Division of Cell and Molecular Biology

Publications (443)

• Article: Purification and properties of monomeric (G1) forms of acetylcholinesterase secreted by Nippostrongylus brasiliensis

  Michael E Grigg, Liang Tang, Ayman S Hussein, Murray E Selkirk
  Molecular and Biochemical Parasitology.
• Article: Think zinc: New roles for zinc in the control of insulin secretion.

  Guy A Rutter
  Islets 2(1):49-50.
• Article: Antibodies targeting cancer stem cells: a new paradigm in immunotherapy?

  Mahendra P Deonarain, Christina A Kousparou, Agamemnon A Epenetos
  mAbs 1(1):12-25.
• Article: Nippostrongylus brasiliensis:Characterisation of a Somatic Amphiphilic Acetylcholinesterase with Properties Distinct from the Secreted Enzymes

  Ayman S. Hussein, Michael E. Grigg, Murray E. Selkirk
  Experimental Parasitology.
• Article: Plasmodium male development gene-1 (mdv-1) is important for female sexual development and identifies a polarised plasma membrane during zygote development

  Kalpana Lal, Michael J. Delves, Elizabeth Bromley, Jonathan M. Wastling, Fiona M. Tomley, Robert E. Sinden
  International Journal for Parasitology.
• Article: Electrophysiological, mechanosensitive responses of Xenopus laevis oocytes to direct, isotonic increase in intracellular volume

  Andrea A. Bryan-Sisneros, S.P. Fraser, M.B.A. Djamgoz
  Journal of Neuroscience Methods.
• Article: Interactions between long-acting β2-agonists and glucocorticoids

  Gaetano Caramori, Kazuhiro Ito, Alberto Papi, Ian M. Adcock
  Drug Discovery Today: Therapeutic Strategies.
• Article: Cell–cell adhesion and signalling

  Vania M.M Braga
  Current Opinion in Cell Biology.
• Article: Effect of glutamate on extracellular potassium activity in isolated retina of cyprinid fish.

  M B Djamgoz
  Neurochemistry International 01/1988; 13(4):439-48. · 2.86 Impact Factor
• Article: Glutamate-induced K+ flux in the photoreceptor layer of isolated retina of cyprinid fish: possible consequences for second-order neurones.

  M B Djamgoz
  Physiologia Bohemoslovaca 02/1988; 37(3):235-9.
• Article: Differential recovery rates of horizontal and amacrine cell responses from intense irradiation in the isolated retina of cyprinid fish.

  M B Djamgoz
  Neuroscience Letters 07/1988; 88(3):263-70. · 2.11 Impact Factor
• Article: Membrane currents induced in Xenopus oocytes by the C-terminal fragment of the beta-amyloid precursor protein.

  S P Fraser, Y H Suh, Y H Chong, M B Djamgoz
  Journal of Neurochemistry 06/1996; 66(5):2034-40. · 4.06 Impact Factor
• Article: Ionic effects of the Alzheimer's disease beta-amyloid precursor protein and its metabolic fragments.

  S P Fraser, Y H Suh, M B Djamgoz
  Trends in Neurosciences 03/1997; 20(2):67-72. · 14.23 Impact Factor
• Article: Hyaluronan activates calcium-dependent chloride currents in Xenopus oocytes.

  S P Fraser
  FEBS Letters 04/1997; 404(1):56-60. · 3.54 Impact Factor
• Article: G-protein activation, intracellular Ca2+ mobilization and phosphorylation studies of membrane currents induced by AlF4- in Xenopus oocytes.

  C Moon, S P Fraser, M B Djamgoz
  Cellular Signalling 12/1997; 9(7):497-504. · 4.06 Impact Factor
• Article: Neurobiology of retinal dopamine in relation to degenerative states of the tissue.

  M B Djamgoz, M W Hankins, J Hirano, S N Archer
  Vision Research 01/1998; 37(24):3509-29. · 2.41 Impact Factor
• Article: Electrophysiological characterization of voltage-gated Na+ current expressed in the highly metastatic Mat-LyLu cell line of rat prostate cancer.

  J A Grimes, M B Djamgoz
  Journal of Cellular Physiology 05/1998; 175(1):50-8. · 3.87 Impact Factor
• Article: Effects of gadolinium ions upon rat prostatic cancer cell lines of markedly different metastatic potential.

  J Verrall, S P Fraser, M B Djamgoz
  Cancer Letters 11/1999; 145(1-2):79-83. · 4.24 Impact Factor
• Article: Protein kinase and phosphatase modulation of quail brain GABA(A) and non-NMDA receptors co-expressed in Xenopus oocytes.

  C Moon, S P Fraser, M B Djamgoz
  Cellular Signalling 03/2000; 12(2):105-12. · 4.06 Impact Factor
• Article: Effects of voltage‐gated ion channel modulators on rat prostatic cancer cell proliferation: Comparison of strongly and weakly metastatic cell lines

  S.P. Fraser, J.A. Grimes, M.B.A. Djamgoz
  The Prostate 06/2000; 44(1):61 - 76. · 3.48 Impact Factor
• Article: Effects of voltage-gated ion channel modulators on rat prostatic cancer cell proliferation: comparison of strongly and weakly metastatic cell lines.

  S P Fraser, J A Grimes, M B Djamgoz
  The Prostate 07/2000; 44(1):61-76. · 3.48 Impact Factor
• Article: A novel missense mutation (L198R) in the Friedreich's ataxia gene.

  S Al-Mahdawi, M Pook, S Chamberlain
  Human Mutation 08/2000; 16(1):95. · 5.69 Impact Factor
• Article: Toxic effect of the beta-amyloid precursor protein C-terminus fragment and Na+/Ca2+ gradients.

  A A Bryan-Sisneros, S P Fraser, Y H Suh, M B Djamgoz
  Neuroreport 11/2000; 11(15):3357-60. · 1.66 Impact Factor
• Article: Archaeal RNA polymerase subunits F and P are bona fide homologs of eukaryotic RPB4 and RPB12

  Finn Werner, Jyrki J. Eloranta, Robert O J Weinzierl
  Nucleic Acids Research 12/2000; · 8.03 Impact Factor
• Source

  Available from: José S Ramalho

  Article: Chromosomal mapping, gene structure and characterization of the human and murine RAB27B gene.

  J S Ramalho, T Tolmachova, A N Hume, A McGuigan, C Y Gregory-Evans, C Huxley, M C Seabra
  BMC Genetics 02/2001; 2:2. · 2.47 Impact Factor
• Article: Thrombospondin-1 is the key activator of TGF-beta1 in human mesangial cells exposed to high glucose.

  N Yevdokimova, N A Wahab, R M Mason
  Journal of the American Society of Nephrology 05/2001; 12(4):703-12. · 9.66 Impact Factor
• Article: Prenylation of Rab GTPases: molecular mechanisms and involvement in genetic disease.

  J B Pereira-Leal, A N Hume, M C Seabra
  FEBS Letters 07/2001; 498(2-3):197-200. · 3.54 Impact Factor
• Article: 'Super glue'.

  V Braga, A J Harwood
  Nature Cell Biology 08/2001; 3(7):E168-70. · 19.49 Impact Factor
• Article: Temporal and spatial expression patterns of the CRX transcription factor and its downstream targets. Critical differences during human and mouse eye development.

  L C Bibb, J K Holt, E E Tarttelin, M D Hodges, K Gregory-Evans, A Rutherford, R J Lucas, J C Sowden, C Y Gregory-Evans
  Human Molecular Genetics 08/2001; 10(15):1571-9. · 7.64 Impact Factor
• Article: Expression profiles of voltage-gated Na(+) channel alpha-subunit genes in rat and human prostate cancer cell lines.

  J K Diss, S N Archer, J Hirano, S P Fraser, M B Djamgoz
  The Prostate 09/2001; 48(3):165-78. · 3.48 Impact Factor
• Source

  Available from: nih.gov

  Article: Role of connective tissue growth factor in the pathogenesis of diabetic nephropathy.

  N A Wahab, N Yevdokimova, B S Weston, T Roberts, X J Li, H Brinkman, R M Mason
  Biochemical Journal 10/2001; 359(Pt 1):77-87. · 4.90 Impact Factor
• Source

  Available from: nih.gov

  Article: Uptake and intracellular transport of the connective tissue growth factor: a potential mode of action.

  N A Wahab, H Brinkman, R M Mason
  Biochemical Journal 11/2001; 359(Pt 1):89-97. · 4.90 Impact Factor
• Article: Rescue of the Friedreich's ataxia knockout mouse by human YAC transgenesis.

  M A Pook, S Al-Mahdawi, C J Carroll, M Cossée, H Puccio, L Lawrence, P Clark, M B Lowrie, J L Bradley, J M Cooper, M Koenig, S Chamberlain
  Neurogenetics 11/2001; 3(4):185-93. · 3.35 Impact Factor
• Article: Bacitracin inhibits fibronectin matrix assembly by mesangial cells in high glucose.

  B S Weston, N A Wahab, T Roberts, R M Mason
  Kidney International 12/2001; 60(5):1756-64. · 6.61 Impact Factor
• Article: Evolution of the Rab family of small GTP-binding proteins.

  J B Pereira-Leal, M C Seabra
  Journal of Molecular Biology 12/2001; 313(4):889-901. · 4.00 Impact Factor
• Article: Analysis and preparation of stable complexes between Rab GTPases, Rab escort protein, and Rab geranylgeranyl transferase.

  José B Pereira-Leal, Anita Q Gomes, Miguel C Seabra
  Methods in molecular biology (Clifton, N.J.) 02/2002; 189:157-65.
• Article: Expression of collagen and aggrecan genes in normal and osteoarthritic murine knee joints.

  M G Chambers, T Kuffner, S K Cowan, K S E Cheah, R M Mason
  Osteoarthritis and Cartilage 02/2002; 10(1):51-61. · 3.90 Impact Factor
• Article: Characterization and purification of phosphatidylinositol trisphosphate 5-phosphatase from rat brain tissues.

  Rudiger Woscholski
  Methods in Enzymology 02/2002; 345:335-45. · 2.04 Impact Factor
• Article: Rab GTPases, intracellular traffic and disease.

  Miguel C Seabra, Emilie H Mules, Alistair N Hume
  Trends in Molecular Medicine 02/2002; 8(1):23-30. · 10.35 Impact Factor
• Source

  Available from: horizonpress.com

  Article: A vector with transcriptional terminators increases efficiency of cloning of an RNA virus by reverse transcription long polymerase chain reaction.

  C L Cameron-Wilson, H Zhang, F Zhang, L Buluwela, P Muir, L C Archard
  Journal of Molecular Microbiology and Biotechnology 04/2002; 4(2):127-31. · 1.95 Impact Factor
• Article: Comparison of collagenase-cleaved articular cartilage collagen in mice in the naturally occurring STR/ort model of osteoarthritis and in collagen-induced arthritis.

  J S Price, M G Chambers, A R Poole, A Fradin, R M Mason
  Osteoarthritis and Cartilage 04/2002; 10(3):172-9. · 3.90 Impact Factor
• Article: The leaden gene product is required with Rab27a to recruit myosin Va to melanosomes in melanocytes.

  Alistair N Hume, Lucy M Collinson, Colin R Hopkins, Molly Strom, Duarte C Barral, Giovanna Bossi, Gillian M Griffiths, Miguel C Seabra
  Traffic 04/2002; 3(3):193-202. · 4.92 Impact Factor
• Source

  Available from: ncbi.nlm.nih.gov

  Article: Decorin suppresses transforming growth factor-beta-induced expression of plasminogen activator inhibitor-1 in human mesangial cells through a mechanism that involves Ca2+-dependent phosphorylation of Smad2 at serine-240.

  Nadia Abdel-Wahab, Stephen J Wicks, Roger M Mason, Andrew Chantry
  Biochemical Journal 04/2002; 362(Pt 3):643-9. · 4.90 Impact Factor
• Source

  Available from: oxfordjournals.org

  Article: Enterovirus replication in valvular tissue from patients with chronic rheumatic heart disease.

  Y Li, Z Pan, Y Ji, T Peng, L C Archard, H Zhang
  European Heart Journal 05/2002; 23(7):567-73. · 10.48 Impact Factor
• Article: YAC transgenic mice carrying pathological alleles of the MJD1 locus exhibit a mild and slowly progressive cerebellar deficit.

  Cemal K Cemal, Christopher J Carroll, Lorraine Lawrence, Margaret B Lowrie, Piers Ruddle, Sahar Al-Mahdawi, Rosalind H M King, Mark A Pook, Clare Huxley, Susan Chamberlain
  Human Molecular Genetics 06/2002; 11(9):1075-94. · 7.64 Impact Factor
• Article: Antibody-guided enzyme therapy of cancer producing cyanide results in necrosis of targeted cells.

  Christina A Kousparou, Agamemnon A Epenetos, Mahendra P Deonarain
  International Journal of Cancer 06/2002; 99(1):138-48. · 5.44 Impact Factor
• Source

  Available from: imperial.ac.uk

  Article: Suppression of secreted acetylcholinesterase expression in Nippostrongylus brasiliensis by RNA interference.

  Ayman S Hussein, Ketty Kichenin, Murray E Selkirk
  Molecular and Biochemical Parasitology 07/2002; 122(1):91-4. · 2.55 Impact Factor
• Article: Background potassium channels move into focus.

  Alistair Mathie, Catherine E Clarke
  The Journal of Physiology 08/2002; 542(Pt 2):334. · 4.72 Impact Factor
• Article: Assembly of the immunological synapse for T cells and NK cells.

  Daniel M Davis
  Trends in Immunology 08/2002; 23(7):356-63. · 10.40 Impact Factor
• Source

  Available from: José S Ramalho

  Article: Functional redundancy of Rab27 proteins and the pathogenesis of Griscelli syndrome.

  Duarte C Barral, José S Ramalho, Ross Anders, Alistair N Hume, Holly J Knapton, Tanya Tolmachova, Lucy M Collinson, David Goulding, Kalwant S Authi, Miguel C Seabra
  Journal of Clinical Investigation 08/2002; 110(2):247-57. · 15.39 Impact Factor