Research job details

Bench Scientist/Scientific Associate II Job - Chemistry/Analytical Chemistry/Pharmaceutics - Switzerland Novartis Pharma AG, Basel

Position:
Researcher
Employer:
Novartis Switzerland Pharma AG
Location:
4002 Basel, Switzerland
Application deadline:
Jul 5, 2010

Job description

Group

The Biotransformation group of DMPK is responsible for constructing metabolic pathways and structure elucidation of metabolites formed in-vitro or in-vivo for Novartis development compounds after different routes of administration in blood, excreta, and tissues. In many cases radiolabeled compounds are used. We have small highly motivated lab teams that collaborate closely alongside strong interactions with other DMPK groups in DMPK. We have the latest analytical instrumentation including UPLC-MS.

Responsibilities

As a Scientific Associate / bench scientist, your work will include

  • Develop analytical assays, HPLC-UV with online/off line radioactivity detection for metabolite profiling
  • Develop analytical assays, HPLC-MS/MS for the structure elucidation of metabolites
  • Support pre-clinical/clinical metabolism ADME studies
  • Good documentation of experiments
  • Assure and maintain quality standards used within the laboratories
  • Maintain laboratory infrastructure

Minimum Requirements

  • MSc in Chemistry, Analytical Chemistry, Pharmaceutics
    or
  • other scientific degree and good experience doing this work
  • Strong post-degree relevant experience within a quantitative/qualitative analytical laboratory with metabolite profiling and metabolite identification using techniques such as LC-MS/MS
  • Knowledge of HPLC and mass spectrometry: experience with basic instrument maintenance and troubleshooting
  • Ability to work independently and collaboratively, multitask different projects, take initiative, identify and execute priorities
  • Fluent verbal and written English. German or French useful

We want to discover, develop and successfully market innovative products to prevent and cure diseases, to ease suffering and to enhance the quality of life.

We also want to provide a shareholder return that reflects outstanding performance and to adequately reward those who invest ideas and work in our company.


Novartis was created in 1996 through the merger of Ciba-Geigy and Sandoz, two companies with a rich and diverse corporate history. Throughout the years, Novartis and its predecessor companies have discovered and developed many innovative products for patients and consumers worldwide. 

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Tags

Analytical chemistry

Biotransformation

Dmpk

Hormones

Metabolic Pathways

Pharmacology

Pharmaconomy

Pharmacy

Structure Elucidation

Translational Sciences

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