Division of Structural Biology (STRUBI)

Publications (169)

• Article: Accurate ordering of eigenvectors and singular vectors without eigenvalues and singular values

  K.V. Fernando
  Linear Algebra and its Applications.
• Article: Cloning, expression, purification, and crystallisation of HIV-2 reverse transcriptase

  Louise E Bird, Philip P Chamberlain, Guillaume B.E Stewart-Jones, Jingshan Ren, David I Stuart, David K Stammers
  Protein Expression and Purification.
• Article: Killer cell immunoglobulin receptors and T cell receptors bind peptide-major histocompatibility complex class I with distinct thermodynamic and kinetic properties.

  K Maenaka, T Juji, T Nakayama, J R Wyer, G F Gao, T Maenaka, N R Zaccai, A Kikuchi, T Yabe, K Tokunaga, K Tadokoro, D I Stuart, E Y Jones, P A van der Merwe
  Journal of Biological Chemistry 11/1999; 274(40):28329-34. · 4.77 Impact Factor
• Article: MHC superfamily structure and the immune system.

  K Maenaka, E Y Jones
  Current Opinion in Structural Biology 12/1999; 9(6):745-53. · 9.42 Impact Factor
• Article: Phenylethylthiazolylthiourea (PETT) non-nucleoside inhibitors of HIV-1 and HIV-2 reverse transcriptases. Structural and biochemical analyses.

  J Ren, J Diprose, J Warren, R M Esnouf, L E Bird, S Ikemizu, M Slater, J Milton, J Balzarini, D I Stuart, D K Stammers
  Journal of Biological Chemistry 03/2000; 275(8):5633-9. · 4.77 Impact Factor
• Article: Binding of the second generation non-nucleoside inhibitor S-1153 to HIV-1 reverse transcriptase involves extensive main chain hydrogen bonding.

  J Ren, C Nichols, L E Bird, T Fujiwara, H Sugimoto, D I Stuart, D K Stammers
  Journal of Biological Chemistry 06/2000; 275(19):14316-20. · 4.77 Impact Factor
• Article: Nonstandard peptide binding revealed by crystal structures of HLA-B*5101 complexed with HIV immunodominant epitopes.

  K Maenaka, T Maenaka, H Tomiyama, M Takiguchi, D I Stuart, E Y Jones
  The Journal of Immunology 10/2000; 165(6):3260-7. · 5.79 Impact Factor
• Article: Structural basis of pore formation by cholesterol-binding toxins.

  R J Gilbert, J L Jiménez, S Chen, P W Andrew, H R Saibil
  International Journal of Medical Microbiology 11/2000; 290(4-5):389-94. · 4.17 Impact Factor
• Article: Structural basis for the resilience of efavirenz (DMP-266) to drug resistance mutations in HIV-1 reverse transcriptase.

  J Ren, J Milton, K L Weaver, S A Short, D I Stuart, D K Stammers
  Structure 11/2000; 8(10):1089-94. · 6.35 Impact Factor
• Article: Identification of many crystal forms of Aspergillus nidulans dehydroquinate synthase.

  C E Nichols, J Ren, H Lamb, F Haldane, A R Hawkins, D K Stammers
  Acta Crystallographica Section D Biological Crystallography 03/2001; 57(Pt 2):306-9. · 12.62 Impact Factor
• Article: Conserved organization of the ILT/LIR gene family within the polymorphic human leukocyte receptor complex.

  N T Young, F Canavez, M Uhrberg, B P Shum, P Parham
  Immunogenetics 04/2001; 53(4):270-8. · 2.93 Impact Factor
• Article: Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors.

  J Ren, C Nichols, L Bird, P Chamberlain, K Weaver, S Short, D I Stuart, D K Stammers
  Journal of Molecular Biology 10/2001; 312(4):795-805. · 4.00 Impact Factor
• Source

  Available from: Simon Cocklin

  Article: Expression, purification and crystallization of Aspergillus nidulans NmrA, a negative regulatory protein involved in nitrogen-metabolite repression.

  C E Nichols, S Cocklin, A Dodds, J Ren, H Lamb, A R Hawkins, D K Stammers
  Acta Crystallographica Section D Biological Crystallography 12/2001; 57(Pt 11):1722-5. · 12.62 Impact Factor
• Source

  Available from: Simon Cocklin

  Article: The structure of the negative transcriptional regulator NmrA reveals a structural superfamily which includes the short-chain dehydrogenase/reductases.

  D K Stammers, J Ren, K Leslie, C E Nichols, H K Lamb, S Cocklin, A Dodds, A R Hawkins
  The EMBO Journal 01/2002; 20(23):6619-26. · 9.20 Impact Factor
• Article: Structure of equine infectious anemia virus matrix protein.

  Hideki Hatanaka, Oleg Iourin, Zihe Rao, Elizabeth Fry, Alan Kingsman, David I Stuart
  Journal of Virology 03/2002; 76(4):1876-83. · 5.40 Impact Factor
• Article: Structure of a functional IGF2R fragment determined from the anomalous scattering of sulfur.

  James Brown, Robert M Esnouf, Margaret A Jones, Jane Linnell, Karl Harlos, A Bassim Hassan, E Yvonne Jones
  The EMBO Journal 04/2002; 21(5):1054-62. · 9.20 Impact Factor
• Article: Pore-forming toxins.

  R J C Gilbert
  Cellular and Molecular Life Sciences CMLS 06/2002; 59(5):832-44. · 6.57 Impact Factor
• Article: Crystal structures of Zidovudine- or Lamivudine-resistant human immunodeficiency virus type 1 reverse transcriptases containing mutations at codons 41, 184, and 215.

  P P Chamberlain, J Ren, C E Nichols, L Douglas, J Lennerstrand, B A Larder, D I Stuart, D K Stammers
  Journal of Virology 11/2002; 76(19):10015-9. · 5.40 Impact Factor
• Source

  Available from: pnas.org

  Article: Structure of HIV-2 reverse transcriptase at 2.35-A resolution and the mechanism of resistance to non-nucleoside inhibitors.

  J Ren, L E Bird, P P Chamberlain, G B Stewart-Jones, D I Stuart, D K Stammers
  Proceedings of the National Academy of Sciences 11/2002; 99(22):14410-5. · 9.68 Impact Factor
• Article: Atomic resolution structure of Moloney murine leukemia virus matrix protein and its relationship to other retroviral matrix proteins.

  Nico Riffel, Karl Harlos, Oleg Iourin, Zihe Rao, Alan Kingsman, David Stuart, Elizabeth Fry
  Structure 01/2003; 10(12):1627-36. · 6.35 Impact Factor
• Article: Crystal structure of SANOS, a bacterial nitric oxide synthase oxygenase protein from Staphylococcus aureus.

  Louise E Bird, Jingshan Ren, Jiancheng Zhang, Neale Foxwell, Alastair R Hawkins, Ian G Charles, David K Stammers
  Structure 01/2003; 10(12):1687-96. · 6.35 Impact Factor
• Article: Depositing electron microscopy maps.

  Stephen D Fuller
  Structure 02/2003; 11(1):11-2. · 6.35 Impact Factor
• Article: Cloning, expression, purification, and crystallisation of HIV-2 reverse transcriptase.

  Louise E Bird, Philip P Chamberlain, Guillaume B E Stewart-Jones, Jingshan Ren, David I Stuart, David K Stammers
  Protein Expression and Purification 02/2003; 27(1):12-8. · 1.59 Impact Factor
• Article: Ligand-induced conformational changes and a mechanism for domain closure in Aspergillus nidulans dehydroquinate synthase.

  C E Nichols, J Ren, H K Lamb, A R Hawkins, D K Stammers
  Journal of Molecular Biology 04/2003; 327(1):129-44. · 4.00 Impact Factor
• Article: Do lipid rafts mediate virus assembly and pseudotyping?

  John A G Briggs, Thomas Wilk, Stephen D Fuller
  Journal of General Virology 05/2003; 84(Pt 4):757-68. · 3.36 Impact Factor
• Source

  Available from: ncbi.nlm.nih.gov

  Article: Structural organization of authentic, mature HIV-1 virions and cores.

  John A G Briggs, Thomas Wilk, Reinhold Welker, Hans-Georg Kräusslich, Stephen D Fuller
  The EMBO Journal 05/2003; 22(7):1707-15. · 9.20 Impact Factor
• Article: Crystal structure of varicella zoster virus thymidine kinase.

  Louise E Bird, Jingshan Ren, Alan Wright, Kris D Leslie, Bart Degrève, Jan Balzarini, David K Stammers
  Journal of Biological Chemistry 08/2003; 278(27):24680-7. · 4.77 Impact Factor
• Article: The tailless icosahedral membrane virus PRD1 localizes the proteins involved in genome packaging and injection at a unique vertex.

  Brent Gowen, Jaana K H Bamford, Dennis H Bamford, Stephen D Fuller
  Journal of Virology 08/2003; 77(14):7863-71. · 5.40 Impact Factor
• Source

  Available from: oxfordjournals.org

  Article: Characterizing proteolytic cleavage site activity using bio-basis function neural networks.

  Rebecca Thomson, T Charles Hodgman, Zheng Rong Yang, Austin K Doyle
  Bioinformatics 10/2003; 19(14):1741-7. · 5.47 Impact Factor
• Article: The ligand-binding face of the semaphorins revealed by the high-resolution crystal structure of SEMA4D.

  Christopher A Love, Karl Harlos, Nasim Mavaddat, Simon J Davis, David I Stuart, E Yvonne Jones, Robert M Esnouf
  Natural Structural Biology 11/2003; 10(10):843-8.
• Article: Order and disorder in crystals of hexameric NTPases from dsRNA bacteriophages.

  Erika J Mancini, Jonathan M Grimes, Robyn Malby, Geoffrey C Sutton, Denis E Kainov, Jarmo T Juuti, Eugene V Makeyev, Roman Tuma, Dennis H Bamford, David I Stuart
  Acta Crystallographica Section D Biological Crystallography 01/2004; 59(Pt 12):2337-41. · 12.62 Impact Factor
• Article: Structure of the snake-venom toxin convulxin.

  Thil Batuwangala, Mireille Leduc, Jonathan M Gibbins, Cassian Bon, E Yvonne Jones
  Acta Crystallographica Section D Biological Crystallography 02/2004; 60(Pt 1):46-53. · 12.62 Impact Factor
• Article: Crystal structures of HIV-1 reverse transcriptases mutated at codons 100, 106 and 108 and mechanisms of resistance to non-nucleoside inhibitors.

  J Ren, C E Nichols, P P Chamberlain, K L Weaver, S A Short, D K Stammers
  Journal of Molecular Biology 02/2004; 336(3):569-78. · 4.00 Impact Factor
• Article: The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase.

  Paula S Salgado, Eugene V Makeyev, Sarah J Butcher, Dennis H Bamford, David I Stuart, Jonathan M Grimes
  Structure 03/2004; 12(2):307-16. · 6.35 Impact Factor
• Article: The nsp9 replicase protein of SARS-coronavirus, structure and functional insights.

  Geoff Sutton, Elizabeth Fry, Lester Carter, Sarah Sainsbury, Tom Walter, Joanne Nettleship, Nick Berrow, Ray Owens, Robert Gilbert, Andrew Davidson, Stuart Siddell, Leo L M Poon, Jonathan Diprose, David Alderton, Martin Walsh, Jonathan M Grimes, David I Stuart
  Structure 03/2004; 12(2):341-53. · 6.35 Impact Factor
• Source

  Available from: ncbi.nlm.nih.gov

  Article: Crystal structure of HLA-DQ0602 that protects against type 1 diabetes and confers strong susceptibility to narcolepsy.

  Christian Siebold, Bjarke E Hansen, Jessica R Wyer, Karl Harlos, Robert E Esnouf, Arne Svejgaard, John I Bell, Jack L Strominger, E Yvonne Jones, Lars Fugger
  Proceedings of the National Academy of Sciences 03/2004; 101(7):1999-2004. · 9.68 Impact Factor
• Article: Production, crystallization and preliminary X-ray crystallographic studies of the bacteriophage phi 12 packaging motor.

  Erika J Mancini, Denis E Kainov, Hui Wei, Paul Gottlieb, Roman Tuma, Dennis H Bamford, David I Stuart, Jonathan M Grimes
  Acta Crystallographica Section D Biological Crystallography 04/2004; 60(Pt 3):588-90. · 12.62 Impact Factor
• Source

  Available from: ncbi.nlm.nih.gov

  Article: Cryoelectron microscopy of mouse mammary tumor virus.

  John A G Briggs, Barbara E Watson, Brent E Gowen, Stephen D Fuller
  Journal of Virology 04/2004; 78(5):2606-8. · 5.40 Impact Factor
• Article: Structure of the 'open' form of Aspergillus nidulans 3-dehydroquinate synthase at 1.7 A resolution from crystals grown following enzyme turnover.

  C E Nichols, A R Hawkins, D K Stammers
  Acta Crystallographica Section D Biological Crystallography 06/2004; 60(Pt 5):971-3. · 12.62 Impact Factor
• Article: The stoichiometry of Gag protein in HIV-1.

  John A G Briggs, Martha N Simon, Ingolf Gross, Hans-Georg Kräusslich, Stephen D Fuller, Volker M Vogt, Marc C Johnson
  Nature Structural &#38 Molecular Biology 08/2004; 11(7):672-5. · 12.71 Impact Factor
• Article: Crystal structures of Staphylococcus aureus type I dehydroquinase from enzyme turnover experiments.

  C E Nichols, M Lockyer, A R Hawkins, D K Stammers
  Proteins Structure Function and Bioinformatics 09/2004; 56(3):625-8. · 3.39 Impact Factor
• Article: High-resolution structures reveal details of domain closure and "half-of-sites-reactivity" in Escherichia coli aspartate beta-semialdehyde dehydrogenase.

  C E Nichols, B Dhaliwal, M Lockyer, A R Hawkins, D K Stammers
  Journal of Molecular Biology 09/2004; 341(3):797-806. · 4.00 Impact Factor
• Source

  Available from: kanazawa-u.ac.jp

  Article: Atomic snapshots of an RNA packaging motor reveal conformational changes linking ATP hydrolysis to RNA translocation.

  Erika J Mancini, Denis E Kainov, Jonathan M Grimes, Roman Tuma, Dennis H Bamford, David I Stuart
  Cell 10/2004; 118(6):743-55. · 32.40 Impact Factor
• Article: Crystallographic studies of shikimate binding and induced conformational changes in Mycobacterium tuberculosis shikimate kinase.

  Balvinder Dhaliwal, Charles E Nichols, Jingshan Ren, Michael Lockyer, Ian Charles, Alastair R Hawkins, David K Stammers
  FEBS Letters 10/2004; 574(1-3):49-54. · 3.54 Impact Factor
• Article: Comparison of ligand-induced conformational changes and domain closure mechanisms, between prokaryotic and eukaryotic dehydroquinate synthases.

  C E Nichols, J Ren, K Leslie, B Dhaliwal, M Lockyer, I Charles, A R Hawkins, D K Stammers
  Journal of Molecular Biology 11/2004; 343(3):533-46. · 4.00 Impact Factor
• Source

  Available from: calstatela.edu

  Article: Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 1.

  Andrew L Hopkins, Jingshan Ren, John Milton, Richard J Hazen, Joseph H Chan, David I Stuart, David K Stammers
  Journal of Medicinal Chemistry 11/2004; 47(24):5912-22. · 5.25 Impact Factor
• Source

  Available from: Sarah Butcher

  Article: Insights into assembly from structural analysis of bacteriophage PRD1.

  Nicola G A Abrescia, Joseph J B Cockburn, Jonathan M Grimes, Geoffrey C Sutton, Jonathan M Diprose, Sarah J Butcher, Stephen D Fuller, Carmen San Martín, Roger M Burnett, David I Stuart, Dennis H Bamford, Jaana K H Bamford
  Nature 12/2004; 432(7013):68-74. · 36.28 Impact Factor
• Article: Membrane structure and interactions with protein and DNA in bacteriophage PRD1.

  Joseph J B Cockburn, Nicola G A Abrescia, Jonathan M Grimes, Geoffrey C Sutton, Jonathan M Diprose, James M Benevides, George J Thomas, Jaana K H Bamford, Dennis H Bamford, David I Stuart
  Nature 12/2004; 432(7013):122-5. · 36.28 Impact Factor
• Article: Classification and three-dimensional reconstruction of unevenly distributed or symmetry mismatched features of icosahedral particles

  John A.G. Briggs, Juha T. Huiskonen, K. Vince Fernando, Robert J.C. Gilbert, Paul Scotti, Sarah J. Butcher, Stephen D. Fuller
  Journal of Structural Biology. 01/2005; 150(3):332-339.
• Article: Going soft and SAD with manganese.

  Paula S Salgado, Martin A Walsh, Minni R L Laurila, David I Stuart, Jonathan M Grimes
  Acta Crystallographica Section D Biological Crystallography 02/2005; 61(Pt 1):108-11. · 12.62 Impact Factor