. The main finding was that although both sympathetic and sensory nerve fibres were already seen near the tooth germ at the newborn stage, the pioneer sympathetic nerve fibres were first observed in the dental pulp only after the onset of root formation on day 9, in contrast to sensory nerve fibres which entered the tooth already on day 4. Pioneer sympathetic innervation of dental pulp starts on postnatal day 9 and follows sensory innervation. This indicates differential developmental regulation of the initial sensory and sympathetic innervation of teeth and provides essential background data for further studies on the molecular regulation of pulp innervation.Archives of Oral Biology 10/2008; 53(9):865-73.
Article: Histochemistry of nerve fibres double labelled with anti-TRPV2 antibodies and sensory nerve marker AM1-43 in the dental pulp of rat molars.[show abstract] [hide abstract]
ABSTRACT: AM1-43 can label sensory nerve fibres and sensory neurons. Permeation of non-selective cation channels of the nerve cell membrane is suggested to be the mechanism responsible for labelling. To identify these channels, two candidates, TRPV1 and TRPV2 were examined by immunocytochemistry in the dental pulp and trigeminal ganglion of rats injected with AM1-43. A part of AM1-43-labelled nerve fibres was also positive for anti-TRPV2 antibody but negative for anti-TRPV1 antibody in the dental pulp. In the trigeminal ganglion, a part of the neuron showed both bright AM1-43 labelling and anti-TRPV2 immunolabelling, but neurons double labelled with AM1-43 and TRPV1 were rare. These results suggest that TRPV2 channels, but not TRPV1 channels, contribute to the fluorescent labelling of AM1-43 in the dental pulp.Archives of Oral Biology 10/2008; 53(9):859-64.
Article: Expression of heat shock protein 47 in the periodontal ligament during orthodontic tooth movement.[show abstract] [hide abstract]
ABSTRACT: The aim of this study was to investigate the kinetics of heat shock protein 47 (HSP47) and proliferating cell nuclear antigen (PCNA) immunohistochemistry in periodontal ligament (PDL) cells during orthodontic tooth movement in a mouse model. An orthodontic appliance was set between the upper incisors and the upper left first molar. The mice were killed 2, 6 and 10 days after initiation of orthodontic tooth movement. Computer-assisted image analysis was used to compare the quantitative expression of HSP47 in the PDL. HSP47 expression was significantly higher on the tension side 2 days after application of the appliance, whereas no significant change was observed on the pressure side at any time point. Furthermore, the PCNA labelling indices of PDL cells were increased significantly on the tension side 6 and 10 days after application of the appliance, and on the pressure side 2, 6 and 10 days after application of the appliance. These data suggest that collagen is metabolised predominantly on the tension side, and that PDL cells actively proliferate on both the tension and pressure sides during orthodontic tooth movement.Archives of Oral Biology 10/2008; 53(9):890-5.
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ABSTRACT: The goal of this study was to assess the effect of type 1 diabetes mellitus (T1DM) on the craniofacial growth and skeletal maturation using the STZ-DM rat model. Experimental T1DM was induced in 3-week-old male Wistar rats by a single dose of 60 mg/kg body weight of streptozotocin (STZ). Lateral and dorsoventral X-rays of the head were taken at the age of 7 weeks. The X-rays were scanned, digitised and selected linear distances were measured and analysed statistically. In STZ-DM statistical analysis of results revealed a reduction in growth of most of the linear measurements in the neurocranium and mandible by X-ray analysis, and all measurements were significantly lower in viscerocranium. Uncontrolled T1DM reduces craniofacial growth, resulting in retardation of skeletal development.Archives of Oral Biology 10/2008; 53(9):819-25.
Article: Iron chelator differentially activates macrophage inflammatory protein-3alpha/CCL20 in immortalized and malignant human oral keratinocytes.[show abstract] [hide abstract]
ABSTRACT: Macrophage inflammatory protein-3alpha (MIP-3alpha or CCL20) is an intriguing molecule in cancer immunotherapy, but MIP-3alpha expression and signalling are not well understood in oral cancer cells. We investigated CCL20 expression and signal transduction by treating immortalized human oral keratinocyte (IHOK) and oral cancer (HN4) cells with deferoxamine (DFO) and examined the mRNA expression of CCL20 using RT-PCR and ELISA. IHOK and HN4 cells treated with DFO showed increased mRNA and protein expression of CCL20, and the upregulation of DFO-induced CCL20 expression was higher in IHOK cells than in HN4 cells. Selective inhibitors of p38 and ERK1/2 abolished DFO-induced CCL20 expression in both IHOK and HN12 cells, and p38 and ERK1/2 inhibitors prevented DFO-induced degradation of I-kappaB and NF-kappaB activation. Activation of c-fos and c-jun also occurred following DFO treatment in IHOK and HN4 cells. Collectively, these results suggest that DFO-induced MIP-3alpha, which is involved in the MAP kinase, c-fos, c-jun, and NF-kappaB pathways, may be an important mediator of the antitumour immune response in oral keratinocytes and warrants consideration as a target molecule for oral cancer treatment.Archives of Oral Biology 10/2008; 53(9):801-9.
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ABSTRACT: Podoplanin is one of the most highly expressed lymphatic-specific genes. Here, we report the distribution of cells expressing podoplanin in mouse salivary glands. We immunohistochemically investigated the distribution of cells expressing podoplanin in mouse major salivary glands by laser-scanning microscopy. The expression of endothelial cell marker PECAM-1 was tested to discriminate lymphatic endothelium from salivary gland cells, and myoepithelial cells were identified by an antibody for P-cadherin. The podoplanin expression was rarely found in acini of the parotid gland but clearly found at the basal portion of acini in the submandibular and sublingual glands. The number of portion reacted with anti-podoplanin is greater in the sublingual gland than in the submandibular gland. The expression was also found at the basal portion of ducts in all major salivary glands. The P-cadherin expression was rarely found in acini of the parotid gland but found in acini of the sublingual gland and on ducts in parotid and sublingual glands, corresponding to the area of podoplanin expression. It was suggested that the acinar and myoepithelial cells in the salivary glands have the ability to express podoplanin, and that the expression may be concerned with the mucous saliva excretion.Archives of Oral Biology 10/2008; 53(9):835-41.
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ABSTRACT: The hydrodynamic theory of dentine hypersensitivity proposes that external stimuli cause dentinal fluid movement within dentinal tubules thereby triggering mechanosensitive nerves and eliciting a pain response. The aim of this study was to employ X-ray microtomography (XMT) to monitor diffusion of caesium acetate through dentine to investigate the extent to which transport occurs within the primary tubules compared to that through branched microtubules believed to run perpendicular to the direction of the primary dentinal tubules. 2.0-mm thick coronal dentine disks masked to leave half of the upper surface exposed were imaged by XMT, initially in water, which was then replaced with an aqueous solution of 0.50 mol l(-1) caesium acetate. Further XMT images were acquired after 1 and 6 days immersion. The XMT images were used to measure the change in the X-ray linear attenuation coefficient resulting from caesium acetate ingress into dentine. There was clearly considerable ingress of caesium acetate into the dentine lying below the exposed surface, but considerably less beneath the sealed surface, suggesting that diffusive transport occurs predominantly in the direction of the primary dentinal tubules, with no significant lateral transport. Primary tubules are clearly the dominant transmission route for triggering the mechanosensitive nerves present at the dentine-pulp interface, and for delivery of nerve desensitising agents.Archives of Oral Biology 09/2008; 53(8):736-43.
Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.
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