Acta gastro-enterologica Belgica Journal Impact Factor & Information

Publisher: Societé Royale Belge de Gastro-Entérologie

Journal description

Current impact factor: 0.58

Impact Factor Rankings

2015 Impact Factor Available summer 2015
2012 Impact Factor 0.581
2011 Impact Factor 0.638
2010 Impact Factor 0.648
2009 Impact Factor 1.01
2008 Impact Factor 0.832
2007 Impact Factor 1.096
2006 Impact Factor 0.736
2005 Impact Factor 0.826
2004 Impact Factor 0.713
2003 Impact Factor 0.67
2002 Impact Factor 0.636
2001 Impact Factor 0.444
2000 Impact Factor 0.605
1999 Impact Factor 0.602
1996 Impact Factor 0.182
1995 Impact Factor 0.857
1994 Impact Factor 0.87
1993 Impact Factor 0.13
1992 Impact Factor 0.059

Impact factor over time

Impact factor
Year

Additional details

5-year impact 0.61
Cited half-life 7.30
Immediacy index 0.08
Eigenfactor 0.00
Article influence 0.17
Website Acta Gastro Enterologica Belgica website
Other titles Acta gastro-enterologica belgica
ISSN 0001-5644
OCLC 1460883
Material type Periodical
Document type Journal / Magazine / Newspaper

Publications in this journal

  • [Show abstract] [Hide abstract]
    ABSTRACT: Leucocytoclastic vasculitis (LCV) is commonly presented as a skin disease by affecting the small vessels of targeted area. Containing loops of vessels with end- capillaries makes the small intestine villus potantially target area of LcV, when obstructed with immune complexes. © Acta Gastro-Enterologica Belgica.
    Acta gastro-enterologica Belgica 04/2015; 78(2):250-251.
  • Acta gastro-enterologica Belgica 04/2015; 78(2):253-254.
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    ABSTRACT: Epidemiological and investigational studies have proved that vitamin D is important in autoimmune processes and has anticancerogenic properties. But the interplay between serum vitamin D and parathyroid hormone (PTH) in colorectal polyps has been less clearly put forward. We evaluated serum vitamin D, PTH levels in Turkish people and tried to stratify colorectal polyps according to risk factors. Patients undergoing colonoscopy between January 2012 and March 2012 were considered to study serum vitamin D levels during winter. Study population comprised of 98 colorectal polyp and 197 normal colonoscopy patients. Serum vitamin D levels were not different between the groups (mean vitamin D level in polyp group 14.3 ± 11.1 vs. 12.7 ± 6.74 the normal group, p = 0.12). Likewise serum PTH levels were not different between the groups Patients with polyps were further classified as high and low risk polyps. When discriminant function analysis was conducted, the effects of vitamin D or PTH levels were not again significant. During the study period 16 colorectal carcinoma cases were detected. Serum vitamin D or PTH levels were not significantly different between colorectal cancer or overall study group patients. Finally serum vitamin D levels were stratified into quartiles. Likewise there was not any significant difference between the groups. The present study suggests that serum vitamin D and PTH levels were not different between colorectal polyp and control groups. And serum vitamin D levels were significantly low in both groups suggesting a significant vitamin D deficient state in Turkish patients. © Acta Gastro-Enterologica Belgica.
    Acta gastro-enterologica Belgica 04/2015; 78(2):206-211.
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    ABSTRACT: Splenic abscess are rare conditions. Since morbidity and mortality rates are high, immediate diagnosis should be required. Here we presented an ulcerative colitis patients who develops splenic abscess under anti tumor necrosis factor treatment. © Acta Gastro-Enterologica Belgica.
    Acta gastro-enterologica Belgica 04/2015; 78(2):252.
  • Acta gastro-enterologica Belgica 04/2015; 78(2):259.
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    ABSTRACT: Hepatotoxic complications of long-term oral amiodarone therapy have been well described ; however, liver injury secondary to parenteral infusion of amiodarone is uncommon, potentially fatal, and poorly understood. The hepatotoxicity is thought to result from the diluent polysorbate 80 and not the amiodarone its self. Theories suggest an allergic or immunologic response leading to alterations in the hepatocellular membrane while some propose that ischemia, not a drug reaction, is truly to blame. Both the PubMed and Embase databases were searched for cases of acute hepatitis implicating intravenous amiodarone with a total of 25 cases from 1986 to 2012 identified. Each case was then carefully evaluated to determine the connection between parenteral amiodarone and acute hepatotoxicity while assessing for evidence of potential ischemia. Of the 25 published cases of amiodarone induced acute hepatotoxicity available for review, only 10 provide evidence to conclusively implicate parenteral amiodarone as the etiology. We add the eleventh reported case of parenteral amiodarone induced acute severe hepatitis to the literature and report the most comprehensive review of this topic to date. There is sufficient evidence to support amiodarone induced acute hepatotoxicity as a unique entity separate from ischemic hepatitis. If suspected, parenteral amiodarone should be discontinued and held indefinitely. © Acta Gastro-Enterologica Belgica.
    Acta gastro-enterologica Belgica 04/2015; 78(2):233-239.
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    ABSTRACT: We showed in this study that rifampicin therapy is more effective than plasmapheresis and steroid treatment in diseases associated with severe hyperbilirubinemia. In our opinion, rifampicin treatment may suitable especially for patients with persistent hyperbilirubinemia, and it would be appropriate to use rifampicin as a challenge therapy to patients with severe hyperbilirubinemia, but liver function tests in these patients must be monitored closely. © Acta Gastro-Enterologica Belgica.
    Acta gastro-enterologica Belgica 04/2015; 78(2):256-258.
  • Acta gastro-enterologica Belgica 04/2015; 78(2):255.
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    ABSTRACT: Two patients were admitted to emergency room with complaint of abdominal pain with abrupt onset and retroperitoneal free air was detected in pararenal area on CT. In this paper, characteristic CT findings of patients diagnosed with duodenal perforation are presented under the light of literature data. © Acta Gastro-Enterologica Belgica.
    Acta gastro-enterologica Belgica 04/2015; 78(2):248-249.
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    ABSTRACT: Upper esophageal strictures occur in approximately 3-4% of patients who receive radiotherapy for head and neck cancers. The standart initial treatment is dilation by using bougie or through-the-scope balloon dilators. Endoscopic treatment requires the passage of a guidewire through the stricture which cannot be accomplished in some of the patients with complex strictures. Retrograde dilation of esophageal strictures through a mature percutaneous gastrostomy tract have been reported in a limited number of cases and small case series up to date and can be considered as a rescue treatment before considering surgery in such patients. Herein we report retrograde dilatation of a radiation-induced complex esophageal stricture through the percutaneous gastrostomy tract in a patient with operated larynx cancer. © Acta Gastro-Enterologica Belgica.
    Acta gastro-enterologica Belgica 04/2015; 78(2):246-247.
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    ABSTRACT: Over the past decades the identification of several molecules that are expressed specifically in the lymphatic endothelial cells has resulted in marked advances in the field of lymphangiogenesis. We aimed to measure LVD in colorectal cancer patients and to compare it with microvascular density (MVD) - a marker of angiogenesis - and patients' clinicopathological parameters and survival, as the measurement of lymphatic vessel density (LVD) has been documented in various tumor types, including colorectal cancer. Fifty one patients who had undergone surgical resection for stage I-III colorectal cancer entered this study. LVD and MVD were determined immunohistochemically with the use of D2-40 and CD34 antibody respectively. The evaluation of LVD was performed by both visual and computer-aided image analysis. The majority of lymphatic vessels were located in the peritumoral areas rather than within the tumor. The results obtained from the image analyzer correlated significantly with the data obtained using visual counting with light microscopy. Both visual and image analysis LVD failed to correlate with patients' age and gender and tumor location, stage, grade, MVD count and survival. The biologic role of the lymphatic vasculature in tumor progression remains controversial. The present study failed to associate LVD with outcome markers and prognosis and further studies would be required to verify our results. © Acta Gastro-Enterologica Belgica.
    Acta gastro-enterologica Belgica 04/2015; 78(2):223-227.
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    ABSTRACT: Chronic recurrent multifocal osteomyelitis (CRMO) is an autoinflammatory bone disease of unknown etiology, most commonly affecting the metaphysis of long bones, especially the tibia, femur and clavicle. The clinical spectrum varies from self-limited uni-or multi-focal lesions to chronic recurrent courses. Diagnosis is based on clinical, radiologic and pathological findings, is probably underdiagnosed due to poor recognition of the disease. A dysregulated innate immunity causes immune cell infiltration of the bones with subsequent osteoclast activation leading to sterile bone lesions. The molecular pathophyiology is still incompletely understood but association with other auto-inflammatory diseases such as inflammatory bowel disease (IBD), psoriasis, Wegener's disease, arthritis and synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome is interesting. CRMO can precede the symptoms of the associated disease by several years. The bone remodeling caused by CRMO can cause permanent disability. We report the case of a 10-year-old boy with CRMO in association with Crohn's disease. © Acta Gastro-Enterologica Belgica.
    Acta gastro-enterologica Belgica 04/2015; 78(2):240-243.
  • Acta gastro-enterologica Belgica 04/2015; 78(2):244-245.
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    ABSTRACT: Oxidative stress is increased and anti-oxidant defense mechanisms are impaired in patients with hepatosteatosis. The aim of the present study was to evaluate the serum levels of several oxidant and anti-oxidant markers in patients with nonalcoholic fatty liver disease (NAFLD). Thirty-four patients with NAFLD, and 19 healthy controls were included. In this study, we measured serum nitrate and advanced oxidation protein product (AOPP) as the oxidizing products and nitrite as the anti-oxidizing marker. Nitrate and nitrite levels were measured using a calorimetric method, and levels of serum AOPP were measured by a spectrophotometric method using a commercial ELISA kit. Serum nitrate and AOPP levels were significantly higher in the NAFLD group compared to the control group. Serum nitrite and N-N levels were similar between the two groups. Serum nitrate and N-N levels were found to be significantly higher in patients with elevated ALT levels compared to patients with normal ALT levels. Serum nitrite and AOPP levels were comparable between these groups. Mean platelet volume (MPV) was significantly lower in the NAFLD group compared to the control group. Serum levels of oxidizing agents including nitrate and AOPP increase in patients with NAFLD. In contrast, serum nitrite, an antioxidant agent, does not adequately increase to compensate for the oxidizing effects in these patients. © Acta Gastro-Enterologica Belgica.
    Acta gastro-enterologica Belgica 04/2015; 78(2):201-205.
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    ABSTRACT: The combination of Pegylated (PEG)interferon alpha-2b and ribavirin is considered to be the standard treatment for naïve chronic hepatitis C patients. Study aims are to evaluate the differences between standard interferon and PEG-interferon by conducting a multi-centre, controlled randomized trial comparing 3 groups. Group A : daily interferon alfa-2b at a dose of 4 MIU + ribavirin, Group B : PEG-interferon alfa-2b at a dose of 100 mcg/week + ribavirin; Group C: interferon alfa-2b at a dose of 3 MIU TIW + ribavirin Multicentrer, open label study including naïve chronic Hepatitis C Virus patients randomised in three groups with a ratio of 2:2:1. Group A: daily interferon alpha-2b (4 MIU s.c. for patients > 65 kg or 0.06 MIU/kg < 65 kg) and ribavirin, group B: PEG-interferon alpha-2b (100 microg s.c. weekly for patients > 65 kg or 1.5 microg/kg weekly for patients < 65 kg) and ribavirin and group C (reference arm) : interferon alpha-2b (3MIU s.c. TWI) and ribavirin. The duration of the treatment was 48 weeks for all 3 groups, with a 6 month follow-up period. 336 patients were enrolled in the study and included in the intention-to-treat analysis; 78 never started treatment (35 in group A, 28 in group B and 15 in group C): 101 in group A, 98 in group B and 59 in group C. Demographic data, PCR results and reasons for early withdrawal have been statistically analysed. At baseline, the 3 groups did not show any statistical difference regarding age, gender, race, genotypes and METAVIR score. At week 24 on treatment, HCV ribonucleic acid RNA was undetectable in 87% in group A, in 79% in group B and in 69% in group C. At the end of treatment, 73% 74% and 58% respectively, had a negative PCR result. At week 24 of follow-up, these results were 71%, 64% and 48%, respectively. When comparing the efficacy of the daily interferon (+ ribavirin) and the PEG-interferon (+ ribavirin) regimen, no statistical difference was found (p = 0.32). In group A, 38% of drop-outs were due to adverse events compared to 37% in group B and 58% in group C. No statistical differences were observed regarding safety. Daily weight based interferon alpha-2b dosing and PEG interferon alpha-2b weighed based dosing once weekly both in combination with Ribavirin offer the same efficacy and safety rates.
    Acta gastro-enterologica Belgica 03/2015; 71(3):293-7.
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    ABSTRACT: Background Due to the growing use of immunomodulator therapy in inflammatory bowel diseases (IBD), physicians increasingly encounter opportunistic infections in caring for patients with IBD. To the best of our knowledge, there is only one case report of a systemic Bartonella henselae infection in association with Crohn’s disease, which occured during immunosuppressive treatment with infliximab. Aim We describe a case of systemic bartonellosis in a Crohn's disease patient treated by azathioprine. Case report A 61-year-old man had been treated for ileal Crohn's disease since 2004 and had received azathioprine (2.5 mg/kg/day) for 2 years. In January 2014, he was hospitalized for high fever, night sweats and weight loss. Endoscopy disclosed active duodenal Crohn’s disease. The diagnostic work-up revealed serum inflammation, mild cytolytic and cholestatic hepatitis, “biologic” pancreatitis (rapidly resolving) and a suspicion of cholangitis on endoscopic ultrasound (EUS). Common infections were excluded and no improvement was seen with antibiotic treatment (piperacillin/tazobactam). An infectious mononucleosis was suspected since anti-EBV IgM and IgG antibodies were positive, together with splenomegaly on imaging. However, Epstein-Barr Virus (EBV) Polymerase Chain Reaction (PCR) analysis was negative, indicating a false-positive test result. One month later, despite the initial clinical improvement, a necrotic submaxillary adenopathy was diagnosed, suggesting a lymphoma. Cervical node biopsy showed nonspecific subacute inflammation indicating an infectious process. Bone marrow biopsy was negative for lymphoma. Whole body 18F-FDG positron emission tomography/computed tomography (PET/CT) displayed hypermetabolic lesions in both infra- and supra-diaphragmatic lymph nodes, in the spleen and diffusely in the skeleton. Magnetic resonance imaging of the spleen revealed multiple septic lesions. The medical work-up showed doubtful Bartonella henselae serology. EUS-guided fine needle aspiration biopsies of mediastinal lymph nodes were performed and disclosed nonspecific acute adenitis with non-necrotizing granulomas. Systemic bartonellosis was confirmed by PCR analysis of the lymph node tissue. Retrospectively, the patient reported a cat scratch on his nose a few days before the beginning of his symptoms. Serologic cross-reactivity could explain the prior false-positive EBV testing. The symptoms of the patient resolved following discontinuation of azathioprine together with a five-day azithromycin regime. Lesions on 18F-FDG PET/CT imaging disappeared completely, except splenomegaly and the thickening of the common bile duct on abdominal ultrasound. At follow-up 6 months later, the patient was completely asymptomatic. Discussion Bartonella henselae is the agent of cat scratch disease in immunocompetent hosts. In contrast, immunocompromised patients (transplant recipients, patients with acquired immunodeficiency syndrome, cancer patients under chemotherapy, patients treated with tumor necrosis factor-alpha [TNFα] antagonists…) are at risk of developing systemic bartonellosis, with extranodal manifestations including neurologic, hepatic and/or bone involvement. Conclusions Systemic Bartonella henselae infection is a rare complication of immunosuppression in Crohn’s disease patients, even without TNFα blockers, and should be kept in mind in the differential diagnosis of fever of unknown origin and polyadenopathy in this population. Source: http://www.bwge.be/program/ (see Case Reports)
    Acta gastro-enterologica Belgica 03/2015; 78(1):112.
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    ABSTRACT: Until now, "eosinophilic hepatitis" has not been recognized as a separate disease entity. We report a case of a middle-aged women with an acute febrile, severe cholestatic hepatitis accompanied with rash and quincke oedema, and an elevated serum IgE level. Liver biopsy showed lymphocytic inflammation with a remarkably high number of eosinophils. She responded rapidly to methylprednisolone treatment, which could be quickly tapered off and stopped without relapse. The term 'idiopathic acute eosinophilic hepatitis' seems to be the best fitting diagnostic term. Copyright© Acta Gastro-Enterologica Belgica.
    Acta gastro-enterologica Belgica 01/2015; 78(1):65-8.