Department of Medical and Molecular Genetics

Publications (230)

• Article: WAMIDEX: a web atlas of murine genomic imprinting and differential expression.

  Reiner Schulz, Kathryn Woodfine, Trevelyan R Menheniott, Deborah Bourc'his, Timothy Bestor, Rebecca J Oakey
  Epigenetics: official journal of the DNA Methylation Society 3(2):89-96. · 4.58 Impact Factor
• Source

  Available from: fly-bay.net

  Article: Correlation of DNA methylation with histone modifications across the HNRPA2B1-CBX3 ubiquitously-acting chromatin open element (UCOE).

  Marianne Lindahl Allen, Michael Antoniou
  Epigenetics: official journal of the DNA Methylation Society 2(4):227-36. · 4.58 Impact Factor
• Article: DMSO and retinoic acid induce HL-60 differentiation by different but converging pathways.

  K E Van Roozendaal, D Darling, F Farzaneh
  Experimental Cell Research 10/1990; 190(1):137-40. · 3.58 Impact Factor
• Article: Formation of polyglutamine inclusions in non-CNS tissue.

  K Sathasivam, C Hobbs, M Turmaine, L Mangiarini, A Mahal, F Bertaux, E E Wanker, P Doherty, S W Davies, G P Bates
  Human Molecular Genetics 06/1999; 8(5):813-22. · 7.64 Impact Factor
• Article: Transgenic models of Huntington's disease.

  K Sathasivam, C Hobbs, L Mangiarini, A Mahal, M Turmaine, P Doherty, S W Davies, G P Bates
  Philosophical Transactions of The Royal Society B Biological Sciences 07/1999; 354(1386):963-9. · 6.40 Impact Factor
• Article: An interstitial deletion of 6p24-p25 proximal to the FKHL7 locus and including AP-2alpha that affects anterior eye chamber development.

  A F Davies, G Mirza, F Flinter, J Ragoussis
  Journal of Medical Genetics 10/1999; 36(9):708-10. · 6.36 Impact Factor
• Article: Erythropoiesis: Current Clinical Practice: Advances in the Genetics and Biology of Fanconi Anaemia.

  A. J. Tipping, C. G. Mathew
  Hematology (Amsterdam, Netherlands) 02/2000; 5(1):1-13. · 1.33 Impact Factor
• Article: Construction of a high-resolution 2.5-Mb transcript map of the human 6p21.2-6p21.3 region immediately centromeric of the major histocompatibility complex.

  N Tripodis, S Palmer, S Phillips, S Milne, S Beck, J Ragoussis
  Genome Research 05/2000; 10(4):454-72. · 13.61 Impact Factor
• Article: Screening for mutations of Bcl10 in leukaemia.

  D Grimwade, M Q Du, S Langabeer, J Rogers, E Solomon
  British Journal of Haematology 07/2000; 109(3):611-5. · 4.94 Impact Factor
• Article: Celiac disease and human leukocyte antigen genotype: accuracy of diagnosis in self-diagnosed individuals, dosage effect, and sibling risk.

  C Lewis, L Book, J Black, A Sawitzke, L Cannon-Albright, J Zone, S Neuhausen
  Journal of Pediatric Gastroenterology and Nutrition 08/2000; 31(1):22-7. · 2.30 Impact Factor
• Article: The X chromosome and the rate of deleterious mutations in humans.

  F Giannelli, P M Green
  The American Journal of Human Genetics 09/2000; 67(2):515-7. · 10.60 Impact Factor
• Article: A mitotically stable marker chromosome negative for whole chromosome libraries, centromere probes and chromosome specific telomere regions: a novel class of supernumerary marker chromosome?

  C Mackie Ogilvie, R H Harrison, S W Horsley, S V Hodgson, L Kearney
  Cytogenetics and cell genetics 02/2001; 92(1-2):69-73.
• Article: Embryonic stem cell research. The case against...

  M Antoniou
  Nature Medicine 05/2001; 7(4):397-9. · 22.46 Impact Factor
• Article: The minisatellite of the GPI/AMF/NLK/MF gene: interspecies conservation and transcriptional activity.

  R R Williams, A F Hassan-Walker, F L Lavender, M Morgan, P Faik, J Ragoussis
  Gene 06/2001; 269(1-2):81-92. · 2.34 Impact Factor
• Article: Centrosome disorganization in fibroblast cultures derived from R6/2 Huntington's disease (HD) transgenic mice and HD patients.

  K Sathasivam, B Woodman, A Mahal, F Bertaux, E E Wanker, D T Shima, G P Bates
  Human Molecular Genetics 11/2001; 10(21):2425-35. · 7.64 Impact Factor
• Article: Haemophilia. Gene mutations and pedigrees.

  F Giannelli
  The Lancet 01/2002; 358 Suppl:S33. · 38.28 Impact Factor
• Article: Haemophilia. This bad blood.

  P M Green
  The Lancet 01/2002; 358 Suppl:S34. · 38.28 Impact Factor
• Article: Environmental enrichment slows disease progression in R6/2 Huntington's disease mice.

  Emma Hockly, Patricia M Cordery, Benjamin Woodman, Amarbirpal Mahal, Anton van Dellen, Colin Blakemore, Cathryn M Lewis, Anthony J Hannan, Gillian P Bates
  Annals of Neurology 03/2002; 51(2):235-42. · 11.09 Impact Factor
• Article: Germline BRCA1 promoter deletions in UK and Australian familial breast cancer patients: Identification of a novel deletion consistent with BRCA1:psiBRCA1 recombination.

  Melissa A Brown, Li-Jan Lo, Aurélie Catteau, Chun-Fang Xu, Geoffrey J Lindeman, Shirley Hodgson, Ellen Solomon
  Human Mutation 05/2002; 19(4):435-42. · 5.69 Impact Factor
• Article: Sex stratification of an inflammatory bowel disease genome search shows male-specific linkage to the HLA region of chromosome 6.

  Sheila A Fisher, Jochen Hampe, Andrew J S Macpherson, Alastair Forbes, John E Lennard-Jones, Stefan Schreiber, Mark E Curran, Christopher G Mathew, Cathryn M Lewis
  European Journal of HumanGenetics 05/2002; 10(4):259-65. · 4.40 Impact Factor
• Article: Microdeletion 22q11.2, Kousseff syndrome and spina bifida.

  Mary J Seller, Shehla Mohammed, Jo Russell, Caroline Ogilvie
  Clinical Dysmorphology 05/2002; 11(2):113-5. · 0.54 Impact Factor
• Article: Imprinted genes: identification by chromosome rearrangements and post-genomic strategies.

  Rebecca J Oakey, Colin V Beechey
  Trends in Genetics 08/2002; 18(7):359-66. · 10.06 Impact Factor
• Article: The T-lineage-affiliated CD2 gene lies within an open chromatin environment in acute promyelocytic leukemia cells.

  David Grimwade, Susan V Outram, Rajinder Flora, Stuart J Ings, Arnold R Pizzey, Ricardo Morilla, Charles F Craddock, David C Linch, Ellen Solomon
  Cancer Research 09/2002; 62(16):4730-5. · 7.86 Impact Factor
• Article: Immunological weapons against acute myeloid leukaemia.

  Joanna Galea-Lauri
  Immunology 10/2002; 107(1):20-7. · 3.32 Impact Factor
• Article: Expression of a truncated Brca1 protein delays lactational mammary development in transgenic mice.

  Melissa A Brown, Hans Nicolai, Kathy Howe, Toyomasa Katagiri, El-Nasir Lalani, Kaylene J Simpson, Nathan W Manning, Andrew Deans, Phil Chen, Kum Kum Khanna, Mas Rina Wati, Beatrice L Griffiths, Chun-Fang Xu, Gordon W H Stamp, Ellen Solomon
  Transgenic Research 11/2002; 11(5):467-78. · 2.75 Impact Factor
• Article: cDNA cloning, expression profile and genomic structure of a novel human transcript on chromosome 10q24, and its analyses as a candidate gene for infantile onset spinocerebellar ataxia.

  Kaisu Nikali, Juha Saharinen, Leena Peltonen
  Gene 11/2002; 299(1-2):111-5. · 2.34 Impact Factor
• Article: Unusual deep intronic mutations in the COL4A5 gene cause X linked Alport syndrome.

  Kathy King, Frances A Flinter, Vandana Nihalani, Peter M Green
  Human Genetics 01/2003; 111(6):548-54. · 5.07 Impact Factor
• Source

  Available from: pnas.org

  Article: Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease.

  Emma Hockly, Victoria M Richon, Benjamin Woodman, Donna L Smith, Xianbo Zhou, Eddie Rosa, Kirupa Sathasivam, Shabnam Ghazi-Noori, Amarbirpal Mahal, Philip A S Lowden, Joan S Steffan, J Lawrence Marsh, Leslie M Thompson, Cathryn M Lewis, Paul A Marks, Gillian P Bates
  Proceedings of the National Academy of Sciences 03/2003; 100(4):2041-6. · 9.68 Impact Factor
• Source

  Available from: Alastair Forbes

  Article: Genetic evidence for interaction of the 5q31 cytokine locus and the CARD15 gene in Crohn disease.

  Muddassar M Mirza, Sheila A Fisher, Kathy King, Andrew P Cuthbert, Jochen Hampe, Jeremy Sanderson, John Mansfield, Peter Donaldson, Andrew J S Macpherson, Alastair Forbes, Stefan Schreiber, Cathryn M Lewis, Christopher G Mathew
  The American Journal of Human Genetics 05/2003; 72(4):1018-22. · 10.60 Impact Factor
• Article: Huntingtin aggregation and toxicity in Huntington's disease.

  Gillian Bates
  The Lancet 06/2003; 361(9369):1642-4. · 38.28 Impact Factor
• Article: Minocycline and doxycycline are not beneficial in a model of Huntington's disease.

  Donna L Smith, Benjamin Woodman, Amarbirpal Mahal, Kirupa Sathasivam, Shabnam Ghazi-Noori, Philip A S Lowden, Gillian P Bates, Emma Hockly
  Annals of Neurology 09/2003; 54(2):186-96. · 11.09 Impact Factor
• Article: Experimental therapeutics in Huntington's disease: are models useful for therapeutic trials?

  Gillian P Bates, Emma Hockly
  Current Opinion in Neurology 09/2003; 16(4):465-70. · 4.94 Impact Factor
• Article: Standardization and statistical approaches to therapeutic trials in the R6/2 mouse.

  Emma Hockly, Benjamin Woodman, Amarbirpal Mahal, Cathryn M Lewis, Gillian Bates
  Brain Research Bulletin 10/2003; 61(5):469-79. · 2.82 Impact Factor
• Source

  Available from: upatras.gr

  Article: Transgenes encompassing dual-promoter CpG islands from the human TBP and HNRPA2B1 loci are resistant to heterochromatin-mediated silencing.

  Michael Antoniou, Lee Harland, Tracey Mustoe, Steven Williams, Jolyon Holdstock, Ernesto Yague, Tony Mulcahy, Mark Griffiths, Sian Edwards, Panayiotis A Ioannou, Andrew Mountain, Robert Crombie
  Genomics 10/2003; 82(3):269-79. · 3.02 Impact Factor
• Article: Elevated levels of beta defensin-1 mRNA in diabetic kidneys of GK rats.

  Rachel A Page, Afshan N Malik
  Biochemical and Biophysical Research Communications 11/2003; 310(2):513-21. · 2.48 Impact Factor
• Source

  Available from: vu.nl

  Article: Bi-allelic silencing of the Fanconi anaemia gene FANCF in acute myeloid leukaemia.

  Marc Tischkowitz, Najim Ameziane, Quinten Waisfisz, Johan P De Winter, Richard Harris, Toshiyasu Taniguchi, Alan D'Andrea, Shirley V Hodgson, Christopher G Mathew, Hans Joenje
  British Journal of Haematology 12/2003; 123(3):469-71. · 4.94 Impact Factor
• Article: A trisomy 2 fetus with severe neural tube defects and other abnormalities.

  Mary J Seller, Roberto Mazzaschi, Caroline Mackie Ogilvie, Shehla Mohammed
  Clinical Dysmorphology 02/2004; 13(1):25-7. · 0.54 Impact Factor
• Article: Mouse models of triplet repeat diseases.

  Gillian P Bates, David G Hay
  Methods in molecular biology (Clifton, N.J.) 02/2004; 277:3-15.
• Article: Monitoring aggregate formation in organotypic slice cultures from transgenic mice.

  Donna L Smith, Gillian P Bates
  Methods in molecular biology (Clifton, N.J.) 02/2004; 277:161-71.
• Article: Deletion and reduced expression of the Fanconi anemia FANCA gene in sporadic acute myeloid leukemia.

  M D Tischkowitz, N V Morgan, D Grimwade, C Eddy, S Ball, I Vorechovsky, S Langabeer, R Stöger, S V Hodgson, C G Mathew
  Leukemia 03/2004; 18(3):420-5. · 9.56 Impact Factor
• Article: Brca1 expression is regulated by a bidirectional promoter that is shared by the Nbr1 gene in mouse.

  Caroline Whitehouse, Julie Chambers, Aurélie Catteau, Ellen Solomon
  Gene 03/2004; 326:87-96. · 2.34 Impact Factor
• Article: Acute promyelocytic leukemia: where does it stem from?

  D Grimwade, T Enver
  Leukemia 04/2004; 18(3):375-84. · 9.56 Impact Factor
• Article: BRCA1 : BARD1 induces the formation of conjugated ubiquitin structures, dependent on K6 of ubiquitin, in cells during DNA replication and repair.

  Joanna R Morris, Ellen Solomon
  Human Molecular Genetics 05/2004; 13(8):807-17. · 7.64 Impact Factor
• Article: Genetics of inflammatory bowel disease: progress and prospects.

  Christopher G Mathew, Cathryn M Lewis
  Human Molecular Genetics 05/2004; 13 Spec No 1:R161-8. · 7.64 Impact Factor
• Article: Progressive decrease in chaperone protein levels in a mouse model of Huntington's disease and induction of stress proteins as a therapeutic approach.

  David G Hay, Kirupa Sathasivam, Sönke Tobaben, Bernd Stahl, Michael Marber, Ruben Mestril, Amarbirpal Mahal, Donna L Smith, Ben Woodman, Gillian P Bates
  Human Molecular Genetics 08/2004; 13(13):1389-405. · 7.64 Impact Factor
• Article: Trisomy 16 in a mid-trimester IVF foetus with multiple abnormalities.

  Mary J Seller, Claudine Fear, Ajith Kumar, Shehla Mohammed
  Clinical Dysmorphology 08/2004; 13(3):187-9. · 0.54 Impact Factor
• Source

  Available from: Roland G Roberts

  Article: Multiplex ligation-dependent probe amplification using a completely synthetic probe set.

  Rowena F Stern, Roland G Roberts, Kathy Mann, Shu C Yau, Jonathan Berg, Caroline Mackie Ogilvie
  BioTechniques 10/2004; 37(3):399-405. · 2.67 Impact Factor
• Source

  Available from: ncbi.nlm.nih.gov

  Article: Huntingtin and the molecular pathogenesis of Huntington's disease. Fourth in molecular medicine review series.

  Christian Landles, Gillian P Bates
  EMBO Reports 11/2004; 5(10):958-63. · 7.36 Impact Factor
• Article: Strategies for antigen choice and priming of dendritic cells influence the polarization and efficacy of antitumor T-cell responses in dendritic cell-based cancer vaccination.

  Joanna Galea-Lauri, James W Wells, David Darling, Phillip Harrison, Farzin Farzaneh
  Cancer Immunology and Immunotherapy 12/2004; 53(11):963-77. · 3.70 Impact Factor
• Article: Structural evolution of the BRCA1 genomic region in primates.

  Hong Jin, Joanna Selfe, Caroline Whitehouse, Joanna R Morris, Ellen Solomon, Roland G Roberts
  Genomics 01/2005; 84(6):1071-82. · 3.02 Impact Factor