Pamplona, Navarra, Spain

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Department of Nutrition, Food Science and Physiology
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IESE Business School
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Division of Gene Therapy and Hepatology
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    ABSTRACT: This paper proposes a genetic algorithm-based method for sizing the energy storage system (ESS) in microgrids. The main goal of the proposed method is to find the energy and power capacities of the storage system that minimizes the operating cost of the microgrid. The energy management strategy (EMS) used in this paper is based on a fuzzy expert system which is responsible for setting the power output of the ESS. The design of the EMS is carried out by means of a genetic algorithm that is used to set the fuzzy rules and membership functions of the expert system. Given that the size of the storage system has a major influence on the energy management strategy, in this paper the EMS and ESS capacities are jointly optimized. In addition, the proposed method uses an aging model to predict the lifetime of the ESS. In this way it is possible to determine the cost associated with energy storage in a more precise manner. The unit commitment problem, which is crucial for the proper operation of the microgrid, has been also considered in the present work. The suggested sizing methodology has been validated in two case studies.
    Renewable Energy 05/2015; 77:539-549. DOI:10.1016/j.renene.2014.12.039
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    ABSTRACT: Hydroponic experiments were conducted to investigate the variation of root exudates from the hyperaccumulator Sedum alfredii under the stress of cadmium (Cd). S. alfredii was cultured for 4 days in the nutrient solution spiked with CdCl2 at concentrations of 0, 5, 10, 40, and 400 µM Cd after the pre-culture. The root exudates were collected and analyzed by GC-MS, and 62 compounds were identified. Of these compounds, the orthogonal partial least-squares discrimination analysis (OPLS-DA) showed that there were a distinct difference among the root exudates with different Cd treatments and 20 compounds resulting in this difference were found out. Changing tendencies in the relative content of these 20 compounds under the different Cd treatments were analyzed. These results indicated that trehalose, erythritol, naphthalene, d-pinitol and n-octacosane might be closely related to the Cd stabilization, phosphoric acid, tetradecanoic acid, oxalic acid, threonic acid and glycine could be attributed to the Cd mobilization, and mannitol, oleic acid, 3-hydroxybutanoic acid, fructose, octacosanol and ribitol could copy well with the Cd stress.
    PLoS ONE 12/2014; 9(12):e115581. DOI:10.1371/journal.pone.0115581
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    ABSTRACT: Recently, super-resolution microscopy methods such as stochastic optical reconstruction microscopy (STORM) have enabled visualization of subcellular structures below the optical resolution limit. Due to the poor temporal resolution, however, these methods have mostly been used to image fixed cells or dynamic processes that evolve on slow time-scales. In particular, fast dynamic processes and their relationship to the underlying ultrastructure or nanoscale protein organization cannot be discerned. To overcome this limitation, we have recently developed a correlative and sequential imaging method that combines live-cell and super-resolution microscopy. This approach adds dynamic background to ultrastructural images providing a new dimension to the interpretation of super-resolution data. However, currently, it suffers from the need to carry out tedious steps of sample preparation manually. To alleviate this problem, we implemented a simple and versatile microfluidic platform that streamlines the sample preparation steps in between live-cell and super-resolution imaging. The platform is based on a microfluidic chip with parallel, miniaturized imaging chambers and an automated fluid-injection device, which delivers a precise amount of a specified reagent to the selected imaging chamber at a specific time within the experiment. We demonstrate that this system can be used for live-cell imaging, automated fixation, and immunostaining of adherent mammalian cells in situ followed by STORM imaging. We further demonstrate an application by correlating mitochondrial dynamics, morphology, and nanoscale mitochondrial protein distribution in live and super-resolution images.
    PLoS ONE 12/2014; 9(12):e115512. DOI:10.1371/journal.pone.0115512


  • Address
    Pio XII, 53, 31008, Pamplona, Navarra, Spain
  • Head of Institution
    D. Alfonso Sánchez-Tabernero
  • Website
  • Phone
    +34 948425600
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Top publications last week by downloads

Journal of Management 02/2011; 37(4). DOI:10.2139/ssrn.1674384

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