The Antiseptic (Antiseptic)
Current impact factor: 0.00
Impact Factor Rankings
|Document type||Journal / Magazine / Newspaper|
Publications in this journal
- The Antiseptic 03/2012; 109(3):142-144.
- The Antiseptic 01/2012; 109(1):30-32.
- The Antiseptic 01/2012; 109(1):27-29.
- The Antiseptic 01/2012; 109(1):23.
- The Antiseptic 12/2011; 108(12):607-610.
- The Antiseptic 12/2011; 108(2):595-597.
- The Antiseptic 07/2011; 108(7):326-328.
- The Antiseptic 06/2011; 108(6):285-287.
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ABSTRACT: Acne Vulgaris is the most common dermatological disorder and Propionibacterium acnes is the commonest causative organism in pathogenesis of acne inflammation. The Propionibacterium acnes release neutrophil chemotactic factors, which attracts polymorph nuclear leukocytes at the site of infection. A polymorph nuclear leukocyte induces the reactive oxygen species to create an oxidative stress, which is responsible for acne inflammation. Conventional medical treatment has its own side effects besides the high cost. Ethno botanical search reveals use of many traditional herbs in treatment of acne, which are usually free from side effects, are economical and also accessible to humans. The present in-vitro study was conducted to evaluate the antibacterial activity of Clarina cream and compare with Tetracycline against Propionibacterium acnes by agar well diffusion method using Reinforced clostridial agar media (RCA) Hi-media. The antibacterial activity of Clarina cream at concentrations of 50 and 100 mg was compared with Standard antibiotic Tetracycline (0.5µg). The results showed the zone of inhibition with Clarina cream at 50mg against Propionibacterium acne was 12.00 ± 0.00 mm when the concentration of Clarina Cream increased to 100 mg showed a further inhibition of 15.25 ± 0.25 mm. In comparison with that of standard antibiotic Tetracycline at 0.5µg concentration using agar well diffusion method showed 19.75 ± 0.25 mm inhibition. This comparative in-vitro evaluation of Clarina cream clearly shows that Clarina cream inhibits the growth of the acne causing organism Propionibacterium acnes, which is comparable to the standard antibiotic Tetracycline which is the most effective and commonly used treatment for acne. The efficacy of Clarina cream can be attributed to the synergistic effects of its potent herbs. Key words: Clarina cream, Propionibacterium acnes, Antibacterial activityThe Antiseptic 05/2011; 108.
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