Archives of Oral Biology (ARCH ORAL BIOL)

Publisher: European Organization for Research on Fluorine and Dental Caries Prevention, Elsevier

Journal description

The Archives of Oral Biology publishes papers concerned with advances in knowledge of every aspect of the oral and dental tissues and bone over the whole range of vertebrates, whether from the standpoint of anatomy, bacteriology, biophysics, chemistry, DNA biotechnology, epidemiology, genetics, immunology, molecular biology, palaentology, pathology, physiology or otherwise.

Current impact factor: 1.88

Impact Factor Rankings

2015 Impact Factor Available summer 2015
2013 / 2014 Impact Factor 1.88
2012 Impact Factor 1.549
2011 Impact Factor 1.603
2010 Impact Factor 1.463
2009 Impact Factor 1.649
2008 Impact Factor 1.379
2007 Impact Factor 1.554
2006 Impact Factor 1.655
2005 Impact Factor 1.288
2004 Impact Factor 1.158
2003 Impact Factor 1.098
2002 Impact Factor 1.047
2001 Impact Factor 0.973
2000 Impact Factor 0.845
1999 Impact Factor 1.04
1998 Impact Factor 0.938
1997 Impact Factor 0.735
1996 Impact Factor 0.84
1995 Impact Factor 0.967
1994 Impact Factor 0.959
1993 Impact Factor 0.972
1992 Impact Factor 1.034

Impact factor over time

Impact factor

Additional details

5-year impact 1.76
Cited half-life 0.00
Immediacy index 0.25
Eigenfactor 0.01
Article influence 0.49
Website Archives of Oral Biology website
Other titles Archives of oral biology
ISSN 0003-9969
OCLC 2484813
Material type Periodical, Internet resource
Document type Journal / Magazine / Newspaper, Internet Resource

Publisher details


  • Pre-print
    • Author can archive a pre-print version
  • Post-print
    • Author can archive a post-print version
  • Conditions
    • Pre-print allowed on any website or open access repository
    • Voluntary deposit by author of authors post-print allowed on authors' personal website, or institutions open scholarly website including Institutional Repository, without embargo, where there is not a policy or mandate
    • Deposit due to Funding Body, Institutional and Governmental policy or mandate only allowed where separate agreement between repository and the publisher exists.
    • Permitted deposit due to Funding Body, Institutional and Governmental policy or mandate, may be required to comply with embargo periods of 12 months to 48 months .
    • Set statement to accompany deposit
    • Published source must be acknowledged
    • Must link to journal home page or articles' DOI
    • Publisher's version/PDF cannot be used
    • Articles in some journals can be made Open Access on payment of additional charge
    • NIH Authors articles will be submitted to PubMed Central after 12 months
    • Publisher last contacted on 18/10/2013
  • Classification
    ​ green

Publications in this journal

  • [Show abstract] [Hide abstract]
    ABSTRACT: To evaluate the in vitro effectiveness of APDI with a 660nm laser combined with methylene blue (MB), toluidine blue ortho (TBO) and malachite green (MG) dyes to inactivate Staphylococcus aureus (ATCC 25923) biofilms in compact and cancellous bone specimens. Eighty specimens of compact and 80 of cancellous bone were contaminated with a standard suspension of the microorganism and incubated for 14 days at 37°C to form biofilms. After this period, the specimens were divided into groups (n=10) according to established treatment: PS-L- (control - no treatment); PSmb+L-, PStbo+L-, PSmg+L- (only MB, TBO or MG for 5min in the dark); PS-L+ (only laser irradiation for 180s); and APDImb, APDItbo and APDImg (APDI with MB, TBO or MG for 180s). The findings were statistically analyzed by ANOVA at 5% significance levels. All experimental treatments showed significant reduction of logCFU/mL S. aureus biofilms when compared with the control group for compact and cancellous bones specimens; the APDI group's treatment was more effective. The APDI carried out for the compact specimens showed better results when compared with cancellous specimens at all times of application. For the group of compact bone, APDImg showed greater reductions in CFU/mL (4.46log10). In the group of cancellous bone, the greatest reductions were found in the APDImb group (3.06log10). APDI with methylene blue, toluidine blue ortho and malachite green dyes and a 660nm laser proved to be effective in the inactivation of S. aureus biofilms formed in compact and cancellous bone. Copyright © 2015. Published by Elsevier Ltd.
    Archives of Oral Biology 05/2015; 60(5). DOI:10.1016/j.archoralbio.2015.02.010
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    ABSTRACT: The commonest bacteria, causing infection across the world is Helicobacter pylori, which colonizes the human stomach. This bacteria has also been detected in some extra-gastric ecological niches such as the oral cavity and water. However, the results of H. pylori detection in extra-gastric ecological niche are controversial. The improvement of the sensitivity and the specificity of the detection methods appear to be some of the main bottleneck issues in providing compelling evidence. The aim of this study was to detect the presence of this organism in dental plaque samples using an analytically sensitive and specific Polymerase Chain Reaction (PCR) as well as a new nucleic acid detection method termed the Loop-mediated Isothermal Amplification (LAMP). In a descriptive cross-sectional study 45 participants enrolled and dental plaque samples were collected from at least two teeth surfaces (one anterior and one posterior tooth) using a sterile periodontal curette. The DNA content was extracted from the samples and the presence of H. pylori was determined by PCR and LAMP reactions. The frequency of detection of H. pylori in the dental plaque samples were 44% (20/45), 66.67% (30/45) and 77.78% (35/45) using PCR, LAMP and positivity for both tests, respectively. The high frequency of H. pylori was detected in the dental plaque samples of the participants, which concurs with the high prevalence of this bacteria in the population. This is one of the highest reported rates around the world. The results reveal that dental plaque can be one of the main causes of re-infection and also be the cause of oral-oral transmission. Copyright © 2015 Elsevier Ltd. All rights reserved.
    Archives of Oral Biology 05/2015; 60(5). DOI:10.1016/j.archoralbio.2015.02.006
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    ABSTRACT: To examine the effect of low-level jaw clenching on temporal summation in healthy volunteers. In 18 healthy volunteers, the pain intensities evoked at the masseter muscle and the hand palm by the first and last stimuli in a train of repeated electrical stimuli (0.3 or 2.0Hz) were rated using 0-100mm visual analogue scales (VAS), in order to evaluate temporal summation before and after three types of jaw-muscle tasks: low-level jaw clenching, repetitive gum chewing and mandibular rest position. A set of concentric surface electrodes with different diameters (small and large) was used for the electrical stimulation. The temporal summation evoked by the large diameter electrode with 2.0Hz stimulation decreased significantly both on the masseter and the hand after low-level clenching (P≤0.03), but did not show any significant change after the other tasks (P>0.23). The VAS score of the first stimulation did not show any significant changes after low-level clenching (P>0.57). Experimental low-level jaw clenching can inhibit pain sensitivity, especially temporal summation. Low-level jaw clenching can modify pain sensitivity, most likely through the central nervous system. The findings suggest that potential harmful low-level jaw clenching or tooth contacting could continue despite painful symptoms, e.g., temporomandibular disorders. Copyright © 2015 Elsevier Ltd. All rights reserved.
    Archives of Oral Biology 05/2015; 60(5). DOI:10.1016/j.archoralbio.2015.02.013
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    ABSTRACT: The aim of this paper was to compare the chemical composition of human teeth with other mammal species that are likely candidates for replacing them in studies that test dental material. Dentine and enamel fragments extracted from 400 sound human, bovine, porcine and ovine - 100 teeth per species - incisors and molars were mechanically ground up to a final particle size of less than 100μm. C/N analysis, thermogravimetric analysis coupled to mass spectrometry (TG-MS), and wavelength dispersive X-ray fluorescence (WDXRF) were used to analyse the samples' composition. Elemental analysis showed more organic carbon and nitrogen in dentine than in enamel. Human enamel was the most highly mineralised, with C and N values close to hydroxyapatite. Bovine dentine and enamel were the most similar to human. TG-MS: in all species, enamel contained less carbon and organic matter than dentine. Thermal decomposition of human enamel showed great similarity to synthetic hydroxyapatite, and large differences from bovine, ovine and porcine enamel. Thermal decomposition showed the greatest similarity between human and bovine dentine. Dentine contained larger quantities of Mg, S, Sr and Zn than enamel. Enamel contained larger quantities of P, Ca, Cl, Cu, K and Ca/P ratio than dentine. Human enamel and dentine contained a higher Ca/P ratio, larger quantities of Cl and Cu and lower quantities of Mg, S, Zn than the animal species. Elemental analysis, TG-MS and WDXRF have shown that human and bovine enamel and dentine show the greatest similarity among the species analysed. Copyright © 2015 Elsevier Ltd. All rights reserved.
    Archives of Oral Biology 05/2015; 60(5). DOI:10.1016/j.archoralbio.2015.01.014
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    ABSTRACT: The aim of this study was to determine the antibacterial effect of different formulations containing Lysozyme and Lactoferrin and drug delivery system as well as poloxamer 407 with the trade name of Pluronic F-127 and/or freeze dried liposome containing DOTAP [freeze dried Liposomal DOTAP] on Streptococcus sobrinus, Streptococcus mutans and Lactobacillus acidophilus in comparison with 0.2% chlorhexidine. The antibacterial effect was assessed by determining the minimum inhibitory concentrations (MIC) for the study and control groups on Streptococcus sobrinus, Streptococcus mutans and Lactobacillus acidophilus. The amounts of biofilm formation accumulation of Mutans Streptococci for 24h on sterile hydroxyapatite discs after application of different formulations were evaluated. The different formulations studied were: (1) Sorensen's Buffer Solution, (2) a gel formulation containing only poloxamer 407, (3) Lysozyme and Lactoferrin dissolved in Sorensen's Buffer Solution, (4) poloxamer 407 combined with the third formulation, (5) Freeze dried Liposomal DOTAP dissolved in Sorensen's Buffer Solution, (6) Freeze dried Liposomal DOTAP combined with poloxamer 407 dispersed in Sorensen's Buffer Solution, (7) Freeze dried Liposomal DOTAP combined with the third formulation, and (8) Lysozyme and Lactoferrin dissolved in Sorensen's Buffer Solution, which was then incorporated into poloxamer 407 and combined with Freeze dried Liposomal DOTAP. The positive and negative control groups were 0.2% chlorhexidine gel and empty hydroxyapatite discs, respectively. Statistical evaluation was carried out with Kruskal-Wallis and Dunn's multiple comparison tests. It was observed that the first, third and fifth groups did not have any antibacterial effects on the tested bacteria. The groups that contained poloxamer 407 had nearly identical antibacterial effects on Mutans Streptococci and L. acidophilus. These formulations also inhibited biofilm formation of the bacteria (p<0.05) more effectively. In the positive control group, there was no biofilm formation. Among the formulations containing poloxamer 407, the one containing Lysozyme and Lactoferrin exhibited the highest inhibitory effect on the tested bacteria. This novel formulation can be beneficial as an antibacterial agent for the prevention of dental caries and biofilm formation. Copyright © 2015 Elsevier Ltd. All rights reserved.
    Archives of Oral Biology 05/2015; 60(5). DOI:10.1016/j.archoralbio.2015.02.004
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    ABSTRACT: IL-6 plays critical roles in bone resorption and the pathogenesis of periodontitis in both inflammation and alveolar bone loss. A negative correlation was observed between periodontitis and truncal bone mineral density (BMD) in postmenopausal women. The C allele carriers of a genetic polymorphism IL-6-572G/C have higher levels of serum IL-6 compared to G allele carriers. We investigated the possible effect of IL-6-572G/C polymorphism on the relationship between low BMD and periodontitis in postmenopausal women.
    Archives of Oral Biology 04/2015; 60(4). DOI:10.1016/j.archoralbio.2014.12.005
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    ABSTRACT: Expression of a large number of genes during differentiation of undifferentiated pulp cells into odontoblastic cells is still unknown, hence the aim of this investigation was to compare undifferentiated pulp cells (OD-21) and odontoblast-like cells (MDPC-23) through the assessment of cell stimulation and gene expression profiling.
    Archives of Oral Biology 04/2015; 60(4). DOI:10.1016/j.archoralbio.2014.09.015
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    ABSTRACT: The oral cavity is often exposed to not only diverse external pathogens but also dramatic temperature changes. In this study, we investigated the effect of thermal stress on PDL cells with a focus on the inflammatory responses and bone homeostasis.
    Archives of Oral Biology 04/2015; 60(4). DOI:10.1016/j.archoralbio.2014.12.014
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    ABSTRACT: The aim of this study was to investigate enzymatic and non-enzymatic antioxidant systems and levels of biomarker levels of oxidative damage in the saliva of patients with Down's syndrome (DS).
    Archives of Oral Biology 04/2015; 60(4). DOI:10.1016/j.archoralbio.2014.09.013
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    ABSTRACT: The present study aimed to investigate the effectiveness of platelet-rich fibrin (PRF) on bone regeneration when used alone or in combination with hydroxyapatite (HA)/beta-tricalcium phosphate (βTCP).
    Archives of Oral Biology 04/2015; 60(4). DOI:10.1016/j.archoralbio.2014.09.017
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    ABSTRACT: This narrative review of the functions of saliva was conducted in the PubMed, Embase and Web of Science databases. Additional references relevant to the topic were used, as our key words did not generate references which covered all known functions of saliva. These functions include maintaining a moist oral mucosa which is less susceptible to abrasion, and removal of micro-organisms, desquamated epithelial cells, leucocytes and food debris by swallowing. The mucins form a slimy coating on all surfaces in the mouth and act as a lubricant during such processes as mastication, formation of a food bolus, swallowing and speaking. Saliva provides the fluid in which solid tastants may dissolve and distributes tastants around the mouth to the locations of the taste buds. The hypotonic unstimulated saliva facilitates taste recognition. Salivary amylase is involved in digestion of starches. Saliva acts as a buffer to protect oral, pharyngeal and oesophageal mucosae from orally ingested acid or acid regurgitated from the stomach. Saliva protects the teeth against acid by contributing to the acquired enamel pellicle, which forms a renewable lubricant between opposing tooth surfaces, by being supersaturated with respect to tooth mineral, by containing bicarbonate as a buffer and urea and by facilitating clearance of acidic materials from the mouth. Saliva contains many antibacterial, antiviral and antifungal agents which modulate the oral microbial flora in different ways. Saliva also facilitates the healing of oral wounds. Clearly, saliva has many functions which are needed for proper protection and functioning of the human body. Copyright © 2015 Elsevier Ltd. All rights reserved.
    Archives of Oral Biology 03/2015; 60(6). DOI:10.1016/j.archoralbio.2015.03.004
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    ABSTRACT: In the present study, we explored the effect of the ethanol extract of Osmanthus fragrans (EOF) on the growth and collagenase activity of Porphyromonas gingivalis (P. gingivalis). We also investigated the capacity of EOF to attenuate P. ginggivalis lipopolysaccharide (LPS)-induced inflammatory responses and the possible signaling pathway.
    Archives of Oral Biology 03/2015; DOI:10.1016/j.archoralbio.2015.02.026
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    ABSTRACT: The purposes of this investigation were to study the prevalence of Candida albicans and non-albicans Candida (NAC) species from oral candidiasis patients and evaluate the cell surface hydrophobicity (CSH) and biofilm forming capacity of the clinical isolates Candida species from oral cavity. This study identified a total of 250 Candida strains isolated from 207 oral candidiasis patients with PCR-RFLP technique. CSH value, total biomass of biofilm and biofilm forming ability of 117 oral Candida isolates were evaluated. C. albicans (61.6%) was still the predominant species in oral candidiasis patients with and without denture wearer, respectively, followed by C. glabrata (15.2%), C. tropicalis (10.4%), C. parapsilosis (3.2%), C. kefyr (3.6%), C. dubliniensis (2%), C. lusitaniae (2%), C. krusei (1.6%), and C. guilliermondii (0.4%). The proportion of mixed colonization with more than one Candida species was 18% from total cases. The relative CSH value and biofilm biomass of NAC species were greater than C. albicans (p<0.001). Ninety-two percent of oral isolates NAC species had biofilm forming ability, whereas 78% of C. albicans were biofilm formers. Furthermore, the significant difference of relative CSH values between biofilm formers and non-biofilm formers was observed in the NAC species (p<0.005), whereas the difference was not statistically significant in C. albicans. The frequency of the NAC species colonization in oral cavity was gradually increasing. The possible contributing factors might be high cell surface hydrophobicity and biofilm forming ability. The relative CSH value could be a putative factor for determining biofilm formation ability of the non-albicans Candida species. Copyright © 2015 Elsevier Ltd. All rights reserved.
    Archives of Oral Biology 03/2015; 17(6). DOI:10.1016/j.archoralbio.2015.03.002
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    ABSTRACT: Salivary α-amylase, a major protein in saliva, has been described as a marker for sympathetic nervous system activity, hence for metabolic energy balance. In this context, its expression in overweight and obesity is of interest. Rats fed with a diet enriched with sunflower oil differentially gained weight yielding two subgroups according to their susceptibility (OP) or resistance (OR) to obesity. Elevated plasmatic levels of leptin in the OP subgroup and altered plasmatic lipid profiles (lower triglycerides and higher total cholesterol/HDL ratio compared to controls) in OR subgroup were observed. Animals from OP subgroup presented higher α-amylase expression and activity even prior to the dietary treatment, suggesting that this salivary protein may constitute a putative indicator of susceptibility for fat tissue accumulation. After 18 weeks of high-fat diet consumption, salivary α-amylase levels did not significantly changed in OP subgroup, but increased 3-fold in OR subgroup. The raise of α -amylase for the latter might represent an adaptation to lower starch intake. These results suggest that salivary α-amylase secretion might be useful to predict susceptibility for weight gain induced by high-fat diet consumption.
    Archives of Oral Biology 02/2015;
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    ABSTRACT: Aim The aim of this study was to investigate the smoking habit influence on DNA methylation status in the promoters of the cancer related-genes MLH1, hTERT and TP53 in oral epithelial cells of healthy subjects. Material and Methods DNA Methylation analysis was performed using Methylation-Sensitive Restriction Enzymes (MSRE) in oral epithelial cells from non-smokers, smokers and ex-smokers. Results The investigated CpG dinucleotides located at HhaI and HpaII sites in the MLH1 gene promoter were observed to be fully methylated in the majority of DNA samples from the smoker group and statistical differences were found between non-smokers and smokers and between smokers and ex-smokers (p < 0.05). The same was observed in the hTERT gene promoter at HhaI sites (p < 0.05) and for HpaII sites the unmethylated condition was more frequent in smokers in comparison to non-smokers (p < 0.05). For TP53, no differences were found among groups (p > 0.05), with the fully methylated condition found to be a common event in healthy oral epithelial cells. Conclusion We conclude that smoking may induce changes in DNA methylation status in cancer-related genes of oral epithelial cells and that the cessation of smoking is capable of reversing this process. Based on our data, we suggest that DNA methylation status of the hTERT and MLH1 gene promoters are promising markers for screening a set of smoking-related alterations in oral cells.
    Archives of Oral Biology 02/2015; 60(6). DOI:10.1016/j.archoralbio.2015.02.022