Showa University

Shinagawa-ku, Japan

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Department of Obstetrics and Gynecology
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Department of Internal Medicine
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Department of Physiology
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    ABSTRACT: In Oriental medicine, the state of blood stagnation is called "Oketsu," meaning preceding state or symptomatic of sickness. Acupuncture stimulation is often used clinically for the treatment of "Oketsu." The degree of "Oketsu" is indicated by tongue color and form, swelling, paroxysmal blushing, and dark circles under the eyes. The blood’s fluidity is generally thought to be one of the blood stagnation factor. "Oketsu" is now considered as physiological blood flow and is studied from the perspective of the blood’s fluidity and vascular resistance. In our preliminary research, acupuncture stimuli were very effective in treating conditions associated with a decrease in the fluidity of the blood, such as "Oketsu." In this review, we discuss recent progress in acupuncture therapy and reported mechanisms of its action; we then focus on our original findings on these topics. Furthermore, we propose new factors related to acupuncture stimuli, including the blood’s fluidity, and report our investigations, using the restraint stress method, on the mechanisms underlying acupuncture stimuli.
    Journal of Acupuncture and Meridian Studies 08/2014;
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    ABSTRACT: Purpose Proper occlusal contact is important for the long-term success of prosthodontic therapy. We clarified the effects of occlusal loading force on occlusal contact in natural dentition by comparing measured values for occlusal loading and occlusal contact area. Methods Masseter muscle activity was measured in 10 subjects (2 male, 8 female; mean age, 27 years) with natural dentition using electromyography, with clenching at full strength with nothing interposed between the upper and lower teeth defined as 100% maximum voluntary contraction (MVC). Pressure-sensitive film (Occluzer) was used to examine occlusal contact points at 20, 40, 60, 80, 100 and 120% MVC. A material for checking accuracy of fit (BiteEye) was used to examine occlusal contact points at 20, 40, 60 and 80% MVC. ANOVA and the Bonferroni method were used to assess the results, with the level of significance set at 5%. Coefficients of variation (CV) were also calculated by dividing the standard deviation by the mean. Results Occlusal loading and occlusal contact area increased with clenching strength; however, CV showed differences between the methods at low and high MVC. Conclusions With Occluzer, testing should be carried out at clenching strength ≥60% MVC. With BiteEye, testing should be carried out from light clenching strength at 20% MVC to moderate clenching strengths at 40–60% MVC. Occluzer and BiteEye (10 μm) gave similar occlusal contact areas at 60–80% MVC. These results suggest that combined use of Occluzer and BiteEye gives an accurate picture of occlusion from weak to strong clenching strength.
    Journal of Prosthodontic Research 08/2014;
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    ABSTRACT: Pneumonia is a leading cause of death among elderly patients. Although aspiration pneumonia (AP) commonly occurs with aging, its clinical features and outcomes are still uncertain. The aims of this study were to describe the clinical features and outcomes of AP and to assess whether presence of AP affects clinical outcomes in patients with community-acquired pneumonia (CAP) and healthcare-associated pneumonia (HCAP). We retrospectively analyzed patients with CAP and HCAP hospitalized in our institution in Japan from October 2010 to March 2012. We compared clinical features and outcomes between AP and non-AP, and investigated risk factors for recurrence of pneumonia and death. Of 214 consecutive patients, 100 (46.7%) were diagnosed as having aspiration pneumonia. These patients were older and had lower body mass index, more comorbidities, and poorer Eastern Cooperative Oncology Group performance status (ECOG PS) than the patients with non-AP. Patients with AP had more severe disease, required longer hospital stays, and had a frequent recurrence rate of pneumonia and higher mortality. In multivariate analyses, AP, age, and ECOG PS were related to recurrence of pneumonia, and the prognostic factors were CURB-65 score and ECOG PS. AP was not a significant indicator for prognosis but was the strongest risk factor for recurrence of pneumonia. Clinical background and outcomes including recurrence and mortality of AP were obviously different from those of non-AP; therefore AP should be considered as a distinct subtype of pneumonia, and it is important to prevent the recurrence of pneumonia in the patients with AP.
    Journal of Infection and Chemotherapy 05/2014;


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    Shinagawa-ku, Japan
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Top publications last week by downloads

Annals of thoracic and cardiovascular surgery: official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia 04/2003; 9(2):98-104.
Biochemical Society Transactions 03/2000; 28(2):33-41.

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