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    ABSTRACT: The statistical language R and its Bioconductor package are favoured by many biostatisticians for processing microarray data. The amount of data produced by some analyses has reached the limits of many common bioinformatics computing infrastructures. High Performance Computing systems offer a solution to this issue. The Simple Parallel R Interface (SPRINT) is a package that provides biostatisticians with easy access to High Performance Computing systems and allows the addition of parallelized functions to R. Previous work has established that the SPRINT implementation of an R permutation testing function has close to optimal scaling on up to 512 processors on a supercomputer. Access to supercomputers, however, is not always possible, and so the work presented here compares the performance of the SPRINT implementation on a supercomputer with benchmarks on a range of platforms including cloud resources and a common desktop machine with multiprocessing capabilities. Copyright © 2011 John Wiley & Sons, Ltd.
    Concurrency and Computation Practice and Experience 12/2011; 23(17):2258-2268.
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    ABSTRACT: This paper describes the integration of two ICL Distributed Array Processors (DAPs) into a dual ICL 2976 configuration running the Edinburgh Multi-Access System (EMAS). The principles underlying the general multi-access service are not compromised; special scheduling arrangements provide effective control and use of the DAP resource while allowing multi-user access to the DAPs for DAP program development.
    Software Practice and Experience 10/2006; 16(6):531 - 539.
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    ABSTRACT: To obtain data on seasonal variations of sperm parameters in an andrology laboratory. Semen parameter values and hormone values of 2454 patients attending our infertility clinic between 1990 and 1997 were analysed. Seasonal trends were calculated using the method of Edwards [Ann. Hum. Genet. 25 (1961) 83]. The total group of mean sperm count did not show a significant variation, but a significant circannual trend occurred of patients born in the groups 1950-1954, 1955-1959 and 1965-1969. A significant variation of acrosin activity occurred with a maximum in March. The other parameters did no show significant variations. The knowledge on circannual variation of semen parameters and hormone values may be of value in diagnostic and therapeutic decisions in reproductive medicine.
    European Journal of Obstetrics & Gynecology and Reproductive Biology 04/2002; 101(2):175-8.
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    ABSTRACT: Increasing interest is being shown in the use of Java for large scale or Grande applications. This new use of Java places speci.c demands on the Java execution environments that can be tested using the Java Grande benchmark suite [5], [6], [7]. The large processing requirements of Grande applications makes parallelisation of interest. A suite of parallel benchmarks has been developed from the serial Java Grande benchmark suite, using three parallel programming models: Java native threads, MPJ (a message passing interface) and JOMP (a set of OpenMP-like directives). The contents of the suite are described, and results presented for a number of platforms.
    Supercomputing, ACM/IEEE 2001 Conference; 12/2001
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    ABSTRACT: The nucleation of sodium, rubidium and potassium dodecyl sulphates are examined using temperature programmed milli-scale batch crystallisation experiments using optical turbidometry detection. As sodium dodecyl sulphate (SDS) crystallises as a hydrated system from aqueous solution, studies have also been carried out in the presence of sodium citrate, which causes the anhydrous phase to crystallise. The meta-stable zone widths (MSZW) and solution properties (the enthalpies and entropies of dissolution) as well as the nucleation reaction orders, are measured. The temperature of dissolution decreases with the decrease in cooling/heating rate whilst the temperature of crystallisation increases for all the systems, resulting in a decrease in the meta-stable zone width with decreasing temperature change rate. The enthalpies and entropies of dissolution of sodium, potassium and rubidium dodecyl sulphate increased with increasing alkali metal ionic radii. Very large values of MSZW for sodium citrate containing solutions occur. Extremely high reaction orders occur with SDS, at high concentrations when pure and at low concentrations when with sodium citrate.
    Journal of Crystal Growth 01/2001;
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    ABSTRACT: Between 1987 and 1994, more than 100 students in a broad range of disciplines worked as summer scholars at Edinburgh Parallel Computing Centre. Many of these students have since taken their parallel computing skills into graduate work and industry, and over a quarter of EPCC's technical staff are alumni of the Programme. This report describes the evolution and present operation of the Summer Scholarship Programme, and its costs and benefits
    Supercomputing '94. Proceedings; 12/1994
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    ABSTRACT: PARAMICS is a PARAllel MICroscopic Traffic Simulator which is, to our knowledge, the most powerful of its type in the world. The simulator can model around 200,000 vehicles on around 7,000 roads (taken from real road traffic network data) at faster than `real-time' rates, making use of 16 K processor TMC Connection Machine CM-200 for the simulation aspect. The project aims to make available to road network planners a new range of tools, and demonstrates that use of high performance computing in real applications is possible and worthwhile, while yielding important and interesting research results
    Supercomputing '94. Proceedings; 12/1994
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    ABSTRACT: The paper describes the Parallel Utilities Library (PUL) which has been in development at Edinburgh Parallel Computing Centre (EPCC) since 1991. The primary aim of this project has been to support the porting of commercial and industrial applications to parallel systems by providing commonly required services within a suite of library modules implemented on top of message-passing. The library includes support for task parallelism, domain decomposition, unstructured mesh applications and parallel scalable I/O and has recently been ported to the emerging Message-Passing Interface (MPI) standard. A large number of industrial application codes have been parallelised by making use of PUL and we report on three such projects that have been carried out with Rolls-Royce, AEA Technology and Shell UK
    Scalable Parallel Libraries Conference, 1994., Proceedings of the 1994; 11/1994
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    ABSTRACT: Modular application builders (MABs), such as AVS and Iris Explorer are increasingly being used in the visualization community. Such systems can already place compute intensive modules on supercomputers in order to utilize their power. This paper details two major projects at EPCC which attempted to fully integrate the MAB concept with a distributed memory MIMD (DM-MIMD) environment. The work presented was driven by two goals, efficient use of the resource and case of use by programmer and end user. We present a model of MABs and describe the major problems faced, giving solutions to them through two case studies
    Visualization, 1993. Visualization '93, Proceedings., IEEE Conference on; 11/1993
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    ABSTRACT: Terms associated with parallel and distributed computing technology are defined
    IEEE Parallel and Distributed Technology Systems and Applications 03/1993; 1(1):52-67.
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