Imperial College London

London, United Kingdom

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Publication History View all

• Article: New Drug Therapies for COPD.
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ABSTRACT: Clinical trials with new drugs for chronic obstructive pulmonary disease (COPD) have been performed. Viruses exacerbate COPD and bacteria may play a part in severe COPD; therefore, antibiotic and antiviral approaches have a sound rationale. Antiinflammatory approaches have been studied. Advances in understanding the molecular basis of other processes have resulted in novel drugs to target reactive oxidant species, mucus, proteases, fibrosis, cachexia, and muscle wasting, and accelerated aging. Studies with monoclonal antibodies have been disappointing, highlighting the tendency for infections and malignancies during treatment. Promising future directions are lung regeneration with retinoids and stem cells.
Clinics in chest medicine 03/2014; 35(1):219-239.
• Article: Unexplained Recurrent Pregnancy Loss.
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ABSTRACT: Women with unexplained recurrent pregnancy loss (RPL) represent a highly heterogeneous group of patients. Past studies have investigated systemic endocrine and immunologic mechanisms as potential causes for pregnancy loss in unexplained RPL, while exciting new work has focused on spermatozoal, embryonic, and endometrial characteristics to explain the regulation of implantation and subsequent pregnancy loss. In the clinical and research context, stratification of women with unexplained RPL according to whether they have a high probability of pathologic status will help select women who are most appropriate for further investigation and potential future treatment.
Obstetrics and Gynecology Clinics of North America 03/2014; 41(1):157-166.
• Article: Lp-Nuclearity, traces, and Grothendieck-Lidskii formula on compact Lie groups
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ABSTRACT: Given a compact Lie group $G$, in this paper we give symbolic criteria for operators to be nuclear and r-nuclear on Lp-spaces, with applications to distribution of eigenvalues and trace formulae. Since criteria in terms of kernels are often not effective in view of Carleman's example, in this paper we adopt the symbolic point of view. The criteria here are given in terms of the concept of matrix symbols defined on the non-commutative analogue of the phase space $G\times\hat{G}$, where $\hat{G}$ is the unitary dual of $G$.
Journal de Mathématiques Pures et Appliqués 02/2014;

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South Kensington Campus, London, SW7 2AZ, London, United Kingdom
Sir Keith O’Nions
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www3.imperial.ac.uk
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 Modelling copulas: An overview 118 Downloads Cashmere-producing goats in Central Asia and Afghanistan Animal Genetic Resources Information. 09/2009; 45:15 - 27. 118 Downloads

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