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ABSTRACT: Background The incidence of lung cancer is reputed to be higher and prognosis worse in solid organ transplant recipients than in the general population. Our purpose was to review the results of surgery in this group of patients. Methods We retrospectively reviewed 49 male and 6 female patients; mean aged 60.6 years (38–85). Transplanted organ was heart (n = 37), kidney (n = 12), liver (n = 5) and both-lungs (n = 1); 48 patients had smoking habits and 42 heavy comorbidities (76.4%). Lung cancer was diagnosed during surveillance (78.2%, n = 43) or because of symptoms (21.8%, n = 12). We reviewed TNM and other main characteristics, among them histology (squamous-cell-carcinoma n= 23, adenocarcinomas n = 24, others n = 8). Results Surgery consisted of: exploratory thoracotomy (n = 2), wedge resections (n = 6), segmentectomy (n = 1), lobectomy (n = 42), pneumonectomy (n = 4). Postoperative mortality was 7.4% (n = 4) and complication rate 34.5% (n = 19). Five-year survival rate was 46.4% (65.4% for stage I patients, n = 25). Among the 35 dead patients during follow-up, 14 died of their lung cancer (40%). Two had been re-operated from another lung cancer: one after 3 and 8 years who survived 16 years, and the other after 2 years who survived 70 months. Conclusions Surgery results are good and postoperative events acceptable despite theoretically increased risks. This also supports performing a close follow-up of transplanted patients and particularly those with smoking history in view of detecting lung cancer appearing at an early stage.Revue de Pneumologie Clinique 12/2014; 70(6). DOI:10.1016/j.pneumo.2014.04.007
- Diagnostic and interventional imaging 11/2014; 95(11). DOI:10.1016/j.diii.2013.12.020
- European Annals of Otorhinolaryngology, Head and Neck Diseases 09/2014; 131(4). DOI:10.1016/j.anorl.2014.03.003
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